专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

WO2015071647A2 METHOD OF ISOLATING IONS 审中-公开
标题翻译：分离离子的方法
公开(公告)号：WO2015071647A2
公开(公告)日：2015-05-21
申请号：PCT/GB2014/053333
申请日：2014-11-11
申请人： MICROMASS UK LIMITED
发明人： HOYES, John Brian , PRINGLE, Steven Derek , SALARZAEI, Farnoush , WILDGOOSE, Jason Lee
CPC分类号： G01N27/622 , H01J49/0031 , H01J49/40 , H01J49/4215
摘要： A method of mass spectrometry is disclosed comprising isolating a group of different ions derived from chemical compounds in the same class (12,13), wherein the different ions have different mass to charge ratios and ion mobilities. The step of isolating comprises temporally separating the ions according to their ion mobility in an ion mobility separator; and mass filtering the ions according to mass to charge ratio with a mass filter. The mass to charge ratios transmitted by the mass filter are varied as a function of time such that said different ions derived from chemical compounds in the same class (12,13) are transmitted by the mass filter and other ions are not transmitted by the mass filter.
摘要翻译：公开了一种质谱方法，其包括分离衍生自同一类别（12,13）中的化合物的一组不同离子，其中不同的离子具有不同的质荷比和离子迁移率。分离步骤包括在离子迁移分离器中根据其离子迁移率暂时分离离子; 并根据质量与质量过滤器的质荷比质量过滤离子。通过质量过滤器传输的质荷比随着时间的变化而变化，使得衍生自相同等级（12,13）中的化合物的所述不同离子通过质量过滤器传输，而其他离子不被质量传递过滤。

22. 发明申请

WO2015004457A1 INTELLIGENT DYNAMIC RANGE ENHANCEMENT 审中-公开
标题翻译：智能动态范围增强
公开(公告)号：WO2015004457A1
公开(公告)日：2015-01-15
申请号：PCT/GB2014/052093
申请日：2014-07-09
申请人： MICROMASS UK LIMITED
发明人： GREEN, Martin Raymond , PRINGLE, Steven Derek , WILDGOOSE, Jason Lee
IPC分类号： H01J49/00 , H01J49/02
CPC分类号： H01J49/061 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/10 , H01J49/40
摘要： A method of mass spectrometry is disclosed comprising transmitting ions and obtaining first mass spectral data and automatically determining during an acquisition whether the first mass spectral data suffers from saturation or is approaching saturation. If a determination is made during an acquisition that the first mass spectral data suffers from saturation or is approaching saturation then the method further comprises automatically changing or altering the intensity of ions which are detected by an ion detector and obtaining second mass spectral data. The method further comprises substituting one or more portions of the first mass spectral data with one or more corresponding portions of the second mass spectral data multiplied or scaled by an attenuation or scale factor and/or by an integer or other value so as to form a composite mass spectrum, wherein the composite mass spectrum comprises one or more ion peaks from the first mass spectral data and one or more ion peaks from the second mass spectral data.
摘要翻译：公开了一种质谱法，其包括传输离子并获得第一质谱数据，并在获取期间自动确定第一质谱数据是饱和还是接近饱和。如果在采集期间确定第一质谱数据饱和或正在接近饱和，则该方法还包括自动改变或改变由离子检测器检测的离子的强度并获得第二质谱数据。该方法还包括用第二质谱数据的一个或多个对应部分替换第一质谱数据的一个或多个部分，该第二质谱数据与衰减或比例因子相乘或缩放，以及/或整数或其它值，以便形成复合质谱，其中所述复合质谱包括来自所述第一质谱数据的一个或多个离子峰和来自所述第二质谱数据的一个或多个离子峰。

23. 发明申请

WO2014140542A1 A DDA EXPERIMENT WITH REDUCED DATA PROCESSING 审中-公开
标题翻译：具有减少数据处理的DDA实验
公开(公告)号：WO2014140542A1
公开(公告)日：2014-09-18
申请号：PCT/GB2014/050697
申请日：2014-03-10
申请人： MICROMASS UK LIMITED
发明人： BROWN, Jeffery Mark , GILES, Kevin , GREEN, Martin Raymond , HOYES, John Brian , JONES, Christopher , MORRIS, Michael Raymond , PRINGLE, Steven Derek , RICHARDSON, Keith , SALARZAEI, Farnoush , WILDGOOSE, Jason Lee
IPC分类号： H01J49/00 , G01N27/62
CPC分类号： H01J49/005 , G01N27/622 , H01J49/0031 , H01J49/0045 , H01J49/0072
摘要： A method of mass spectrometry is disclosed comprising: performing a survey scan of a plurality of different types of parent or precursor ions, wherein said survey scan comprises analysing the ion mobilities of the ions and mass analysing the ions; determining the charge states of parent or precursor ions analysed in the survey scan based on their determined combinations of ion mobility and mass to charge ratio; selecting a parent or precursor ion for fragmentation or reaction; and fragmenting or reacting said selected ion, wherein the fragmentation or reaction conditions are selected from a plurality of different fragmentation or reaction conditions based upon the determined charge state of the selected ion.
摘要翻译：公开了一种质谱方法，包括：对多种不同类型的母体或前体离子进行测量扫描，其中所述测量扫描包括分析离子的离子迁移率和大量分析离子; 基于它们确定的离子迁移率和质荷比的组合来确定在测量扫描中分析的亲本或前体离子的电荷状态; 选择母体或前体离子进行碎裂或反应; 并且使所述选择的离子断裂或反应，其中基于所选离子的确定的电荷状态，所述断裂或反应条件选自多个不同的断裂或反应条件。

