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21. 发明申请

US20100137947A1 PATIENT PROGRAMMER WITH AUTOMATED MRI COMPATIBILITY VERIFICATION FOR ACTIVE IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：具有动态可植入医疗设备的自动MRI兼容性验证的患者编程器
公开(公告)号：US20100137947A1
公开(公告)日：2010-06-03
申请号：US12626374
申请日：2009-11-25
申请人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
发明人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
IPC分类号： A61N1/08
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G06F19/00 , G16H40/40
摘要： A system may include an active implantable medical device implantable in a body of a patient and a patient programmer for the AIMD. The patient programmer may be configured to obtain magnetic resonance imaging (MRI) compatibility information relating to compatibility of the AIMD with an MRI modality.
摘要翻译：系统可以包括可植入患者体内的有源可植入医疗装置和用于AIMD的患者编程器。患者程序员可被配置为获得与AIMD与MRI模态的兼容性相关的磁共振成像（MRI）兼容性信息。

22. 发明申请

US20100137946A1 PATIENT-CENTRIC DATA COLLECTION FOR AUTOMATED MRI COMPATIBILITY VERIFICATION 审中-公开
标题翻译：患者中心数据采集自动MRI兼容性验证
公开(公告)号：US20100137946A1
公开(公告)日：2010-06-03
申请号：US12626354
申请日：2009-11-25
申请人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
发明人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
IPC分类号： A61N1/08
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G06F19/00 , G16H40/40
摘要： A system may include a patient information terminal that receives magnetic resonance imaging compatibility information from a patient and a processor that automatically determines compatibility of an active implantable medical device with an magnetic resonance imaging modality based on the magnetic resonance imaging compatibility information. The magnetic resonance imaging compatibility information includes information relating to compatibility of the active implantable medical device implantable in the patient and the magnetic resonance imaging modality.
摘要翻译：系统可以包括从患者和处理器接收磁共振成像兼容性信息的患者信息终端，所述处理器基于磁共振成像兼容性信息自动确定有源可植入医疗装置与磁共振成像模态的兼容性。磁共振成像兼容性信息包括与可植入患者的有源可植入医疗装置与磁共振成像模式的兼容性有关的信息。

23. 发明申请

US20100137945A1 AUTOMATED VERIFICATION OF MRI COMPATIBILITY OF ACTIVE IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：自动验证活动可植入医疗器械的MRI兼容性
公开(公告)号：US20100137945A1
公开(公告)日：2010-06-03
申请号：US12626342
申请日：2009-11-25
申请人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
发明人： Hrishikesh Gadagkar , James Zimmerman , James M. Olsen , Robyn L. Jagler , Timothy R. Abraham , Jeffrey R. Dixon
IPC分类号： A61N1/08
CPC分类号： A61N1/37264 , A61B5/055 , A61N1/086 , A61N1/3718 , A61N1/372 , A61N1/37247 , A61N1/37258 , A61N1/37282 , A61N1/3925 , G01R33/285 , G01R33/288 , G06F19/00 , G16H40/40
摘要： A system may include a processor configured to automatically obtain magnetic resonance imaging compatibility information relating to compatibility of an active implantable medical device implantable in a patient with an MRI modality from at least two information sources. The processor may also be configured to automatically determine compatibility of the active implantable medical device with the magnetic resonance imaging modality based on the magnetic resonance imaging compatibility information.
摘要翻译：系统可以包括处理器，其被配置为自动获得与可植入患者的有源可植入医疗装置与来自至少两个信息源的MRI模态的兼容性相关的磁共振成像兼容性信息。处理器还可以被配置为基于磁共振成像兼容性信息自动确定主动植入式医疗装置与磁共振成像模态的兼容性。

