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21. 发明授权

US4394382A Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds 失效
标题翻译：二氢苯并吡喃化合物和包含所述化合物的药物组合物
公开(公告)号：US4394382A
公开(公告)日：1983-07-19
申请号：US271927
申请日：1981-06-09
申请人： Masami Shiratsuchi , Noboru Shimizu , Hiromichi Shigyo , Yoshinori Kyotani , Hisashi Kunieda , Kiyoshi Kawamura , Seiichi Sato , Toshihiro Akashi , Masahiko Nagakura , Naotoshi Sawada , Yasumi Uchida
发明人： Masami Shiratsuchi , Noboru Shimizu , Hiromichi Shigyo , Yoshinori Kyotani , Hisashi Kunieda , Kiyoshi Kawamura , Seiichi Sato , Toshihiro Akashi , Masahiko Nagakura , Naotoshi Sawada , Yasumi Uchida
IPC分类号： C07D311/04 , A61K31/353 , A61P9/02 , A61P9/04 , A61P21/02 , C07D311/22 , C07D311/58 , C07D311/64 , C07D311/66 , A61K31/35
CPC分类号： C07D311/22 , C07D311/58 , C07D311/64 , C07D311/66 , Y10S514/821
摘要： A benzopyran compound represented by the following ##STR1## wherein A represents a direct bond or the bond --CH.sub.2 --O--,R.sub.1 represents a member selected from the group consisting of a C.sub.3 -C.sub.5 alkyl group, a hydroxy-(C.sub.3 -C.sub.5 alkyl) group, a lower alkylamino-lower alkyl group, a nitrato-(C.sub.3 -C.sub.5 alkyl) group and a phenyl-(C.sub.1 -C.sub.5) alkyl group, provided that the phenyl may be substituted by a lower alkoxy group, R.sub.2 represents a member selected from the group consisting of hydrogen, halogen, OH, NO.sub.2, a carbamoyl group, a lower alkyl group, a lower alkoxy group, a lower alkyleneoxy group and acetyl group,R.sub.3 represents hydrogen or NO.sub.2,B represents a direct bond, a C.sub.1 -C.sub.7 alkylene group, a --O-lower alkylene group or a --CONH-lower alkylene group, andn represents 1 or 2;and an acid addition salt thereof and a pharmaceutical composition comprising aforesaid compound.
摘要翻译：由下式（I）表示的苯并吡喃化合物，其中A表示直接键或键-CH2-O-，R1表示选自C3-C5烷基，羟基 - （C3 -C 5烷基）基，低级烷基氨基 - 低级烷基，硝基 - （C 3 -C 5烷基）基和苯基 - （C 1 -C 5）烷基，条件是苯基可以被低级烷氧基取代，R 2 表示选自氢，卤素，OH，NO 2，氨基甲酰基，低级烷基，低级烷氧基，低级亚烷基氧基和乙酰基的成员，R 3表示氢或NO 2，B表示直接键，C 1 -C 7亚烷基，-O-低级亚烷基或-CONH-低级亚烷基，n表示1或2; 及其酸加成盐和包含上述化合物的药物组合物。

22. 发明申请

US20100120172A1 SUBSTANCE WITH ANTITHROMBOTIC ACTIVITY AND METHOD FOR DETECTING GLYCOKALLIDIN 审中-公开
标题翻译：具有抗血小板活性的物质和用于检测谷丙素的方法
公开(公告)号：US20100120172A1
公开(公告)日：2010-05-13
申请号：US12548898
申请日：2009-08-27
申请人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
发明人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
IPC分类号： G01N33/53
CPC分类号： C07K14/705 , C07K14/755 , C07K2317/52 , C07K2319/00 , C07K2319/30 , G01N33/86 , G01N2333/755
摘要： A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.
摘要翻译：一种方便检测血管性血友病因子与糖蛋白Ⅰb之间的结合的方法及其中使用的方法。固定在反应容器中的存在于布可菌素的反应器中的血管性血友病因子结合于通过将含有糖蛋白1b的血管性血友病变因子结合位点的部分蛋白的羧基末端与羧基末端相连的氨基末端免疫球蛋白分子的Fc区。然后检测上述免疫球蛋白分子的Fc区，从而检测血管性血友病因子与糖蛋白Ib之间的结合或抑制该结合。

