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31. 发明申请

WO2012126504A1 METHOD AND DEVICE FOR LINEARIZING A TRANSFORMER 审中-公开
标题翻译：用于线性化变压器的方法和装置
公开(公告)号：WO2012126504A1
公开(公告)日：2012-09-27
申请号：PCT/EP2011/054165
申请日：2011-03-18
申请人： ABB RESEARCH LTD , BENGTSSON, Tord , JOHANSSON, Henrik , ROXENBORG, Stefan , MENEZES, Joseph , NAGY, Zoltan , SEHLSTEDT, Mikael
发明人： BENGTSSON, Tord , JOHANSSON, Henrik , ROXENBORG, Stefan , MENEZES, Joseph , NAGY, Zoltan , SEHLSTEDT, Mikael
IPC分类号： G01R15/18 , H01F27/42 , G05F7/00 , H02H1/00
CPC分类号： H01F27/42
摘要： The present invention relates to a method for linearizing voltage transmission through a transformer including a magnetic core and, input and output windings. A measurement signal is supplied to the input winding at a first frequency and an output signal is measured at the output winding of the transformer, wherein the voltage of the measurement signal may be so low that the transformer operates in a non-linear region. The method comprises, for a conditioning signal, selecting a second frequency different from the first frequency (100), defining an amplitude value of the conditioning signal (110) and supplying the conditioning signal to the input winding at the second frequency with the defined amplitude value so that the transformer operates in its linear region (120).
摘要翻译：本发明涉及通过包括磁芯和输入和输出绕组的变压器线性化电压传输的方法。测量信号以第一频率提供给输入绕组，并且在变压器的输出绕组处测量输出信号，其中测量信号的电压可能非常低以致变压器在非线性区域中工作。该方法包括：对于调节信号，选择不同于第一频率（100）的第二频率，定义调节信号（110）的振幅值，并将调节信号以限定的幅度以第二频率提供给输入绕组使得变压器在其线性区域（120）中工作。

32. 发明申请

WO2011139210A1 GYRATORY CRUSHER COMPRISING A DUST SEAL AND METHOD OF FITTING 审中-公开
标题翻译：包括一个密封件和装配方法的打磨机
公开(公告)号：WO2011139210A1
公开(公告)日：2011-11-10
申请号：PCT/SE2011/050486
申请日：2011-04-20
申请人： SANDVIK INTELLECTUAL PROPERTY AB , JOHANSSON, Henrik
发明人： JOHANSSON, Henrik
IPC分类号： B02C2/06
CPC分类号： B02C2/06 , B02C2/00
摘要： A gyratory crusher comprises a crusher head (12) on which a first crushing shell is mounted; a frame (4) on which a second crushing shell is mounted and forms in conjunction with the first crushing shell a crushing aperture; a drive device adapted to rotating an eccentric to which the crusher head (12) is so connected as to be adapted to being caused, during rotation of the eccentric, to perform a gyratory movement for crushing of material which is introduced into the crushing aperture; and a dust seal (30) which is adapted to sealing a gap between the frame (4) and a fastening portion (37; 52) situated close to the crusher head (12) and which comprises a seal bellows (32) and a seal slide ring (34) which is connected sealingly to a lower portion of the seal bellows (32) and has a lower slide surface (42) adapted to sliding along, and to abutting sealingly, with a substantially vertical abutment pressure determined by the inherent weight of the seal slide ring (34) and by the influence of the seal bellows (32), against an upper slide surface (44) provided on the frame (4), with an upper portion (36) of the seal bellows (32) sealingly connected to said fastening portion (37; 52), so that rotation of the crusher head (12) causes rotation of the seal slide ring (34) about a substantially vertical axis of rotation.
摘要翻译：回转式破碎机包括：破碎机头（12），其上安装有第一破碎壳; 框架（4），其上安装有第二破碎壳并与第一破碎壳结合形成破碎孔; 驱动装置，其适于使所述破碎机头部（12）连接的偏心轮旋转，以适于在所述偏心件的旋转期间被引起，以执行用于破碎引入到所述破碎孔中的材料的回转运动; 以及防尘密封件（30），其适于密封所述框架（4）与位于所述破碎机头部（12）附近的紧固部分（37; 52）之间的间隙，并且包括密封波纹管（32）和密封件滑动环（34），其密封地连接到密封波纹管（32）的下部，并且具有下滑动表面（42），其适于沿着密封地以由固有重量确定的基本垂直的邻接压力滑动（34）的上部（36）与密封波纹管（32）的影响相对应的位于框架（4）上的上部滑动表面（44）上，密封地连接到所述紧固部分（37; 52），使得破碎机头部（12）的旋转导致密封滑动环（34）围绕基本垂直的旋转轴线旋转。

