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21. 发明申请

US20090192385A1 Method and system for virtual roadmap imaging 审中-公开
标题翻译：虚拟路线图成像方法与系统
公开(公告)号：US20090192385A1
公开(公告)日：2009-07-30
申请号：US12011291
申请日：2008-01-25
申请人： Oliver Meissner , John C. Rauch
发明人： Oliver Meissner , John C. Rauch
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B5/062 , A61B5/721 , A61B5/7289 , A61B6/032 , A61B6/12 , A61B6/4441 , A61B6/481 , A61B6/507 , A61B6/5288 , A61B8/0833 , A61B8/5276
摘要： A system and method of producing virtual roadmap image of a patient is described. CT-like image data may be obtained for a patient, with or without a contrast agent, and differenced so as to form a roadmap mask. The roadmap mask is in the form of a 2-dimensional digitally reconstructed radiograph from the same orientation as that of a fluoroscopic X-ray device which takes real-time images of the patient during treatment. The fluoroscopic image may be subtracted from the roadmap mask so as to more clearly visualize the position of a catheter introduced into the patient for treatment. When the orientation of the fluoroscopic image is changed during the course of treatment, the roadmap mask image for the corresponding orientation is used.
摘要翻译：描述了一种产生患者的虚拟路线图图像的系统和方法。可以获得具有或不具有造影剂的患者的CT样图像数据，并且被差分以形成路线图掩模。路线图掩模是以与在治疗期间拍摄患者的实时图像的荧光X射线装置相同取向的二维数字重建的X光片的形式。可以从路线图掩模中减去透视图像，以便更清楚地将引入患者的导管的位置可视化以进行治疗。当在治疗过程中荧光镜像的方向改变时，使用用于相应取向的路线图掩模图像。

22. 发明申请

US20090003521A1 Optimized clinical workflow for combined 2D/3D morphological and functional coronary interventions using a robotic angiography system 审中-公开
标题翻译：使用机器人血管造影系统优化组合2D / 3D形态和功能性冠状动脉介入治疗的临床工作流程
公开(公告)号：US20090003521A1
公开(公告)日：2009-01-01
申请号：US11824334
申请日：2007-06-28
申请人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/5235
摘要： A method of optimized diagnosis and treatment of suspected myocardial infarctions is described. The patient having possible coronary artery disease is transferred to a treatment room with an imaging modality suitable for obtaining computed tomographic (CT)-like images. Such images are obtained as radiographic image data, with or without contrast agent, and used in the medical diagnosis. If minimally invasive therapy such as percutaneous transluminal coronal angioplasty (PTCA) is indicated, the patient is prepared for the procedure in the same room, and the procedure performed, where the imaging modality is used to obtain fluoroscopic images to guide the PTCA procedure, or to assess the results of the procedure. The imaging modality may be mounted to a first positioning robot, and a second robot may facilitate the positioning or movement of the patient.
摘要翻译：描述了可疑心肌梗死的优化诊断和治疗方法。具有可能的冠状动脉疾病的患者被转移到具有适于获得计算机断层摄影（CT）样图像的成像模式的治疗室。这样的图像作为放射照相图像数据获得，具有或不具有造影剂，并且用于医学诊断。如果显示微创治疗如经皮腔内冠状动脉血管成形术（PTCA），则患者准备在同一房间中的手术，并且执行该过程，其中使用成像模式获得荧光镜图像以引导PTCA程序，或评估程序的结果。成像模式可以安装到第一定位机器人，并且第二机器人可以促进患者的定位或移动。

23. 发明申请

US20070073364A1 Combined OCT catheter device and method for combined optical coherence tomography (OCT) diagnosis and photodynamic therapy (PDT) 审中-公开
标题翻译：组合OCT导管装置和组合光学相干断层扫描（OCT）诊断和光动力治疗（PDT）的方法
公开(公告)号：US20070073364A1
公开(公告)日：2007-03-29
申请号：US11239608
申请日：2005-09-29
申请人： Oliver Meissner , Martin Ostermeier , Martin Hoheisel
发明人： Oliver Meissner , Martin Ostermeier , Martin Hoheisel
IPC分类号： A61N5/06 , A61B6/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0084 , A61N5/0601 , A61N5/062 , A61N2005/0609
摘要： In a catheter device and a method for in vivo activation of a photosensitizing drug in a vessel, endovascular tissue, and/or intraluminal tissue, a catheter carrying both an optical coherence tomography (OCT) lens, from which OCT imaging light is emitted, and a photodynamic therapy (PDT) lens from which photosensitizing drug-activating light is emitted, is inserted into a vessel containing a lesion to be treated. A photosensitizing drug is caused to be placed in the vessel as well, such as in the form of a coating on a stent or a coating on an exterior of a balloon carried by the catheter. Light is emitted from the PDT lens to activate the photosensitizing drug while light is simultaneously emitted from the OCT lens to obtain an OCT image to monitor the drug activation.
摘要翻译：在导管装置和用于体内活化容器，血管内组织和/或管腔内组织中的光敏药物的方法中，携带OCT成像光的光学相干断层摄影（OCT）透镜的导管以及将光敏感药物激活光发射的光动力疗法（PDT）镜片插入含有待治疗病变的容器中。导致光敏药物也被放置在容器中，例如以支架的形式或由导管承载的球囊的外部上的涂层的形式。光从PDT透镜发射以激活光敏药物，同时从OCT镜片同时发出光，以获得OCT图像以监测药物激活。

