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21. 发明授权

US5556789A Device for the simultaneous determination of several analytes 失效
标题翻译：用于同时测定几种分析物的装置
公开(公告)号：US5556789A
公开(公告)日：1996-09-17
申请号：US270162
申请日：1994-07-01
申请人： Ada Goerlach-Graw , Reinhard Baer , Rolf Lerch
发明人： Ada Goerlach-Graw , Reinhard Baer , Rolf Lerch
IPC分类号： G01N31/22 , B01L3/00 , G01N33/52 , G01N33/543 , G01N37/00 , G01N33/00
CPC分类号： B01L3/5023 , B01L2300/0816 , B01L2300/0864 , B01L2400/0406 , B01L2400/084 , Y10S436/807 , Y10S436/901
摘要： Device for the determination of analytes having a sample application point, several separate sample withdrawal zones that are each connected with the sample application point by one capillary transport path and that have several test elements for the individual determination of analytes wherein a retardation zone is provided on at least one of the transport paths. Material for the capillary transport of a liquid sample defines a sample application zone and a plurality of sample withdrawal zones connected to said application zone by a like plurality of transport paths. At least one of said paths has a retardation zone which assures that liquid applied to said application zone arrives simultaneously at said withdrawal zones, regardless of the lengths of the paths.
摘要翻译：用于测定具有样品应用点的分析物的装置，几个单独的取样区，其各自的样品取出区各自通过一个毛细管输送路径与样品施加点连接，并且具有用于单独测定分析物的几个测试元件，其中延迟区设置在至少一个传输路径。用于液体样品的毛细管输送的材料限定样品施加区域和通过相同的多个输送路径连接到所述施加区域的多个取样区域。所述路径中的至少一个具有延迟区域，其确保施加到所述应用区域的液体同时到达所述撤回区域，而不管路径的长度。

22. 发明授权

US5177022A Immune reactive porous carrier material 失效
标题翻译：免疫反应性多孔载体材料
公开(公告)号：US5177022A
公开(公告)日：1993-01-05
申请号：US236458
申请日：1988-08-25
申请人： Dieter Mangold , Siegfried Noetzel , Rolf Lerch , Jelmut Jering
发明人： Dieter Mangold , Siegfried Noetzel , Rolf Lerch , Jelmut Jering
IPC分类号： A61K39/00 , C07K16/00 , C07K17/12 , G01N33/543 , G01N33/78
CPC分类号： G01N33/54393 , G01N33/54386 , G01N33/78
摘要： The present invention provides an immune reactive porous carrier material comprising a porous carrier material with immune complexes precipitated thereon, wherein the porous carrier material is treated with at least one wet-strength agent.The present invention also provides processes for the production of this immune reactive porous carrier material.
摘要翻译：本发明提供一种免疫反应性多孔载体材料，其包含其上沉淀有免疫复合物的多孔载体材料，其中所述多孔载体材料用至少一种湿强度剂处理。本发明还提供了生产这种免疫反应性多孔载体材料的方法。

23. 发明授权

US5160486A Test carrier utilizing reaction of two bioaffine binding partners 失效
标题翻译：使用两个生物伙伴合作伙伴的测试携带者反应
公开(公告)号：US5160486A
公开(公告)日：1992-11-03
申请号：US450557
申请日：1989-12-14
申请人： Reiner Schlipfenbacher , Dieter Mangold , Rolf Lerch , Joachim Steinbiss
发明人： Reiner Schlipfenbacher , Dieter Mangold , Rolf Lerch , Joachim Steinbiss
IPC分类号： G01N33/543 , G01N33/558
CPC分类号： G01N33/54386 , G01N33/558 , Y10S435/805
摘要： Test carrier for analysis of a sample liquid with the help of a specific binding reaction of two bioaffine binding partners, one of which is contained in the sample and one in the reagent system of the test carrier, with several capillary-active test zones (11-16; 21-25) arranged substantially next to one another on a base layer (2). The test zones are in liquid contact with one another so that they form a liquid transport path (20, 30) along which a liquid flows, driven by capillary forces, from a start zone (11, 21), a reaction thereby taking place between the first binding partner and the reagent system containing the second reaction partner, which reaction leads to a labelled species characteristic for the desired analysis. A third binding partner specific for the first binding partner sets as capturing reagent which is so arranged in a zone of the liquid transport path (20, 30) and is so measured with regard to the amount used that it binds a part of the first binding partner and thereby removes it from the reaction leading to the characteristic labelled species. A process for the analysis of a liquid sample with the above test carrier is also provided.
摘要翻译：借助于两个生物亚硫酸结合配偶体的特异性结合反应（其中一个包含在样品中，一个在测试载体的试剂系统中）与样品液体分离的测试载体，具有几个毛细管活性测试区（11 -16; 21-25），其基本上彼此相邻布置在基底层（2）上。测试区彼此液体接触，使得它们形成液体输送路径（20,30），液体沿着该液体输送路径（20,30）从毛细作用力从起始区域（11,21）流动，由此发生反应第一结合配偶体和含有第二反应伴侣的试剂系统，该反应导致所需分析的标记物质特征。特定于第一结合伴侣的第三结合配偶体设置为捕获试剂，其被布置在液体输送路径（20,30）的区域中，并且相对于所使用的量如此测量，其结合了第一结合物的一部分从而将其从导致特征标记物种的反应中除去。还提供了使用上述测试载体分析液体样品的方法。

24. 发明授权

US4964586A Releasable holding device for cores 失效
标题翻译：用于芯的可释放保持装置
公开(公告)号：US4964586A
公开(公告)日：1990-10-23
申请号：US431160
申请日：1989-11-03
申请人： Rolf Lerch
发明人： Rolf Lerch
IPC分类号： B65H16/06 , B65H18/04 , B65H75/24
CPC分类号： B65H75/246 , Y10T279/1074 , Y10T279/1079
摘要： A device for releasably holding a core or the like relative to a drive shaft passing therethrough includes at least two clamping elements located within the core. Guide pieces are fixed to a ring disc which surrounds a ring connected to the drive shaft. These guide pieces allow the clamping elements to move radially relative to the drive shaft and hold the core. A friction brake is provided to brake the ring relative to the ring disc. Also, a locking pawl arrangement is provided to selectively prevent the ring disc from rotating with the drive shaft. Accordingly, back slipping is prevented which undesirably loosens the core from the clamping elements.
摘要翻译：用于可释放地保持芯等相对于穿过其的驱动轴的装置包括位于芯内的至少两个夹紧元件。引导件固定在围绕与驱动轴连接的环的环形盘上。这些引导件允许夹紧元件相对于驱动轴径向移动并保持芯部。提供摩擦制动器以相对于环形盘制动环。而且，提供锁定爪装置以选择性地防止环形盘与驱动轴一起旋转。因此，防止后滑动，这不利地使芯从夹紧元件松动。

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