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21. 发明申请

US20120142641A1 TARGETTED DRUG DELIVERY TO THE BONE 有权
标题翻译：目标药物递送到骨头
公开(公告)号：US20120142641A1
公开(公告)日：2012-06-07
申请号：US13375713
申请日：2010-06-07
申请人： Subramanian Venkatraman , Say Chye Joachim Loo
发明人： Subramanian Venkatraman , Say Chye Joachim Loo
IPC分类号： A61K31/663 , C07F5/00 , C07F13/00 , A61P5/18 , A61P19/10 , A61P35/04 , A61P35/00 , C07F9/38 , A61P19/08
CPC分类号： A61K47/48861 , A61K47/48015 , A61K47/52 , A61K47/6923 , C07B2200/11 , C07F9/386 , C07F9/3869 , C07F9/3873
摘要： The present invention relates to a complex of a bisphosphonate compound, methods of preparing such complex and uses thereof.
摘要翻译：本发明涉及双膦酸盐化合物的配合物，制备这种络合物的方法及其应用。

22. 发明授权

US08011870B2 Multi level automated car parking system 失效
标题翻译：多级自动停车系统
公开(公告)号：US08011870B2
公开(公告)日：2011-09-06
申请号：US12066417
申请日：2006-09-11
申请人： Subramanian Venkatraman , Venkatraman Guruprasad
发明人： Subramanian Venkatraman , Venkatraman Guruprasad
IPC分类号： E04H6/12
CPC分类号： E04H6/24
摘要： A structure having floors for receiving and delivery of cars, and parking floors. Receiving and delivery floors have slat conveyors with platform carriers placed in slots in the conveyor. Cars are parked by patrons on the platform carriers. After the patron exits the car the conveyor conveys the carrier on which the car is parked to the front of an elevator. A power arm in the elevator draws the carrier into the elevator, and the elevator rises to a parking floor. On the parking floor the elevator power arm pushes the platform carrier with the car on top onto a waiting transfer module, which moves laterally to the front of an allotted parking slot. A power arm on the transfer module pushes the platform carrier with the car on top into the parking slot. Upon the patron's return the car is retrieved as described above but in reverse order.
摘要翻译：具有用于接收和运送汽车的地板的结构以及停车地板。接收和交付地板具有板式输送机，其中平台载体放置在输送机中的槽中。汽车由乘客在乘客平台上停放。在顾客离开汽车后，输送机将停放在汽车上的行李架传送到电梯的前方。电梯中的动力臂将载体拉入电梯，升降机上升到停车场。在停车场上，电梯的动力臂将车顶上的轿厢推到等待的转移模块上，等待的转移模块横向移动到分配的停车位的前部。传输模块上的电源臂将车载平台托架顶部推入停车位。在顾客返回时，如上所述检索汽车，但是以相反的顺序。

23. 发明申请

US20080097620A1 IMPLANTABLE ARTICLE, METHOD OF FORMING SAME AND METHOD FOR REDUCING THROMBOGENICITY 审中-公开
标题翻译：可植入物，其形成方法和降低致血性的方法
公开(公告)号：US20080097620A1
公开(公告)日：2008-04-24
申请号：US11753878
申请日：2007-05-25
申请人： Subramanian Venkatraman , Yin Chiang Boey
发明人： Subramanian Venkatraman , Yin Chiang Boey
IPC分类号： A61F2/02
CPC分类号： A61F2/0077 , A61F2/06 , A61F2210/0004 , A61L27/18 , A61L27/34 , A61L27/50 , A61L27/56 , A61L27/58 , A61L29/08 , A61L31/08 , A61L31/10 , A61L33/0011 , A61L2400/18 , A61L2420/06 , A61L2420/08 , C08L67/04
摘要： Endothelialization of a bodily fluid or tissue-contacting, particularly blood-contacting, surface may be accomplished to render that surface substantially non-thrombogenic. Thrombosis may also be mitigated or eliminated by providing an eroding layer on the surface that results in the removal of any thrombus formation as the layer erodes. An implantable device may utilize at least one surface having a plurality of nano-craters thereon that enhance or promote endothelialization. Additionally, an implantable device may have at least one first degradable layer for contacting bodily fluid or tissue and disposed about a central core, and at least one second degradable layer between the first degradable layer and the central core. The first degradable layer has a first degradation rate and the second degradable layer has a second degradation rate which degrades more slowly than the first degradable layer on contact with bodily fluid or tissue.
摘要翻译：可以实现体液或组织接触，特别是与血液接触的表面的内皮化，以使该表面基本上非血栓形成。也可以通过在表面上提供侵蚀层来减轻或消除血栓形成，从而导致随着层侵蚀而去除任何血栓形成。可植入装置可以利用其上具有多个纳米凹坑的至少一个表面，其增强或促进内皮化。另外，可植入装置可以具有用于接触体液或组织的至少一个第一可降解层，并且围绕中心芯设置，以及在第一可降解层和中心芯之间的至少一个第二可降解层。第一可降解层具有第一降解速率，并且第二可降解层具有在与体液或组织接触时比第一可降解层更缓慢地降解的第二降解速率。