24. 发明申请

US20070065080A1 Optical coherence tomography system 有权
标题翻译：光学相干断层扫描系统
公开(公告)号：US20070065080A1
公开(公告)日：2007-03-22
申请号：US11523395
申请日：2006-09-19
申请人： Estelle Camus , Oliver Meissner , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Thomas Redel
IPC分类号： G02B6/04
CPC分类号： A61B5/6852 , A61B5/0066 , G02B6/04 , G02B6/4249
摘要： An optical coherence tomography system includes a catheter in which is arranged a plurality of light conducting fibers. It further includes a plurality of optical units. Light from the proximal end to the distal end and signals from the distal end to the proximal end can be transmitted simultaneously in different fibers. Time is saved through the simultaneous signal processing of signals from different fibers. That is advantageous particularly in the imaging, by means of coherence tomography, of blood vessels that have to be occluded for said imaging.
摘要翻译：光学相干断层摄影系统包括其中布置有多个导光纤维的导管。它还包括多个光学单元。从近端到远端的光和从远端到近端的信号可以在不同的纤维中同时传播。通过来自不同光纤的信号的同时信号处理来节省时间。这是有利的，特别是在通过相干断层摄影技术对必须被遮挡以用于所述成像的血管的成像中。

25. 发明授权

US09067786B2 Primary reformer with secondary inlet channels supplying the burner 有权
标题翻译：具有辅助进气道的初级重整器供应燃烧器
公开(公告)号：US09067786B2
公开(公告)日：2015-06-30
申请号：US12451012
申请日：2008-03-22
申请人： Oliver Meissner , Silke Wodberg
发明人： Oliver Meissner , Silke Wodberg
IPC分类号： B01J7/00 , C01B3/38 , B01J8/06 , F23C5/00 , F23C7/00 , F23D23/00
CPC分类号： C01B3/384 , B01J8/062 , B01J2208/00495 , B01J2208/00504 , B01J2208/00548 , C01B2203/0233 , C01B2203/0816 , C01B2203/0822 , C01B2203/1235 , C01B2203/1695 , F23C5/00 , F23C7/00 , F23D23/00 , Y02P20/128
摘要： The invention relates to a reactor for catalytic reformation of hydrocarbons with steam at elevated pressure, said reactor comprising a reaction space and a fire space, said reaction space comprised of a multitude of vertical tubes arranged in rows and suitable for being filled with a catalyst, and having facilities for feeding hydrocarbons and steam to be reformed to the reaction space, and furthermore comprising facilities for discharge of reformed synthesis gas from the reaction space, and furthermore comprising a multitude of firing facilities in the upper area of the firing space, said firing facilities being able to generate mainly downwardly directed flames that are suitable to heat the aforementioned reaction tubes, with the tube feeding air to the burner being equipped with a facility for adjusting and setting the air flow, and there being a secondary air feeder mounted additionally to this tube and branching-off from it and configured in various layouts and having an independently controllable facility for adjusting and setting the air flow and also feeding air to the firing device so that a more favorable ratio of fuel gas versus air results at the burners so as to be able to achieve a waste gas poor in nitric oxides.
摘要翻译：本发明涉及一种用于在升高的压力下用蒸汽催化重整烃的反应器，所述反应器包括反应空间和火焰空间，所述反应空间由排列成行并适于填充催化剂的多个垂直管组成，并且具有用于将碳氢化合物和蒸汽进料至反应空间的设备，并且还包括从反应空间排出重整合成气的设备，并且还包括在燃烧空间的上部区域中的多个焙烧设备，设备能够主要产生适合于加热上述反应管的向下定向的火焰，管中将空气供给燃烧器配备有用于调节和设定气流的设备，并且还有一个辅助空气供给器，该管并从其分支并且以各种布局配置并具有独立性用于调节和设定空气流的可控设备，并且还将空气供给到点火装置，使得在燃烧器处产生更有利的燃料气体与空气的比率，以便能够实现一氧化氮中的贫气。

