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21. 发明专利

JPS57500264A JPS57500264A - 失效
标题翻译：空值
公开(公告)号：JPS57500264A
公开(公告)日：1982-02-12
申请号：JP50085481
申请日：1981-03-06
IPC分类号： B01D15/08 , G01N30/60
CPC分类号： G01N30/6065 , G01N30/60 , G01N30/6043 , G01N30/6047 , G01N30/466

22. 发明申请

WO2009127359A8 METHOD FOR ISOLATING POLYPEPTIDES 审中-公开
标题翻译：式分离方法的多肽
公开(公告)号：WO2009127359A8
公开(公告)日：2010-01-21
申请号：PCT/EP2009002637
申请日：2009-04-09
申请人： QIAGEN GMBH , FECKLER CHRISTIAN
发明人： FECKLER CHRISTIAN
IPC分类号： B01J20/00 , C07K1/16 , G01N30/00
CPC分类号： C07K1/16 , B01D15/36 , B01D15/3804 , B01J20/20 , G01N30/6065
摘要： The present invention relates to a method for isolating and/or purifying at least one polypeptide from a sample comprising polypeptides, characterized in that the sample is brought in contact with a boron carbide carrier material at a ph-value allowing the binding of the polypeptide to the boron carbide carrier material. An associated isolation can be used for example to remove polypeptides from a sample or for purifying polypeptides and/or for concentrating them. The invention further relates to a matrix comprising a boron carbide carrier material for purifying polypeptides.
摘要翻译：本发明涉及一种用于从含多肽的样品，其特征在于，所述样品是在多肽的结合的pH值使其与碳化硼载体材料相接触的隔离和/或至少一种多肽纯化的方法碳化硼支撑材料允许的。相应的绝缘，可以使用，例如，从样品中除去多肽或纯化然而，多肽和/或浓缩。另外，矩阵包括公开了一种用于根据本发明的多肽的纯化碳化硼载体材料。

23. 发明申请

WO2009073270A1 DIFFERENTIAL ACCELERATION CHROMATOGRAPHY 审中-公开
标题翻译：差异加速色谱法
公开(公告)号：WO2009073270A1
公开(公告)日：2009-06-11
申请号：PCT/US2008/078218
申请日：2008-09-30
申请人： SERVICES PETROLIERS SCHLUMBERGER , SCHLUMBERGER CANADA LIMITED , SCHLUMBERGER HOLDINGS LIMITED , SCHLUMBERGER TECHNOLOGY B.V. , PRAD RESEARCH AND DEVELOPMENT LTD , SHAH, Jagdish , STEINECKER, William, H. , ZHDANEEV, Oleg , LAMBERTUS, Gordon, R. , CHEN, Hua
发明人： STEINECKER, William, H. , ZHDANEEV, Oleg , LAMBERTUS, Gordon, R. , CHEN, Hua
IPC分类号： B01D15/22 , G01N30/60
CPC分类号： B01D15/22 , G01N30/32 , G01N30/52 , G01N30/54 , G01N30/6065 , G01N2030/324 , G01N2030/524
摘要： Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.
摘要翻译：描述了通过新技术改进色谱分离的方法和相关系统。分离的改进主要是由于提供了被分离的部件的差速加速。描述了用于提供差速加速度的各种系统和方法，其包括：将塔的横截面增加到塔出口，改变柱内的固定相的厚度或其它组成，以及沿着柱提供温度和/或流动相速度梯度柱。