23. 发明授权

US07608695B2 Substance with antithrombotic activity and method for detecting glycokallidin 失效
标题翻译：具有抗血栓活性的物质和检测糖蛋白的方法
公开(公告)号：US07608695B2
公开(公告)日：2009-10-27
申请号：US10825127
申请日：2004-04-16
申请人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
发明人： Naoyuki Fukuchi , Fumie Futaki , Morikazu Kito , Seiichi Sato , Takayuki Kajiura , Yukitsugu Ono , Koichi Ishii , Akiko Tanaka , Junko Shinozaki , Yasuko Jojima
IPC分类号： C12P21/08
CPC分类号： C07K14/705 , C07K14/755 , C07K2317/52 , C07K2319/00 , C07K2319/30 , G01N33/86 , G01N2333/755
摘要： A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.
摘要翻译：一种方便检测血管性血友病因子与糖蛋白Ⅰb之间的结合的方法及其中使用的方法。固定在反应容器中的存在于布可菌素的反应器中的血管性血友病因子结合于通过将含有糖蛋白1b的血管性血友病变因子结合位点的部分蛋白的羧基末端与羧基末端相连的氨基末端免疫球蛋白分子的Fc区。然后检测上述免疫球蛋白分子的Fc区，从而检测血管性血友病因子与糖蛋白Ib之间的结合或抑制该结合。

24. 发明申请

US20070259263A1 Battery Box Structure, Inter-Locking Structure of Electrical Equipment Box, and Electrical Equipment Box Structure 有权
标题翻译：电池盒结构，电气设备箱的锁定结构和电气设备箱体结构
公开(公告)号：US20070259263A1
公开(公告)日：2007-11-08
申请号：US11664699
申请日：2005-10-07
申请人： Kentaro Shibuya , Hiroshi Kosaka , Keishi Kousaka , Koichi Hasegawa , Seiichi Sato
发明人： Kentaro Shibuya , Hiroshi Kosaka , Keishi Kousaka , Koichi Hasegawa , Seiichi Sato
IPC分类号： H01M2/10
CPC分类号： H01M2/105
摘要： The battery box structure of the present invention includes: a plurality of battery modules; a pair of holding frames which hold the battery modules; and an insulator which is made from expanded insulating resin and which stores the holding frame.
摘要翻译：本发明的电池盒结构包括：多个电池模块; 一对保持电池模块的保持框架; 以及由膨胀绝缘树脂制成并且保存保持框架的绝缘体。

25. 发明授权

US07229320B2 Battery connection plate with voltage detection element 有权
标题翻译：带电压检测元件的电池连接板
公开(公告)号：US07229320B2
公开(公告)日：2007-06-12
申请号：US11353105
申请日：2006-02-14
申请人： Kazuaki Saito , Tomohiro Ikeda , Kentaro Shibuya , Hiroshi Kosaka , Seiichi Sato
发明人： Kazuaki Saito , Tomohiro Ikeda , Kentaro Shibuya , Hiroshi Kosaka , Seiichi Sato
IPC分类号： H01R33/00
CPC分类号： H01R11/281 , H01R11/26 , H01R13/665 , H01R27/00
摘要： A voltage detection terminal mounted to a housing plate body includes a bus bar connecting portion (4a) which is connected to a battery electrode and a bus bar (3) by bolt-nut connection, a detector connecting portion (4b) connected to voltage detector, and an interconnecting portion (4c) interconnecting the bus bar connecting portion and the detector connecting portion. A gap (c) for absorbing a length variation of a battery cell is formed between the plate body and the bus bar connecting portion, and the interconnecting portion (4c) includes a slanting portion (4c) for preventing the interconnecting portion from interference with the bus bar is formed at part of the interconnecting portion.
摘要翻译：安装到壳体主体的电压检测端子包括通过螺栓 - 螺母连接连接到电池电极和母线（3）的汇流条连接部分（4a），连接到电压检测器和互连部分（4c），其互连母线连接部分和检测器连接部分。用于吸收电池单元的长度变化的间隙（c）形成在板体和母线连接部分之间，并且互连部分（4c）包括用于防止互连部分受干扰的倾斜部分（4c）汇流条形成在互连部分的一部分。

26. 发明授权

US07211577B2 Water-soluble phenylpyridazine derivative and medicine containing the same 失效
标题翻译：水溶性苯基哒嗪衍生物及含有它的药物
公开(公告)号：US07211577B2
公开(公告)日：2007-05-01
申请号：US10544881
申请日：2004-03-16
申请人： Yoshinori Kyotani , Tomoyuki Koshi , Hiromichi Shigyo , Hideo Yoshizaki , Takahiro Kitamura , Shunji Takemura , Kyoko Yasuoka , Junko Totsuka , Seiichi Sato
发明人： Yoshinori Kyotani , Tomoyuki Koshi , Hiromichi Shigyo , Hideo Yoshizaki , Takahiro Kitamura , Shunji Takemura , Kyoko Yasuoka , Junko Totsuka , Seiichi Sato
IPC分类号： C07D237/04 , C07D403/06 , A61K31/50 , A61K31/51
CPC分类号： A61K31/501 , A61K31/50 , C07D237/14
摘要： A phenylpyridazine derivative represented by the formula (1): Wherein, R1, R2, R3, X, Y, Z and n have the same meaning as defined in the specification; or a salt thereof, or a medicine containing the compound. The present invention provides water-soluble phenylpyridazine derivatives and medicines containing them, which have excellent inhibitory activity against interleukin-β production, high water solubility and high oral absorbability.
摘要翻译：由式（1）表示的苯基哒嗪衍生物：其中R1，R2，R3，X，Y，Z和n与说明书中定义相同; 或其盐，或含有该化合物的药物。本发明提供水溶性苯基哒嗪衍生物和含有它们的药物，其对白细胞介素-β产生具有优异的抑制活性，高水溶性和高口服吸收性。