24. 发明授权

US07931643B2 Miniature pump for drug delivery 有权
标题翻译：用于药物递送的微型泵
公开(公告)号：US07931643B2
公开(公告)日：2011-04-26
申请号：US11490876
申请日：2006-07-21
申请人： James M. Olsen , Mark S. Lent , James G. Skakoon , Richard T. Stone , Laetitia Mayor , Dale F. Seeley , Michael T. Hegland
发明人： James M. Olsen , Mark S. Lent , James G. Skakoon , Richard T. Stone , Laetitia Mayor , Dale F. Seeley , Michael T. Hegland
IPC分类号： A61K9/22 , A61M37/00 , A61F5/00
CPC分类号： A61M5/14276 , A61M5/14593 , A61M5/16881 , A61M39/0208 , A61M2039/0205 , A61M2205/0266
摘要： A miniature drug delivery pump utilizes a shape memory Ni—Ti alloy. A flow restrictor is provided and the pump is refillable.
摘要翻译：微型药物输送泵采用形状记忆Ni-Ti合金。提供了一个流量限制器，并且该泵是可再填充的。

25. 发明申请

US20080269854A1 IMPLANTABLE MEDICAL LEAD WITH MULTIPLE ELECTRODE CONFIGURATIONS 有权
标题翻译：具有多个电极配置的可植入医疗引线
公开(公告)号：US20080269854A1
公开(公告)日：2008-10-30
申请号：US11740643
申请日：2007-04-26
申请人： Michael T. Hegland , James M. Olsen , Gabriela C. Miyazawa , Richard T. Stone
发明人： Michael T. Hegland , James M. Olsen , Gabriela C. Miyazawa , Richard T. Stone
IPC分类号： A61N1/05
CPC分类号： A61N1/0534 , A61N1/36082
摘要： Medical leads having at least one segmented row of electrodes, as well as at least one ring electrode that extends substantially completely around the periphery of the lead, are described. The electrodes in a segmented row extend around only a portion of the periphery of the lead, rather than substantially around the entire periphery. The electrodes in a segmented row may be distributed at respective locations around the periphery of the lead and separated by insulating material. The ring electrodes and segmented rows are located at respective axial positions. For example, in some embodiments, a plurality of segmented rows, such as two rows having three electrodes each, are located between two ring electrodes. Such a lead may, for example, provide a variety of stimulation modalities because of localized stimulation capabilities.
摘要翻译：描述了具有至少一个分段的电极列的医疗引线以及基本上完全围绕引线的周边延伸的至少一个环形电极。分段行中的电极仅围绕引线周边的一部分延伸，而不是基本上围绕整个周边延伸。分段行中的电极可以分布在引线的周围的相应位置处并被绝缘材料隔开。环形电极和分段行位于相应的轴向位置。例如，在一些实施例中，多个分段行（例如具有三个电极的两行）分布在两个环形电极之间。例如，这样的引线可以由于局部刺激能力而提供各种刺激模式。

26. 发明申请

US20120041529A1 ESTABLISHING CONTINUITY BETWEEN A SHIELD WITHIN AN IMPLANTABLE MEDICAL LEAD AND A SHIELD WITHIN AN IMPLANTABLE LEAD EXTENSION 有权
标题翻译：建立在可植入医疗领域之间的屏障和可伸缩引线延伸中的屏蔽之间的连续性
公开(公告)号：US20120041529A1
公开(公告)日：2012-02-16
申请号：US13265249
申请日：2010-04-28
申请人： James M. Olsen , Bruce R. Mehdizadeh , Michael J. Kern
发明人： James M. Olsen , Bruce R. Mehdizadeh , Michael J. Kern
IPC分类号： A61N1/00 , H01B19/00
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Implantable medical leads and implantable lead extensions include a shield. The implantable medical lead is coupled to the implantable lead extension. Stimulation electrodes of the implantable medical lead contact stimulation connectors within a housing of the implantable extension to establish a conductive pathway for stimulation signals from filars of the implantable extension to filars of the implantable medical lead. Continuity is established between the shield of the implantable medical lead and the implantable extension by providing a radio frequency conductive pathway within the housing. The radio frequency conductive pathway extends from a shield of the implantable extension to a shield connector that contacts a shield electrode of the implantable medical lead. The radio frequency conductive pathway may have various forms such as a jumper wire or an extension of the shield within the implantable extension.
摘要翻译：植入式医疗引线和可植入引线延伸部分包括一个护罩。可植入医疗引线连接到可植入引线延伸部。植入式医疗引线接触刺激连接器的刺激电极在可植入的延伸部的壳体内，以建立用于刺激从可植入的延伸部的丝状体到可植入医疗引线的丝线的信号的导电通路。通过在壳体内提供射频导电通路，在可植入医疗引线的屏蔽和可植入的延伸部之间建立连续性。射频导电路径从可植入延伸部的屏蔽延伸到接触可植入医疗引线的屏蔽电极的屏蔽连接器。射频导电路径可以具有各种形式，例如跨接线或可植入延伸部内的护罩的延伸部。