24. 发明申请

WO2013171493A2 METHOD OF MS/MS MASS SPECTROMETRY 审中-公开
标题翻译： MS / MS质谱法的方法
公开(公告)号：WO2013171493A2
公开(公告)日：2013-11-21
申请号：PCT/GB2013/051259
申请日：2013-05-16
申请人： MICROMASS UK LIMITED
发明人： BROWN, Jeffery Mark , GREEN, Martin Raymond , PRINGLE, Steven Derek
IPC分类号： H01J49/00
CPC分类号： H01J49/0054 , H01J49/0031 , H01J49/0072
摘要： A method of mass spectrometry is disclosed comprising alternating between a first mode in which parent ions are mass analysed and a second mode in which the parent ions are subjected to Electron Capture Dissociation ("ECD") at atmospheric pressure so as to produce fragment ions which are then mass analysed. The parent ions are associated with their fragment ions based on the times at which they were detected. This method enables parent ions to be associated with their fragment ions, even when the ECD fragmentation is performed at atmospheric pressure.
摘要翻译：公开了一种质谱法，其包括在母体离子质量分析的第一模式和母体离子在大气压下进行电子俘获解离（“ECD”）的第二模式之间交替，以产生碎片离子，其中然后进行质量分析。基于它们被检测的时间，母体离子与它们的碎片离子相关联。这种方法使得母体离子与其碎片离子相关联，即使当在大气压下进行ECD断裂时。

25. 发明申请

WO2018115894A1 UTILISING FRAGMENTATION IN ANALYSIS OF LIPIDS AND OTHER COMPOUND CLASSES 审中-公开
公开(公告)号：WO2018115894A1
公开(公告)日：2018-06-28
申请号：PCT/GB2017/053871
申请日：2017-12-21
申请人： MICROMASS UK LIMITED
发明人： RICHARDSON, Keith George , PRINGLE, Steven Derek
IPC分类号： H01J49/00 , G01N27/62
摘要： A method of mass and/or ion mobility spectrometry is disclosed that comprises ionising analyte from a sample so as to generate a plurality of ions, separating precursor ions from first fragment and/or other ions of the plurality of ions, fragmenting or reacting at least some of the precursor ions using a fragmentation, reaction or collision device so as to generate second fragment ions, and then analysing at least some ions that emerge from the fragmentation, reaction or collision device. The sample is classified and/or identified based on the analysis of the second fragment ions.

26. 发明申请

WO2017208030A1 MASS SPECTROMETRY IMAGING 审中-公开
标题翻译：质谱法成像
公开(公告)号：WO2017208030A1
公开(公告)日：2017-12-07
申请号：PCT/GB2017/051616
申请日：2017-06-05
申请人： MICROMASS UK LIMITED
发明人： PRINGLE, Steven Derek , JONES, Emrys , O'BRIEN, Stephen , HESSE, Anthony , MORRIS, Mike , TAKATS, Zoltan
IPC分类号： H01J49/14 , H01J49/16
摘要： There is provided an apparatus comprising a first ion source (10) arranged and adapted to emit a spray of charged droplets (11), and a control system arranged and adapted to control one or more spatial properties of said spray of charged droplets (11) in use by automatically varying or adjusting one or more parameters of said first ion source.
摘要翻译：提供了一种装置，其包括布置并且适于发射带电液滴（11）的喷雾的第一离子源（10），以及布置并且适于控制一个或多个空间特性的装置通过自动改变或调节所述第一离子源的一个或多个参数来使用带电液滴（11）的所述喷雾。

