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21. 发明授权

US07062941B2 Manufacturing method of optical fiber preform 有权
标题翻译：光纤预制棒的制造方法
公开(公告)号：US07062941B2
公开(公告)日：2006-06-20
申请号：US10103786
申请日：2002-03-25
申请人： Masashi Onishi , Eiji Yanada , Masaaki Hirano , Hideyuki Ijiri
发明人： Masashi Onishi , Eiji Yanada , Masaaki Hirano , Hideyuki Ijiri
IPC分类号： C03B37/07
CPC分类号： C03B37/01228
摘要： A method for manufacturing an optical fiber preform that can produce an optical fiber having desired characteristics over the longer length thereof. A crude preform provided with a core region and a cladding region is prepared (Step S1), and at a plurality of positions in the longitudinal direction of the crude preform, a refractive index profile in the cross-section of the crude preform is measured (Step S2). Then, the shape of the cladding region is demarcated based on the shape of the profile (Step S3). Subsequently, the crude preform is ground based on the results of the demarcation (Step S4). Thus, an optical fiber preform that enables the manufacture of an optical fiber having target characteristics is manufactured.
摘要翻译：一种光纤预制棒的制造方法，该光纤预制棒可以在其较长的长度上产生具有所需特性的光纤。制备具有芯区域和包层区域的粗制预制件（步骤S1），并且在粗制预型件的纵向方向上的多个位置处，测量粗制预成型体的横截面中的折射率分布（步骤S2）。然后，基于轮廓的形状划定包层区域的形状（步骤S 3）。随后，基于划分的结果研磨粗制预成型件（步骤S4）。因此，制造能够制造具有目标特性的光纤的光纤预制棒。

22. 发明授权

US07045737B2 Glass-processing method and glass-processing apparatus for the method 有权
标题翻译：玻璃加工方法和玻璃加工装置的方法
公开(公告)号：US07045737B2
公开(公告)日：2006-05-16
申请号：US10780716
申请日：2004-02-19
申请人： Masashi Onishi , Masaaki Hirano , Tetsuya Nakanishi
发明人： Masashi Onishi , Masaaki Hirano , Tetsuya Nakanishi
IPC分类号： B23K9/00
CPC分类号： H05H1/30 , C03B23/043 , C03B23/207 , C03B29/02 , C03B37/0124 , C03B37/01815 , C03B37/01823 , Y02P40/57
摘要： A glass-processing method adjusts the range of the heating region according to the work piece and processing condition, and a glass-processing apparatus implements the method. The method incorporates the heating of a glass body with a thermal plasma torch comprising (a) a main body provided with a plurality of ports from which a gas issues and (b) a device for applying a high-frequency electric field to the gas fed into the main body. The method comprises the steps of (1) adjusting the plasma flame's size perpendicular to the center axis of the main body by controlling the flow rate of the gas fed into each port according to the size of the glass body, the processing condition, or both and (2) heating the glass body. The apparatus comprises (a) a thermal plasma torch for heating a glass body, comprising (a1) a main body provided with a plurality of ports from which a gas issues and (a2) a device for applying a high-frequency electric field to the gas fed into the main body and (b) a device for adjusting the flow rate of the gas fed into each port.
摘要翻译：玻璃加工方法根据工件和加工条件调节加热区域的范围，玻璃加工装置实施该方法。该方法包括用热等离子体焰炬加热玻璃体，其包括（a）主体，其设置有多个端口，气体从该端口发出，以及（b）用于将高频电场施加到气体馈送的装置进入主体。该方法包括以下步骤：（1）通过根据玻璃体的尺寸，加工条件或两者来控制进入每个端口的气体的流量来调节垂直于主体的中心轴的等离子体火焰的尺寸和（2）加热玻璃体。该装置包括：（a）用于加热玻璃体的热等离子体焰炬，包括（a1）设置有气体发生的多个端口的主体，以及（a2）用于将高频电场施加到送入主体的气体和（b）用于调节供给到每个端口的气体的流量的装置。