24. 发明申请

WO2005007264A3 SEPARATION DEVICE WITH INTEGRAL GUARD COLUMN 审中-公开
标题翻译：具有整体保护柱的分离装置
公开(公告)号：WO2005007264A3
公开(公告)日：2005-05-19
申请号：PCT/US2004022374
申请日：2004-07-12
申请人： WATERS INVESTMENTS LTD , GRANGER JENNIFER HARNISCH , PLUMB ROBERT
发明人： GRANGER JENNIFER HARNISCH , PLUMB ROBERT
IPC分类号： B01D20060101 , B01D15/08 , G01N30/60
CPC分类号： B01D15/22 , G01N30/60 , G01N30/6039 , G01N30/6065 , G01N30/6069 , G01N2030/085
摘要： A separation device (2) is formed of a first tube (10) with a cylindrical wall (11) enclosing a chamber (16) having a first diameter, where the device has a first end (18) for discharging a fluid. At least two stationary phase medias are packed into the chamber (11) with separating frits (24) between the medias. At least one end frit element (22), secured to an inner surface of the first tube (10) contains the media in its section of the chamber (11) and allows the beds (30, 32) formed of the media to be formed and packed. When the separation device (2) so constructed forms a nanocolumn with a guard bed, the guard bed may be cleaved from the separation device (2) extending the useful life of the nanocolumn. When the separation device (2) so constructed comprises two analytical sections, and a plurality guard beds, complex analysis may be performed on a column having an extended useful life.
摘要翻译：分离装置（2）由具有包围具有第一直径的室（16）的圆柱形壁（11）的第一管（10）形成，其中该装置具有用于排出流体的第一端（18）。至少两个固定相介质被填充到腔室（11）中，分离介质之间的玻璃料（24）。固定到第一管（10）的内表面的至少一个端部玻璃料元件（22）在其腔室（11）的部分中包含介质，并允许形成由介质形成的床（30,32）并打包。当如此构造的分离装置（2）形成具有保护床的纳米柱时，保护床可以从延长纳米柱的使用寿命的分离装置（2）裂开。当如此构造的分离装置（2）包括两个分析部分和多个保护床时，可以对具有延长的使用寿命的柱进行复杂分析。

25. 发明申请

WO2003103835A1 MICRO FLUIDIC STRUCTURES 审中-公开
标题翻译：微流体结构
公开(公告)号：WO2003103835A1
公开(公告)日：2003-12-18
申请号：PCT/SE2003/000919
申请日：2003-06-04
申请人： ÅMIC AB , ÖHMAN, Per, Ove , MENDEL-HARTVIG, Ib
发明人： ÖHMAN, Per, Ove , MENDEL-HARTVIG, Ib
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L3/502746 , B01L3/502761 , B01L2200/0668 , B01L2300/18 , B01L2400/0406 , B01L2400/086 , G01N30/6065 , G01N30/6095 , G01N2030/525 , Y10T436/25
摘要： The invention relates to a micro fluidic system comprising a substrate, and, provided on said substrate, at least one flow path interconnecting with functional means in which liquid samples can be treated by desired procedures. The flow paths are laid out to form a pattern for the transport of liquid samples to and from said functional means. These flow paths comprise a plurality of micro posts protruding upwards from said substrate, the spacing between the micro posts being small enough to induce a capillary action in a liquid sample applied anywhere within any of said flow paths, so as to force said liquid to move from where said liquid sample was applied.
摘要翻译：本发明涉及一种微流体系统，其包括衬底，并且在所述衬底上提供与功能装置相互连接的至少一个流路，其中可以通过期望的程序处理液体样品。布置流动路径以形成用于将液体样品运送到所述功能装置和从所述功能装置输送液体样品的图案。这些流动路径包括从所述基底向上突出的多个微柱，微柱之间的间隔足够小，以在任何一个所述流动路径内的任何地方施加液体样品中的毛细管作用，以迫使所述液体移动从其中应用所述液体样品。

26. 发明申请

WO2003044519A1 分離装置、分離方法および分離装置の製造方法审中-公开
标题翻译：分离装置，分离方法和生产分离装置的方法
公开(公告)号：WO2003044519A1
公开(公告)日：2003-05-30
申请号：PCT/JP2002/012131
申请日：2002-11-20
申请人：日本電気株式会社 , 飯田一浩 , 馬場雅和 , 川浦久雄 , 佐野亨 , 阪本利司 , 井口憲幸 , 染谷浩子
发明人：飯田一浩 , 馬場雅和 , 川浦久雄 , 佐野亨 , 阪本利司 , 井口憲幸 , 染谷浩子
IPC分类号： G01N30/60
CPC分类号： B01J20/28 , B01J20/3285 , B01J2219/00837 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2200/0663 , B01L2300/0816 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , B01L2400/086 , B01L2400/088 , C03C17/30 , C03C27/10 , C03C2218/328 , G01N1/40 , G01N30/02 , G01N30/6065 , G01N30/6069 , G01N33/491 , G01N2013/003 , G01N2030/521 , B01D15/345 , B01D15/34
摘要： A technique for separation by which a sample can be separated in a short time with excellent resolution even when the sample amount is small and which is less apt to pose a problem such as clogging. Many hydrophobic regions 705 are disposed in a passageway for samples so that the regions 705 are apart from one another nearly evenly and that , in the areas other than the hydrophobic regions 705, the surface of a hydrophilic base 701 is exposed.
摘要翻译：即使在样品量小且不太容易引起堵塞等问题的情况下，也可以在短时间内以高分辨率分离样品的分离技术。许多疏水区域705设置在用于样品的通道中，使得区域705几乎均匀地彼此分开，并且在除了疏水区域705之外的区域中，亲水基底701的表面被暴露。

