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21. 发明申请

US20070275089A1 Argon-based inhalable gaseous medicinal product for the treatment of neurointoxications 审中-公开
标题翻译：氩气可吸入气体药物治疗神经毒素
公开(公告)号：US20070275089A1
公开(公告)日：2007-11-29
申请号：US11836536
申请日：2007-08-09
申请人： Marc Lemaire , Jacques Abraini
发明人： Marc Lemaire , Jacques Abraini
IPC分类号： A61K33/00 , A61P43/00
CPC分类号： A61K33/00
摘要： The invention relates to the use of argon gas for producing all or part of an inhalable medicinal product intended to prevent or treat a neurointoxication in humans. The medicinal product contains argon in an effective proportion and acts on at least one brain receptor in order to regulate the functioning of dopamine-, glutamate-, serotonin-, acetylcholine-, taurine-, GABA- and/or noradrenalin-mediated neurotransmission systems. Preferably, the proportion by volume of argon in the gaseous medicinal product is between 15 and 80%. The neurointoxication is chosen from excitotoxicities engendering a state of addiction, acute cerebral accidents, neurodegenerative diseases, and psychiatric or neurological pathologies, in particular anxiety conditions, psychotic conditions, in particular schizophrenia, and epilepsy in its various forms.
摘要翻译：本发明涉及使用氩气来生产旨在预防或治疗人类神经毒素的全部或部分可吸入药物。药用产品含有有效比例的氩气，并且作用于至少一种脑受体，以调节多巴胺，谷氨酸，5-羟色胺，乙酰胆碱，牛磺酸，GABA和/或去甲肾上腺素介导的神经传递系统的功能。优选地，气态医药产品中的氩气体积比例为15-80％。神经排毒选自产生成瘾状态，急性脑意外，神经变性疾病，精神病学或神经病理学，特别是焦虑症，精神病状况，特别是精神分裂症和各种形式的癫痫的兴奋性毒性。

22. 发明授权

US5028402A Process for separating by means of crown ethers the uranium and plutonium present in an aqueous medium resulting from the reprocessing of irradiated nuclear fuels 失效
标题翻译：通过冠醚分离的方法是由辐射核燃料的后处理产生的水性介质中存在的铀和钚
公开(公告)号：US5028402A
公开(公告)日：1991-07-02
申请号：US367487
申请日：1989-06-16
申请人： Jacques Foos , Pierre Epherre , Alain Guy , Marc Lemaire , Rodolph Chomel , Gerard Cauquil , Pierre Patigny , Alain Vian
发明人： Jacques Foos , Pierre Epherre , Alain Guy , Marc Lemaire , Rodolph Chomel , Gerard Cauquil , Pierre Patigny , Alain Vian
IPC分类号： G21C19/46 , G21F9/04
CPC分类号： G21F9/04
摘要： Process for separating plutonium from uranium contained in a nitric acid aqueous solution from the reprocessing of irradiated fuels comprising plutonium, uranium and fission products by means of crown ethers. Nitric acid aqueous solution (5) containing plutonium, uranium and fission products is contacted at (2) with an organic liquid membrane (3) containing a crown ether. The uranium and plutonium are extracted in the liquid membrane (3) and then transferred by said membrane into a receiving solution (7), which becomes enriched with uranium, because the latter is transferred more rapidly than the plutonium. The crown ether can be DCH 18 C6 or DB 18 C6.
摘要翻译：从含有钚，铀和裂变产物的经辐照燃料后处理的硝酸水溶液中分离钚与铀的方法。含有钚，铀和裂变产物的硝酸水溶液（5）在（2）与含有冠醚的有机液体膜（3）接触。铀和钚在液膜（3）中提取，然后由所述膜转移到富集铀的接收溶液（7）中，因为后者比钚转移得更快。冠醚可以是DCH 18 C6或DB18 C6。

