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    • 31. 发明申请
    • Advanced Convergence for Multiple Iterative Algorithm
    • 多重迭代算法的高级收敛
    • US20080273656A1
    • 2008-11-06
    • US12096911
    • 2006-12-04
    • Andy ZieglerMichael Grass
    • Andy ZieglerMichael Grass
    • A61B6/00G06K9/00
    • G06T11/005G06T2211/424
    • Iterative methods for reconstructing of three-dimensional images based on projection data signals obtained by a computer tomography system often result in wrong absorption coefficients in particular for regions including a hollow space of an object under examination. Furthermore iterative methods show a slow convergence for calculating such absorption coefficients. According to embodiments of the present invention there is provided a method for an advanced reconstruction of three-dimensional images based on modified projection data signals. The modification includes an addition of a constant absorption value to the measured projection data. Advantageously the constant absorption value is an absorption line integral through a virtual body having the spatial constant absorption coefficient of water. The virtual body preferably has a volume which is slightly bigger than the object of interest.
    • 基于由计算机断层摄影系统获得的投影数据信号重建三维图像的迭代方法通常导致错误的吸收系数,特别是对于包括被检查物体的中空空间的区域。 此外,迭代方法显示计算这种吸收系数的缓慢收敛。 根据本发明的实施例,提供了一种基于经修改的投影数据信号对三维图像进行高级重建的方法。 修改包括对所测量的投影数据添加恒定的吸收值。 有利地,恒定吸收值是通过具有水的空间常数吸收系数的虚拟体积分的吸收线。 虚拟体优选地具有比感兴趣对象略大的体积。
    • 32. 发明申请
    • Method and Device for the Iterative Reconstruction of Cardiac Images
    • 心脏图像迭代重建方法与装置
    • US20080253502A1
    • 2008-10-16
    • US11908415
    • 2006-03-09
    • Andy ZieglerMichael GrassThomas Koehler
    • Andy ZieglerMichael GrassThomas Koehler
    • H05G1/60
    • G06T11/006A61B6/027G06T2211/424
    • The invention relates to a method and a device for the iterative reconstruction of cross-sectional images of the heart (7) of a patient based on projections (P1, . . . P5) from different directions which are for example generated with a helical cone-beam CT scanner. A cardiac weight function (f) quantifies how near the projections (P1, . . . ) are to a given observation phase (To) of the heart cycle based on simultaneously recorded electrocardiographic signals (ECG). The whole set of projections (P1, . . . ) is divided into subsets (S1, . . . ) which each contain only projections corresponding to a similar cardiac weight (f), and an iterative reconstruction algorithm like ART uses in one update or iteration step all projections of such a subset (S1, . . . ) simultaneous].
    • 本发明涉及一种用于基于来自不同方向的投影(P 1,...,P 5)迭代重建病人心脏(7)的横截面图像的方法和装置,其例如用 螺旋锥束CT扫描仪。 心脏重量函数(f)基于同时记录的心电图信号(ECG)量化投影(P 1,...)附近到心脏周期的给定观察阶段(To)的距离。 整个投影组(P 1,...)被划分成子集(S 1,...),每个子集仅包含对应于类似心脏重量(f)的投影,并且像ART这样的迭代重建算法在一个 更新或迭代步骤同步所有这样的子集(S 1,...)的投影。
    • 35. 发明授权
    • Method for reconstructing a fluorescent image of the interior of a turbid medium and device for imaging the interior of a turbid medium
    • 用于重建浑浊介质内部的荧光图像的方法和用于对浑浊介质的内部进行成像的装置
    • US08520921B2
    • 2013-08-27
    • US12933887
    • 2009-03-20
    • Ronny ZieglerAndy ZieglerTim Nielsen
    • Ronny ZieglerAndy ZieglerTim Nielsen
    • G06K9/00
    • A61B5/4312A61B5/0091G01N21/4795G01N21/6428
    • A method for reconstructing a fluorescence image of the interior of a turbid medium is provided. The method comprises the step: accommodating a turbid medium (1) to which a fluorescent contrast agent has been administered in a measurement volume (4). The fluorescent contrast agent is capable of emitting light in a first range of wavelengths upon irradiation with light. The method further comprises: performing attenuation measurements at a plurality of different wavelengths (λi, . . . , λk) by subsequently irradiating the turbid medium (1) with light from a plurality of different source positions and detecting light emanating from the turbid medium (1) in a plurality of detection positions for each source position; reconstructing absorption properties (μa(r, λ) as a function of the position in the interior of the turbid medium (1) for the plurality of different wavelengths from the attenuation measurements; calculating absorption properties as a function of the position in the interior of the turbid medium (1) for wavelengths of the first range of wavelengths; performing a fluorescence measurement by subsequently irradiating the turbid medium (1) with light causing the fluorescent contrast agent to emit light in the first range of wavelengths from the plurality of source positions and detecting the light emanating from the fluorescent contrast agent in the plurality of detection positions for each source position; and reconstructing a fluorescence image of the spatial distribution of the fluorescent contrast agent in the interior of the turbid medium (1) from the fluorescence measurement using the calculated absorption properties.
