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21. 发明授权

US09457142B2 Device and method for delivery of two or more drug agents 有权
标题翻译：用于递送两种或更多种药剂的装置和方法
公开(公告)号：US09457142B2
公开(公告)日：2016-10-04
申请号：US13509603
申请日：2010-11-29
申请人： Shane Alistair Day , Daniel Thomas De Sausmarez Lintell , Steven Wimpenny , Christopher Jones , Aidan Michael O'Hare , Barry Yates , Robert Veasey , Christopher James Smith , Malcolm Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall
发明人： Shane Alistair Day , Daniel Thomas De Sausmarez Lintell , Steven Wimpenny , Christopher Jones , Aidan Michael O'Hare , Barry Yates , Robert Veasey , Christopher James Smith , Malcolm Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall
IPC分类号： A61M37/00 , A61M5/142 , A61M5/172 , A61M5/19 , A61M5/20 , A61M5/315 , A61M5/24 , A61M5/31
CPC分类号： A61M5/19 , A61M5/14244 , A61M5/14248 , A61M5/1723 , A61M5/20 , A61M5/24 , A61M5/31511 , A61M5/31525 , A61M5/31546 , A61M5/31583 , A61M5/3202 , A61M5/3294 , A61M5/3295 , A61M5/347 , A61M2005/2407 , A61M2005/2411 , A61M2005/2496 , A61M2005/3126 , A61M2005/31518 , A61M2005/31588 , A61M2205/14 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/6063 , A61M2205/6072 , A61M2205/8206
摘要： A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.
摘要翻译：构造成递送至少一剂两种或更多种药物的计算机化机电药物递送装置。该装置包括控制单元。机电驱动单元可操作地联接到控制单元和用于第一药剂的主容器和用于流体试剂的第二储存器，例如液体。第二种药物。操作员界面与控制单元通信。单个分配组件被配置为与初级和次级容器流体连通。操作面板的激活设定来自主贮存器的第一剂量，并且基于第一剂量和治疗剂量分布，该控制单元构造成确定流体试剂的剂量或范围。或者，控制单元确定或计算第三药剂的剂量或范围。此外，公开了一种用于药物输送装置的分配界面。

22. 发明授权

US08911412B2 Interlock mechanism for a drug delivery device and drug delivery device 有权
标题翻译：用于药物递送装置和药物递送装置的联锁机制
公开(公告)号：US08911412B2
公开(公告)日：2014-12-16
申请号：US13139918
申请日：2009-12-17
申请人： Christopher James Smith
发明人： Christopher James Smith
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/31591 , A61M5/20
摘要： The invention refers to an interlock mechanism for restricting a rotational movement of a rotatable component (1) of a drug delivery device (10) and to a method for controlling the rotational movement of the rotatable component (1). The method comprises the steps of: translatively moving a trigger arm (6) engaged with a protrusion (7) of a latch arm (5) from an initial position for pivoting the latch arm (5) out of one of at least one catches (3) provided in a cam profile of the rotatable component (1) thus allowing the rotatable component (1), biased by an energy source, to rotate; pivoting the trigger arm (5) by one of at least one cams (4) provided in the cam profile during the rotation (R) of the rotatable component (1) whereby the trigger arm (6) is disengaged from the protrusion (7) thus allowing the latch arm (5) to re-engage with one of the catches (3) to stop the rotational movement (R) and whereby an interlock means (8) catches and holds the trigger arm (6) in its translatively moved and pivoted position until the interlock means (8) is released by a reset means; translatively moving the trigger arm (6) back into the initial position once the interlock means (8) is released thereby allowing it to pivot back and re-engage with the protrusion (7).
摘要翻译：本发明涉及一种用于限制药物输送装置（10）的可旋转部件（1）的旋转运动的互锁机构和用于控制可旋转部件（1）的旋转运动的方法。该方法包括以下步骤：将与闩锁臂（5）的突起（7）接合的触发臂（6）从初始位置平移移动，以将闩锁臂（5）从至少一个卡扣（ 3）设置在可旋转部件（1）的凸轮轮廓中，从而允许由能量源偏压的可旋转部件（1）旋转; 在可旋转部件（1）的旋转（R）期间，将触发臂（5）由设置在凸轮轮廓中的至少一个凸轮（4）中的一个枢转，由此触发臂（6）从突起（7）脱离，从而允许闩锁臂（5）与其中一个卡扣（3）重新接合以停止旋转运动（R），由此互锁装置（8）将扳机臂（6）卡住并保持在其平移运动枢转位置，直到互锁装置（8）被复位装置释放; 一旦互锁装置（8）被释放，就将扳机臂（6）平移地移动回到初始位置，从而使其能够枢转并与突起（7）重新接合。

