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21. 发明授权

US5304251A Crystalline lactulose trihydrate and a method for its manufacture 失效
标题翻译：结晶乳果糖三水合物及其制造方法
公开(公告)号：US5304251A
公开(公告)日：1994-04-19
申请号：US926308
申请日：1992-08-10
申请人： Mamoru Tomita , Seiichi Shimamura , Yoshitaka Tamura , Teruhiko Mizota , Satoshi Nakano , Itsuko Suzawa
发明人： Mamoru Tomita , Seiichi Shimamura , Yoshitaka Tamura , Teruhiko Mizota , Satoshi Nakano , Itsuko Suzawa
IPC分类号： A23L27/30 , C07H1/00 , C07H3/04 , C13B30/02 , C13K13/00 , C13F3/00 , C07H3/00 , C08B37/00
CPC分类号： C07H3/04 , A23L27/33 , C07H1/00 , C13K13/002
摘要： A crystalline lactulose trihydrate having molecular formula of C.sub.12 H.sub.22 O.sub.11.3H.sub.2 O and a method for its manufacture, which comprises crystallization from a lactulose syrup at a temperature of 2.degree.-20.degree. C., the starting lactulose syrup having a lactulose content of 70-90% of a total solid matters by weight, and having been concentrated to the total solid matters of 65-75% by weight and a ratio of lactose to water of less than 10% by weight.
摘要翻译：分子式为C12H22O11.3H2O的结晶乳果糖三水合物及其制造方法，其包括在2℃-20℃的温度下从乳果糖糖浆中结晶，所述起始乳果糖糖浆的乳果糖含量为70-90％的总固体重量，并且已经浓缩至总固体物质的65-75重量％，乳糖与水的比例小于10重量％。

22. 发明申请

US20130245305A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND 有权
标题翻译：生产异硫氰酸酯化合物的方法
公开(公告)号：US20130245305A1
公开(公告)日：2013-09-19
申请号：US13990312
申请日：2010-11-29
申请人： Junko Takada , Shunsuke Iwamoto , Satoshi Nakano
发明人： Junko Takada , Shunsuke Iwamoto , Satoshi Nakano
IPC分类号： C07C331/28
CPC分类号： C07C331/28
摘要： The object of the present invention is to provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) by a reaction of the corresponding amino compound having a carboxyl group(s), thiocarbonyldiimidazole and a base, in one step with high purity.An amino compound having a carboxyl group(s) is reacted with thiocarbonyldiimidazole in a solvent in the presence of a base to obtain an isothiocyanate compound having a carboxyl group(s).
摘要翻译：本发明的目的是提供一种具有羧基的具有羧基的相应氨基化合物，硫代羰基二咪唑和碱的具有羧基的异硫氰酸酯化合物的新方法，其中一步具有高的纯度。具有羧基的氨基化合物与硫代羰基二咪唑在溶剂中在碱存在下反应，得到具有羧基的异硫氰酸酯化合物。

23. 发明申请

US20130217894A1 ORGANIC AMINE SALTS OF AMINOBENZOIC ACID DERIVATIVES AND METHOD FOR PRODUCING SAME 有权
标题翻译：氨基苯甲酸衍生物的有机胺盐及其生产方法
公开(公告)号：US20130217894A1
公开(公告)日：2013-08-22
申请号：US13883171
申请日：2011-11-01
申请人： Shunsuke Iwamoto , Satoshi Nakano , Mariko Ishida , Masao Yamamoto , Kazuya Takeuchi
发明人： Shunsuke Iwamoto , Satoshi Nakano , Mariko Ishida , Masao Yamamoto , Kazuya Takeuchi
IPC分类号： C07D333/32
CPC分类号： C07D333/32 , A61K9/0019 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2059 , A61K9/4866 , A61K47/14
摘要： A novel organic amine salt or salt with quaternary ammonium ion of 3-{[((2E)-2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonothioyl]amino}benzoic acid having useful properties as a drug is provided.A novel organic amine or salt with quaternary ammonium ion of 3-{[((2E)-2-{1-[5-(4-t-butylphenyl)-4-hydroxy-3-thienyl]ethylidene}hydrazino)carbonothioyl]amino}benzoic acid, a method for producing the organic amine salt or the salt with quaternary ammonium ion and a platelet increasing agent.
摘要翻译：具有3 - {[（（2E）-2- {1- [5-（4-叔丁基苯基）-4-羟基-3-噻吩基]亚乙基}肼基）碳硫基的季铵离子的新型有机胺盐或盐 ]氨基}苯甲酸作为药物具有有用的性质。具有季铵离子的3 - {[（（2E）-2- {1- [5-（4-叔丁基苯基）-4-羟基-3-噻吩基]亚乙基}肼基）碳硫基] 氨基}苯甲酸，有机胺盐或其盐与季铵离子的制备方法和增白剂。