27. 发明授权

US07196101B2 Bis(5-aryl-2-pyridyl) derivatives 失效
标题翻译：双（5-芳基-2-吡啶基）衍生物
公开(公告)号：US07196101B2
公开(公告)日：2007-03-27
申请号：US10690671
申请日：2003-10-23
申请人： Hiroyuki Ishiwata , Seiichi Sato , Mototsugu Kabeya , Soichi Oda , Makoto Suda , Manabu Shibasaki
发明人： Hiroyuki Ishiwata , Seiichi Sato , Mototsugu Kabeya , Soichi Oda , Makoto Suda , Manabu Shibasaki
IPC分类号： A61P37/08 , A61K31/44 , C07D213/00
CPC分类号： C07D487/04 , C07D213/74 , C07D401/14 , C07D405/14 , C07D409/14
摘要： A bis(5-aryl-2-pyridyl) compound represented by formula (1) or a salt thereof: wherein A is a substituted or unsubstituted aromatic hydrocarbyl group or a substituted or unsubstituted aromatic heterocyclic group, and X is a group selected from the group consisting of moieties having formulas (2) to (5): wherein, in formula (2), m is an integer of 1 or 2; in formula (3), n is an integer of 1 to 6; and in formula (4), R is hydrogen or a lower alkyl group and p is an integer of 1 to 6.
摘要翻译：由式（1）表示的双（5-芳基-2-吡啶基）化合物或其盐：

28. 发明授权

US06890940B2 Bis(2-aryl-5-pyridyl) derivatives 失效
标题翻译：双（2-芳基-5-吡啶基）衍生物
公开(公告)号：US06890940B2
公开(公告)日：2005-05-10
申请号：US09893680
申请日：2001-06-29
申请人： Hiroyuki Ishiwata , Seiichi Sato , Mototsugu Kabeya , Soichi Oda , Makoto Suda , Manabu Shibasaki
发明人： Hiroyuki Ishiwata , Seiichi Sato , Mototsugu Kabeya , Soichi Oda , Makoto Suda , Manabu Shibasaki
IPC分类号： A61P37/00 , A61P37/08 , A61P43/00 , C07D213/74 , C07D401/14 , C07D405/14 , A61K31/44 , C07D213/00
CPC分类号： C07D213/74 , C07D401/14 , C07D405/14
摘要： A bis(2-aryl-5-pyridyl) compound having formula (1) or a salt thereof: wherein A is a substituted or unsubstituted aromatic hydrocarbon group, and X is a substituent having one of the following formulas (2) to (4): wherein, in formula (2), R1 is a hydrogen atom or a di(lower alkyl)amino(lower alkyl) group, and m is an integer of 1 or 2; in formula (3), Y1 and Y2 each is a nitrogen atom or a CH group, and n is 0 or an integer of 1 to 6; in formula (4), R2 and R3 each is a hydrogen atom or a lower alkyl group, Z represents a single bond, a substituted methylene group, a substituted imino group, an oxygen atom or a cycloalkylene group, and p and q each is 0 or an integer of 1 to 6.
摘要翻译：具有式（1）的双（2-芳基-5-吡啶基）化合物或其盐：其中A是取代或未取代的芳族烃基，X是具有下式（2）至（4）中的一个的取代基）其中，在式（2）中，R 1是氢原子或二（低级烷基）氨基（低级烷基）基团，m是1或2的整数; 在式（3）中，Y 1和Y 2各自为氮原子或CH基团，n为0或1至6的整数; 在式（4）中，R 2和R 3各自为氢原子或低级烷基，Z表示单键，取代亚甲基，取代亚氨基基团，氧原子或亚环烷基，p和q各自为0或1〜6的整数。