26. 发明授权

US08386019B2 Arrangement for supporting a percutaneous intervention 有权
标题翻译：支持经皮干预的安排
公开(公告)号：US08386019B2
公开(公告)日：2013-02-26
申请号：US12070885
申请日：2008-02-21
申请人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
IPC分类号： A61B5/05
CPC分类号： A61B34/70 , A61B34/30 , A61B2017/00699 , A61B2017/00703 , A61B2090/364 , A61B2090/376 , A61B2090/3762
摘要： The invention relates to an arrangement for assisting a percutaneous intervention, comprising an imaging system for tomographic imaging, a robot registered therewith and devices for capturing movements of the patient. A processing unit registers a 4D image dataset recorded before the intervention with a 2D or 3D image dataset of the patient which was recorded immediately before the intervention by the imaging system at a defined respiratory position. From this image data, the access path is transmitted to the robot as a function of the movements captured during recording the 4D image dataset and registration, said robot in turn, depending on the instantaneous movement data, holding the instrument on a predetermined target path and preventing the instrument from being advanced by the person if and as long as the instantaneous movement data does not match the previously recorded movement data. The arrangement reduces the risk of puncture errors.
摘要翻译：本发明涉及一种用于辅助经皮干预的装置，包括用于层析成像的成像系统，与其注册的机器人以及用于捕获患者运动的装置。处理单元将在介入之前记录的4D图像数据集与由被成像系统干预的紧急记录在定义的呼吸位置之间的患者的2D或3D图像数据集进行注册。根据该图像数据，根据记录4D图像数据集并记录时记录的运动的函数，根据瞬时移动数据将仪器保持在预定的目标路径上，将访问路径传送到机器人，并且如果和瞬时移动数据与先前记录的移动数据不匹配，则防止该仪器被人推进。该布置降低了穿刺错误的风险。

27. 发明授权

US07778453B2 Multi-modality method and software for representation and evaluation of extremity exposures of arthritis/arthrosis patients 失效
标题翻译：用于表达和评估关节炎/关节病患者肢体暴露的多模态方法和软件
公开(公告)号：US07778453B2
公开(公告)日：2010-08-17
申请号：US11668566
申请日：2007-01-30
申请人： Estelle Camus , Oliver Meissner
发明人： Estelle Camus , Oliver Meissner
IPC分类号： G06K9/00
CPC分类号： G06F19/321 , A61B5/015 , A61B5/4528 , A61B6/505 , A61B6/5247 , A61B8/0875 , A61B8/4416 , A61B2090/364 , G06F19/00
摘要： In a multi-modality method for representing functional and morphological exposures of an extremity of patients exhibiting arthritis/arthrosis, and corresponding computer software, images obtained with different imaging modalities are supplied to a computer and displayed at the computer with a default line model of the extremity superimposed on each of the images. A user interacts with the computer to modify the line model as necessary, so that each of the images has a modified line model associated therewith. The images obtained from the different imaging modalities are then superimposed and registered with each other by conforming the respective modified line models with each other. One of the images can be composed of a number of sub-images, obtained at respective joints in the extremity. These individual images of the joint can be fused with the image of the complete extremity, so that in a display of such a fused image, the individual joint images can be selected and displayed.
摘要翻译：在用于表示出现关节炎/关节炎的患者的肢体的功能和形态学曝光的多模态方法以及相应的计算机软件中，用不同成像模态获得的图像被提供给计算机并且在计算机上显示具有肢体叠加在每个图像上。用户与计算机交互以根据需要修改线模型，使得每个图像具有与其相关联的修改的线模型。然后通过使相应的修改线模型相互匹配，将从不同成像模态获得的图像叠加并对齐。一个图像可以由在肢体中的各个关节处获得的多个子图像组成。关节的这些单独的图像可以与完整肢体的图像融合，使得在这样的融合图像的显示中，可以选择和显示各个关节图像。