27. 发明授权

US09002474B2 Establashing continuity between a shield within an implantable medical lead and a shield within an implantable lead extension 有权
标题翻译：建立植入式医疗引线内的屏蔽和可植入引线延伸部内的屏蔽之间的连续性
公开(公告)号：US09002474B2
公开(公告)日：2015-04-07
申请号：US13265249
申请日：2010-04-28
申请人： James M. Olsen , Bruce R. Mehdizadeh , Michael J. Kern
发明人： James M. Olsen , Bruce R. Mehdizadeh , Michael J. Kern
IPC分类号： A61N1/00 , A61N1/08 , A61N1/05 , A61N1/37 , A61N1/375 , A61B19/00
CPC分类号： A61N1/08 , A61B90/39 , A61B2090/3966 , A61N1/05 , A61N1/0551 , A61N1/086 , A61N1/3718 , A61N1/3752 , A61N2001/058 , A61N2001/0582 , A61N2001/086 , Y10T29/49016 , Y10T29/49117 , Y10T29/4921 , Y10T29/49227 , Y10T29/49826
摘要： Implantable medical leads and implantable lead extensions include a shield. The implantable medical lead is coupled to the implantable lead extension. Stimulation electrodes of the implantable medical lead contact stimulation connectors within a housing of the implantable extension to establish a conductive pathway for stimulation signals from filars of the implantable extension to filars of the implantable medical lead. Continuity is established between the shield of the implantable medical lead and the implantable extension by providing a radio frequency conductive pathway within the housing. The radio frequency conductive pathway extends from a shield of the implantable extension to a shield connector that contacts a shield electrode of the implantable medical lead. The radio frequency conductive pathway may have various forms such as a jumper wire or an extension of the shield within the implantable extension.
摘要翻译：植入式医疗引线和可植入引线延伸件包括一个护罩。可植入医疗引线连接到可植入引线延伸部。植入式医疗引线接触刺激连接器的刺激电极在可植入的延伸部的外壳内，以建立用于刺激来自可植入的延伸部的丝线到可植入医疗引线的丝束的信号的导电通路。通过在壳体内提供射频导电通路，在可植入医疗引线的屏蔽和可植入的延伸部之间建立连续性。射频导电路径从可植入延伸部的屏蔽延伸到接触可植入医疗引线的屏蔽电极的屏蔽连接器。射频导电路径可以具有各种形式，例如跨接线或可植入延伸部内的护罩的延伸部。