24. 发明授权

US08367857B2 Method for producing isothiocyanate compound having carboxyl group 有权
标题翻译：具有羧基的异硫氰酸酯化合物的制造方法
公开(公告)号：US08367857B2
公开(公告)日：2013-02-05
申请号：US12867339
申请日：2009-02-27
申请人： Satoshi Nakano , Daisuke Saito
发明人： Satoshi Nakano , Daisuke Saito
IPC分类号： C07C331/28 , C07C331/30 , C07C331/20
CPC分类号： C07C331/20 , C07C331/24 , C07C331/28 , C07C331/30 , C07C2601/14
摘要： To provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) from the corresponding amino compound having a carboxyl group(s).A method for producing an isothiocyanate compound which has a carboxyl group(s) and is represented by the formula (2). And the method comprises reacting an amino compound which has a carboxyl group(s) and is represented by the formula (1) (wherein A is e.g. a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group, and B is e.g. a single bond, a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group), in a solvent, with carbon disulfide (CS2) and then with a halogen as a simple substance.
摘要翻译：提供从具有羧基的相应氨基化合物制备具有羧基的异硫氰酸酯化合物的新方法。一种具有羧基并由式（2）表示的异硫氰酸酯化合物的制备方法。该方法包括使具有羧基的氨基化合物与由式（1）表示的氨基化合物反应（其中A为例如C 6-14芳族烃基或C 1-12饱和烃基，B为例如单键，C6-14芳族烃基或C1-12饱和烃基）在溶剂中与二硫化碳（CS2）反应，然后以卤素作为单一物质。

25. 发明授权

US08134013B2 Amide compound and thrombopoietin receptor activator 有权
标题翻译：酰胺化合物和血小板生成素受体激活剂
公开(公告)号：US08134013B2
公开(公告)日：2012-03-13
申请号：US11721786
申请日：2005-12-14
申请人： Katsuaki Myaji , Shunsuke Iwamoto , Satoshi Nakano , Hirofumi Ota , Yukihiro Shigeta , Yutaka Hirokawa , Kazufumi Yanagihara , Koji Toyama , Shingo Owada , Masato Horikawa , Norihisa Ishiwata
发明人： Katsuaki Myaji , Shunsuke Iwamoto , Satoshi Nakano , Hirofumi Ota , Yukihiro Shigeta , Yutaka Hirokawa , Kazufumi Yanagihara , Koji Toyama , Shingo Owada , Masato Horikawa , Norihisa Ishiwata
IPC分类号： C07D409/02 , A61K31/40
CPC分类号： C07D231/18
摘要： The present invention provides compounds useful for prevention, treatment or alleviation of diseases against which activation of the thrombopoietin receptor is effective.A compound represented by the formula (1): wherein A, B, R1, L1, R2, L2, L3, Y, L4, R3 and X are the same as defined in the description, a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.
摘要翻译：本发明提供了可用于预防，治疗或缓解血小板生成素受体活化有效的疾病的化合物。由式（1）表示的化合物：其中A，B，R1，L1，R2，L2，L3，Y，L4，R3和X与说明书中定义的相同，互变异构体，前药或药学上可接受的盐化合物或其溶剂合物。

