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21. 发明授权

US07283213B2 Method and system to correct motion blur and reduce signal transients in time-of-flight sensor systems 有权
标题翻译：纠正运动模糊和降低飞行时间传感器系统信号瞬变的方法和系统
公开(公告)号：US07283213B2
公开(公告)日：2007-10-16
申请号：US11350222
申请日：2006-02-08
申请人： Patrick O'Connor , Ilhami Torunoglu , Rajeev Nagabhirana
发明人： Patrick O'Connor , Ilhami Torunoglu , Rajeev Nagabhirana
IPC分类号： G01C3/08
CPC分类号： G01C3/08 , G01S17/89
摘要： TOF system shutter time needed to acquire image data in a time-of-flight (TOF) system that acquires consecutive images is reduced, thus decreasing the time in which relative motion can occur. In one embodiment, pixel detectors are clocked with multi-phase signals and integration of the four signals occurs simultaneously to yield four phase measurements from four pixel detectors within a single shutter time unit. In another embodiment, phase measurement time is reduced by a factor (1/k) by providing super pixels whose collection region is increased by a factor “k” relative to a normal pixel detector. Each super pixel is coupled to k storage units and four-phase sequential signals. Alternatively, each pixel detector can have k collector regions, k storage units, and share common clock circuitry that generates four-phase signals. Various embodiments can reduce the mal-effects of clock signal transients upon signals, and can be dynamically reconfigured as required.
摘要翻译：在获取连续图像的飞行时间（TOF）系统中获取图像数据所需的TOF系统快门时间减少，从而减少相对运动发生的时间。在一个实施例中，通过多相信号对像素检测器进行时钟控制，并且四个信号的积分同时发生，以在单个快门时间单位内从四个像素检测器产生四相测量。在另一个实施例中，通过提供相对于正常像素检测器的收集区域增加因子“k”的超像素，将相位测量时间减小因子（1 / k）。每个超像素耦合到k个存储单元和四个相序的信号。或者，每个像素检测器可以具有k个集电极区域，k个存储单元，以及共享产生四相信号的公共时钟电路。各种实施例可以减少对信号的时钟信号瞬变的不良影响，并且可以根据需要动态地重新配置。

22. 发明申请

US20070061728A1 Time approximation for text location in video editing method and apparatus 审中-公开
标题翻译：视频编辑方法和设备中文本位置的时间近似
公开(公告)号：US20070061728A1
公开(公告)日：2007-03-15
申请号：US11516458
申请日：2006-09-05
申请人： Leonard Sitomer , Patrick O'Connor , Stephen Reber
发明人： Leonard Sitomer , Patrick O'Connor , Stephen Reber
IPC分类号： G11B27/00 , G10L21/00
CPC分类号： G11B27/034 , G06F16/7844 , G10L15/26 , G11B27/031 , G11B27/28 , G11B27/322 , G11B27/34
摘要： A time approximator for use in video editing is disclosed. The time approximator estimates time location in the media file/video data domain of a user-selected word or text unit in the text script transcription of the corresponding audio of the video data. During video editing, the time approximator calculates and displays the estimated time location of user-selected text to assist the user-editor in cross referencing between the beginning and ending of user-selected passage statements in the text script and the corresponding video data in a rough cut or subsequent video data work. The time approximator enables simultaneous editing of text and video by the selection of either source component.
摘要翻译：公开了用于视频编辑的时间近似器。时间逼近器估计在视频数据的相应音频的文本脚本转录中用户选择的单词或文本单元的媒体文件/视频数据域中的时间位置。在视频编辑期间，时间逼近器计算并显示用户选择的文本的估计时间位置，以帮助用户编辑器在文本脚本中的用户选择的段落语句的开始和结束之间进行交叉引用，以及相应的视频数据粗切或后续视频数据工作。时间逼近器可以通过选择任何一个源组件来同时编辑文本和视频。

23. 发明申请

US20060116711A1 Embolic coils 有权
公开(公告)号：US20060116711A1
公开(公告)日：2006-06-01
申请号：US11000741
申请日：2004-12-01
申请人： Christopher Elliott , Patrick O'Connor
发明人： Christopher Elliott , Patrick O'Connor
IPC分类号： A61M29/00
CPC分类号： A61B17/1215 , A61B17/12022 , A61B17/12113 , A61B17/12145
摘要： Embolic coils, as well as related methods, devices, and compositions, are disclosed.