33. 发明申请

WO2011009941A1 PROBES FOR SPECIFIC ANALYSIS OF NUCLEIC ACIDS 审中-公开
标题翻译：具体分析核酸的探讨
公开(公告)号：WO2011009941A1
公开(公告)日：2011-01-27
申请号：PCT/EP2010/060715
申请日：2010-07-23
申请人： OLINK GENOMICS AB , ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , LANDEGREN, Ulf
发明人： ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , LANDEGREN, Ulf
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6855
摘要： The present invention provides a method for detecting or enriching for a target deoxyribonucleic acid (DNA) present in a nucleic acid sample, said method comprising: (a) fragmenting a nucleic acid sample to generate nucleic acid fragments including a target fragment containing said target DNA; (b) rendering said fragments, including said target fragment, at least partially single-stranded, wherein the single- stranded portion includes an end portion and wherein the length of said single- stranded portion is sufficient to allow hybridisation of at least part of the single- stranded portion of said target fragment to the probe of step (c); (c) contacting the at least partially single-stranded fragments of step (b) with oligonucleotides A and B of a single target-specific nucleic acid probe, wherein: (i) oligonucleotide A is a single- stranded oligonucleotide comprising at one end a first target-specific part comprising at least 10 nucleotides complementary in sequence to at least part of said single- stranded portion of said target fragment, and comprising at the other end a second non-target-specific part which comprises a nucleotide sequence complementary to at least a portion, including one end, of oligonucleotide B of the probe, and (ii) oligonucleotide B is a single-stranded oligonucleotide which may contain or carry at least one element for detection and/or enrichment of said target fragment, and of which at least a portion, including one end, is complementary in sequence to the second non-target-specific part of oligonucleotide A, such that said target fragment becomes annealed to said probe through hybridisation to the first target-specific part of oligonucleotide A resulting in only one target-specific probe-binding event per target fragment; (d) ligating oligonucleotide B of said probe to the part of the single- stranded portion of said target fragment which is hybridised to oligonucleotide A of said probe to produce a probe-target fragment hybrid; and (e) detecting or enriching for said probe-target fragment hybrid. Kits for use in the method of the invention are also provided.
摘要翻译：本发明提供了用于检测或富集存在于核酸样品中的靶脱氧核糖核酸（DNA）的方法，所述方法包括：（a）将核酸样品分段以产生包含含有所述靶DNA的靶片段的核酸片段 ; （b）使包含所述靶片段的所述片段至少部分单链，其中所述单链部分包含端部，并且其中所述单链部分的长度足以允许杂交的至少一部分所述靶片段的单链部分与步骤（c）的探针结合; （c）将步骤（b）的至少部分单链片段与单个靶特异性核酸探针的寡核苷酸A和B接触，其中：（i）寡核苷酸A是单链寡核苷酸，其包含一端第一靶特异性部分包含与所述靶片段的所述单链部分的至少部分序列至少互补的10个核苷酸，并且在另一端包含第二非靶特异性部分，其包含与探针的寡核苷酸B的至少一部分（包括一端），和（ii）寡核苷酸B是可以含有或携带至少一种用于检测和/或富集所述靶片段的元件的单链寡核苷酸，其中包括一端的至少一部分在序列上与寡核苷酸A的第二非目标特异性部分互补，使得所述靶片段通过杂交退火至所述探针到寡核苷酸A的第一靶特异性部分，导致每个靶片段仅一个靶特异性探针结合事件; （d）将所述探针的寡核苷酸B连接到与所述探针的寡核苷酸A杂交的所述靶片段的单链部分的部分，以产生探针 - 靶片段杂交体; 和（e）检测或富集所述探针 - 靶片段杂交体。还提供了用于本发明方法的试剂盒。