23. 发明授权

US4585079A Method and a machine for handling drill pipes 失效
标题翻译：方法和钻机处理机
公开(公告)号：US4585079A
公开(公告)日：1986-04-29
申请号：US489463
申请日：1983-04-28
申请人： Marc Lemaire , Roland Le Roc'h
发明人： Marc Lemaire , Roland Le Roc'h
IPC分类号： E21B3/04 , E21B19/08 , E21B19/16 , E21B19/20
CPC分类号： E21B19/16 , E21B19/20
摘要： A machine applies screwing and unscrewing torque between successive drill pipes with an essentially vertical axis extending through a tapered opening in a turntable for a well bore. The machine includes a mechanism for applying a high initial unthreading torque and a high final threading torque between successive drill pipes and a mechanism for rapid screwing and unscrewing of successive drill pipes. The machine also includes a clamping mechanism having a bolster and a plurality of shims. The shims have outer portions tapered to fit into the opening of the turntable and have inner portions with a shape corresponding to the shape of the drill pipes. Each shim is supported individually on the bolster by a device that moves the shim into engagement with a drill pipe to grip the same and with sufficient freedom to permit the shims to center the pipe between them automatically. The bolster is lowered to cause the shims to enter the opening in the turntable.
摘要翻译：一台机器在连续的钻杆之间施加螺丝拧紧扭矩，其基本垂直轴线延伸穿过用于井眼的转台中的锥形开口。该机器包括用于在连续的钻杆之间施加高的初始断裂扭矩和高的最终螺纹扭矩的机构以及用于快速拧紧和拧松连续的钻杆的机构。该机器还包括具有摇枕和多个垫片的夹紧机构。垫片具有锥形的外部部分以配合到转台的开口中，并且具有与钻杆的形状对应的形状的内部部分。每个垫片由垫片单独支撑在一起，该装置将垫片移动到与钻杆管接合以夹紧该垫片并具有足够的自由度以允许垫片自动地将管道对中。枕头下降，使垫片进入转盘的开口。

24. 发明申请

US20130039993A1 ARGON-BASED INHALABLE GASEOUS MEDICAMENT AGAINST PERIPHERAL ORGAN DEFICIENCIES OR FAILURES 审中-公开
标题翻译：基于ARGON的耐气候药物对外围器官缺陷或失败
公开(公告)号：US20130039993A1
公开(公告)日：2013-02-14
申请号：US13576242
申请日：2011-01-21
申请人： Marc Lemaire
发明人： Marc Lemaire
IPC分类号： A61K33/00 , A61P9/00 , C01B23/00 , A61P11/00 , A61P1/16 , A61P13/12
CPC分类号： A61K33/00 , A61K2300/00
摘要： The invention relates to a gaseous composition containing an effective amount of argon gas for use, by inhalation, in preventing or treating a deficiency or failure of at least one peripheral organ in a patient. Preferably, it contains between 15 and 80% by volume of argon, and oxygen, preferably at least 21% by volume of oxygen. The organ deficiency or failure thus treated is transient, preferably from less than one hour to a plurality of days or weeks, or definitive. The organ concerned may be the liver, the kidneys or the lungs.
摘要翻译：本发明涉及含有有效量的氩气的气体组合物，用于通过吸入用于预防或治疗患者中至少一种周围器官的缺陷或衰竭。优选地，其含有15至80体积％的氩气和氧气，优选至少21体积％的氧气。如此治疗的器官缺乏或失败是短暂的，优选从少于1小时到多天或几周或确定。有关器官可能是肝脏，肾脏或肺部。

25. 发明申请

US20120128722A1 Novel Monensin Derivatives for the Treatment and Prevention of Protozoal Infections 有权
标题翻译：用于治疗和预防原生动物感染的新型莫能菌素衍生物
公开(公告)号：US20120128722A1
公开(公告)日：2012-05-24
申请号：US13297367
申请日：2011-11-16
申请人： Jean Delaveau , Emile Vialle , Marc Lemaire , Stephane Pellet-Rostaing , Bruno Andrioletti
发明人： Jean Delaveau , Emile Vialle , Marc Lemaire , Stephane Pellet-Rostaing , Bruno Andrioletti
IPC分类号： A61K31/35 , C07D493/22 , A61K31/366 , A61P33/06 , A61K39/002 , A61P37/04 , A61P33/02 , A61P1/12 , C07D493/10 , A61K31/365
CPC分类号： C07D493/10 , C07D519/00
摘要： This invention relates to novel polyether ionophores, formulations comprising same, and to methods of making and using these compounds and formulations for the treatment and/or prevention of parasitic infection in animals and humans. These compounds exhibit improved safety profiles and/or efficacies as compared to parent compounds.
摘要翻译：本发明涉及新型聚醚离子载体，包含其的制剂，以及制备和使用这些化合物和制剂用于治疗和/或预防动物和人类寄生虫感染的方法。与母体化合物相比，这些化合物表现出改善的安全性和/或功效。