24. 发明授权

US06670167B1 Catalytic domain of the human effector cell cycle checkpoint protein kinase materials and methods for identification of inhibitors thereof 失效
标题翻译：人效应细胞周期检查点蛋白激酶材料的催化结构域及其抑制剂的鉴定方法
公开(公告)号：US06670167B1
公开(公告)日：2003-12-30
申请号：US09460421
申请日：1999-12-14
申请人： Ping Chen , Mark Anderson , Ya-Li Deng , Smita Gaur , Chen Chen Kan , Chun Luo , Karen Lundgren , Stephen Margosiak , Binh Nguyen , Patrick O'Connor , James Register , Anna Tempczyk Russell , Jay Sarup
发明人： Ping Chen , Mark Anderson , Ya-Li Deng , Smita Gaur , Chen Chen Kan , Chun Luo , Karen Lundgren , Stephen Margosiak , Binh Nguyen , Patrick O'Connor , James Register , Anna Tempczyk Russell , Jay Sarup
IPC分类号： C07H2104
CPC分类号： C12N9/1205 , C12Q1/34
摘要： The present invention relates to the identification, isolation and purification of the catalytic domain of the human effector checkpoint protein kinase (hChk1). A 1.7Å crystal structure of the hChk1 kinase domain in the active conformation is reported herein. The kinase domain of hChk1 and its associated crystal structure is described for use in the discovery, identification and characterization of inhibitors of hChk1. This structure provides a three-dimensional description of the binding site of the hChk1 for structure-based design of small molecule inhibitors thereof as therapeutic agents. Inhibitors of hChk1 find utility in the treatment of hyperproliferative disorders such as HIV and cancer.
摘要翻译：本发明涉及人类效应子检测点蛋白激酶（hChk1）的催化结构域的鉴定，分离和纯化。本文报道了活性构象中hChk1激酶结构域的1.7Å晶体结构。描述了hChk1的激酶结构域及其相关晶体结构，用于hChk1抑制剂的发现，鉴定和表征。该结构提供了hChk1的结合位点的三维描述，用于其作为治疗剂的小分子抑制剂的基于结构的设计。 hChk1的抑制剂可用于治疗过度增生性疾病如艾滋病毒和癌症。

25. 发明授权

US09103210B2 Rotary device 有权
标题翻译：旋转装置
公开(公告)号：US09103210B2
公开(公告)日：2015-08-11
申请号：US13379526
申请日：2010-07-01
申请人： Patrick O'Connor
发明人： Patrick O'Connor
IPC分类号： F02B53/00 , F01C1/18 , F01C1/24 , F04C18/00 , F01B13/06 , F01C1/08
CPC分类号： F01C1/18 , F01B13/067 , F01C1/084
摘要： A rotary device is described for use in a rotary engine, or a compressor, or turbine, the rotary device comprising two rotors disposed adjacent each other and rotatable about substantially parallel axes of rotation. Each of the rotors has protrusions extending therefrom at regular intervals about the circumference of each to define an open portion of a sealable compression chamber between adjacent protrusions. Each protrusion has two side surfaces and a projecting end surface, wherein the meeting point between each side surface and the projecting end surface defines a tip. The two rotors are arranged such that upon contra rotation of the rotors, a protrusion of one of the rotors engages between a pair of protrusions on the other rotor, and the tips of the engaging rotor are in constant sealing contact with the opposing side surfaces of the pair of protrusions for a predetermined period of time. During the predetermined period of time, a sealed chamber is formed and the volume of the chamber is reduced to a predetermined level by the contra rotation.
摘要翻译：描述了用于旋转发动机或压缩机或涡轮机中的旋转装置，该旋转装置包括彼此相邻设置并可大致平行的旋转轴线旋转的两个转子。每个转子具有从其周围以规则的间隔延伸的突起，每个圆周围绕相邻的突起之间限定可密封的压缩室的开口部分。每个突起具有两个侧表面和一个突出端表面，其中每个侧表面与突出端表面之间的汇合点限定一个尖端。两个转子被布置成使得当转子反转时，一个转子的突起接合在另一个转子上的一对突起之间，并且接合转子的末端与相对的侧表面保持恒定的密封接触该一对突起预定的时间段。在预定时间期间，形成密封室，并且通过反向旋转将室的体积减小到预定水平。

