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21. 发明授权

US07771415B2 Method for safely and efficiently navigating magnetic devices in the body 有权
公开(公告)号：US07771415B2
公开(公告)日：2010-08-10
申请号：US11603339
申请日：2006-11-21
申请人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
发明人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
IPC分类号： A61B17/00
CPC分类号： A61B1/00158 , A61B1/01 , A61B17/12022 , A61B17/12113 , A61B17/12131 , A61B34/70 , A61B34/73 , A61B2017/00876 , A61B2017/1205 , A61B2034/733 , A61M25/0105 , A61M25/0127
摘要： A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.

22. 发明授权

US07341063B2 Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments 失效
标题翻译：具有可变磁矩的磁性医疗设备和导航具有可变磁矩的磁性医疗设备的方法
公开(公告)号：US07341063B2
公开(公告)日：2008-03-11
申请号：US11389547
申请日：2006-03-24
申请人： Jeffrey M. Garbibaldi , Roger N. Hastings
发明人： Jeffrey M. Garbibaldi , Roger N. Hastings
IPC分类号： A61B19/00
CPC分类号： A61B17/3421 , A61B1/00158 , A61B34/73 , A61B90/36 , A61B2018/00023 , A61M25/0127
摘要： A method of navigating a medical device having a changeable magnetic moment within an operating region within a patient, the method includes applying a navigating magnetic field to the operating region with an external source magnet, and changing the direction of the magnetic moment in the medical device to change the orientation of the medical device in a selected direction within the operating region. The magnet moment of the medical device can be created by one or more electromagnet coils, in which case the magnetic moment can be changed by changing the current to the coil. Alternatively, the magnetic moment of the medical device can be created by one or more permanent magnets, in which case the magnetic moment can be changed by mechanically or magnetically manipulating the permanent magnet.
摘要翻译：一种在患者体内的操作区域内导航具有可变磁矩的医疗装置的方法，所述方法包括：利用外部源磁体对操作区域施加导航磁场，以及改变医疗装置中的磁矩方向以在操作区域内沿所选择的方向改变医疗装置的方向。医疗装置的磁矩可以由一个或多个电磁线圈产生，在这种情况下，可以通过改变线圈的电流来改变磁矩。或者，医疗装置的磁矩可以由一个或多个永磁体产生，在这种情况下，可以通过机械或磁力操纵永久磁铁来改变磁矩。

23. 发明授权

US07264584B2 Method for safely and efficiently navigating magnetic devices in the body 有权
标题翻译：安全有效地导航身体中磁性装置的方法
公开(公告)号：US07264584B2
公开(公告)日：2007-09-04
申请号：US10796568
申请日：2004-03-09
申请人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
发明人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
IPC分类号： A61N5/00 , C01S19/00 , A61F2/28
CPC分类号： A61B1/00158 , A61B1/01 , A61B17/12022 , A61B17/12113 , A61B17/12131 , A61B34/70 , A61B34/73 , A61B2017/00876 , A61B2017/1205 , A61B2034/733 , A61M25/0105 , A61M25/0127
摘要： A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.
摘要翻译：一种通过至少一个外部源的移动来将具有与其远端相关联的具有磁响应元件的医疗装置转动到患者身体内部的操作区域内的操作区域的方法，所述操作区域从初始方向到期望的最终方向磁铁。至少一个外部源磁体以使得磁性医疗装置的远端的方向从初始方向改变到期望的最终方向的方式移动，而不会从包含初始方向的平面和期望的最终方向显着偏离方向。

24. 发明授权

US07248914B2 Method of navigating medical devices in the presence of radiopaque material 有权
标题翻译：在不透射线材料存在下导航医疗器械的方法
公开(公告)号：US07248914B2
公开(公告)日：2007-07-24
申请号：US10186264
申请日：2002-06-28
申请人： Roger N. Hastings , Steven J. Ferry , Demetrius K. Lopes
发明人： Roger N. Hastings , Steven J. Ferry , Demetrius K. Lopes
IPC分类号： A61B5/05
CPC分类号： A61B5/06 , A61B5/062 , A61B6/12
摘要： A method of navigating the distal end of a medical device through an operating region in a subject's body includes displaying an x-ray image of the operating region, including the distal end of the medical device; determining the location of the distal end of the medical device in a reference frame translatable to the displayed x-ray image; and displaying an enhanced indication of the distal end of the medical device on the x-ray image to facilitate the navigation of the distal end of the device in the operating region.
摘要翻译：通过主体的操作区域导航医疗装置的远端的方法包括显示包括医疗装置的远端的操作区域的X射线图像; 确定所述医疗装置的远端在参考框架中的位置，所述参考框架可转换成所显示的X射线图像; 以及在x射线图像上显示医疗装置的远端的增强指示，以便于在操作区域中设备的远端的导航。

