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21. 发明授权

US4614613A Preparation of .beta.-N-aziridinopropionates 失效
标题翻译：制备β-N-氮丙啶丙酸酯
公开(公告)号：US4614613A
公开(公告)日：1986-09-30
申请号：US628773
申请日：1984-07-09
申请人： Rolf Fikentscher , Siegfried Schneider , Erhard Klahr , Friedrich Reinert , Gunter Eckert , Adolf Stuebinger
发明人： Rolf Fikentscher , Siegfried Schneider , Erhard Klahr , Friedrich Reinert , Gunter Eckert , Adolf Stuebinger
IPC分类号： B01J31/12 , C07B61/00 , C07D203/08
CPC分类号： C07D203/08
摘要： .beta.-N-aziridinopropionates of relatively high boiling alcohols or polyalcohols are prepared by transesterifying a .beta.-N-aziridinopropionate of a lower alcohol of 1 to 4 carbon atoms with a relatively high boiling alcohol or polyalcohol by a process in which the transesterification is carried out in the presence of, as a transesterification catalyst, a titanium(IV) or tin(IV) compound which is soluble in an organic medium.
摘要翻译：相对高沸点的醇或多元醇的β-N-吖丙啶丙酸酯通过一种具有1-4个碳原子的低级醇的β-N-氮丙啶基丙酸酯与相对高沸点醇或多元醇的酯交换反应来制备在作为酯交换催化剂存在下，可溶于有机介质的钛（IV）或锡（IV）化合物。

22. 发明授权

US4443742A Phase locked loop motor control system 失效
标题翻译：锁相环电机控制系统
公开(公告)号：US4443742A
公开(公告)日：1984-04-17
申请号：US326070
申请日：1981-11-30
申请人： Siegfried Schneider
发明人： Siegfried Schneider
IPC分类号： G03B27/34 , G03B27/50 , G03B27/52 , G03G15/04 , G03G15/043 , H02P5/52 , H02P29/00 , G05B1/06
CPC分类号： G03B27/525 , Y10S388/911 , Y10S388/915
摘要： A phase locked loop control system, in particular for use for synchronizing the operation of a carriage drive motor and a main drive motor in a photocopier, uses a digital frequency- and phase-comparator and relies on the output pulses, used to power the slaved motor, being shaped so that each positive-going d.c. drive pulse is followed by a negative-going d.c. braking pulse of smaller amplitude, to provide positive registration of the slaved motor with the pulsed driving signal.
摘要翻译：特别是用于使复印机中的托架驱动电动机和主驱动电动机的操作同步的锁相环控制系统使用数字频率和相位比较器，并且依赖于输出脉冲，用于为从动装置提供动力电机，形状使每个正向直流驱动脉冲之后是负向的直流。制动脉冲幅度较小，提供从动电机与脉冲驱动信号的正对准。

23. 发明授权

US4426149A Photocopier scanning drive system 失效
标题翻译：复印机扫描驱动系统
公开(公告)号：US4426149A
公开(公告)日：1984-01-17
申请号：US326063
申请日：1981-11-30
申请人： Klaus Kuemmel , Gerhard Klapettek , Siegfried Schneider
发明人： Klaus Kuemmel , Gerhard Klapettek , Siegfried Schneider
IPC分类号： G03B27/34 , G03B27/50 , G03B27/52 , G03G15/04 , G03G15/043 , H02P5/52 , H02P29/00 , G03G15/00
CPC分类号： G03B27/525 , Y10S388/911 , Y10S388/915
摘要： A photocopier scanning system has a scanning member (which may be the scanning lamp, a scanning mirror, a scanning slit, or a document carrier) on a scanning system powered by a d.c. drive motor synchronized to the rotation of the a.c. main drive motor for the other components of the photocopier. A variable programmer using a phase locked loop control circuit including pulse encoders slaved to the motors maintains strict synchronization between the scanning drive motor and the main drive motor with an appropriate proportionality dependent upon the image magnification/reduction ratio of the photocopier. The optical system may include a movable zoom lens element which gives infinitely variable selection of the magnification/reduction ratio, and which can readily be connected to the programmer to achieve an infinitely variable proportionality between the speeds of the scanning drive motor and the main drive motor to suit any such magnification/reduction ratio. Also the output of the exposure lamp is variable in accordance with the magnification/reduction ratio.
摘要翻译：复印机扫描系统在由直流电源供电的扫描系统上具有扫描构件（其可以是扫描灯，扫描镜，扫描狭缝或文档载体）。驱动电机同步旋转a.c. 复印机其他部件的主驱动电机。使用包括从动电机的脉冲编码器的锁相环控制电路的可变编程器根据复印机的图像倍率/缩小率，以适当的比例来保持扫描驱动马达与主驱动马达之间的严格同步。该光学系统可以包括一个可移动的变焦透镜元件，它可以无级地选择放大/缩小比率，并且可以容易地连接到编程器，以实现扫描驱动马达和主驱动马达的速度之间的无级变比比例以适应任何这种放大/缩小比例。此外，曝光灯的输出也可以根据放大率/缩小率而变化。