26. 发明申请

US20140221374A1 RAF KINASE INHIBITORS 审中-公开
标题翻译： RAF激酶抑制剂
公开(公告)号：US20140221374A1
公开(公告)日：2014-08-07
申请号：US14005720
申请日：2012-03-16
申请人： Jean-Michel Vernier , Stephanie Hopkins , Pierre-Yves Bounaud , Patrick O'Connor , David Matthews , Steve Bender
发明人： Jean-Michel Vernier , Stephanie Hopkins , Pierre-Yves Bounaud , Patrick O'Connor , David Matthews , Steve Bender
IPC分类号： C07D417/14 , C07D403/14 , C07D401/14 , C07D401/04 , C07D403/04 , C07D417/04
CPC分类号： C07D417/14 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D417/04 , C07D471/04
摘要： Described herein are compounds, pharmaceutical compositions and methods for the inhibition of RAF kinase mediated signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human disease and disorders.
摘要翻译：本文描述了用于抑制RAF激酶介导的信号传导的化合物，药物组合物和方法。所述化合物，药物组合物和方法可用于治疗人类疾病和病症。

27. 发明申请

US20070081878A1 Combined baler/bale wrapper 有权
标题翻译：打包机/包装机组合打包机
公开(公告)号：US20070081878A1
公开(公告)日：2007-04-12
申请号：US10472399
申请日：2002-03-22
申请人： Padraic McHale , Martin McHale , James Heaney , Gerard Sheridan , Patrick O'Connor , John Biggins
发明人： Padraic McHale , Martin McHale , James Heaney , Gerard Sheridan , Patrick O'Connor , John Biggins
IPC分类号： A01D85/00
CPC分类号： A01F15/071 , A01D39/005 , A01D59/00 , A01F15/07 , A01F15/0715 , A01F15/0883 , A01F2015/0735 , A01F2015/074 , A01F2015/0775 , B65B11/04 , B65B13/00 , B65B45/00
摘要： A combined baler/bale wrapper (1) comprises a chassis (5) on which a baler (10) and a bale wrapper (11) are mounted. The baler (10) comprises a stationary segment (18), a lower segment (19) and an upper segment (20) all of which carry bale forming rollers (25) which define a bale forming chamber (15) within which a round bale (2) is formed. The lower segment (19) and the upper segment (20) are pivotal about first and second pivot axes (35,40), respectively from a bale forming position (FIG. 5) to a discharge position (FIG. 1) for transferring a bale upwardly rearwardly from of the bale forming chamber (15) directly onto first and second bale supporting rollers (50) of the bale wrapper (11). The bale supporting rollers (50) rotate the bale (2) about a first wrapping axis (53) while a carrier ring (55) simultaneously revolves a pair of wrapping material dispensers (54) about a second horizontal wrapping axis (56) for dispensing wrapping material onto the bale (2) for wrapping thereof. The combined baler/bale wrapper is efficient, compact and of minimum length.
摘要翻译：组合打捆机/捆包装机（1）包括底盘（5），捆扎机（10）和捆包装机（11）安装在该底盘上。打捆机（10）包括固定部分（18），下部部分（19）和上部部分（20），所有这些部分都带有限定了捆包形成室（15）的捆捆成形辊（25）（2）。下段（19）和上段（20）分别围绕第一和第二枢转轴线（35,40）枢转，分别从捆包形成位置（图5）到排出位置（图1），用于转移从捆包形成室（15）向后向上直接包装到捆包装（11）的第一和第二捆包支承辊（50）上。捆包支撑辊（50）围绕第一包裹轴线（53）旋转捆包（2），而承载环（55）同时围绕第二水平包裹轴线（56）旋转一对包装材料分配器（54），用于分配将包装材料包裹在捆包（2）上以将其包裹。组合式打捆机/捆包机是高效，紧凑且最小长度的。

