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21. 发明专利

JP2012245403A System and method for cardiac rhythm management 有权
标题翻译： CARDIAC RHYTHM管理系统与方法
公开(公告)号：JP2012245403A
公开(公告)日：2012-12-13
申请号：JP2012206330
申请日：2012-09-19
申请人： Cardiac Pacemakers Inc , カーディアックペースメイカーズ, インコーポレイテッド
发明人： ZHANG GENG , GARG ANKUR , DAUM DOUGLAS R
IPC分类号： A61N1/368
CPC分类号： A61N1/371 , A61B5/04525 , A61B5/7217 , A61B5/7264 , A61N1/368 , A61N1/3714
摘要： PROBLEM TO BE SOLVED: To provide a method and a system for classifying cardiac response to a pacing pulse and avoiding retrograde cardiac conduction.SOLUTION: A medical care system includes: a pacing circuit which is constituted to send out the pacing pulse to a patient; a detection circuit which is constituted to detect a cardiac signal associated with the pacing pulse; and a cardiac response processor which is connected to the detection circuit and which is constituted to set baseline amplitude of the cardiac signal by using data acquired in a certain period in advance of transmission of the pacing pulse and to determine the cardiac response to the pacing pulse by using the baseline amplitude.
摘要翻译：要解决的问题：提供一种用于将心脏反应分类到起搏脉冲并避免逆行心脏传导的方法和系统。解决方案：医疗保健系统包括：起搏电路，其被构造成将起搏脉冲发送给患者; 检测电路，其被构造成检测与所述起搏脉冲相关联的心脏信号; 以及心脏响应处理器，其连接到所述检测电路，并且被构造成通过使用在所述起搏脉冲的发送之前的特定时段中获取的数据来设置所述心脏信号的基线幅度，并且确定对所述起搏脉冲的心脏响应通过使用基线振幅。版权所有（C）2013，JPO＆INPIT

22. 发明专利

JP2012020185A Baroreflex modulation based on monitored cardiovascular parameter 审中-公开
标题翻译：基于监测心脏参数的BAROREFLEX调制
公开(公告)号：JP2012020185A
公开(公告)日：2012-02-02
申请号：JP2011237712
申请日：2011-10-28
申请人： Cardiac Pacemakers Inc , カーディアックペースメイカーズ, インコーポレイテッド
发明人： LIBBUS IMAD
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/36139 , A61N1/36053 , A61N1/36114 , A61N1/36117 , A61N1/3627 , A61N1/36514 , A61N1/37235
摘要： PROBLEM TO BE SOLVED: To provide implantable medical devices and, more particularly, modulating baroreflex stimulation to provide a desired heart rate.SOLUTION: An embodiment of a system comprises a heart rate monitor to sense a heart rate and provide a signal indicative of the heart rate, and a baroreflex stimulator. The stimulator includes a pulse generator to intermittently generate a stimulation signal to provide baroreflex stimulation for a baroreflex therapy, and further includes a modulator to adjust the stimulation signal based on the signal indicative of the heart rate such that the stimulation signal provides a desired baroreflex stimulation corresponding to the desired heart rate. Other aspects are provided herein.
摘要翻译：要解决的问题：提供可植入医疗装置，更具体地，调节压力反射刺激以提供期望的心率。解决方案：系统的实施例包括用于感测心率并提供指示心率的信号的心率监测器和压力反射刺激器。刺激器包括脉冲发生器，间歇地产生刺激信号以提供压力反射治疗的压力反射刺激，并且还包括调节器，用于基于指示心率的信号来调节刺激信号，使得刺激信号提供期望的压力反射刺激对应于期望的心率。本文提供了其他方面。版权所有（C）2012，JPO＆INPIT