28. 发明申请

US20080292049A1 Device for obtaining perfusion images 有权
标题翻译：用于获得灌注图像的装置
公开(公告)号：US20080292049A1
公开(公告)日：2008-11-27
申请号：US11804903
申请日：2007-05-21
申请人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
发明人： Estelle Camus , Thomas Redel , Martin Ostermeier , Oliver Meissner
IPC分类号： A61B6/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503 , A61B6/507 , G06F19/00 , G06F19/321
摘要： A system and method for obtaining perfusion images is disclosed. The system and method includes hardware and software for determining physiological characteristics of a patient and determining imaging parameter values for an imaging modality based on the patient's physiological characteristics. The system also includes a controller operative to receive the imaging parameter values for controlling an X-ray device. The X-ray device is coupled with the controller and acquires projection images of the patient, and outputs the projection images to a perfusion evaluation computer for evaluating the perfusion of an region of interest represented in the projection images. The perfusion rate of the region of interest is then output to an output device, such as a display or printer.
摘要翻译：公开了一种用于获得灌注图像的系统和方法。该系统和方法包括用于确定患者生理特征的硬件和软件，并且基于患者的生理特征确定成像模态的成像参数值。该系统还包括可操作以接收用于控制X射线装置的成像参数值的控制器。 X射线装置与控制器耦合并获取患者的投影图像，并将投影图像输出到灌注评估计算机，以评估在投影图像中表示的感兴趣区域的灌注。然后将感兴趣区域的灌注速率输出到诸如显示器或打印机的输出装置。

29. 发明申请

US20080292046A1 Bronchopulmonary medical services system and imaging method 审中-公开
标题翻译：支气管肺内医疗服务系统及成像方法
公开(公告)号：US20080292046A1
公开(公告)日：2008-11-27
申请号：US12150581
申请日：2008-04-29
申请人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
IPC分类号： A61B6/00 , A61B5/05
CPC分类号： A61B1/2676 , A61B6/032 , A61B6/4417 , A61B6/4441 , A61B6/4458 , A61B6/481 , A61B6/504 , A61B6/5247 , A61B8/12 , A61B10/04 , A61B34/20 , A61B34/30 , A61B90/36 , A61B2034/2051 , A61B2090/364 , A61B2090/376 , A61B2090/3762 , A61B2090/3764
摘要： A bronchopulmonary medical services system is provided in order to offer medical services to a patient in a single location. In one aspect, the system is provided with a patient alignment device and a C-arm imaging device. A medical services suite may be equipped with various medical service devices such that the patient receives medical services in a single location.
摘要翻译：提供支气管肺内医疗服务系统以便在单个位置向患者提供医疗服务。在一个方面，该系统设置有患者对准装置和C形臂成像装置。医疗服务套件可以配备有各种医疗服务设备，使得患者在单个位置接收医疗服务。

30. 发明申请

US20080208212A1 Arrangement for supporting a percutaneous intervention 有权
标题翻译：支持经皮干预的安排
公开(公告)号：US20080208212A1
公开(公告)日：2008-08-28
申请号：US12070885
申请日：2008-02-21
申请人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
发明人： Estelle Camus , Oliver Meissner , Martin Ostermeier , Thomas Redel
IPC分类号： A61B19/00
CPC分类号： A61B34/70 , A61B34/30 , A61B2017/00699 , A61B2017/00703 , A61B2090/364 , A61B2090/376 , A61B2090/3762
摘要： The invention relates to an arrangement for assisting a percutaneous intervention, comprising an imaging system for tomographic imaging, a robot registered therewith and devices for capturing movements of the patient. A processing unit registers a 4D image dataset recorded before the intervention with a 2D or 3D image dataset of the patient which was recorded immediately before the intervention by the imaging system at a defined respiratory position. From this image data, the access path is transmitted to the robot as a function of the movements captured during recording the 4D image dataset and registration, said robot in turn, depending on the instantaneous movement data, holding the instrument on a predetermined target path and preventing the instrument from being advanced by the person if and as long as the instantaneous movement data does not match the previously recorded movement data. The arrangement reduces the risk of puncture errors.
摘要翻译：本发明涉及一种用于辅助经皮干预的装置，包括用于层析成像的成像系统，与其注册的机器人以及用于捕获患者运动的装置。处理单元将在介入之前记录的4D图像数据集与由被成像系统干预的紧急记录在定义的呼吸位置之间的患者的2D或3D图像数据集进行注册。根据该图像数据，根据记录4D图像数据集并记录时记录的运动的函数，根据瞬时移动数据将仪器保持在预定的目标路径上，将访问路径传送到机器人，并且如果和瞬时移动数据与先前记录的移动数据不匹配，则防止该仪器被人推进。该布置降低了穿刺错误的风险。

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