26. 发明授权

US07079323B2 Surface treatment method and optical part 失效
公开(公告)号：US07079323B2
公开(公告)日：2006-07-18
申请号：US10456836
申请日：2003-06-09
申请人： Tatsuo Ohta , Satoshi Nakano , Hiroshi Hirayama
发明人： Tatsuo Ohta , Satoshi Nakano , Hiroshi Hirayama
IPC分类号： G02B25/00 , H05H1/24
CPC分类号： G02B1/10 , C23C16/452 , C23C16/45576 , C23C16/45595 , G02B1/11 , G21K2201/067 , H01J37/32082 , H05H1/24 , H05H1/2406 , H05H2001/2412 , H05H2001/2431 , H05H2001/2443
摘要： A surface treating method of forming a coating layer on a base material, comprising conducting a plasma processing under an atmospheric pressure for the base material so as to form a coating layer on the base material having at least one of a curved surface and an uneven surface.

27. 发明授权

US06863397B2 Optical element and eyeglass lens 有权
标题翻译：光学元件和眼镜镜片
公开(公告)号：US06863397B2
公开(公告)日：2005-03-08
申请号：US09905519
申请日：2001-07-13
申请人： Satoshi Nakano
发明人： Satoshi Nakano
IPC分类号： G02C7/02 , B32B7/02 , B32B9/00 , C03C17/34 , C23C14/06 , G02B1/11 , G02B1/116 , G02B1/16 , G02B5/20 , G02B5/28 , G02C7/10
CPC分类号： G02B1/116 , G02B1/16 , G02B5/208 , G02B5/283 , G02C7/02 , G02C7/10 , G02C2202/16
摘要： An optical element, comprises a base material; and a layer formed on at least one of surfaces of the base material. A reflectance of a surface of the formed layer for all light rays in a wavelength region of 280 nm to 315 nm and in a wavelength region of 420 nm to 680 nm is smaller than a reflectance of a surface of the base material.
摘要翻译：光学元件，包括基材; 以及形成在所述基材的至少一个表面上的层。在280nm至315nm的波长区域和420nm至680nm的波长区域中的所有光线的所形成的层的表面的反射率小于基底材料的表面的反射率。

28. 发明授权

US06852569B2 Method of fabricating multilayer ceramic substrate 有权
标题翻译：制造多层陶瓷基板的方法
公开(公告)号：US06852569B2
公开(公告)日：2005-02-08
申请号：US10281270
申请日：2002-10-28
申请人： Satoshi Nakano , Yoshio Mizuno , Junzo Fukuta , Katsuhiko Naka
发明人： Satoshi Nakano , Yoshio Mizuno , Junzo Fukuta , Katsuhiko Naka
IPC分类号： H05K1/16 , H01L21/48 , H01L23/12 , H05K1/03 , H05K3/46 , H01L21/44 , C03B29/00
CPC分类号： H05K3/4629 , H01L21/4857 , H01L21/4867 , H05K1/0306 , H05K3/4611 , H05K3/4697 , H05K2203/063 , H05K2203/308 , Y10T29/49124 , Y10T29/49126
摘要： A method of fabricating a multilayer ceramic substrate includes stacking one or a plurality of unfired ceramic greensheets on one or both sides of a previously fired ceramic substrate, thereby forming a stack, each unfired ceramic greensheet having a firing temperature substantially equal to or lower than a firing temperature of the previously fired ceramic substrate, stacking a restricting greensheet on the unfired ceramic greensheet composing an outermost layer of the stack, the restricting greensheet having a higher firing temperature than each unfired ceramic greensheet, firing the stack at the firing temperature of the unfired ceramic green sheets with or without pressure applied via the restricting greensheet while the stack is under restriction by the restricting greensheet, thereby integrating the stack, and eliminating remainders of the restricting greensheet after the firing step.
摘要翻译：制造多层陶瓷基板的方法包括在先前烧制的陶瓷基板的一侧或两侧堆叠一个或多个未烧制的陶瓷片，从而形成堆叠，每个未焙烧的陶瓷毛坯的烧制温度基本上等于或低于烧结的陶瓷基板的烧成温度，在构成叠层的最外层的未烧成的陶瓷毛坯上堆叠限制毛坯，限制毛坯的焙烧温度高于每个未烧成的陶瓷毛坯，在未烧制的烧成温度下烧成叠层陶瓷生片通过限制毛坯施加或不施加压力，同时堆叠受到限制毛坯的限制，从而整合堆叠，并且在烧制步骤之后消除限制毛坯的剩余部分。