26. 发明申请

US20090252816A1 Inhalable Gaseous Medicament Based On Xenon And Nitrous Oxide 审中-公开
标题翻译：基于氙气和一氧化二氮的可吸入气体药物
公开(公告)号：US20090252816A1
公开(公告)日：2009-10-08
申请号：US12417087
申请日：2009-04-02
申请人： Jacques Abraini , Marc Lemaire
发明人： Jacques Abraini , Marc Lemaire
IPC分类号： A61K33/00
CPC分类号： A61K33/00 , A61K2300/00
摘要： The invention concerns the use of a gaseous mixture containing gas xenon and gas nitrous oxide, and advantageously oxygen, for making all or part of an inhalable medicine for preventing or treating neurointoxication in a human. The xenon/nitrous oxide mixture of the invention acts on one or more cerebral receptors to reduce the release and/or the effects of dopamine, glutamate, serotonin, taurin, GABA, noradrenaline and/or any other neurotransmitter. The proportion by volume of xenon of the mixture ranges between 5 and 45%, and the proportion by volume of nitrous oxide ranges between 10 and 50%, the balance is preferably oxygen.
摘要翻译：本发明涉及使用含有气体氙气和一氧化二氮气体以及有利地为氧气的气体混合物，用于制备用于预防或治疗人类神经毒素的全部或部分可吸入药物。本发明的氙/一氧化二氮混合物作用于一种或多种脑受体，以减少多巴胺，谷氨酸，血清素，牛磺酸，GABA，去甲肾上腺素和/或任何其他神经递质的释放和/或作用。混合物的氙的体积比例为5〜45％，一氧化二氮的体积比为10〜50％，余量优选为氧。

27. 发明申请

US20090026138A1 Process for Separating at Least One Actinide Element From Lanthanide Elements in an Aqueous Medium by Sequestration and Membrane Filtration 失效
标题翻译：通过封存和膜过滤在水介质中从镧系元素分离至少一种锕系元素的方法
公开(公告)号：US20090026138A1
公开(公告)日：2009-01-29
申请号：US12162501
申请日：2007-01-30
申请人： Gilles Bernier , Jean-Marc Adnet , Alain Favre-Reguillon , Jacques Foos , Gerard Le Buzit , Marc Lemaire , Stephane Pellet-Rostaing , Antoine Sorin
发明人： Gilles Bernier , Jean-Marc Adnet , Alain Favre-Reguillon , Jacques Foos , Gerard Le Buzit , Marc Lemaire , Stephane Pellet-Rostaing , Antoine Sorin
IPC分类号： C22B60/02 , G21F9/06 , B01D61/16
CPC分类号： C22B59/00 , B01D61/027 , B01D61/145 , B01D2315/14 , C22B3/205 , G21F9/06 , Y02P10/234
摘要： The invention relates to a process for separating, in an aqueous medium, at least one actinide element from one or more lanthanide elements by using at least one molecule which sequesters the said actinide element to be separated and membrane filtration, the said process successively comprising: a) a step of bringing at least one molecule which sequesters the said actinide element in contact with the aqueous medium, the said molecule not being retained in the non-complexed state by the said membrane and being capable of forming a complex with the actinide element to be separated, comprising the said element and at least two of the said sequestering molecules, which complex is capable of being retained by the membrane; b) a step of passing the aqueous medium over the membrane in order to form a permeate on one side, comprising an aqueous effluent depleted of the said actinide element, and a retentate comprising the said complex.
摘要翻译：本发明涉及通过使用至少一种螯合所述待分离的锕系元素和膜过滤的分子在水性介质中从至少一种镧系元素分离至少一种锕系元素的方法，所述方法依次包括： a）使至少一个螯合所述锕系元素与水介质接触的分子的步骤，所述分子不被所述膜保持在非络合状态，并且能够与锕系元素形成络合物被分离，其包含所述元素和至少两个所述螯合分子，所述复合物能够被膜保留; b）使含水介质通过膜以在一侧上形成渗透物的步骤，其包含贫化所述锕系元素的水性流出物和包含所述络合物的渗余物。

28. 发明申请

US20050180926A1 Inhalable aerosol medicament for the treatment or prevention of pain 审中-公开
标题翻译：用于治疗或预防疼痛的可吸入气雾剂
公开(公告)号：US20050180926A1
公开(公告)日：2005-08-18
申请号：US11107809
申请日：2005-04-18
申请人： Laurent Lecourt , Franck Lescure , Marc Lemaire
发明人： Laurent Lecourt , Franck Lescure , Marc Lemaire
IPC分类号： A61K9/00 , A61K9/10 , A61K9/12 , A61K9/72 , A61K31/167 , A61K31/192 , A61K31/4355 , A61K31/573 , A61K31/616 , A61K33/00 , A61K45/06 , A61M11/00 , A61P23/00 , A61P29/00 , A61L9/04 , A61K9/14 , A61K31/60
CPC分类号： A61K9/008 , A61K9/0073 , A61K9/124 , A61K33/00 , A61K45/06 , A61K2300/00
摘要： The invention concerns the use of at least one gas in combination with at least one active product for manufacturing an inhalable medicament or part of an inhalable medicament intended for the treatment or prevention of pain in humans or animals. The gas is chosen from among helim, oxygen, nitrogen, xenon, hydrogen, carbon monoxide (CO), carbon dioxide (CO2), argon, krypton, nitrogen monoxide (NO), nitrogen protoxide (N2O), carbonated hydrocarbons, fluorocarbons and mixtures of several of these gases. The active product is chosen from among paracetamol, acetylsalicylic acid, arylcarboxylic acid, corticosteroids, mineralosteroids, non-steoroidal anti-inflammatory drugs and their derivatives, codeine and its derivatives, morphine and morphine mimetics.
摘要翻译：本发明涉及至少一种气体与至少一种活性产品的组合用于制造用于治疗或预防人或动物疼痛的可吸入药物或可吸入药物的一部分。气体选自直升机，氧气，氮气，氙气，氢气，一氧化碳（CO），二氧化碳（CO 2/2），氩气，氪气，一氧化氮（NO），氮氧化氮（N O 2），碳酸烃，碳氟化合物和这些气体中的几种的混合物。活性产物选自对乙酰氨基酚，乙酰水杨酸，芳基羧酸，皮质类固醇，类固醇，非甾体抗炎药及其衍生物，可待因及其衍生物，吗啡和吗啡模拟物。