27. 发明申请

WO01007138A1 FILTRATION/SEPARATION CONTAINER WITHOUT AN IN-BUILT FILTER 审中-公开
标题翻译：无内置过滤器的过滤/分离容器
公开(公告)号：WO01007138A1
公开(公告)日：2001-02-01
申请号：PCT/US2000/020132
申请日：2000-07-25
IPC分类号： B01D15/08 , G01N30/60
CPC分类号： B01D15/22 , B01D15/362 , B01D15/363 , G01N30/6004 , G01N30/603 , G01N30/6065
摘要： This invention relates to a container, housing or column designed to perform filtration or sample separation without the use of a filter in said container. The present invention consists of a container that has one or more perforations, incisions or holes at its closed, bottom end. Such perforations, incisions or holes are large enough to permit the passage of fluids or smaller particles, but small enough to block the passage of solid materials or larger particles, such as chromatography support media. This device can thus be used for the filtration or separation of samples without the use of a filter in the container, where said filter would be used to hold the solid matrix or column material in the container. The container described herein can be used for sample separation or purification using a vacuum, pressure, centrifugation, gravitation or other separation methods.
摘要翻译：本发明涉及一种设计用于在所述容器中不使用过滤器的情况下进行过滤或样品分离的容器，外壳或柱。本发明包括在其封闭的底端具有一个或多个穿孔，切口或孔的容器。这种穿孔，切口或孔足够大以允许流体或较小颗粒通过，但足够小以阻止固体材料或较大颗粒（例如色谱支持介质）的通过。因此，该装置可以用于样品的过滤或分离，而不需要在容器中使用过滤器，其中所述过滤器将用于将固体基质或柱材料保持在容器中。本文所述的容器可用于使用真空，压力，离心，重力或其它分离方法的样品分离或纯化。

28. 发明申请

WO1985005285A1 HEAD FOR A PREPARATIVE COLUMN 审中-公开
标题翻译：制备柱头
公开(公告)号：WO1985005285A1
公开(公告)日：1985-12-05
申请号：PCT/EP1985000228
申请日：1985-05-13
申请人： WEAVER, Victor, Charles
IPC分类号： B01D15/08
CPC分类号： B01D15/08 , B01J8/0278 , G01N30/6004 , G01N30/6017 , G01N30/6065
摘要： A head for uniformly dispersing a liquid over the input surface of a chromatographic or reactive bed in a preparative column having a predetermined back pressure per unit flow rate, comprising an inlet tube through which the liquid is supplied. According to the invention the inside of the head (1) is profiled so that the vertical liquid flow through the bed is equated to the horizontal liquid flow in the head with due consideration to said back pressure of the column.
摘要翻译：用于在具有每单位流速的预定背压的制备柱中的色谱或反应床的输入表面上均匀分散液体的头部，包括供给液体的入口管。根据本发明，头部（1）的内部被成形，使得垂直的液体流过床层等于头部中的水平液体流动，同时考虑到柱的所述背压。

30. 发明专利

JP5741872B2 容器に収容された物質の分割方法有权
标题翻译：容纳在容器中除以物质的方法
公开(公告)号：JP5741872B2
公开(公告)日：2015-07-01
申请号：JP2013521513
申请日：2012-05-31
申请人：株式会社島津製作所
发明人：大橋鉄雄 , 老川幸夫 , 品田恵
IPC分类号： G01N30/60 , B65D79/00 , B01L3/14
CPC分类号： B01D15/22 , B01L3/5021 , B01L3/502784 , B65D81/32 , G01N30/6052 , G01N30/6065 , B01J19/00 , B01L2200/0673 , B01L2200/0689 , B01L2300/0858 , B01L2300/087 , B01L2300/123 , B01L2400/0409 , B01L2400/043

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