29. 发明授权

US5920431A Optical member having antireflection film thereon 失效
标题翻译：具有防反射膜的光学部件
公开(公告)号：US5920431A
公开(公告)日：1999-07-06
申请号：US879984
申请日：1997-06-20
申请人： Setsuo Tokuhiro , Satoshi Nakano , Tatsuo Ohta
发明人： Setsuo Tokuhiro , Satoshi Nakano , Tatsuo Ohta
IPC分类号： G02B1/11 , G02B1/10
CPC分类号： G02B1/115
摘要： An optical member includes a synthetic resin substrate: and an antireflection film including at least a mixture film composed of tantalum oxide (Ta.sub.2 O.sub.5) and titanium oxide (TiO.sub.2), and a film having a refractive index lower than that of the mixture film. The antireflection film is coated on the synthetic resin substrate.
摘要翻译：光学构件包括合成树脂基板和至少包括由氧化钽（Ta 2 O 5）和氧化钛（TiO 2）组成的混合膜的抗反射膜和折射率低于混合膜的折射率的膜。防反射膜涂覆在合成树脂基板上。

30. 发明授权

US5602616A Exposure control apparatus of camera 失效
标题翻译：照相机曝光控制装置
公开(公告)号：US5602616A
公开(公告)日：1997-02-11
申请号：US380314
申请日：1995-01-30
申请人： Osamu Sato , Satoshi Nakano , Isamu Hirai , Toshiyuki Kitazawa , Takayuki Sensui , Masato Yamamoto , Toshimasa Yamanaka , Takenao Shishikura , Akio Takahashi , Nobuhiko Matsudo
发明人： Osamu Sato , Satoshi Nakano , Isamu Hirai , Toshiyuki Kitazawa , Takayuki Sensui , Masato Yamamoto , Toshimasa Yamanaka , Takenao Shishikura , Akio Takahashi , Nobuhiko Matsudo
IPC分类号： G03B7/08 , G03B7/097
CPC分类号： G03B7/097 , G03B7/0807
摘要： A camera having a manually actuable switch for temporarily shifting the camera to an optimum exposure value so that exposure factors, based upon a manually set shutter speed and a manually set aperture value, are replaced by optimum exposure factors based upon a metered brightness of the object to be photographed when the camera is set to a non-program exposure mode. A clear button associated with the camera functions as a manually actuable switch for temporarily shifting an exposure mode of the camera to another exposure mode when the camera is set to a hyper-manual exposure mode. In the hyper-manual exposure mode, a photographer sets exposure factors by actuating a Tv electronic dial and an Av electronic dial. Actuation of the clear button when the camera is set to the hyper-manual exposure mode causes the set exposure factors to be replaced with optimum exposure factors that are automatically calculated in accordance with an object brightness Bv. Thus, operating the clear button (manually actuable switch for temporarily shifting to another exposure mode) results in the mode of the camera being changed from a mode in which exposure factors are manually set by a photographer (via the setting of a shutter speed and an aperture value) to a mode in which optimum exposure factors are set based upon a calculation performed by a processor of the camera.
摘要翻译：一种具有手动开关的照相机，用于临时将相机移动到最佳曝光值，使得基于手动设定的快门速度和手动设定的光圈值的曝光因子被基于对象的计量亮度的最佳曝光因子所替代当相机设置为非程序曝光模式时要拍摄。与相机相关联的清除按钮用作手动开关，用于当相机设置为超手动曝光模式时将相机的曝光模式临时移动到另一曝光模式。在超手动曝光模式中，摄影师通过启动电视电子拨号盘和Av电子拨盘来设置曝光因素。当相机设置为超手动曝光模式时，清除按钮的启动使得设置的曝光因子被替换为根据对象亮度Bv自动计算的最佳曝光因子。因此，操作清除按钮（用于临时移动到另一曝光模式的手动开关）导致相机的模式从摄影者手动设置曝光因子的模式（通过快门速度和光圈值）到基于由照相机的处理器进行的计算而设定最佳曝光因子的模式。

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