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21. 发明申请

US20120197120A1 METHODS FOR TREATMENT OF SWEAT GLANDS 有权
标题翻译：施肥方法
公开(公告)号：US20120197120A1
公开(公告)日：2012-08-02
申请号：US13444485
申请日：2012-04-11
申请人： Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
发明人： Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61M37/00 , A61B8/00
CPC分类号： A61N7/02 , A61B8/4281 , A61B17/320068 , A61B2018/00005 , A61N7/00 , A61N2007/0004 , A61N2007/0052 , A61N2007/0078
摘要： A method and system for ultrasound treatment of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
摘要翻译：提供了一种用于汗腺超声处理的方法和系统。用于针对性治疗汗腺的示例性方法和系统可以以各种方式配置，例如仅通过使用治疗，治疗和监测，成像和治疗，或治疗，成像和监测，和/或通过使用聚焦，通过控制各种空间和时间参数，不聚焦或散焦超声波。因此，可以在异常汗腺群体位于皮肤表面下方的特定深度沉积烧蚀能量。

22. 发明申请

US20120143056A1 Methods and systems for treating plantar fascia 审中-公开
标题翻译：治疗足底筋膜的方法和系统
公开(公告)号：US20120143056A1
公开(公告)日：2012-06-07
申请号：US13136541
申请日：2011-08-02
申请人： Michael H. Slayton , Peter G. Barthe
发明人： Michael H. Slayton , Peter G. Barthe
IPC分类号： A61B8/00 , A61N7/00
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B17/320068 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments, described herein, provide methods and systems for the treatment of plantar fascia. In some embodiments, a method of non-invasive treatment of plantar fasciacan include the steps of identifying a damage location comprising a planter fascia; directing a conformal distribution of ultrasound energy to the plantar fascia at the damage location; creating a plurality of micro lesions in the plantar fascia at the damage location; initiating healing of a plurality of micro tears in the plantar fascia at the damage location; and sparing intervening tissue between the plantar fascia and a surface of a sole of a foot.
摘要翻译：本文所述的各种实施例提供了用于治疗足底筋膜的方法和系统。在一些实施方案中，一种非侵入性治疗足底跖皮的方法包括鉴定包括花坛筋膜的损伤位置的步骤; 将损伤位置处的超声能量的适形分布引导到足底筋膜; 在损伤位置的足底筋膜中产生多个微小损伤; 在损伤位置引发足底筋膜中的多个微小眼泪的愈合; 并且在足底筋膜和足底的表面之间节省介入组织。

23. 发明授权

US07824348B2 System and method for variable depth ultrasound treatment 有权
标题翻译：可变深度超声治疗的系统和方法
公开(公告)号：US07824348B2
公开(公告)日：2010-11-02
申请号：US10944500
申请日：2004-09-16
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B17/22
CPC分类号： A61N7/00 , A61B34/30 , A61B2017/22024 , A61B2017/22028 , A61N2007/0065 , A61N2007/0069 , A61N2007/0073 , A61N2007/0095
摘要： A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.
摘要翻译：非侵入性可变深度超声治疗方法和系统包括被配置为向患者提供超声治疗的可变深度换能器系统。示例性可变深度换能器系统可以包括被配置为向多于一个感兴趣的区域提供治疗的换能器，例如感兴趣的深部治疗区域和感兴趣的表面区域和/或感兴趣的皮下区域之间。可变深度换能器可以包括具有压电有源层，匹配层和/或用于产生辐射或声能的其它材料的换能元件。可变深度换能器可以被配置为在大约750kHz至20MHz或更大的范围内的中等频率下操作。另外，换能元件可以配置有可变深度装置，该可变深度装置包括一种或多种材料，其被配置为允许将声能控制和聚焦/散焦到多于一个感兴趣的区域。

24. 发明授权

US07530356B2 Method and system for noninvasive mastopexy 有权
标题翻译：无创乳腺炎的方法和系统
公开(公告)号：US07530356B2
公开(公告)日：2009-05-12
申请号：US11163155
申请日：2005-10-06
申请人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
发明人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
IPC分类号： A61B8/00 , A61B18/04
CPC分类号： A61N7/02 , A61B8/0825 , A61B8/14 , A61B8/4281 , A61B8/429 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B18/04 , A61B18/18 , A61B2018/00333 , A61B2018/00577 , A61B2018/00642 , A61B2018/00791 , A61B2018/00904 , A61B2018/00994 , A61N2007/0052 , G01S7/52046 , G01S15/8909
摘要： Methods and systems for noninvasive mastopexy through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a deep tissue region, such as a region comprising muscular fascia and ligaments. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth from 1 mm to 4 cm with a conformal selective deposition of ultrasound energy without damaging an intervening tissue in the range of frequencies from 1 to 15 MHz. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.
摘要翻译：提供了通过用超声波深部组织收紧进行非侵入性手术的方法和系统。示例性方法和系统包括治疗性超声系统，其被配置为向深部组织区域（例如包括肌肉筋膜和韧带的区域）提供超声治疗。根据各种示例性实施例，治疗性超声系统可以被配置为通过适形选择性沉积超声能量来实现从1mm到4cm的深度，而不损害在1至15MHz的频率范围内的介入组织。此外，治疗性超声还可以与超声成像或成像/监测能力组合，或者单独配置成像，治疗和监测系统或其任何一体化的结合。