34. 发明申请

WO2009036791A1 INFLATABLE CURTAIN AIRBAG 审中-公开
标题翻译：充气窗帘安全气囊
公开(公告)号：WO2009036791A1
公开(公告)日：2009-03-26
申请号：PCT/EP2007/008243
申请日：2007-09-21
申请人： AUTOLIV DEVELOPMENT AB , JORLÖV, Andreas , JOHANSSON, Henrik , KJELL, Fredrik
发明人： JORLÖV, Andreas , JOHANSSON, Henrik , KJELL, Fredrik
IPC分类号： B60R21/231 , B60R21/20
CPC分类号： B60R21/201 , B60R21/232
摘要： Inflatable curtain airbag for a vehicle comprising an airbag body (1) rolled or folded to form a longitudinal airbag package with several attachment portions (6) and an indication element (2) for indicating a twisted attachment status of the airbag at the vehicle structure, wherein the indication element (2) is arranged in a releasable manner along at least parts of the longitudinal extension of the package.
摘要翻译：一种用于车辆的充气帘式气囊，其包括滚动或折叠以形成具有多个安装部分（6）的纵向安全气囊包装的气囊本体（1）和用于指示安全气囊在车辆结构处的扭转安装状态的指示元件（2）其中所述指示元件（2）沿着所述包装的纵向延伸部的至少一部分以可释放的方式布置。

35. 发明申请

WO2007030061A1 NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES 审中-公开
标题翻译：新西兰双倍体药物及其用于治疗CCR8介导性疾病的用途
公开(公告)号：WO2007030061A1
公开(公告)日：2007-03-15
申请号：PCT/SE2006/001012
申请日：2006-09-04
申请人： ASTRAZENECA AB , BÖRJESSON, Lena , CONNOLLY, Stephen , JOHANSSON, Henrik , KRISTOFFERSSON, Anna , LINNANEN, Tero , SHAMOVSKY, Igor , SKRINJAR, Marco
发明人： BÖRJESSON, Lena , CONNOLLY, Stephen , JOHANSSON, Henrik , KRISTOFFERSSON, Anna , LINNANEN, Tero , SHAMOVSKY, Igor , SKRINJAR, Marco
IPC分类号： C07D471/10 , A61K31/407 , A61K31/438 , A61P11/00 , A61P11/06 , C07D487/10
CPC分类号： C07D487/10 , C07D471/10
摘要： The invention provides compounds of general formula (I) wherein A, B, p, w, x, y, and z are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
摘要翻译：本发明提供了通式（I）的化合物，其中A，B，p，w，x，y和z如说明书中所定义，其制备方法，含有它们的药物组合物及其在治疗中的用途。

36. 发明申请

WO1983003005A1 PROCEDURE FOR ACCOMPLISHING LIQUID CONTACT AT SLOW LIQUID FLOW 审中-公开
标题翻译：缓慢液体接触液体流动的程序
公开(公告)号：WO1983003005A1
公开(公告)日：1983-09-01
申请号：PCT/FI1983000015
申请日：1983-02-18
申请人： KONE OY , JOHANSSON, Henrik
发明人： KONE OY
IPC分类号： G01N27/40
CPC分类号： G01N27/28 , G01N27/40
摘要： A procedure for establishing liquid contact at slow liquid flow for a measurement in which is measured the potential difference between two liquids, and a measuring pick-up manufactured by an according procedure, one of these liquids (the known liquid) being located in a reference channel (2) and the other (the liquid to be measured) being located in a sample liquid channel (10). With a view to producing such flow, the invention is mainly characterized in that in between the reference channel (2) and the sample liquid channel (10) is pressed a substance transforming to be fibrous on compression, such as Teflon (17).
摘要翻译：用于在缓慢的液体流动下建立液体接触以进行测量的程序，其中测量两种液体之间的电位差，以及通过相关程序制造的测量拾取器，这些液体（已知液体）中的一种位于参考通道（2）和另一个（待测量的液体）位于样品液体通道（10）中。为了产生这样的流动，本发明的主要特征在于，在参考通道（2）和样品液体通道（10）之间在压缩的状态下压制成纤维状的物质，例如特氟纶（17）。