29. 发明授权

US06685777B2 Paste applicator and paste application method for die bonding 失效
标题翻译：贴片涂布机和贴剂应用方法
公开(公告)号：US06685777B2
公开(公告)日：2004-02-03
申请号：US09998526
申请日：2001-11-28
申请人： Seiichi Sato , Hitoshi Mukojima , Nobuyuki Iwashita , Nobuyuki Suefuji , Mitsuru Ozono
发明人： Seiichi Sato , Hitoshi Mukojima , Nobuyuki Iwashita , Nobuyuki Suefuji , Mitsuru Ozono
IPC分类号： B05C1100
CPC分类号： H01L24/27 , H01L21/67144 , H01L21/6715 , H01L21/67253 , H01L23/49513 , H01L24/29 , H01L24/31 , H01L24/743 , H01L24/83 , H01L2224/743 , H01L2224/83192 , H01L2224/83194 , H01L2224/8385 , H01L2924/01004 , H01L2924/01005 , H01L2924/01006 , H01L2924/01023 , H01L2924/01033 , H01L2924/01039 , H01L2924/01082 , H01L2924/07802 , H01L2924/00
摘要： A paste applicator and paste application method for die bonding apply paste to adhere a semiconductor chip on a substrate. Data on paste application volume and application pattern which can be identified from paste thickness and chip size are stored. A dispensing flow rate calculator calculates dispensing flow rate of a dispenser based on the paste application volume data and application pattern data when the paste is dispensed from the dispenser and pressure fed to an application nozzle for applying paste. Based on this calculated dispensing flow rate and application pattern data, a dispenser controller controls the dispenser and a transfer table controller controls the transfer table for moving the application nozzle.
摘要翻译：用于管芯接合的糊剂涂布器和糊剂施加方法施加糊剂以将半导体芯片粘附在基底上。存储可以从糊料厚度和芯片尺寸确定的粘贴应用体积和应用模式的数据。分配流量计算器基于糊料从分配器中分配出来的浆料施加量数据和应用模式数据来计算分配器的分配流量，并且将压力供给到用于施加浆料的施加喷嘴。基于该计算的分配流量和应用模式数据，分配器控制器控制分配器，并且转移表控制器控制用于移动施加喷嘴的转移台。

30. 发明授权

US06605315B1 Bonding paste applicator and method of using it 有权
标题翻译：粘合膏涂布器及其使用方法
公开(公告)号：US06605315B1
公开(公告)日：2003-08-12
申请号：US09704728
申请日：2000-11-03
申请人： Mitsuru Ozono , Seiichi Sato , Nobuyuki Suefuji , Nobuyuki Iwashita
发明人： Mitsuru Ozono , Seiichi Sato , Nobuyuki Suefuji , Nobuyuki Iwashita
IPC分类号： B05D510
CPC分类号： H01L24/27 , H01L24/29 , H01L24/743 , H01L24/83 , H01L2224/743 , H01L2224/83192 , H01L2224/83194 , H01L2224/8385 , H01L2924/01005 , H01L2924/01006 , H01L2924/01033 , H01L2924/01039 , H01L2924/01082 , H01L2924/07802 , Y10T29/4913
摘要： The object of the present invention is to provide a bonding paste applicator and a method of applying a bonding paste which allow satisfactory paste applying quality and excellent operability to be realized. A bonding paste application method for applying a bonding paste by making a drawing with a paste applying nozzle made to move to a position, where a chip is mounted on a substrate, comprises the steps of storing in advance in a storing unit 46 a drawing pattern for controlling each of X, Y and Z axes to move a paste applying nozzle and a drawing pattern setting table 53 to show a category corresponding to the size of a chip to be bonded, selecting a drawing pattern corresponding to the size of the chip, which has been designated, by means of a drawing pattern selecting unit 54 and obtaining a speed pattern for each of the X, Y and Z axes based on the selected drawing pattern by means of a speed pattern computing unit 55. Accordingly, it is no longer required to set up a drawing pattern every time occasion demands and a paste can be applied properly with excellent paste applying quality and satisfactory operability without fail.
摘要翻译：本发明的目的是提供一种粘合膏施加器和施加粘合膏的方法，其能够实现令人满意的糊料施加质量和优异的可操作性。一种用于通过利用制成移动到芯片安装在基板上的位置的糊状施加喷嘴进行拉伸来施加粘合膏的粘合膏施加方法包括以下步骤：将预先存储在存储单元46中的拉丝图案为了控制X，Y和Z轴中的每一个，移动糊剂施加喷嘴和绘图图形设置表53，以显示与要粘合的芯片的尺寸对应的类别，选择与芯片的尺寸对应的绘制图案，已经通过绘图模式选择单元54被指定，并且通过速度模式计算单元55基于所选择的绘图模式来获得X，Y和Z轴中的每一个的速度图案。因此，它不是需要更长时间才能在每次需要时设置绘图图案，并且可以适当地应用糊状物，并且不会出现具有优异的糊剂施加质量和令人满意的操作性。

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