24. 发明申请

US20050048104A1 Transdermal drug delivery devices comprising a polyurethane drug reservoir 审中-公开
标题翻译：包含聚氨酯药物储库的透皮药物递送装置
公开(公告)号：US20050048104A1
公开(公告)日：2005-03-03
申请号：US10611531
申请日：2003-06-30
申请人： Subramanian Venkatraman , Thomas Stein , James Snider , Richard Hamlin
发明人： Subramanian Venkatraman , Thomas Stein , James Snider , Richard Hamlin
IPC分类号： A61K9/70 , A61K31/138 , A61K31/216 , A61K31/4468 , A61K47/14 , A61K47/18 , A61K47/34 , A61P1/00 , A61P1/04 , A61P3/02 , A61P3/10 , A61P5/06 , A61P5/26 , A61P5/38 , A61P7/02 , A61P7/04 , A61P9/08 , A61P9/10 , A61P11/06 , A61P15/00 , A61P23/00 , A61P25/16 , A61P25/24 , A61P25/30 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/00 , A61P35/00 , A61P37/08 , A61P43/00 , C08G18/48 , C08G18/65 , C08G18/75 , C08K5/00 , C08L75/04
CPC分类号： A61K9/7069 , A61K9/7084 , A61K47/34
摘要： The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.
摘要翻译：本发明涉及透皮药物递送领域。更具体地，本发明涉及用于透皮药物递送装置的药物储存材料。本发明的药物储存器包含聚氨酯聚合物，其可以在低于导致温度敏感性药物和/或赋形剂降解的温度下进行加工。本发明还涉及定制聚氨酯材料的释放特性以适应从透皮药物递送装置递送的一定范围的合适药物和/或为特定药物提供一定范围的递送速率。

25. 发明申请

US20050021131A1 Polymeric stent and method of manufacture 审中-公开
标题翻译：聚合物支架及其制造方法
公开(公告)号：US20050021131A1
公开(公告)日：2005-01-27
申请号：US10867617
申请日：2004-06-15
申请人： Subramanian Venkatraman , Yin Boey
发明人： Subramanian Venkatraman , Yin Boey
IPC分类号： A61F2/82 , A61F2/88 , B29C47/06 , A61F2/06
CPC分类号： A61F2/88 , A61F2/82 , A61F2210/0076 , A61L31/04 , A61L31/14 , Y10T156/10
摘要： A stent formed of polymeric material, useful for the expansion of a lumen and the delivery of one or more therapeutic agents in situ is disclosed. The stent may be multi-layered, and may change shape at a state transition temperature governed by the materials forming the layers. Methods of use and manufacture are also disclosed.
摘要翻译：公开了一种由聚合材料形成的支架，其可用于扩张内腔和原位递送一种或多种治疗剂。支架可以是多层的，并且可以在由形成层的材料控制的状态转变温度下改变形状。还公开了使用和制造方法。

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