23. 发明申请

US20050267110A1 Propane-1, 3-dione derivative 有权
标题翻译：丙烷-1,3-二酮衍生物
公开(公告)号：US20050267110A1
公开(公告)日：2005-12-01
申请号：US11155595
申请日：2005-06-20
申请人： Masaaki Hirano , Eiji Kawaminami , Akira Toyoshima , Hiroyuki Moritomo , Norio Seki , Ryutaro Wakayama , Minoru Okada , Toshiyuki Kusayama
发明人： Masaaki Hirano , Eiji Kawaminami , Akira Toyoshima , Hiroyuki Moritomo , Norio Seki , Ryutaro Wakayama , Minoru Okada , Toshiyuki Kusayama
IPC分类号： A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4439 , A61K31/454 , A61K31/4725 , A61K31/506 , A61K31/5377 , A61P5/24 , A61P35/00 , C07D235/06 , C07D235/12 , C07D277/64 , C07D277/84 , C07D339/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , A61K31/53 , A61K31/385 , A61K31/423
CPC分类号： C07D401/06 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4439 , A61K31/454 , A61K31/4725 , A61K31/506 , A61K31/5377 , C07D235/06 , C07D235/12 , C07D277/64 , C07D277/84 , C07D339/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
摘要： Provided is a pharmaceutical composition containing a propane-1,3-dione derivative as the active ingredient, particularly a GnRH receptor antagonist. Also, provided is a propane-1,3-dione derivative having a GnRH antagonistic effect.
摘要翻译：本发明提供含有丙-1,3-二酮衍生物作为活性成分，特别是GnRH受体拮抗剂的药物组合物。此外，提供具有GnRH拮抗作用的丙烷-1,3-二酮衍生物。

24. 发明授权

US06960591B2 Propane-1,3-dione derivative 有权
标题翻译：丙烷-1,3-二酮衍生物
公开(公告)号：US06960591B2
公开(公告)日：2005-11-01
申请号：US10311688
申请日：2001-07-04
申请人： Masaaki Hirano , Eiji Kawaminami , Akira Toyoshima , Hiroyuki Moritomo , Norio Seki , Ryutaro Wakayama , Minoru Okada , Toshiyuki Kusayama
发明人： Masaaki Hirano , Eiji Kawaminami , Akira Toyoshima , Hiroyuki Moritomo , Norio Seki , Ryutaro Wakayama , Minoru Okada , Toshiyuki Kusayama
IPC分类号： A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4439 , A61K31/454 , A61K31/4725 , A61K31/506 , A61K31/5377 , A61P5/24 , A61P35/00 , C07D235/06 , C07D235/12 , C07D277/64 , C07D277/84 , C07D339/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
CPC分类号： C07D401/06 , A61K31/4184 , A61K31/422 , A61K31/427 , A61K31/428 , A61K31/4439 , A61K31/454 , A61K31/4725 , A61K31/506 , A61K31/5377 , C07D235/06 , C07D235/12 , C07D277/64 , C07D277/84 , C07D339/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04
摘要： Provided is a pharmaceutical composition containing a propane-1,3-dione derivative as the active ingredient, particularly a GnRH receptor antagonist. Also, provided is a propane-1,3-dione derivative having a GnRH antagonistic effect.
摘要翻译：本发明提供含有丙-1,3-二酮衍生物作为活性成分，特别是GnRH受体拮抗剂的药物组合物。此外，提供具有GnRH拮抗作用的丙烷-1,3-二酮衍生物。

