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31. 发明申请

WO2017214434A1 DRUG-ELUTING STENT FORMED FROM A DEFORMABLE HOLLOW STRUT FOR A CUSTOMIZABLE ELUTION RATE 审中-公开
标题翻译：用于可定制选率的由可变形空心支架形成的药物支架
公开(公告)号：WO2017214434A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036607
申请日：2017-06-08
申请人： MEDTRONIC VASCULAR INC.
发明人： CIAN, Ryan , HOBBINS, David , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , O'DONOVAN, Conor
IPC分类号： A61F2/915
摘要： Methods and apparatus are disclosed for customizing an elution rate of a stent. The stent includes a hollow strut that forms the stent, the hollow strut defining a lumenal space, a drug formulation disposed within the lumenal space of the hollow strut, and at least one side port for eluting the drug formulation in vivo . When the stent is in the radially expanded configuration the hollow strut is deformable from a first configuration that has a first elution rate for the drug formulation to a second configuration that has a second elution rate for the drug formulation. The second elution rate is faster than the first elution rate. The hollow strut deforms from the first configuration to the second configuration upon application of an applied pressure above a predetermined threshold.
摘要翻译：公开了用于定制支架的洗脱速率的方法和设备。支架包括形成支架的中空支柱，中空支柱限定内腔空间，布置在中空支柱的腔空间内的药物制剂以及用于在体内洗脱药物制剂的至少一个侧端口， I>。当支架处于径向扩张构型时，中空支柱可从具有药物制剂的第一洗脱速率的第一构型变形成具有药物制剂的第二洗脱速率的第二构型。第二次洗脱速率比第一次洗脱速率快。在施加高于预定阈值的施加压力时，中空支柱从第一构型变形为第二构型。

32. 发明申请

WO2017214432A1 CUSTOMIZING THE ELUTION PROFILE OF A STENT 审中-公开
标题翻译：定制一个支架的选择简介
公开(公告)号：WO2017214432A1
公开(公告)日：2017-12-14
申请号：PCT/US2017/036604
申请日：2017-06-08
申请人： MEDTRONIC VASCULAR INC.
发明人： HOBBINS, David , O'DONOVAN, Conor , WOLLEY, Lana , NOLAN, Shane , SAYERS, Michael , KEANE, Eamon , DOWLING, Brian , COPE, Jonathan , ANDERSON, Marc , EGERTER, Risa
IPC分类号： A61F2/88 , A61F2/915
摘要： Methods and apparatus are disclosed for customizing an elution profile of a stent after manufacture of the stent has been completed. The stent includes a plurality of side ports for eluting a drug formulation within a lumenal space of a hollow strut that forms the stent. An effective diameter of at least one side port of the plurality of side ports of the stent is modified in order to customize an elution profile of the stent. In an embodiment hereof, the plurality of side ports are completely blocked or plugged with a filler material during the manufacture of the stent and at least a portion of the filler material is removed to increase an effective diameter of at least one side port of the plurality of side ports of the stent in order to customize an elution profile of the stent. In another embodiment hereof, the plurality of side ports are open following the manufacture of the stent and at least one side port of the plurality of side ports of the stent is at least partially filled with a filler material to decrease the effective diameter of the at least one side port in order to customize an elution profile of the stent. In another embodiment hereof, the stent is soaked within a liquid to remove at least a portion of the drug formulation from the lumenal space of the hollow strut to thereby customize an elution profile of the stent.
摘要翻译：公开了用于在支架制造完成后定制支架的洗脱轮廓的方法和设备。该支架包括多个侧孔，用于在形成支架的中空支柱的内腔空间内洗脱药物制剂。对支架的多个侧孔中的至少一个侧孔的有效直径进行修改以便定制支架的洗脱轮廓。在本发明的一个实施例中，在制造支架期间，多个侧孔被填充材料完全堵塞或堵塞，并且至少一部分填充材料被去除以增加多个侧孔中的至少一个侧孔的有效直径为了定制支架的洗脱曲线，支架侧孔的尺寸。在本发明的另一个实施例中，在制造支架之后，多个侧端口是开放的，并且支架的多个侧端口中的至少一个侧端口至少部分地填充有填充材料，以减小支架的有效直径至少一个侧端口以定制支架的洗脱轮廓。在本发明的另一个实施方案中，将支架浸入液体中以从中空支撑物的腔空间去除至少一部分药物制剂，从而定制支架的洗脱轮廓。