25. 发明申请

US20080281255A1 METHODS AND SYSTEMS FOR MODULATING MEDICANTS USING ACOUSTIC ENERGY 有权
标题翻译：使用声学能量调制药物的方法和系统
公开(公告)号：US20080281255A1
公开(公告)日：2008-11-13
申请号：US12116810
申请日：2008-05-07
申请人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
发明人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
IPC分类号： A61N7/00
CPC分类号： A61M37/0092 , A61B8/4281 , A61B2090/378 , A61M2037/0007 , A61M2205/3375 , A61N7/00 , A61N7/02 , A61N2007/0008 , A61N2007/0043 , A61N2007/0056
摘要： This invention provides methods and systems uniquely capable of enhancing medicant delivery and/or effectiveness through the use of energy to predictably disrupt membranes and mechanically and thermally modulate cells and tissues. In exemplary embodiments, the methods and systems disclosed herein are capable of modulating multiple layers of tissue. In an exemplary embodiment, the energy is acoustic energy (e.g., ultrasound). In other exemplary embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents, or various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling. Medicants can be first introduced to the region of interest by diffusion, circulation, and/or injection. An exemplary system for enhancing medicant delivery and/or effectiveness comprises a control system, a probe, and a display or indicator system. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.
摘要翻译：本发明提供了能够通过使用能量来预测性地破坏膜并机械和热调节细胞和组织来增强药物递送和/或有效性的方法和系统。在示例性实施例中，本文公开的方法和系统能够调制多层组织。在示例性实施例中，能量是声能（例如，超声）。在其它示例性实施例中，能量是基于光子的能量（例如，IPL，LED，激光，白光等）或其他能量形式，例如射频电流，或声能，电磁能和其他能量的各种组合形式或能量吸收器如冷却。首先通过扩散，循环和/或注射将药物引入感兴趣的区域。用于增强药物递送和/或有效性的示例性系统包括控制系统，探针和显示器或指示器系统。可以与本发明预期的超声系统可以联接和/或共同成像和/或监视。

26. 发明授权

US07393325B2 Method and system for ultrasound treatment with a multi-directional transducer 失效
标题翻译：用多向传感器进行超声处理的方法和系统
公开(公告)号：US07393325B2
公开(公告)日：2008-07-01
申请号：US10944499
申请日：2004-09-16
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B8/00
CPC分类号： A61N7/022 , A61B8/4272 , A61B2017/00084 , A61B2090/378 , A61N2007/0078
摘要： A method and system for ultrasound treatment utilizing a multi-directional transducer to facilitate treatment, such as therapy and/or imaging or other tissue parameter monitoring, in two or more directions. In accordance with an exemplary embodiment, a multi-directional transducer comprises a transduction element configured to provide for ultrasound energy, such as radiation, acoustical energy, heat energy, imaging, positional information and/or tissue parameter monitoring signals in two or more directions. The transduction element can comprise various materials for providing ultrasound energy or radiation, such as piezoelectric materials, with and without matching layers. In addition, the transduction element can be configured for substantially uniform, focused and/or defocused radiation patterns, as well as for single, multiple-element and/or multiple-element array configurations. In addition, an exemplary multi-directional transducer can comprise multiple elements, either side by side, stacked or in an array.
摘要翻译：一种利用多向换能器来促进诸如在两个或更多个方向上的治疗和/或成像或其它组织参数监测的治疗的超声治疗的方法和系统。根据示例性实施例，多方向换能器包括换能元件，其被配置成在两个或更多个方向上提供超声能量，例如辐射，声能，热能，成像，位置信息和/或组织参数监测信号。转导元件可以包括用于提供超声能量或辐射的各种材料，例如具有和不具有匹配层的压电材料。此外，转导元件可以被配置为基本上均匀的，聚焦的和/或散焦的辐射图，以及用于单个，多元件和/或多元件阵列配置。此外，示例性多向换能器可以包括多个元件，并排，堆叠或阵列。