25. 发明授权

US06400877B1 Negative-dispersion optical fiber and optical transmission line incorporating the same 有权
标题翻译：负分散光纤和包含其的光传输线
公开(公告)号：US06400877B1
公开(公告)日：2002-06-04
申请号：US09879103
申请日：2001-06-13
申请人： Takatoshi Kato , Masaaki Hirano
发明人： Takatoshi Kato , Masaaki Hirano
IPC分类号： G02B602
CPC分类号： G02B6/02261 , G02B6/02004 , G02B6/0228 , G02B6/03627 , G02B6/03644 , G02B6/29377
摘要： The present invention concerns a negative-dispersion optical fiber for compensating in a shorter length for chromatic dispersion of a positive-dispersion optical fiber in a signal wavelength band, and an optical transmission line incorporating it. The negative-dispersion optical fiber has the following properties at the wavelength of 1550 nm; chromatic dispersion D of not more than −150 ps/nm/km; a dispersion slope satisfying such a condition that a ratio thereof (S/D) to the chromatic dispersion D is not less than 2.0×10−3/nm nor more than 4.7×1031 3/nm; and an effective area of not less than 12 &mgr;m2 but less than 25 &mgr;m2. For satisfying these properties, the negative-dispersion optical fiber has, in the order stated from the center toward the outer periphery, a core region of a maximum refractive index n1, a first cladding of a refractive index n2 ( n2), and a third cladding of a refractive index n4 (
摘要翻译：本发明涉及用于在信号波长带中的正色散光纤的色散在较短长度上进行补偿的负色散光纤以及包括其的光传输线。负色散光纤在1550nm的波长下具有以下性质：色散D不大于-150ps / nm / km; 满足（S / D）与色散D的比例为2.0×10 -3 / nm以上4.7×10 31 3 / nm以下的条件的色散斜率; 有效面积不低于12mum2但小于25mum2。为了满足这些特性，负色散光纤以从中心向外周的顺序具有最大折射率n1的芯区域，折射率n2（ n2）的包层和折射率n4（

26. 发明申请

US20120321261A1 METHOD FOR PRODUCING OPTICAL FIBER 审中-公开
标题翻译：生产光纤的方法
公开(公告)号：US20120321261A1
公开(公告)日：2012-12-20
申请号：US13517859
申请日：2012-06-14
申请人： Tetsuya Haruna , Masaaki Hirano , Yoshiaki Tamura
发明人： Tetsuya Haruna , Masaaki Hirano , Yoshiaki Tamura
IPC分类号： C03B37/027 , G02B6/02
CPC分类号： C03C3/06 , C03B37/0253 , C03B37/029 , C03B2201/12 , C03B2201/20 , C03B2201/50 , C03B2203/22 , C03B2203/23 , C03B2203/26 , C03B2205/40 , C03B2205/42 , C03C13/045 , C03C2201/11 , C03C2201/12 , C03C2201/50 , G02B6/03627
摘要： There is provided a method for producing an optical fiber having low attenuation, the optical fiber including a core that contains an alkali metal element. An optical fiber preform that includes a core part and a cladding part is drawn with a drawing apparatus to form an optical fiber, the core part having an average concentration of an alkali metal element of 5 atomic ppm or more. During the drawing, the time the temperature of glass is maintained at 1500° C. or higher is 110 minutes or less. The drawing speed is preferably 1200 m/min or more and more preferably 1500 m/min to 2300 m/min. The optical fiber preform preferably has a diameter of 70 mm to 170 mm and more preferably 90 mm to 150 mm.
摘要翻译：提供了一种制造具有低衰减的光纤的方法，该光纤包括含有碱金属元素的芯。包括芯部和包层部的光纤预制棒用拉伸装置拉伸以形成光纤，核部分的碱金属元素的平均浓度为5原子ppm以上。在图中，玻璃的温度保持在1500℃以上的时间为110分钟以下。拉伸速度优选为1200m / min以上，更优选为1500m / min〜2300m / min。光纤预制棒的直径优选为70mm〜170mm，更优选为90mm〜150mm。