23. 发明专利

JP2010264263A Pacing system for diastolic dysfunction 审中-公开
标题翻译：用于脱胶功能的PACING系统
公开(公告)号：JP2010264263A
公开(公告)日：2010-11-25
申请号：JP2010152520
申请日：2010-07-02
申请人： Cardiac Pacemakers Inc , カーディアックペースメイカーズ, インコーポレイテッド
发明人： SALO RODNEY W , SALO MATTHEW
IPC分类号： A61N1/368 , A61N1/362 , A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61N1/3627 , A61N1/36514
摘要： PROBLEM TO BE SOLVED: To provide a cardiac pacing system which has a novel constitution. SOLUTION: Pacing pulses are delivered to one or more cardiac regions to improve diastolic performance in patients having diastolic dysfunction and/or heart failure. A cardiac pacing system executes a pacing algorithm using a parameter indicative of the diastolic performance as an input. The pacing pulses excite the one or more cardiac regions to redistribute the loading on the ventricular wall during diastole, thereby improving the diastolic performance by lowering the degree of cardiac wall motion dyssynchrony associated with diastolic dysfunction. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供具有新颖构成的心脏起搏系统。解决方案：起搏脉冲被输送到一个或多个心脏区域以改善具有舒张功能障碍和/或心力衰竭的患者的舒张性能。心脏起搏系统使用表示舒张性能的参数作为输入来执行起搏算法。起搏脉冲激发一个或多个心脏区域以在舒张期期间重新分布心室壁上的负荷，从而通过降低与心脏舒张功能障碍相关的心脏壁运动不同步的程度来改善舒张性能。版权所有（C）2011，JPO＆INPIT

24. 发明专利

JP2008173513A Atp pacing with entrainment monitoring 审中-公开
标题翻译： ATP PACING WITH INTRAINMENT MONITORING
公开(公告)号：JP2008173513A
公开(公告)日：2008-07-31
申请号：JP2008100821
申请日：2008-04-08
申请人： Cardiac Pacemakers Inc , カーディアック・ペースメーカーズ・インコーポレーテッド
发明人： ZHANG YUNLONG
IPC分类号： A61N1/365 , A61N1/362 , A61N1/37
CPC分类号： A61N1/371 , A61N1/3622
摘要： PROBLEM TO BE SOLVED: To provide an applying method for delivering ATP therapy in a manner that increases the likelihood that ATP therapy will terminate a tachyarrhythmia without resorting to defibrillation shock. SOLUTION: Sense signals representing electrical activity in a heart chamber is generated and a chamber sense is detected when a sense signal exceeds a specified intrinsic detection threshold. A tachycardia is detected in the heart chamber when a rate at which chamber senses are detected exceeds a specified tachycardia threshold value. Upon detection of a tachycardia, a burst of one or more pacing pulses is delivered in accordance with an anti-tachycardia pacing protocol and the burst is outputted after a specified coupling interval with respect to a chamber sense. If a pacing pulse has captured the heart chamber by detecting whether an evoked response occurs during a capture detection window following the output of a pacing pulse is determined. The extent to which the heart chamber has been entrained by counting the number of successive pacing pulses achieving capture during the burst is determined. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种以增加ATP治疗在不诉诸除颤休克的情况下终止快速性心律失常的可能性来递送ATP治疗的施用方法。解决方案：当感测信号超过指定的内在检测阈值时，产生表示心脏室中电活动的感测信号，并检测腔室感测。当检测到室感觉的速率超过规定的心动过速阈值时，在心室中检测到心动过速。在检测到心动过速时，根据抗心动过速起搏协议递送一个或多个起搏脉冲的脉冲串，并且在相对于腔室感应指定的耦合间隔之后输出突发。如果起搏脉冲通过检测在确定起搏脉冲的输出之后的捕获检测窗口期间是否发生诱发的响应来捕获心室。确定通过计数在突发期间实现捕获的连续起搏脉冲的数目来夹带心室的程度。版权所有（C）2008，JPO＆INPIT