27. 发明授权

US07247141B2 Intra-cavitary ultrasound medical system and method 有权
标题翻译：腔内超声医疗系统及方法
公开(公告)号：US07247141B2
公开(公告)日：2007-07-24
申请号：US10795680
申请日：2004-03-08
申请人： Inder Raj S. Makin , Yoav Avidor , Michael H. Slayton , Peter G. Barthe
发明人： Inder Raj S. Makin , Yoav Avidor , Michael H. Slayton , Peter G. Barthe
IPC分类号： A61B8/00
CPC分类号： A61B17/42 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B17/2202 , A61B2017/2253 , A61B2017/4216
摘要： A method for medically employing ultrasound within a body cavity of a patient. An end effector is obtained having a medical ultrasound transducer assembly. A biocompatible hygroscopic substance is obtained having a non-expanded anhydrous state and having an expanded and fluidly-loculated hydrated state. The end effector, including the transducer assembly, and the substance in substantially its anhydrous state are inserted into a body cavity (such as endoscopically inserted into a uterus) of a patient. The transducer assembly is used to medically image and/or medically treat patient tissue (such as stopping blood flow to, and/or ablating, a uterine fibroid). A system for medically employing ultrasound includes the end effector and the substance. In another system, the end effector includes the substance. The substance in its hydrated state expands inside the body cavity providing acoustic coupling between the wall of the body cavity and the transducer assembly.
摘要翻译：一种在患者体腔内医用超声波的方法。获得具有医学超声换能器组件的端部执行器。获得具有未膨胀无水状态并且具有膨胀和流动位置的水合状态的生物相容性吸湿性物质。末端执行器（包括换能器组件）和基本上其无水状态的物质插入患者的体腔（例如内窥镜插入子宫中）。换能器组件用于医疗图像和/或医学上治疗患者组织（例如阻止血液流向和/或消融子宫肌瘤）。用于医学使用超声波的系统包括末端执行器和物质。在另一系统中，末端执行器包括物质。其水合状态的物质在体腔内扩张，提供体腔壁与换能器组件之间的声耦合。

28. 发明授权

US06213948B1 Apparatus for three dimensional ultrasound imaging 有权
标题翻译：三维超声成像装置
公开(公告)号：US06213948B1
公开(公告)日：2001-04-10
申请号：US09523890
申请日：2000-03-13
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B812
CPC分类号： A61B8/483 , A61B8/00 , A61B8/14 , A61B8/4461 , Y10S128/916
摘要： A method and apparatus for medical diagnostic ultrasound imaging that utilizes a one, one and one-half or two dimensional scanhead for performing three dimensional imaging. The method and apparatus limits acoustic reverberations by swinging or rotating an array of ultrasound transducer elements about the longitudinal axis of the probe of an ultrasound transducer apparatus to enable the transducers to maintain a constant and concentric position with the acoustic membrane of the probe.
摘要翻译：一种用于医学诊断超声成像的方法和装置，其利用一个一个或二个或二维扫描头进行三维成像。该方法和装置通过围绕超声换能器装置的探针的纵向轴线摆动或旋转超声波换能器元件阵列来限制声学混响，以使换能器能够与探针的声膜保持恒定和同心的位置。

29. 发明授权

US06036646A Method and apparatus for three dimensional ultrasound imaging 失效
标题翻译：三维超声成像的方法和装置
公开(公告)号：US06036646A
公开(公告)日：2000-03-14
申请号：US113227
申请日：1998-07-10
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B8/00 , A61B8/14
CPC分类号： A61B8/483 , A61B8/00 , A61B8/14 , A61B8/4461 , Y10S128/916
摘要： A method and apparatus for medical diagnostic ultrasound imaging that utilizes a one, one and one-half or two dimensional scanhead for performing three dimensional imaging. The method and apparatus limits acoustic reverberations by swinging or rotating an array of ultrasound transducer elements about the longitudinal axis of the probe of an ultrasound transducer apparatus to enable the transducers to maintain a constant and concentric position with the acoustic membrane of the probe.
摘要翻译：一种用于医学诊断超声成像的方法和装置，其利用一个一个或二个或二维扫描头进行三维成像。该方法和装置通过围绕超声换能器装置的探针的纵向轴线摆动或旋转超声波换能器元件阵列来限制声学混响，以使换能器能够与探针的声膜保持恒定和同心的位置。

30. 发明授权

US10537304B2 Hand wand for ultrasonic cosmetic treatment and imaging 有权
公开(公告)号：US10537304B2
公开(公告)日：2020-01-21
申请号：US12996616
申请日：2009-06-05
申请人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
发明人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
IPC分类号： A61B8/08
摘要： Embodiments of the invention provide a dermatological cosmetic treatment and imaging system and method. In some embodiments, the system (20) includes a hand wand (100) with at least one finger activated controller (150, 160), and a removable transducer module (200) having an ultrasound transducer (280). In some embodiments, the system (20) can include a control module (300) that is coupled to the hand wand (100) and has a graphical user interface (310) for controlling the removable transducer module (200), and an interface (130) coupling the hand wand (100) to the control module (300). The interface (130) may provide power to the hand wand or may transfer a signal from the hand wand to the control module. In some embodiments, the cosmetic treatment system (20) may be used in cosmetic procedures on at least a portion of a face, head, neck, and/or other part of a patient.

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