28. 发明申请

US20060292535A1 DISEASE TREATMENT SIMULATION 审中-公开
标题翻译：疾病治疗模拟
公开(公告)号：US20060292535A1
公开(公告)日：2006-12-28
申请号：US11379351
申请日：2006-04-19
申请人： Patrick O'Connor , George Biltz , Pradyumna (Autri) Dutta , Paul Johnson , William Rush , JoAnn Sperl-Hillen
发明人： Patrick O'Connor , George Biltz , Pradyumna (Autri) Dutta , Paul Johnson , William Rush , JoAnn Sperl-Hillen
IPC分类号： G09B23/28
CPC分类号： G09B23/28 , G09B7/00 , G09B19/00
摘要： A method of dynamically simulating a physician assessment and teaching environment for treatment of a chronic illness is provided. The method includes providing a library of patient cases histories, selecting a patient case history from the library of patient case histories, providing a treatment action in response to the particular patient case history selected, and providing a projection of the patient's future clinical status based upon the treatment action provided.
摘要翻译：提供了一种动态模拟用于治疗慢性疾病的医师评估和教学环境的方法。该方法包括提供患者病例历史库，从患者病史记录库选择患者病历，提供响应于所选择的特定患者病史的治疗动作，以及基于以下方式提供患者未来临床状态的预测：提供治疗行动。

29. 发明授权

US06546190B1 Synchronization of multiple media streams 失效
标题翻译：多媒体流的同步
公开(公告)号：US06546190B1
公开(公告)日：2003-04-08
申请号：US09064477
申请日：1998-04-22
申请人： Michael E. Phillips , Patrick O'Connor , Eric Peters
发明人： Michael E. Phillips , Patrick O'Connor , Eric Peters
IPC分类号： H04N591
CPC分类号： G11B27/031 , G11B27/002 , G11B27/06 , G11B27/10 , G11B27/11 , G11B27/24 , G11B27/323 , G11B2220/20 , G11B2220/90 , H04N5/85 , H04N5/926 , H04N5/9265 , H04N5/9267
摘要： A method of synchronizing digitized audio information and digitized picture information establishes a reference time base based on timecodes included with the audio and picture information. The reference time base may be used to synchronize output between a digitized source and one which may be digitized or undigitized.
摘要翻译：使数字化音频信息和数字化图像信息同步的方法基于音频和图像信息中包含的时间码来建立参考时基。参考时基可用于同步数字化源与可能被数字化或未编码的源之间的输出。

30. 发明授权

US5745637A Synchronization of digital video with digital audio 失效
公开(公告)号：US5745637A
公开(公告)日：1998-04-28
申请号：US713107
申请日：1996-09-16
申请人： Michael E. Phillips , Patrick O'Connor , Eric Peters
发明人： Michael E. Phillips , Patrick O'Connor , Eric Peters
IPC分类号： H04N5/78 , G11B27/00 , G11B27/031 , G11B27/06 , G11B27/10 , G11B27/11 , G11B27/24 , G11B27/32 , H04N5/85 , H04N5/926 , H04N5/928 , H04N5/91
CPC分类号： G11B27/031 , G11B27/002 , G11B27/06 , G11B27/10 , G11B27/11 , G11B27/24 , G11B27/323 , H04N5/926 , H04N5/9267 , G11B2220/20 , G11B2220/90 , H04N5/85 , H04N5/9265
摘要： A method of synchronizing digitized audio information and digitized picture information establishes a reference time base based on timecodes included with the audio and picture information. The reference time base may be used to synchronize output between a digitized source and one which may be digitized or undigitized.

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