23. 发明申请

US20140200518A1 INJECTION DEVICE 有权
标题翻译：注射装置
公开(公告)号：US20140200518A1
公开(公告)日：2014-07-17
申请号：US14240805
申请日：2012-09-11
申请人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
发明人： Matthew Ekman , Christopher James Smith , Troy Baker , Graham Wilson , Gareth Roberts , John Slemmen
IPC分类号： A61M5/32
CPC分类号： A61M5/3204 , A61M5/3202 , A61M5/326 , A61M2005/3263 , A61M2005/3267 , A61M2205/586
摘要： An injection device for administering a liquid is presented that comprises a pre-filled syringe and a safety mechanism for providing needle safety for an injection needle of the pre-filled syringe. The pre-filled syringe comprises a barrel containing the liquid and a stopper translatably disposed within the barrel, where the injection needle attached to a distal end of the barrel. The safety mechanism comprises a substantially cylindrical housing adapted to contain the pre-filled syringe, a plunger connectable to the stopper of the pre-filled syringe and adapted to be translated in a distal direction (D) to expel the liquid through the injection needle, an energizable biasing means arranged between the housing and the pre-filled syringe, wherein the energized biasing means is capable of biasing the pre-filled syringe with respect to the housing in a proximal direction (P) and a retaining mechanism for retaining the pre-filled syringe with respect to the housing in a first retracted position (R1), in an advanced position (A) and in a second retracted position (R2).
摘要翻译：提供了一种用于施用液体的注射装置，其包括预填充注射器和用于为预填充注射器的注射针提供针头安全性的安全机构。预装注射器包括容纳液体的桶和可移动地设置在筒体内的塞子，其中注射针附接到筒的远端。安全机构包括适于容纳预填充的注射器的基本上圆柱形的壳体，可连接到预填充注射器的止动件的柱塞，并适于沿远端方向（D）平移以通过注射针排出液体，可动的偏置装置，布置在壳体和预填充的注射器之间，其中通电的偏压装置能够在近端方向（P）和偏心预紧装置的相对于壳体的位置上偏置预填充的注射器，（R1），处于前进位置（A）和第二缩回位置（R2）中的相对于壳体的填充注射器。

24. 发明申请

US20130338612A1 APPARATUS FOR INTRAOCULAR INJECTION 审中-公开
标题翻译：眼内注射装置
公开(公告)号：US20130338612A1
公开(公告)日：2013-12-19
申请号：US14002181
申请日：2012-03-09
申请人： Christopher James Smith , David Heighton , Alastair Robert Clarke
发明人： Christopher James Smith , David Heighton , Alastair Robert Clarke
IPC分类号： A61F9/00
CPC分类号： A61F9/0017
摘要： An apparatus for intraocular injection comprising a body adapted to accommodate an injection device and a displacement device coupled to a distal portion of the body. The displacement device comprises a first portion and a second portion connected to the first portion. Axial movement of the first portion within the body in a distal direction causes the second portion to displace a superficial layer of an eye relative to an underlying layer of the eye.
摘要翻译：一种用于眼内注射的装置，包括适于容纳注射装置的主体和联接到主体的远端部分的移位装置。位移装置包括连接到第一部分的第一部分和第二部分。第一部分在主体内的远端方向的轴向运动使得第二部分相对于眼睛的下层移位眼睛的表层。