28. 发明授权

US09901284B2 Coordination of functional MRI scanning and electrical stimulation therapy 有权
公开(公告)号：US09901284B2
公开(公告)日：2018-02-27
申请号：US13087736
申请日：2011-04-15
申请人： James M. Olsen , Steven M. Goetz
发明人： James M. Olsen , Steven M. Goetz
IPC分类号： A61B5/055 , A61N1/372 , A61B5/00 , A61N1/362
CPC分类号： A61B5/055 , A61B5/7203 , A61N1/362 , A61N1/37235 , A61N1/37247
摘要： Changes in electrical stimulation therapy delivered via a medical device are coordinated with Functional Magnetic Resonance Imaging (fMRI) scans. In one example, a medical device delivers electrical stimulation therapy to a patient in an MRI unit, where the medical device is configured to cycle electrical stimulation therapy between a plurality of stimulation states. An indication that the medical device will cycle the electrical stimulation therapy or has cycled the electrical stimulation therapy while the patient is in the MRI unit or being imaged by the MRI unit is generated, and an MRI scan of the patient via an MRI workstation is initiated based on the indication. In another example, a medical device detects activation of an MRI scan and automatically switches stimulation states based upon the detection of the MRI scan, such that the scan is associated with a particular stimulation state.

29. 发明授权

US09050455B2 Transverse tripole neurostimulation methods, kits and systems 有权
标题翻译：横向三极神经刺激方法，试剂盒和系统
公开(公告)号：US09050455B2
公开(公告)日：2015-06-09
申请号：US11256220
申请日：2005-10-21
申请人： James M. Olsen , Gary W. King
发明人： James M. Olsen , Gary W. King
IPC分类号： A61N1/00 , A61N1/05 , A61N1/36
CPC分类号： A61N1/0551 , A61N1/36017 , A61N1/36021 , A61N1/3605
摘要： An implantable neurostimulation lead kit adapted for tripolar electric simulation and/or field steering using percutaneously implantable electric stimulation leads. The kit includes three electric stimulation leads that are adapted to provide an electrode array defining, for example, a plurality of electrode sets that may be used to provide tripolar stimulation and/or electric field steering. A method of electrically stimulating the spinal cord is also described.
摘要翻译：一种可植入式神经刺激引线套件，适用于使用经皮植入式电刺激引线的三极电模拟和/或野外转向。套件包括三个电刺激引线，其适于提供限定例如可用于提供三极刺激和/或电场转向的多个电极组的电极阵列。还描述了一种电刺激脊髓的方法。

30. 发明申请

US20120109271A1 REINFORCED SILICONE INSULATION FOR IMPLANTABLE MEDICAL ELECTRICAL LEADS 有权
标题翻译：用于可植入医用电线的增强硅胶绝缘
公开(公告)号：US20120109271A1
公开(公告)日：2012-05-03
申请号：US12915854
申请日：2010-10-29
申请人： Richard Dean Ries , James M. Olsen
发明人： Richard Dean Ries , James M. Olsen
IPC分类号： A61N1/05 , H01B17/00
CPC分类号： A61N1/05
摘要： An improvement to silicone insulation for implantable medical electrical leads includes a plurality of ultra high molecular weight polyethylene multi-filament fibers, wherein each of the plurality includes approximately 25 monofilaments and has a titer of approximately 25. The plurality of fibers are embedded within a wall of the insulation that has a thickness of no greater than approximately 0.008 inch. A first fiber of the plurality preferably extends helically, and a second fiber of the plurality preferably extends linearly such that the second crosses over or under and directly adjacent to the first at a plurality of points, which are spaced apart from one another along an overall length of the silicone insulation. The aforementioned wall thickness is maintained, since, at least at each crossing point of the first and second multi-filament fibers, a coincident cross-section of each of the fibers is compressed in the radial direction.
摘要翻译：用于可植入医疗电引线的硅树脂绝缘的改进包括多个超高分子量聚乙烯复丝纤维，其中多个包含大约25根单丝，并且具有约25的滴定度。多个纤维嵌入在壁的绝缘体，其厚度不大于约0.008英寸。多个第一纤维优选地螺旋地延伸，并且多个第二纤维优选地线性地延伸，使得第二纤维在多个点处彼此间隔开，使得第二条交叉在多个点处彼此间隔开。硅胶绝缘长度。保持上述壁厚，因为至少在第一和第二复丝纤维的每个交叉点处，每个纤维的重合横截面在径向方向上被压缩。

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