25. 发明专利

JPH06304257A METHOD AND DEVICE FOR MANAGING AND MONITORING CADIAC RHYTHM USING ACTION TIME OF HEART AS CONTROL PARAMETER 失效
公开(公告)号：JPH06304257A
公开(公告)日：1994-11-01
申请号：JP8088093
申请日：1993-04-07
申请人： CARDIAC PACEMAKERS INC
发明人： JIYURIO SHII SUPINERI
IPC分类号： A61N1/365
摘要： PURPOSE: To provide a managing apparatus for cardiac rhythm using cardiac active time as control parameter by generating control signals relative to the total active time of cardiac cycle defined by the interval between the ends of congestive stages and transmitting them to a variable-speed pulse generating device. CONSTITUTION: In a managing apparatus for cardiac rhythm having a variable- speed pulse generating device 42, a microprocessor 32 measures the impedance change of the heart due to change of blood volume in the heart and detects the generation of depolarization signal of natural or stimulated cardiac motion. The total active time of cardiac cycle obtained from the impedance change is begun by the generation of depolarization signal, and it is assumed that the heart is filled up again in a fast congestive speed. The total active time of cardiac cycle defined by the interval between the ends of congestive stages are calculated, control signals relative to the total cardiac active time are generated and transmitted to a pulse generating device 42.

26. 发明专利

JPH06277299A FIBRILLATION-ELIMINATING PATCH ELECTRODE WITH NON-CONDUCTIVE ELASTIC AREA 失效
公开(公告)号：JPH06277299A
公开(公告)日：1994-10-04
申请号：JP24508593
申请日：1993-09-30
申请人： CARDIAC PACEMAKERS INC
发明人： BURUUSU EICHI KENNAITO , JIEFURII EI HOORU
IPC分类号： A61N1/05 , A61N1/39
摘要： PURPOSE: To prevent a permanent deformation of electrode-conduction surface after being introduced into pectus by installing two conductive elements which are separated from each other by non-conductive regions of insulating element, and placing a hinge surrounding an electrode which deflects on a priority basis from an orientation of a flat plane in a state where the non-conductive region is substantially relaxed to the orientation of being folded. CONSTITUTION: Defibrillation/fibrillation removal electrode assembly body 10 is composed of a plane conductive-electrode part 12 and a lead wire member 14. In this case an electrode part 12 is formed by conductive elements 16 and 18 installed to repoussage-element 20 which is an electrical insulant and which is mechanically elastic as an entirety. Further, the conductive elements 16 and 18 as network structure of wires are separated from each other on the repoussage-element 20 by a non-network region 30. The electrode part 12 is deflected along a broken line 32 by the non-network region 30. In this case, the non-network region 30 acts as a spring-loaded hinge. Thus, a permanent deformation of the electrode-conductive surface after treatment of introduction into the pectus is eliminated.

27. 发明专利

JPH06169997A FIBRILLATION REMOVING ELECTRODE 失效
公开(公告)号：JPH06169997A
公开(公告)日：1994-06-21
申请号：JP12632193
申请日：1993-05-27
申请人： CARDIAC PACEMAKERS INC
发明人： RONARUDO DABURIYUU HAIRU JIYUN , ROBAATO DABURIYUU UITSUKAMU JI , BURUUSU EICHI KENKUNAITO
IPC分类号： A61N1/05 , A61N1/39
摘要： PURPOSE: To facilitate a detachable insertion of electrode into a tissue by providing a movable hook between a position of a hook housing within a hollowed part made at the end of catheter and the other position of a hook projecting from the hollowed part, and composing of connecting the hook to the tissue by being laterally displaced when the hook is projected. CONSTITUTION: This fibrillation eliminative electrode, namely electro-catheter 10 has a straightly unfoldable end 12 by inserting an internal probe into the tissue from a basic end 14 and a helical spring 22 is housed into a dielectric tubular housing 19 in the end 12. The end 20 of the helical spring 22 has an enlarged part 24 of an enlarged diameter, the enlarged part 24 is moved to the axial direction by an axially directed thrust-increasing means. A basic end 28 of the hook of a spring hook 30 being opposite in direction is connected to a top-tip 26 of the helical spring 22, and the hook 30 is moved in the lateral direction by projecting a curved part 23 of the hook 30 from the opening part 18 when the spring 22 is advanced, and while being in this state, removing a fixing type probe to return the hook 30, the hook 30 penetrates into an organic tissue.