37. 发明申请

WO2012056236A2 ANALYTICAL METHODS AND ARRAYS FOR USE IN THE SAME 审中-公开
标题翻译：分析方法和使用的阵列
公开(公告)号：WO2012056236A2
公开(公告)日：2012-05-03
申请号：PCT/GB2011/052082
申请日：2011-10-26
申请人： SENZAGEN AB , SMITH, Stephen Edward , LINDSTEDT, Malin , BORREBAECK, Carl A K , JOHANSSON, Henrik , ALBREKT, Ann-Sofie
发明人： LINDSTEDT, Malin , BORREBAECK, Carl A K , JOHANSSON, Henrik , ALBREKT, Ann-Sofie
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6876 , C12Q2600/148 , C12Q2600/158 , G01N33/5023 , G01N33/5044 , G01N33/5047
摘要： The present invention relates to an in vitro method for identifying agents capable of inducing sensitization of human skin and arrays and diagnostic kits for use in such methods. In particular, the methods include measurement of the expression of the biomarkers listed in Table 3A and/or 3B in MUTZ-3 cells exposed to a test agent.
摘要翻译：本发明涉及一种用于鉴定能够诱导人皮肤和阵列致敏的试剂的体外方法以及用于这些方法的诊断试剂盒。特别地，所述方法包括测量暴露于测试试剂的MUTZ-3细胞中表3A和/或3B中列出的生物标志物的表达。

38. 发明申请

WO2011067378A1 METHOD FOR AMPLIFICATION OF TARGET NUCLEIC ACID 审中-公开
标题翻译：放射性核酸的方法
公开(公告)号：WO2011067378A1
公开(公告)日：2011-06-09
申请号：PCT/EP2010/068837
申请日：2010-12-03
申请人： OLINK GENOMICS AB , ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , ROOS, Fredrik , FREDRIKSSON, Simon , NILSSON, Mats
发明人： ERICSSON, Olof , ISAKSSON, Magnus , JOHANSSON, Henrik , ROOS, Fredrik , FREDRIKSSON, Simon , NILSSON, Mats
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6837 , C12Q2565/519 , C12Q2531/125 , C12Q2563/131 , C12Q2525/161 , C12Q2521/501
摘要： The present invention provides a method for amplifying at least one target nucleic acid in a nucleic acid sample, comprising:(a) fragmenting the nucleic acid sample to create at least one target fragment comprising said target nucleic acid and comprising two probe-complementary portions, wherein at least one of said two probe-complementary portions is located at an end of the target fragment; (b) contacting said fragmented nucleic acid sample with at least one probe which is provided with an immobilisation moiety and optionally is immobilised on a solid phase by means of said moiety, and which comprises two target fragment-complementary portions which are complementary in sequence to the probe- complementary portions of the target fragment, wherein said portions of the probe may be adjacent, or separated by an intervening non-target fragment-complementary portion; (c) rendering the fragmented nucleic acid sample single- stranded, wherein the step may occur before, contemporaneously with or after step (b); (d) allowing the probe-complementary portions of the target fragment to hybridise with the target-fragment complementary portions of the probe; (e) if the probe provided in step (b) is not immobilised, immobilising the probe-target fragment hybrid on a solid phase by means of said immobilisation moiety; (f) separating non-immobilised nucleic acid fragments from the solid phase; (g) contacting the solid phase with a ligase to ligate, directly or indirectly, ligatable 5' and 3' ends of the target fragment whereby the target fragment is circularised, wherein where one of said probe-complementary portions of the target fragment is not located at an end of the target fragment, the ligatable end, other than that at which a probe-complementary portion is located, is created by the action of a flap endonuclease or an exonuclease; and (h) amplifying said circularised target fragment. Kits for use in the method of the invention are also provided.
摘要翻译：本发明提供了用于扩增核酸样品中的至少一种靶核酸的方法，其包括：（a）使核酸样品片段化以产生至少一个包含所述靶核酸的靶片段并且包含两个探针互补部分，其中所述两个探针互补部分中的至少一个位于所述靶片段的末端; （b）使所述片段化的核酸样品与至少一个具有固定部分的探针接触，并且任选地通过所述部分固定在固相上，并且其包含两个靶序列互补部分，其与序列互补所述靶片段的探针互补部分，其中所述探针的所述部分可以相邻，或由介入的非靶片段互补部分分开; （c）使所述片段化的核酸样品单链，其中所述步骤可以在步骤（b）之前或之后发生; （d）允许靶片段的探针互补部分与探针的靶 - 片段互补部分杂交; （e）如果步骤（b）中提供的探针未被固定，则通过所述固定部分将探针 - 靶片段杂交体固定在固相上; （f）从固相中分离未固定的核酸片段; （g）使固相与连接酶接触直接或间接连接目标片段的5'和3'末端，由此靶片段是环化的，其中靶片段的所述探针互补部分之一不是位于靶片段的末端，通过翼片内切核酸酶或外切核酸酶的作用产生除了探针互补部分所位于之外的可连接末端; 和（h）扩增所述环化的靶片段。还提供了用于本发明方法的试剂盒。