33. 发明申请

WO2017180398A1 GUIDE EXTENSION CATHETER WITH HELICALLY-SHAPED ENTRY PORT 审中-公开
标题翻译：带有螺旋形入口端口的导向扩张导管
公开(公告)号：WO2017180398A1
公开(公告)日：2017-10-19
申请号：PCT/US2017/026213
申请日：2017-04-05
申请人： MEDTRONIC VASCULAR INC.
发明人： CONNOLLY, Colm , GRIFFIN, Patrick
IPC分类号： A61M25/01 , A61M25/06
CPC分类号： A61M25/0102 , A61M25/0052 , A61M25/0662 , A61M25/09 , A61M2025/0004 , A61M2025/0681 , A61M2025/09191 , A61M2205/0266
摘要： A guide extension catheter includes a push member and a distal shaft coupled to and extending distally from the push member. The distal shaft includes a shaft wall and a passageway. The shaft wall includes a helically-shaped proximal end and a distal end. The helically-shaped proximal end coils helically about a first central longitudinal axis of the passageway of the distal shaft. The helically-shaped proximal end of the shaft wall defines a helically-shaped entry port of the distal shaft. The distal shaft may include a helically-shaped collar coupled to the helically-shaped proximal end of the distal shaft, the collar defining the helically-shaped entry port of the distal shaft.
摘要翻译：引导延伸导管包括推动构件和联接到推动构件并从推动构件向远侧延伸的远侧轴。远侧轴包括轴壁和通道。轴壁包括螺旋形近端和远端。螺旋形近端螺旋形地缠绕在远端轴的通道的第一中心纵向轴线周围。轴壁的螺旋形近端限定了远侧轴的螺旋形入口。远侧轴可包括联接到远侧轴的螺旋形近侧端部的螺旋形轴环，轴环限定远侧轴的螺旋形进入端口。

34. 发明申请

WO2017100472A1 CATHETER WITH A LUMEN SHAPED AS AN IDENTIFICATION SYMBOL 审中-公开
标题翻译：带有流明标识作为标识符号的导管
公开(公告)号：WO2017100472A1
公开(公告)日：2017-06-15
申请号：PCT/US2016/065655
申请日：2016-12-08
申请人： MEDTRONIC VASCULAR INC.
发明人： TUOHY, John , WARD, Sean
IPC分类号： A61M25/01 , A61M25/00 , A61B90/96 , A61B90/00
CPC分类号： A61M25/0023 , A61B90/39 , A61B90/96 , A61B2090/3933 , A61B2090/3966 , A61M25/0009 , A61M25/0108 , A61M31/005 , A61M2205/32 , A61M2205/6072 , A61M2207/00 , B29C59/16 , B29L2031/7543
摘要： A catheter (100) includes a catheter shaft having a shaft wall and a lumen (135) extending longitudinally within the shaft wall. The lumen is bounded in radially outward and radially inward directions. The lumen includes a feed portion (138) and an identification symbol (140) fluidly connected to the feed portion. The lumen is configured to receive a contrast media. The lumen may be formed by a channel (130) formed in an outer surface of a first shaft (120) of the catheter shaft, and a covering (115) disposed around the outer surface of the first shaft to cover the channel.
摘要翻译：导管（100）包括具有轴壁和在轴壁内纵向延伸的内腔（135）的导管轴。内腔沿径向向外和径向向内方向界定。内腔包括馈送部分（138）和流体连接到馈送部分的识别符号（140）。内腔配置成接收造影剂。内腔可以由形成在导管轴的第一轴（120）的外表面中的通道（130）和围绕第一轴的外表面布置以覆盖通道的覆盖物（115）形成。 p>