25. 发明申请

US20130306072A1 BLOWER AND PAP SYSTEM 审中-公开
标题翻译：鼓风和PAP系统
公开(公告)号：US20130306072A1
公开(公告)日：2013-11-21
申请号：US13983712
申请日：2012-02-22
申请人： Michael Bruce Moir , Roman Vinokur , Frederick Arlet May , Dmitri Anatolievich Doudkine , Barton John Kenyon , Christopher James Smith
发明人： Michael Bruce Moir , Roman Vinokur , Frederick Arlet May , Dmitri Anatolievich Doudkine , Barton John Kenyon , Christopher James Smith
IPC分类号： A61M16/00 , F04D17/08
CPC分类号： A61M16/0066 , A61M16/0666 , A61M16/0683 , A61M16/107 , A61M16/125 , A61M2202/0208 , A61M2205/3358 , A61M2205/42 , F04D17/08 , F04D17/16 , F04D29/048
摘要： A blower includes a housing including an inlet and an outlet, a stationary component provided to the housing, an impeller positioned between the inlet of the housing and the stationary component, and a motor adapted to drive the impeller. The stationary component includes a tube portion structured to retain and align a pair of bearings that rotatably support a rotor to which the impeller is coupled. The tube portion includes a diameter in a side closest to the impeller that is sufficient size to accommodate adhesive to retain one of the bearings.
摘要翻译：鼓风机包括壳体，其包括入口和出口，设置到壳体的固定部件，位于壳体的入口与固定部件之间的叶轮和适于驱动叶轮的马达。固定部件包括管部分，其被构造成保持和对准一对可旋转地支撑叶轮联接的转子的轴承。管部分包括最靠近叶轮的一侧的直径，其尺寸足够容纳粘合剂以保持其中一个轴承。

26. 发明申请

US20130211331A1 DRIVE ASSEMBLY, DRIVE COMPONENT AND DRUG DELIVERY DEVICE 有权
标题翻译：驱动组件，驱动组件和药物传送装置
公开(公告)号：US20130211331A1
公开(公告)日：2013-08-15
申请号：US13701995
申请日：2011-06-09
申请人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
发明人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
IPC分类号： F16H19/02 , A61M5/142
CPC分类号： A61M5/31551 , A61M5/142 , A61M5/31536 , A61M5/31555 , A61M5/31585 , A61M2205/581 , A61M2205/582 , F16H19/02 , Y10T74/18568
摘要： A drive assembly for a drug delivery device comprises a rotation member being configured to be rotated in a first direction during setting of a dose of a drug and to be rotated in a second direction during delivery of the dose, a drive component being configured to follow rotational movement of the rotation member in the second direction during delivery of the dose and a stop member being configured to prevent rotational movement of the drive component in the first direction. The drive component comprises a first drive part and a second drive part, coupled to each other such that relative rotational movement of the first and second drive parts is prevented and relative axial movement is permitted.
摘要翻译：用于药物递送装置的驱动组件包括旋转构件，其构造成在药物剂量的设定期间沿第一方向旋转并且在剂量递送期间沿第二方向旋转，驱动部件被配置为跟随在剂量输送期间旋转构件在第二方向上的旋转运动，以及止动构件被构造成防止驱动构件在第一方向上的旋转运动。驱动部件包括彼此连接的第一驱动部分和第二驱动部分，从而防止第一和第二驱动部件的相对旋转运动并允许相对的轴向移动。

27. 发明申请

US20130184652A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 有权
标题翻译：用于药物递送装置和药物递送装置的驱动机构
公开(公告)号：US20130184652A1
公开(公告)日：2013-07-18
申请号：US13702812
申请日：2011-06-09
申请人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
发明人： Christopher James Smith , Stephen David Butler , Mark Philip Horlock
IPC分类号： A61M5/315
CPC分类号： A61M5/31528 , A61M5/31543 , A61M5/31555 , A61M5/31585
摘要： A drive member and a rotation member are rotatable with respect to a housing. A stop member is rotationally locked with the housing. Clutches unidirectionally rotationally engage the drive member with the rotation member and with the stop member when a unit is attached to the housing. A separating member is disposed between the rotation member and the stop member. The separating member causes a separation of the rotation member, the drive member and the stop member when the unit is removed. A coupling feature of the separating member is provided to engage the unit and to move the separating member when the unit is being attached to the housing or is being removed.
摘要翻译：驱动构件和旋转构件可相对于壳体旋转。止动构件与壳体旋转地锁定。当单元附接到壳体时，离合器单向地旋转地与驱动构件旋转地接合旋转构件和止动构件。分离构件设置在旋转构件和止动构件之间。当单元被移除时，分离构件导致旋转构件，驱动构件和止动构件的分离。提供分离构件的联接特征以接合单元并且当单元附接到壳体或正在移除时移动分离构件。