39. 发明申请

WO2010126446A1 DEMOUNTABLE FLOORING 审中-公开
标题翻译：不可接受的地板
公开(公告)号：WO2010126446A1
公开(公告)日：2010-11-04
申请号：PCT/SE2010/050475
申请日：2010-04-29
申请人： MON.ZON DEVELOPMENT AB , JOHANSSON, Henrik , CARLBOM, Lars
发明人： JOHANSSON, Henrik , CARLBOM, Lars
IPC分类号： E04H3/24 , E04F15/024
CPC分类号： E04H3/28 , E04G1/151 , E04H3/24
摘要： An edge profile (1) for connection of a decking member (2) to a supporting frame in a demountable flooring construction is provided. Said edge profile (1) has a top end, a bottom end and two side walls between the top end and the bottom end. A first projection unit (3) extends towards the bottom end of said edge profile (1) and is positioned at one of said side walls of said edge profile (1). Said edge profile (1) further comprises at least one second projection unit (4) extending towards the bottom end of said edge profile (1) and positioned at a distance from said first projection unit (3). The first and second projection units define a substantially U-shaped cavity (5) there between.
摘要翻译：提供了一种用于在可拆卸的地板结构中将甲板构件（2）连接到支撑框架的边缘轮廓（1）。所述边缘轮廓（1）具有顶端，底端和在顶端和底端之间的两个侧壁。第一投影单元（3）朝着所述边缘轮廓（1）的底端延伸并且被定位在所述边缘轮廓（1）的所述侧壁之一处。所述边缘轮廓（1）还包括朝向所述边缘轮廓（1）的底端延伸并且定位在离所述第一投影单元（3）一定距离处的至少一个第二投影单元（4）。第一和第二投影单元在其间限定基本上为U形的空腔（5）。

40. 发明申请

WO2008063113A8 CELL -PENETRATING PEPTIDES AND CONSTRUCTS CONTAINING THEM CONSISTING 15-25 AMINO ACIDS OF TUMOR SUPRESSOR PROTEIN P14ARF OR P19ARF 审中-公开
标题翻译：细胞 - 渗透肽和包含它们的构建物，其包含15-25个氨基酸的肿瘤抑制蛋白P14ARF或P19ARF
公开(公告)号：WO2008063113A8
公开(公告)日：2009-07-23
申请号：PCT/SE2007001017
申请日：2007-11-19
申请人： CEPEP III AB , LANGEL UELO , JOHANSSON HENRIK , EL-ANDALOUSSI SAMIR
发明人： LANGEL UELO , JOHANSSON HENRIK , EL-ANDALOUSSI SAMIR
IPC分类号： C07K14/47 , A61K38/17 , C12N15/87
CPC分类号： C07K14/4703 , A61K38/00 , A61K47/64 , C12N15/87
摘要： A cell-penetrating peptide or a construct comprising such a peptide of 15 to 25 amino acids comprising at least amino acids 1 - 14 of a mature mammalian tumor suppressor protein ARF or a scrambled or partially inverted sequence thereof, such as the human p14ARF protein SEQ ID NO:2, and the partially inverted sequence thereof SEQ ID NO: 1 optionally linked to one or more of a cargo, such as an anti-cancer drug, a detection marker, a cell-homing peptide, such as a tumor-homing peptide, a receptor ligand, a linker, and a peptide spacer comprising a selective protease cleavage site coupled to an inactivating peptide, is disclosed. The cell-penetrating peptides of the invention derived from ARF can either be biologically inert or have biological activity in themselves. Further, a method of delivering a cargo into a target cell in vivo or in vitro, is described.
摘要翻译：一种细胞穿透肽或包含这样的15至25个氨基酸的肽的构建体，其至少包含成熟哺乳动物肿瘤抑制蛋白ARF的氨基酸1-14或其加扰或部分倒置的序列，例如人p14ARF蛋白SEQ SEQ ID NO：1的部分倒置的序列，任选地与一种或多种货物如抗癌药物，检测标志物，细胞归巢肽如肿瘤归巢肽，受体配体，接头和包含与灭活肽偶联的选择性蛋白酶切割位点的肽间隔基。衍生自ARF的本发明的细胞穿透肽本身可以是生物惰性的或具有生物活性。此外，描述了在体内或体外将货物递送到靶细胞中的方法。

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