25. 发明授权

US07008418B2 Magnetically assisted pulmonary vein isolation 失效
标题翻译：磁辅助肺静脉隔离
公开(公告)号：US07008418B2
公开(公告)日：2006-03-07
申请号：US10435713
申请日：2003-05-09
申请人： Andrew F. Hall , Roger N. Hastings
发明人： Andrew F. Hall , Roger N. Hastings
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B34/73 , A61B2018/00214 , A61B2018/00273 , A61B2018/00375 , A61B2018/00898
摘要： A method for forming an ablation pattern to electrically isolate a vessel having an ostium from a chamber formed within a patient for treatment of cardiac arrhythmia. The distal portion of a catheter is navigated to a chamber. An anchor member is deployed from the distal end of the catheter into the chamber, and the distal end is navigated into the ostium of the vessel, and temporarily secured in the vessel. An ablation member is deployed from the distal end of the catheter into the chamber and successively navigated into contact with tissue adjacent the ostium and ablating the tissue in contact with the ablation member to form a line of ablation. At least one of the navigating the distal portion of the catheter, navigating the anchor member and navigating the ablation member is performed by applying an external magnetic field to orient the device being navigated.
摘要翻译：一种用于形成消融图案以将具有口腔的血管与形成在患者体内的腔室电隔离以治疗心律失常的方法。导管的远端部分导航到腔室。锚定构件从导管的远端部署到腔室中，并且远端导航到血管的口中，并临时固定在血管中。将消融部件从导管的远端部署到腔室中并且相继地导航到邻近口部的组织接触并且消融与消融部件接触的组织以形成消融线。通过施加外部磁场来定向正在导航的装置来执行导航导管的远端部分，导航锚定构件和导航消融部件中的至少一个。

26. 发明授权

US06817364B2 Magnetically navigated pacing leads, and methods for delivering medical devices 失效
标题翻译：磁导航起搏线，以及提供医疗器械的方法
公开(公告)号：US06817364B2
公开(公告)日：2004-11-16
申请号：US09911351
申请日：2001-07-23
申请人： Jeffrey M. Garibaldi , Jonathan C. Sell , Roger N. Hastings , Andrew F. Hall
发明人： Jeffrey M. Garibaldi , Jonathan C. Sell , Roger N. Hastings , Andrew F. Hall
IPC分类号： A61N105
CPC分类号： A61N1/056 , A61M25/0127 , A61N2001/0578
摘要： A method of placing a pacing lead in the heart includes introducing a distal end of a delivery catheter into the patient's vasculature; magnetically navigating the distal end of the delivery catheter to the patient's heart; deploying a pacing lead from the distal end of the delivery catheter; and magnetically navigating the pacing lead to the pacing application site.
摘要翻译：将起搏引线放置在心脏中的方法包括将输送导管的远端引入患者的脉管系统中; 将输送导管的远端磁导向患者的心脏; 从输送导管的远端展开起搏引线; 并将起搏导联磁力导航到起搏应用场所。

27. 发明授权

US06702804B1 Method for safely and efficiently navigating magnetic devices in the body 有权
公开(公告)号：US06702804B1
公开(公告)日：2004-03-09
申请号：US09678640
申请日：2000-10-03
申请人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
发明人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
IPC分类号： A61B1700
CPC分类号： A61B1/00158 , A61B1/01 , A61B17/12022 , A61B17/12113 , A61B17/12131 , A61B34/70 , A61B34/73 , A61B2017/00876 , A61B2017/1205 , A61B2034/733 , A61M25/0105 , A61M25/0127
摘要： A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.