24. 发明授权

US08815855B2 N-sulphonylpyrroles and their use as histone deacetylase inhibitors 有权
标题翻译： N-磺酰基吡咯及其作为组蛋白脱乙酰酶抑制剂的用途
公开(公告)号：US08815855B2
公开(公告)日：2014-08-26
申请号：US12628690
申请日：2009-12-01
申请人： Thomas Maier , Thomas Bär , Thomas Beckers , Astrid Zimmermann , Siegfried Schneider , Volker Gekeler
发明人： Thomas Maier , Thomas Bär , Thomas Beckers , Astrid Zimmermann , Siegfried Schneider , Volker Gekeler
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/4439 , A61K31/4155 , C07D409/12 , C07D207/48 , C07D409/14 , C07D401/12 , C07D413/12 , C07D417/14 , C07D403/12 , C07D405/12
CPC分类号： C07D403/12 , C07D207/48 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/14
摘要： Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
摘要翻译：其中R 1，R 2，R 3，R 4，R 5，R 6和R 7具有说明书中所示含义的某种式（I）的化合物是新的有效的HDAC抑制剂。

25. 发明授权

US08529446B2 Methods for determining parameters and planning clinical studies in automatic study and data management systems 有权
标题翻译：在自动研究和数据管理系统中确定参数和规划临床研究的方法
公开(公告)号：US08529446B2
公开(公告)日：2013-09-10
申请号：US11806335
申请日：2007-05-31
申请人： Markus Schmidt , Siegfried Schneider , Gudrun Zahlmann
发明人： Markus Schmidt , Siegfried Schneider , Gudrun Zahlmann
IPC分类号： A61B5/00 , A61B5/05 , G06K9/62 , G06F17/00 , G06N5/00 , G06N5/02
CPC分类号： G16H10/20 , G06F19/00 , G16H10/60
摘要： In a method for determining a parameter in an automatic study and data management system, data is gathered in a knowledge database, and a parameter is determined based the data gathered in the knowledge database. The data is correlated to at least one of a configuration and implementation of a previous clinical study. The parameter is usable for configuring a future clinical study.
摘要翻译：在用于确定自动研究和数据管理系统中的参数的方法中，数据被收集在知识数据库中，并且基于在知识数据库中收集的数据确定参数。数据与先前临床研究的配置和实施中的至少一个相关。该参数可用于配置未来的临床研究。

26. 发明申请

US20080194921A1 Methods and systems for automatically evaluating data from at least one clinical study 审中-公开
标题翻译：至少一项临床研究自动评估数据的方法和系统
公开(公告)号：US20080194921A1
公开(公告)日：2008-08-14
申请号：US11806336
申请日：2007-05-31
申请人： Markus Schmidt , Siegfried Schneider , Gudrun Zahlmann
发明人： Markus Schmidt , Siegfried Schneider , Gudrun Zahlmann
IPC分类号： A61B5/00
CPC分类号： G16H10/60 , G16H10/20
摘要： In a method for automatically evaluating data from at least one clinical study, data may be assessed at a study management system based on at least one management criteria. At least one measured variable may be determined based on the assessed data, and at least one action correlated to at least one facility may be initiated based on the at least one measured variable. The at least one management criteria may be associated with the at least one clinical study.
摘要翻译：在用于自动评估来自至少一项临床研究的数据的方法中，可以基于至少一个管理标准在研究管理系统评估数据。可以基于评估的数据来确定至少一个测量变量，并且可以基于至少一个测量变量来启动与至少一个设施相关的至少一个动作。所述至少一个管理标准可以与所述至少一个临床研究相关联。

27. 发明申请

US20080176848A1 N-Sulphonylpyrroles and Their Use as Histone Deacetylase Inhibitors 有权
标题翻译： N-磺酰吡喃并用作组蛋白脱乙酰酶抑制剂
公开(公告)号：US20080176848A1
公开(公告)日：2008-07-24
申请号：US11885832
申请日：2006-03-14
申请人： Thomas Maier , Thomas Bar , Thomas Beckers , Astrid Zimmermann , Siegfried Schneider , Volker Gekeler
发明人： Thomas Maier , Thomas Bar , Thomas Beckers , Astrid Zimmermann , Siegfried Schneider , Volker Gekeler
IPC分类号： C07D207/48 , C07D401/12 , C07D403/12 , C07D409/14 , C07D413/12 , C07D401/14 , A61K31/404 , A61K31/4155 , A61K31/4439 , A61K31/40 , A61K31/4025 , A61P35/00
CPC分类号： C07D403/12 , C07D207/48 , C07D401/12 , C07D405/12 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/14
摘要： Compounds of a certain formula (I) in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors.
摘要翻译：其中R 1，R 2，R 3，R 4，R 5，R 6和R 7具有说明书中所示含义的某种式（I）的化合物是新的有效的HDAC抑制剂。