35. 发明申请

WO2014152038A2 HELICAL PUSH WIRE ELECTRODE 审中-公开
标题翻译：螺旋推线电极
公开(公告)号：WO2014152038A2
公开(公告)日：2014-09-25
申请号：PCT/US2014/026854
申请日：2014-03-13
申请人： MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
发明人： KU, Vincent , WU, Andrew
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/18 , A61B2018/00083 , A61B2018/00214 , A61B2018/00267 , A61B2018/00404 , A61B2018/00511 , A61B2018/00577 , A61B2018/1435 , A61B2018/144
摘要： Helical push wire electrodes are provided. The electrodes may create a continuous helical lesion. One or more electrodes may wind around a support section and create a set of helixes having fixed ends and hitches. Pushing or pulling an end of the electrode transforms the electrodes between a delivery configuration and a deployed configuration such that the set of helixes expand or contract axially. Different portions of the electrodes may be surrounded by sleeves. The sleeves may regulate how the wires transform and provide insulation. Various insulation configurations of the electrodes may provide creations of discrete lesions, efficient energy delivery and reduced power consumption.
摘要翻译：
提供了螺旋推线电极。电极可能会产生连续的螺旋病变。一个或多个电极可缠绕支撑部分并形成一组具有固定端部和挂钩的螺旋。推动或拉动电极的一端将电极在输送构造和展开构造之间转换，使得该组螺旋轴向地膨胀或收缩。电极的不同部分可以被套筒包围。套管可以调节导线如何变形并提供绝缘。电极的各种绝缘配置可以提供不连续损伤的产生，有效的能量输送和降低的功耗。

36. 发明申请

WO2014145146A1 CONTROLLED NEUROMODULATION SYSTEMS AND METHODS OF USE 审中-公开
标题翻译：控制神经网络系统及其使用方法
公开(公告)号：WO2014145146A1
公开(公告)日：2014-09-18
申请号：PCT/US2014/029860
申请日：2014-03-14
申请人： MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.
发明人： SHAH, Jignesh
IPC分类号： A61N1/05 , A61N1/36 , A61B18/14 , A61B18/00
CPC分类号： A61B18/1206 , A61B8/445 , A61B18/1492 , A61B2018/00011 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00904 , A61B2090/061 , A61B2090/3784 , A61N1/0551 , A61N1/3605 , A61N1/36167
摘要： The present disclosure relates to devices, systems and methods for positioning a neuromodulation device at a treatment site and evaluating the effects of therapeutic energy delivery applied to tissue in a patient. Before, during and/or after therapeutic energy delivery, a system can monitor parameters or values relevant to efficacious neuromodulation by emitting and detecting diagnostic energy at the treatment site. Feedback provided to an operator is based on the monitored values and relates to a relative position of the treatment device at the treatment site, as well as assessment of the likelihood that a completed treatment was technically successful.
摘要翻译：本公开涉及用于在治疗部位定位神经调节装置的装置，系统和方法，以及评估施加于患者组织的治疗能量递送的影响。在治疗能量输送之前，期间和/或之后，系统可以通过在治疗部位发射和检测诊断能量来监测与有效神经调节相关的参数或值。提供给操作员的反馈是基于监测值，并涉及治疗装置在治疗部位的相对位置，以及评估完成治疗在技术上成功的可能性。

37. 发明申请

WO2012166738A1 EASILY SERVICEABLE AND REMOVABLE SELF-ADJUDTING KNIFE ARM AND HEAD ASSEMBLY FOR A SICKLE 审中-公开
标题翻译：易于维修和可拆卸的自我调整刀具和头盔组件
公开(公告)号：WO2012166738A1
公开(公告)日：2012-12-06
申请号：PCT/US2012/039869
申请日：2012-05-29
申请人： CNH AMERICA LLC , COOK, Joel, T. , BICH, Gary, L. , DECHRISTOPHER, David, M. , WILBERT, Andrew, R. , NOLL, Blaine, R. , ROBERTS, Craig, D.
发明人： COOK, Joel, T. , BICH, Gary, L. , DECHRISTOPHER, David, M. , WILBERT, Andrew, R. , NOLL, Blaine, R. , ROBERTS, Craig, D.
IPC分类号： A01D34/14
CPC分类号： A01D34/14 , A01D34/145 , A01D34/33
摘要： The knife head (64) mounts to the sickle (30) to hold a plurality of knife sections (60) thereon while allowing removal of the knife sections (60) individually without major disassembly for ease of in field repair and replacement. A knife pin (84) of the knife head (64) connects to a knife arm (66) driven by the sickle drive mechanism (62A, 62B) and is removable from above also without major disassembly. The knife pin (84) connection provides a vertical self adjustment capability to accommodate sickle (30) wear and vertical misalignment between the sickle (30) and drive (62A, 62B). And the knife arm (66) is streamlined for cut plant material flow thereabout and is also adapted for ease of removal and field repair.
摘要翻译：刀头（64）安装到镰刀（30）上以在其上保持多个刀部（60），同时允许单独地移除刀部（60）而无需大的拆卸，便于现场维修和更换。刀头（64）的刀销（84）连接到由镰刀驱动机构（62A，62B）驱动的刀臂（66），并且也可从上方移除，也不会大幅度拆卸。刀销（84）连接提供垂直自调节能力，以容纳镰刀（30）和驱动器（62A，62B）之间的镰刀（30）磨损和垂直未对准。并且刀臂（66）是流线型的，用于在其周围切割植物材料流，并且还适于易于去除和现场修复。