    • 提供了一种用于重建浑浊介质内部的荧光图像的方法。 该方法包括以下步骤:在测量体积(4)中容纳已投与荧光造影剂的混浊介质(1)。 荧光造影剂能够在照射光时在第一波长范围内发光。 该方法还包括:通过随后用来自多个不同源位置的光照射浑浊介质(1)并检测从浑浊介质发出的光,以多个不同波长(兰德,兰布克)进行衰减测量 1)在每个源位置的多个检测位置; 根据衰减测量重建吸收性质(mu(r,λ))作为多个不同波长的混浊介质(1)内部的位置的函数;计算作为内部位置的函数的吸收特性 用于波长第一波长范围的混浊介质(1);通过随后用引起荧光对比剂的光在多个源位置发射第一波长范围内的光来照射浑浊介质来进行荧光测量 以及在每个源位置的多个检测位置中检测从荧光对比剂发出的光;以及从所述荧光测量中使用所述荧光测量重建所述浑浊介质(1)内的荧光对比剂的空间分布的荧光图像,使用 计算吸收性能。
    • 37. 发明授权
    • Advanced convergence for multiple iterative algorithm
    • 多重迭代算法的高级收敛
    • US07961839B2
    • 2011-06-14
    • US12096911
    • 2006-12-04
    • Andy ZieglerMichael Grass
    • Andy ZieglerMichael Grass
    • A61B6/00
    • G06T11/005G06T2211/424
    • Iterative methods for reconstructing of three-dimensional images based on projection data signals obtained by a computer tomography system often result in wrong absorption coefficients in particular for regions including a hollow space of an object under examination. Furthermore iterative methods show a slow convergence for calculating such absorption coefficients. According to embodiments of the present invention there is provided a method for an advanced reconstruction of three-dimensional images based on modified projection data signals. The modification includes an addition of a constant absorption value to the measured projection data. Advantageously the constant absorption value is an absorption line integral through a virtual body having the spatial constant absorption coefficient of water. The virtual body preferably has a volume which is slightly bigger than the object of interest.
    • 基于由计算机断层摄影系统获得的投影数据信号重建三维图像的迭代方法通常导致错误的吸收系数,特别是对于包括被检查物体的中空空间的区域。 此外,迭代方法显示计算这种吸收系数的缓慢收敛。 根据本发明的实施例,提供了一种基于经修改的投影数据信号对三维图像进行高级重建的方法。 修改包括对所测量的投影数据添加恒定的吸收值。 有利地,恒定吸收值是通过具有水的空间常数吸收系数的虚拟体积分的吸收线。 虚拟体优选地具有比感兴趣对象略大的体积。
    • 38. 发明申请
    • PROJECTION SYSTEM FOR PRODUCING ATTENUATION COMPONENTS
    • 用于生产衰减组件的投影系统
    • US20100104161A1
    • 2010-04-29
    • US12529715
    • 2008-03-03
    • Andy ZieglerEwald RoesslRoland Proksa
    • Andy ZieglerEwald RoesslRoland Proksa
    • G06T5/00
    • G06T11/005G06T5/002G06T5/20G06T2207/10081G06T2207/30004
    • The invention relates to a projection system for producing attenuation components of projection data of a region of interest. The projection system comprises a projection data providing unit (1, 2, 6, 7, 8) for providing energy-dependent projection data of the region of interest. The projection system further comprises a calculation unit (12) for calculating different attenuation components generated by different attenuation effects from the energy-dependent projection data, wherein the different attenuation components contribute to the projection data and a transformation unit (13) for transforming the attenuation components such that a correlation of the attenuations components is reduced. The invention relates further to a corresponding projection method and a corresponding computer program.
    • 本发明涉及用于产生感兴趣区域的投影数据的衰减分量的投影系统。 投影系统包括用于提供感兴趣区域的与能量相关的投影数据的投影数据提供单元(1,2,6,7,8)。 投影系统还包括计算单元(12),用于根据能量相关投影数据计算由不同衰减效应产生的不同衰减分量,其中不同的衰减分量有助于投影数据;以及变换单元(13),用于变换衰减 使得衰减分量的相关性降低的组件。 本发明进一步涉及相应的投影方法和相应的计算机程序。
    • 40. 发明申请
    • METHOD FOR COMPUTER TOMOGRAPHY, AND COMPUTER TOMOGRAPH
    • 计算机图形学和计算机图形学的方法
    • US20090310737A1
    • 2009-12-17
    • US11721543
    • 2005-12-13
    • Peter ForthmannThomas KoehlerRobert ManzkeMichael GrassAndy Ziegler
    • Peter ForthmannThomas KoehlerRobert ManzkeMichael GrassAndy Ziegler
    • A61B6/00
    • A61B6/541A61B6/027A61B6/032A61B6/4085A61B6/503
    • According to the invention, there is provided a method of recording images of the heart in computer tomography, in which, in order to prevent movement artifacts, the images are reconstructed on the basis of similar movement states of the heart and different radiation intensities are used for different movement states. Also provided is a computer tomograph for recording images of the heart in computer tomography by means of time windows which exhibit similar movement states of the heart in order to prevent movement artifacts, said computer tomograph comprising a control device which controls a radiation source with different radiation intensities for different movement states. Furthermore provided is a computer program for a computer tomograph for recording images of the heart in computer tomography by means of time windows which exhibit similar movement states of the heart in order to prevent movement artifacts, and for controlling a radiation source with different radiation intensities for different movement states.
    • 根据本发明,提供了一种在计算机断层摄影中记录心脏图像的方法,其中为了防止运动伪像,基于心脏的相似运动状态重建图像,并且使用不同的辐射强度 对于不同的运动状态。 还提供了一种用于在计算机断层摄影中记录心脏图像的计算机断层摄影装置,其通过显示相似的心脏运动状态以防止运动伪像的时间窗口,所述计算机断层摄影机包括控制具有不同辐射的辐射源的控制装置 不同运动状态的强度。 此外还提供了一种计算机断层摄影机的计算机程序,用于通过时间窗口在计算机断层摄影中记录心脏的图像,所述时间窗口表现出相似的心脏运动状态以便防止运动伪像,并且用于控制具有不同辐射强度的辐射源 不同的运动状态。