28. 发明授权

US06375606B1 Methods of and apparatus for treating vascular defects 失效
标题翻译：治疗血管缺陷的方法和装置
公开(公告)号：US06375606B1
公开(公告)日：2002-04-23
申请号：US09430118
申请日：1999-10-29
申请人： Jeffrey M. Garibaldi , Bevil J. Hogg , Roger N. Hastings , Brooke Ren
发明人： Jeffrey M. Garibaldi , Bevil J. Hogg , Roger N. Hastings , Brooke Ren
IPC分类号： A61M3700
CPC分类号： A61N2/02 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12186 , A61B2017/00876 , A61B2017/12086 , A61L24/001 , A61L24/02 , A61L24/046 , A61L24/06 , A61L24/08 , A61L24/106 , A61L24/108 , A61L31/022 , A61L31/18 , A61L2430/36 , C08L35/04 , C08L1/12
摘要： A method of and apparatus for treating vascular defects. A catheter having a selectively energizeable coil on its distal end. The catheter is particularly adapted for the delivery of magnetic embolic materials. The coil can be energized to aid in the magnetic navigation of the catheter, to help retain magnetic material in the catheter, to draw ejected magnetic material back into the catheter. A catheter can also be used to deliver a magnetic patch that can be magnetically applied to a vascular defect such as an aneurysm.
摘要翻译：一种治疗血管缺陷的方法和装置。导管在其远端具有可选择性地通电的线圈。导管特别适用于输送磁性栓塞材料。线圈可以通电以帮助导管的磁导航，以帮助将磁性材料保留在导管中，以将排出的磁性材料抽回到导管中。还可以使用导管来递送可以磁力施加到诸如动脉瘤的血管缺陷的磁性贴片。

29. 发明授权

US06330467B1 Efficient magnet system for magnetically-assisted surgery 失效
标题翻译：用于磁辅助手术的高效磁铁系统
公开(公告)号：US06330467B1
公开(公告)日：2001-12-11
申请号：US09287397
申请日：1999-04-06
申请人： Francis M. Creighton, IV , Andrew F. Hall , Roger N. Hastings , Rogers C. Ritter
发明人： Francis M. Creighton, IV , Andrew F. Hall , Roger N. Hastings , Rogers C. Ritter
IPC分类号： A61B505
CPC分类号： A61B34/73 , A61B1/00158 , A61B34/70 , A61B90/36 , A61B2034/301 , A61B2034/733 , A61B2034/742 , A61M25/0127
摘要： A system for magnetically assisted surgery includes a magnetic support structure, a patient support structure and a magnet having at least four poles attached to the magnetic support structure so that the magnet provides a near-field magnetic field in an operating region of a patient supported by the patient support structure. The magnet is moveable so that the direction of the magnetic field lines in the operating region is adjustable. The magnet may include a pair of essentially semicircular half-segments permanently magnetized and joined in an extremely stable disk configuration. The magnetic field and gradient field provided by the magnet is such that movement of the disk in one plane combined with rotation of the disk is sufficient to orient the magnetic field during surgical use, thereby reducing interference to medical imaging devices needed during surgery. An example of a medical delivery device that may be used for surgery in conjunction with this system is a flexible endoscope or catheter having a series of magnetically permeable rings.
摘要翻译：一种用于磁辅助手术的系统包括磁性支撑结构，患者支撑结构和具有至少四个磁极附接到磁性支撑结构的磁体，使得磁体在患者的操作区域中提供近场磁场，患者支撑结构。磁体是可移动的，使得操作区域中的磁场线的方向是可调节的。磁体可以包括一对基本上半圆形的半段，其永久地磁化并以非常稳定的磁盘配置连接。由磁体提供的磁场和梯度场使得在一个平面中与盘的旋转相结合的盘的移动足以在手术使用期间定向磁场，从而减少对手术期间所需的医学成像装置的干扰。结合该系统可用于手术的医疗输送装置的实例是具有一系列导磁环的柔性内窥镜或导管。

30. 发明授权

US06296604B1 Methods of and compositions for treating vascular defects 失效
标题翻译：治疗血管缺陷的方法和组合物
公开(公告)号：US06296604B1
公开(公告)日：2001-10-02
申请号：US09430200
申请日：1999-10-29
申请人： Jeffrey M. Garibaldi , Bevil J. Hogg , Roger N. Hastings , Brooke Ren
发明人： Jeffrey M. Garibaldi , Bevil J. Hogg , Roger N. Hastings , Brooke Ren
IPC分类号： A61M3700
CPC分类号： A61N2/02 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12186 , A61B2017/00876 , A61B2017/12086 , A61L24/001 , A61L24/02 , A61L24/046 , A61L24/06 , A61L24/08 , A61L24/106 , A61L24/108 , A61L31/022 , A61L31/18 , A61L2430/36 , C08L35/04 , C08L1/12
摘要： A magnetic embolic agent for magnetic placement in a vascular defect includes a bicompatible polymer, a solvent, an adhesive, and magnetic particles.
摘要翻译：用于磁性放置在血管缺损中的磁性栓塞剂包括双相容聚合物，溶剂，粘合剂和磁性颗粒。

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