38. 发明申请

WO2023021443A1 HEAT EXCHANGER FOR A CHARGING INLET ASSEMBLY 审中-公开
公开(公告)号：WO2023021443A1
公开(公告)日：2023-02-23
申请号：PCT/IB2022/057718
申请日：2022-08-17
申请人： RHODES, Clara M , TE CONNECTIVITY SOLUTIONS GMBH
发明人： MYER, Nathan , PETERSON, Kevin John , HITCHCOCK, Matthew , DE CHAZAL, Aaron James
IPC分类号： B60L53/10 , B60L53/16 , B60L53/302
摘要： A DC charging module (104) for a charging inlet assembly (100) includes a module housing (160) extending between a front (170) and a rear (172). The module housing has an inner chamber (162) between the front and the rear. The DC charging module includes a terminal having a mating pin (200) at a front of the terminal and a cable connector (202) at a rear of the terminal. The cable connector is located in the inner chamber of the module housing. The mating pin extends forward of the module housing into the charging inlet assembly for mating with a charging connector coupled to the charging inlet assembly. The DC charging module includes a power cable (128)extending into the inner chamber of the module housing to electrically connect to the cable connector of the terminal. The DC charging module includes a heat exchanger(300) received in the inner chamber of the module housing. The heat exchanger is thermally coupled to the cable connector of the terminal. The heat exchanger includes a coolant channel (302) for coolant flow through the heat exchanger for actively cooling the terminal.

39. 发明申请

WO2023012761A1 MODULAR CABLE HOLDING SYSTEM AND DEVICE 审中-公开
公开(公告)号：WO2023012761A1
公开(公告)日：2023-02-09
申请号：PCT/IB2022/057340
申请日：2022-08-05
申请人： ONDO, Mark Andrew , TE CONNECTIVITY SERVICES GMBH
发明人： ROPER, Craig , CRUZ, Isaac , TROUTMAN, Todd Mathew
IPC分类号： H02G1/00 , H01R43/28
摘要： A cable holding system for positioning a cable (10) relative to a cable processing machine (400) comprises a cable holding device (100) for selectively clamping onto a cable (10)to be processed, and a receiver (200). The receiver (200) includes an opening (220) for selectively receiving the cable holding device (100) in a predetermined orientation, and amounting base (214) for fixing the location of the receiver (200) relative to the cable processing machine (400).

40. 发明申请

WO2022259207A2 TERMINAL APPLICATOR TO CASSETTE MOUNTING APPARATUS 审中-公开
公开(公告)号：WO2022259207A2
公开(公告)日：2022-12-15
申请号：PCT/IB2022/055389
申请日：2022-06-09
申请人： STULL, Daivd Michael , TE CONNECTIVITY SERVICES GMBH
发明人： HOUSER, Matthew Steven , DEPASQUALE, Jack
IPC分类号： H01R43/055 , H01R43/0428
摘要： A system (10) for mounting an electrical terminal applicator (12) to a cassette (14,180)containing a plurality of terminals is provided. The system (10) includes a support plate (110) for fixedly attaching to the applicator (12), and a yoke (150) releasably attached to the support plate.The yoke (150) and support plate (110) define an attachment therebetween providing at least one degree of freedom of motion of the support plate relative to the yoke in an attached state. The yoke (150) is further configured to be movably mounted to the cassette (14) with at least one additional degree of freedom of motion.

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