27. 发明授权

US08223323B2 Cutoff wavelength measuring method and optical communication system 有权
标题翻译：截止波长测量方法和光通信系统
公开(公告)号：US08223323B2
公开(公告)日：2012-07-17
申请号：US12750029
申请日：2010-03-30
申请人： Tetsuya Nakanishi , Masaaki Hirano , Takashi Sasaki
发明人： Tetsuya Nakanishi , Masaaki Hirano , Takashi Sasaki
IPC分类号： G01N21/00
CPC分类号： G01M11/33
摘要： A method includes a first step of joining a multimode fiber to a first end of an optical fiber being a specimen, allowing light to propagate from the multimode fiber to the specimen, measuring an intensity of light from a second end of the specimen, and determining a first power spectrum; a second step of joining the multimode fiber to a first end of a reference fiber having bending loss higher than that of the specimen, allowing light to propagate from the multimode fiber to the reference fiber, measuring an intensity of light from a second end of the reference fiber, and determining a second power spectrum; a third step of determining a difference spectrum by subtracting the second power spectrum from the first power spectrum; and a fourth step of determining a higher-order mode cutoff wavelength of the specimen on the basis of a shape of the difference spectrum.
摘要翻译：一种方法包括将多模光纤连接到作为样本的光纤的第一端的第一步骤，允许光从多模光纤传播到样品，测量来自样品的第二端的光的强度，以及确定第一功率谱; 将多模光纤连接到具有高于样品的弯曲损耗的参考光纤的第一端的第二步骤，允许光从多模光纤传播到参考光纤，测量来自第二端的光的强度参考光纤，并确定第二功率谱; 第三步骤，通过从第一功率谱中减去第二功率谱来确定差分谱; 以及基于差分光谱的形状来确定样本的高次模截止波长的第四步骤。

28. 发明申请

US20120014654A1 OPTICAL FIBER AND METHOD FOR MANUFACTURING SAME 审中-公开
标题翻译：光纤及其制造方法
公开(公告)号：US20120014654A1
公开(公告)日：2012-01-19
申请号：US13181539
申请日：2011-07-13
申请人： Tetsuya HARUNA , Masaaki Hirano , Nobuhiro Hikichi
发明人： Tetsuya HARUNA , Masaaki Hirano , Nobuhiro Hikichi
IPC分类号： G02B6/028 , C03B37/027 , G02B6/036
CPC分类号： G02B6/03627 , C03B37/02727 , C03B2201/08 , C03B2201/12 , C03B2201/31 , C03B2203/23 , C03B2205/40 , G02B6/0281 , G02B6/03655
摘要： Provided is an optical fiber having a large relative refractive index difference and a reduced transmission loss, as well as a manufacturing method therefor. An optical fiber preform 100, which is made of silica glass as the main element and which includes a core region having a relative refractive index difference of 2.0% or more and less than 3.0% on the basis of the refractive index of pure silica glass and a first cladding region provided around the core region and having a relative refractive index difference of −0.8% or more and less than −0.3% on the basis of the refractive index of pure silica glass, is drawn into a glass fiber. The glass fiber thus drawn is passed through an annealing furnace 21 installed below a drawing furnace 11, whereby the cooling rate of the glass fiber is restrained as compared with the case where it is cooled by air.
摘要翻译：提供一种具有大的相对折射率差和传输损耗降低的光纤及其制造方法。一种由石英玻璃作为主要元件制成的光纤预制件100，其基于纯石英玻璃的折射率和相对折射率差为2.0％以上且小于3.0％的芯区域，将以纯石英玻璃的折射率为基准设置在芯区域周围的相对折射率差为-0.8％以上且小于-0.3％的第一包层区域被拉伸到玻璃纤维中。将如此拉制的玻璃纤维通过安装在拉丝炉11下方的退火炉21，与通过空气冷却的情况相比，玻璃纤维的冷却速度得到抑制。