28. 发明申请

US20130096513A1 AUTOMATIC INJECTION DEVICE WITH TORSIONAL SPRING 有权
标题翻译：具有扭转弹簧的自动注射装置
公开(公告)号：US20130096513A1
公开(公告)日：2013-04-18
申请号：US13579081
申请日：2011-02-15
申请人： Christopher James Smith
发明人： Christopher James Smith
IPC分类号： A61M5/315
CPC分类号： A61M5/3155 , A61M5/20 , A61M5/31543 , A61M5/31553 , A61M5/3156 , A61M5/31583 , A61M5/31593 , A61M2005/202
摘要： A semi-automatic “fixed” dose injection device is disclosed containing a reservoir of medicament, where a trigger controls the unwinding of a torsional spring to cause a predetermined injection of medicament from the reservoir through a disposable needle.
摘要翻译：公开了一种半自动“固定”剂量注射装置，其包含药剂储存器，其中触发器控制扭转弹簧的展开，以通过一次性针头从储存器预先注射药物。

29. 发明申请

US20120130316A1 Drug Delivery Device 有权
标题翻译：药物输送装置
公开(公告)号：US20120130316A1
公开(公告)日：2012-05-24
申请号：US13202249
申请日：2010-03-04
申请人： Malcolm Stanley Boyd , Robert Frederick Veasey , David Aubrey Plumptre , Stephen Minshull , Christopher James Smith , Patrick Gerard Linnane
发明人： Malcolm Stanley Boyd , Robert Frederick Veasey , David Aubrey Plumptre , Stephen Minshull , Christopher James Smith , Patrick Gerard Linnane
IPC分类号： A61M5/31
CPC分类号： A61M5/24 , A61M5/31525 , A61M2205/583 , A61M2205/584
摘要： The present invention relates to a drug delivery comprising a housing (10) adapted to retain a cartridge (16) and a piston rod (26), the piston rod (26) being adapted to drive a piston (28) so as to engage the piston (28) into the cartridge (16) in response to operating an operating button (30), and an indicator means (40) being capable of revealing usage related information of the drug delivery device (5), the indicator means (40) being movable with respect to the housing (10). Furthermore, using indicator means (40) on a drug delivery device (5), wherein the so as to reveal usage related information of the drug delivery device (5), wherein the indicator means (40) being movable with respect to a housing (10) of the drug delivery device (5) is disclosed.
摘要翻译：本发明涉及一种药物输送，其包括适于保持药筒（16）和活塞杆（26）的壳体（10），所述活塞杆（26）适于驱动活塞（28）以接合响应于操作操作按钮（30）而将活塞（28）插入到盒（16）中，以及指示装置（40）能够揭示药物输送装置（5）的使用相关信息，指示装置（40）可相对于壳体（10）移动。此外，在药物输送装置（5）上使用指示装置（40），其中，以便揭示药物输送装置（5）的使用相关信息，其中指示装置（40）可相对于壳体（ 10）的药物输送装置（5）。

30. 发明申请

US20120046643A1 INJECTION DEVICE 有权
标题翻译：注射装置
公开(公告)号：US20120046643A1
公开(公告)日：2012-02-23
申请号：US13140131
申请日：2009-12-18
申请人： David Plumptre , Christopher James Smith
发明人： David Plumptre , Christopher James Smith
IPC分类号： A61M5/31
CPC分类号： A61M5/31585 , A61M5/31541 , A61M5/31551 , A61M5/31558 , A61M5/3156 , A61M2005/3152 , A61M2205/581 , A61M2205/582
摘要： An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose setting direction (s) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction opposite to the dose setting direction (s).
摘要翻译：提供了一种用于施用固定剂量的药物的注射装置（1）。注射装置（1）包括壳体（2），其中包括驱动构件（3）的驱动机构至少部分地封闭，并且相对于驱动构件（3）固定的计量元件（34）。这里，可以通过以剂量设定方向相对于壳体（2）旋转计量元件（34）来设定剂量，并且可以通过朝向壳体（2）推动剂量元件（34）来分配剂量，。此外，提供了一种用于操作用于施用固定剂量的药物的注射装置（1）的方法：剂量可以通过旋转剂量元件（34）来设定，剂量可以通过推动剂量元件（ 34）朝向壳体（2），并且可以通过沿与剂量设定方向相反的方向旋转定量配料元件（34）来消除剂量。

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