29. 发明授权

US5344624A Method for recovering with the aid of a crown compound plutonium (IV) present in solutions, such as aqueous effluents, concentrated solutions of fission products and concentrated solutions of plutonium 失效
标题翻译：借助于存在于溶液中的冠化合物钚（IV），如含水废水，裂变产物浓缩溶液和钚浓缩溶液回收的方法
公开(公告)号：US5344624A
公开(公告)日：1994-09-06
申请号：US935038
申请日：1992-08-25
申请人： Jacques Foos , Marc Lemaire , Alain Guy , Vincent Guyon , Rodolphe Chomel , Andre Delo Ge , Pierre Doutreluigne , Henri Le Roy
发明人： Jacques Foos , Marc Lemaire , Alain Guy , Vincent Guyon , Rodolphe Chomel , Andre Delo Ge , Pierre Doutreluigne , Henri Le Roy
IPC分类号： G21C19/46 , G21F9/06 , C22B60/04 , B01D11/00
CPC分类号： G21C19/46 , G21F9/06 , Y02W30/883
摘要： The invention concerns the recovery of Pu (IV) by using crown compounds.According to the invention, the aqueous solution containing the plutonium (IV) is placed in contact with at least one crown compound, for example DCH 18C6, dissolved in an organic diluting agent, such as benzonitrile. In the case where the solution only contains traces of Pu, it is possible to use a crown compound secured to a solid phase, such as silica.The aqueous solution is a concentrated solution of fission products, an effluent originating from an irradiated nuclear fuel reprocessing installation or a concentrated solution of plutonium with americium.
摘要翻译：本发明涉及通过使用冠状化合物回收Pu（IV）。根据本发明，含有钚（IV）的水溶液与至少一种溶解在有机稀释剂如苄腈中的冠状化合物（例如DCH 18C6）接触。在溶液仅含有痕量Pu的情况下，可以使用固定在固相上的冠状化合物，例如二氧化硅。水溶液是裂变产物的浓缩溶液，源自辐照的核燃料后处理装置的流出液或钚与钚的浓缩溶液。

30. 发明授权

US5268448A Conducting polymers derived from fluorinated thiophenes 失效
标题翻译：衍生自氟化噻吩的聚合物的导电
公开(公告)号：US5268448A
公开(公告)日：1993-12-07
申请号：US899130
申请日：1992-06-16
申请人： Werner Buechner , Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
发明人： Werner Buechner , Marc Lemaire , Jean Roncali , Robert Garreau , Francis Garnier , Etienne Hannecart
IPC分类号： C07D333/12 , C08G61/12 , H01B1/12 , H01M4/60 , C08G75/00
CPC分类号： C08G61/126 , C07D333/12 , H01B1/127 , H01M4/60
摘要： Substituted thiophenes of general formula: ##STR1## in which: R represents hydrogen atom or an aliphatic group containing from 1 to 4 carbon atoms,X and Z may be identical or different and represent a hydrogen atom or a fluorine atom,Y represents an at least partially fluorinated aliphatic or aromatic group,m represents an integer equal to or greater than 1, andn represents an integer such that 0.ltoreq.n.ltoreq.12.The invention also relates to the electrically conducting polymers containing recurring units derived from monomers chosen from the substituted thiophenes.
摘要翻译：具有以下通式的取代的噻吩：其中：R表示氢原子或含有1至4个碳原子的脂族基团，X和Z可以相同或不同，表示氢原子或氟原子，Y表示最少部分氟化的脂族或芳族基团，m表示等于或大于1的整数，n表示0≤n≤12的整数。本发明还涉及含有衍生自选自取代的噻吩的单体的重复单元的导电聚合物。

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