28. 发明授权

US07283653B2 Method and system for supporting the evaluation of a picture of an eye 有权
标题翻译：支持对眼睛图像进行评估的方法和系统
公开(公告)号：US07283653B2
公开(公告)日：2007-10-16
申请号：US10305036
申请日：2002-11-26
申请人： Gudrun Zahlmann , Volker Schmidt , Siegfried Schneider
发明人： Gudrun Zahlmann , Volker Schmidt , Siegfried Schneider
IPC分类号： G06K9/00
CPC分类号： A61B3/12 , A61B5/14532
摘要： In a method and a system for supporting the evaluation of a picture of a patient's eye the picture is displayed on a screen. An image-processing algorithm from a number of image processing algorithms is selected due to a preliminary diagnosis selected from a number of diagnoses which are related to diabetes. Each image-processing algorithm of the number of image processing algorithms is associated with a diagnosis of the number of diagnoses and is designed to search for a pattern which is specific to the respective diagnosis. The selected image-processing algorithm then is applied to the picture and a pattern which is detected by the selected image-processing algorithm is marked on the screen in the picture.
摘要翻译：在用于支持对患者眼睛的图像的评估的方法和系统中，图像显示在屏幕上。由于从与糖尿病相关的许多诊断中选出的初步诊断，选择了许多图像处理算法的图像处理算法。图像处理算法的数量的每个图像处理算法与诊断次数的诊断相关联，并且被设计为搜索特定于相应诊断的模式。然后将所选择的图像处理算法应用于图像，并且在图像的屏幕上标记由所选择的图像处理算法检测的图案。

29. 发明授权

US07066883B2 Method and system for monitoring the course of therapy of a patient being therapeutically treated 有权
标题翻译：用于监测被治疗的患者的治疗过程的方法和系统
公开(公告)号：US07066883B2
公开(公告)日：2006-06-27
申请号：US10139834
申请日：2002-05-07
申请人： Volker Schmidt , Siegfried Schneider , Sven Tiffe
发明人： Volker Schmidt , Siegfried Schneider , Sven Tiffe
IPC分类号： A61B5/00
CPC分类号： G06F19/3418 , A61B5/14532 , G06F19/00 , G06F19/324 , G06F19/3481 , G16H40/63 , G16H50/20 , G16H50/30 , Y10S128/92
摘要： In a method and system for monitoring the course of therapy administered to a patient, at least one information value that requires a therapeutic and/or diagnostic measure and that is a direct or indirect measure of the course of the therapy is registered continuously or in time intervals, and at least one comparison value, to be compared to the information value or to a calculated value determined based on the information value, is allocated to the information value. An alarm signal is emitted given an impermissible deviation of the information value or of the calculated value from the comparison value and is detected in the course of the comparison. The comparison value is varied dependent on the course of the therapy and is adapted to the course of the therapy, the adaptation of ensuing automatically or by means of an authorized person or entity.
摘要翻译：在用于监测施用于患者的治疗过程的方法和系统中，需要持续或及时注册至少一个需要治疗和/或诊断测量并且是治疗过程的直接或间接测量的信息值间隔以及与信息值进行比较的至少一个比较值或基于信息值确定的计算值被分配给信息值。由于信息值或计算值与比较值不一致的偏差，所以在比较过程中检测到报警信号。比较值根据治疗过程而变化，并适应治疗过程，自动适应或通过授权人员或实体的适应。

30. 发明授权

US07020235B2 Method for generating a volume dataset 有权
标题翻译：生成卷数据集的方法
公开(公告)号：US07020235B2
公开(公告)日：2006-03-28
申请号：US10651364
申请日：2003-08-29
申请人： Joachim Hornegger , Siegfried Schneider
发明人： Joachim Hornegger , Siegfried Schneider
IPC分类号： A61B6/03
CPC分类号： A61B6/4441 , A61B6/02 , A61B6/4464 , A61B6/5235 , A61B6/584 , G01N23/046 , G01N2223/419 , Y10S378/901
摘要： In a method for generating a volume dataset of a subject with a first X-ray system having an X-ray source and an X-ray receiver and with a second X-ray system having an X-ray source and an X-ray receiver, the first X-ray system is rotated around an axis and sweeps a first angular range. Substantially simultaneously, a second series of 2D projections of the subject is acquired with the second X-ray system at projection angles differing from one another, by the second X-ray system being rotated around an axis and sweeping a second angular range differing from the first angular range. A volume dataset of the subject is generated from the first and second series of 2D projections of the subject acquired by the two X-ray systems.
摘要翻译：一种用于利用具有X射线源和X射线接收器的第一X射线系统以及具有X射线源和X射线接收器的第二X射线系统来生成被摄体的体数据集的方法，第一X射线系统围绕轴旋转并扫过第一角度范围。基本上同时地，以第二X射线系统以相互不同的投影角度获取对象的第二系列2D投影，第二X射线系统围绕轴线旋转并且扫掠与第二X射线系统不同的第二角度范围第一角度范围。由两个X射线系统获取的对象的第一和第二2D投影系列产生该对象的体数据集。

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