29. 发明授权

US08076367B2 Benzimidazolylidene propane-1,3-dione derivative or salt thereof 失效
标题翻译：苯并咪唑基丙烷-1,3-二酮衍生物或其盐
公开(公告)号：US08076367B2
公开(公告)日：2011-12-13
申请号：US12726506
申请日：2010-03-18
申请人： Masaaki Hirano , Eiji Kawaminami , Isao Kinoyama , Shunichiro Matsumoto , Kei Ohnuki , Kazuyoshi Obitsu , Toshiyuki Kusayama
发明人： Masaaki Hirano , Eiji Kawaminami , Isao Kinoyama , Shunichiro Matsumoto , Kei Ohnuki , Kazuyoshi Obitsu , Toshiyuki Kusayama
IPC分类号： A01N43/52
CPC分类号： C07D401/06
摘要： Compounds useful as GnRH receptor antagonists are provided. The present inventors have further examined propane-1,3-dione derivatives and confirmed as a result that a propane-1,3-dione having 2-(1,3-dihydro-2H-benzimidazol-2-ylidene), or a compound which has benzene or thiophene ring substituted with a group derived from 1-hydroxymethyl, shows excellent availability, in addition to its excellent GnRH receptor antagonism, thereby accomplishing the invention. Since the compound of the invention shows excellent availability, in addition to its strong GnRH receptor antagonism, it can be expected that it exerts superior drug effect in the living body, and it is useful for the treatment of sex hormone dependent diseases such as prostate cancer, breast cancer, endometriosis, uterine leiomyoma, benign prostatic hypertrophy and the like. In addition, since the compound of the invention is excellent in metabolic stability in human and also is less in drug interaction, it has more desirable properties as a medicament to be used for the aforementioned diseases.
摘要翻译：提供了可用作GnRH受体拮抗剂的化合物。本发明人进一步研究了丙-1,3-二酮衍生物，结果确认了具有2-（1,3-二氢-2H-苯并咪唑-2-亚基）的丙-1,3-二酮或化合物其具有被衍生自1-羟甲基的基团取代的苯或噻吩环，除了其优异的GnRH受体拮抗作用外，显示出优异的可利用性，从而完成本发明。由于本发明的化合物显示出优异的可利用性，除了其强的GnRH受体拮抗作用外，可以预期其在生物体中具有优异的药物作用，并且可用于治疗性激素依赖性疾病如前列腺癌，乳腺癌，子宫内膜异位症，子宫平滑肌瘤，良性前列腺肥大等。此外，由于本发明的化合物在人体中的代谢稳定性优异，药物相互作用也较少，因此作为上述疾病的药物具有更优选的特性。

30. 发明申请

US20100247093A1 CUTOFF WAVELENGTH MEASURING METHOD AND OPTICAL COMMUNICATION SYSTEM 有权
标题翻译：切割波长测量方法和光通信系统
公开(公告)号：US20100247093A1
公开(公告)日：2010-09-30
申请号：US12750029
申请日：2010-03-30
申请人： Tetsuya Nakanishi , Masaaki Hirano , Takashi Sasaki
发明人： Tetsuya Nakanishi , Masaaki Hirano , Takashi Sasaki
IPC分类号： H04B10/08 , G01N21/00
CPC分类号： G01M11/33
摘要： A method includes a first step of joining a multimode fiber to a first end of an optical fiber being a specimen, allowing light to propagate from the multimode fiber to the specimen, measuring an intensity of light from a second end of the specimen, and determining a first power spectrum; a second step of joining the multimode fiber to a first end of a reference fiber having bending loss higher than that of the specimen, allowing light to propagate from the multimode fiber to the reference fiber, measuring an intensity of light from a second end of the reference fiber, and determining a second power spectrum; a third step of determining a difference spectrum by subtracting the second power spectrum from the first power spectrum; and a fourth step of determining a higher-order mode cutoff wavelength of the specimen on the basis of a shape of the difference spectrum.
摘要翻译：一种方法包括将多模光纤连接到作为样本的光纤的第一端的第一步骤，允许光从多模光纤传播到样品，测量来自样品的第二端的光的强度，以及确定第一功率谱; 将多模光纤连接到具有高于样品的弯曲损耗的参考光纤的第一端的第二步骤，允许光从多模光纤传播到参考光纤，测量来自第二端的光的强度参考光纤，并确定第二功率谱; 第三步骤，通过从第一功率谱中减去第二功率谱来确定差分谱; 以及基于差分光谱的形状来确定样本的高次模截止波长的第四步骤。

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