28. 发明专利

JPH0698940A DEFIBRILLATION AND ELECTRIC DEFIBRILLA- TION SYSTEM AND METHOD 失效
公开(公告)号：JPH0698940A
公开(公告)日：1994-04-12
申请号：JP18792792
申请日：1992-07-15
申请人： CARDIAC PACEMAKERS INC
发明人： ROIDO BUAN HOUEEGEN , JINCHIYUI FUSAN , DANIERU HANTOWAAFU
IPC分类号： A61N1/39
摘要： PURPOSE: To avoid an unnecessary shock to a heart, by monitoring the activity of the heart during and after charging to a defibrillation capacitor, making the capacitor discharge after evaluating the condition of the heart, and applying the charge onto the heart. CONSTITUTION: Detecting and discharging electrodes 12, 14 mounted on or in the vicinity of a heart are connected to an ECG(electrocardiogram) sensitivity amplifier 16 comprising an AGC(automatic gain controller), and signals outputted by the amplifier 16 are inputted into a heart condition detector 18 and a logical part 20 to analyze the activity of the heart. When irregular pulse is detected, a shock avoidable algorithm is started to charge a discharge capacitor 24 with monitoring a heart, and, after charging for 2 seconds, the interval of the R wave is checked and compared with a preset value. When the interval of the P wave exceeded the preset value, the system goes into a delay process for 2 seconds and the capacitor 24 is discharged to apply the charge to the heart when the irregular pulse is not eliminated.

29. 发明专利

JPH0698864A SCREENING METHOD FOR MYOCARDINAL ISCHEMIA PATIENT 失效
公开(公告)号：JPH0698864A
公开(公告)日：1994-04-12
申请号：JP31860592
申请日：1992-11-27
申请人： CARDIAC PACEMAKERS INC
发明人： JIYON SHII POTOTSUKI
IPC分类号： A61B5/0452 , A61N1/365 , A61N1/37
摘要： PURPOSE: To screen a patient by obtaining a reference wave form from an electrocardiograph obtained by connecting a pacing lead with detecting and pacing electrodes in a pace maker embedded into a body, storing the reference wave form in an external programmer to compare new one with the reference wave form. CONSTITUTION: A lead 14 a pacing electrode 16 and a detecting electrode 18 at the tip end is inserted from the large vein 20 to the right ventricle 24 via the right atrium 22 of a heart, and a pace maker 12 embedded in a body is connected to the other end of the lead 14. After the pacing electrode 16 and the lead 16 come into a stable condition, data interpreting a cardiograph is detected and stored in the pace maker 12 as the reference value and also transmitted to and stored in a programmer unit 10 as the reference value. Every time a new cardiograph is obtained, whether myocardial ischemia exists or not and the transition are judged noticing on changes of the cardiograph, especially on changes of the ST part. Thereby screening suitable for a patient is carried out.

30. 发明专利

JPH0564666A EMBEDDED INTRAVENOUS HEART STIMULATOR 失效
公开(公告)号：JPH0564666A
公开(公告)日：1993-03-19
申请号：JP18841991
申请日：1991-04-25
申请人： CARDIAC PACEMAKERS INC
发明人： ROBAATO JII HOOSAA
IPC分类号： A61N1/362 , A61N1/05 , A61N1/368 , A61N1/372 , A61N1/375 , A61N1/39
摘要： PURPOSE: To maintain the function of a heat in a normal condition by implanting a housing accommodating therein a pulse generator having an antiarrhythmic in the pacemaking function, an electric defibrillating function and a defibrillating function, in the vicinity of the heart so that a conductive surface of the housing faces the heat. CONSTITUTION: A conductive surface 14 of a housing 10 is connected to a pulse generator 18 through the intermediary of a program switch 16. The housing 10 is implanted in the vicinity of the heart, with the conductive surface 14 facing the heart. The housing 10 has a socket assembly 20 which is connected with a lead wire from a catheter whose leading end intravenously implanted in the vicinity of the heart. An input from the catheter is checked so that the program switch 16 selects an output of the pulse generator 18 so as to apply an electric shock upon the heat from the conductive surface 14, and accordingly, an electric shock depending upon a condition of arrhythmia or pulsus frequens, thereby it is possible to normally hold the function of the heart.

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