27. 发明申请

WO2017098255A1 FEEDBACK APPARATUS 审中-公开
标题翻译：反馈设备
公开(公告)号：WO2017098255A1
公开(公告)日：2017-06-15
申请号：PCT/GB2016/053880
申请日：2016-12-09
申请人： MICROMASS UK LIMITED
发明人： THRELFALL, Richard , RICHARDSON, Keith George , PRINGLE, Steven Derek , MORRIS, Michael Raymond
IPC分类号： A61B10/02 , G01N1/02 , H01J49/04 , G01N1/04 , G01N1/28 , A61B17/00 , A61B90/00 , A61B18/00 , A61B17/32 , A61B18/14 , A61B18/20
CPC分类号： A61B10/02 , A61B17/320068 , A61B18/14 , A61B18/1402 , A61B2017/00022 , A61B2017/00115 , A61B2017/00221 , A61B2018/00297 , A61B2090/366 , A61B2218/008 , G01N2001/028 , G01N2001/045 , G01N2001/2886 , G01N2035/00881
摘要： A feedback apparatus (22) is provided for use with a system (10) that comprises an analyser (16) and a sampling device (12). The feedback apparatus (22) comprises a receiver (20) that receives from the analyser 16 information relating to a sample obtained using the sampling device (12). The feedback apparatus (22) comprises a feedback device that provides an indication based on the information to an operator (14) of the sampling device (2) whilst the sampling device (12) is within the operator's visual field.
摘要翻译：反馈装置（22）被提供用于包括分析器（16）和采样装置（12）的系统（10）。反馈装置（22）包括从分析器16接收与使用采样装置（12）获得的样本有关的信息的接收器（20）。反馈装置（22）包括反馈装置，该反馈装置在采样装置（12）位于操作者的视野内的同时向采样装置（2）的操作员（14）提供基于该信息的指示。

28. 发明申请

WO2016142692A1 SPECTROMETRIC ANALYSIS 审中-公开
标题翻译：光谱分析
公开(公告)号：WO2016142692A1
公开(公告)日：2016-09-15
申请号：PCT/GB2016/050622
申请日：2016-03-07
申请人： MICROMASS UK LIMITED
发明人： RICHARDSON, Keith , PRINGLE, Steven Derek , BALOG, Júlia , TAKÁTS, Zoltán
IPC分类号： A61B10/02 , G01N1/02 , H01J49/00 , G01N33/68 , A61B17/00 , G01N3/00 , G01N9/00
CPC分类号： H01J49/049 , A61B1/00013 , A61B1/041 , A61B1/31 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B5/14542 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2218/008 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/48735 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/18 , G06F19/324 , G06F19/3481 , G16H50/20 , H01J49/0004 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0422 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26
摘要： A method of spectrometric analysis comprises obtaining one or more sample spectra for an aerosol, smoke or vapour sample. The one or more sample spectra are subjected to pre-processing and then multivariate and/or library based analysis so as to classify the aerosol, smoke or vapour sample. The results of the analysis are used for various surgical or non-surgical applications.
摘要翻译：光谱分析的方法包括获得气溶胶，烟雾或蒸气样品的一个或多个样品光谱。对一个或多个样品光谱进行预处理，然后进行多变量和/或基于文库的分析，以便对气溶胶，烟雾或蒸汽样品进行分类。分析结果用于各种手术或非手术应用。

29. 发明申请

WO2016142691A1 RAPID EVAPORATIVE IONISATION MASS SPECTROMETRY ("REIMS") AND DESORPTION ELECTROSPRAY IONISATION MASS SPECTROMETRY ("DESI-MS") ANALYSIS OF SWABS AND BIOPSY SAMPLES 审中-公开
标题翻译：快速离子发光质谱（“REIMS”）和解吸电沉积物质谱（“DESI-MS”）SWABS和生物样品分析
公开(公告)号：WO2016142691A1
公开(公告)日：2016-09-15
申请号：PCT/GB2016/050621
申请日：2016-03-07
申请人： MICROMASS UK LIMITED
发明人： TAKÁTS, Zoltán , JONES, Emrys , LANGRIDGE, James Ian , MORRIS, Michael Raymond , KARANCSI, Tamás , PRINGLE, Steven Derek , BALOG, Júlia , SIMON, Dániel , GÖDÖRHÁZY, Lajos , SZALAY, Dániel , RICHARDSON, Keith
IPC分类号： G01N33/68
CPC分类号： H01J49/049 , A61B1/00013 , A61B1/041 , A61B1/31 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B5/14542 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61B2010/0083 , A61B2017/320069 , A61B2018/00577 , A61B2218/008 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/622 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/48735 , G01N33/6848 , G01N33/6851 , G01N33/92 , G01N2001/2223 , G01N2333/195 , G01N2405/00 , G01N2405/04 , G01N2405/08 , G01N2570/00 , G01N2800/26 , G06F19/18 , G06F19/324 , G06F19/3481 , G16H50/20 , H01J49/0004 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0422 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26
摘要： A method is disclosed comprising providing a biological sample on a swab (900), directing a spray of charged droplets onto a surface of the swab (900) in order to generate a plurality of analyte ions, and analysing the analyte ions.
摘要翻译：公开了一种方法，其包括在拭子（900）上提供生物样品，将带电液滴的喷雾引导到拭子（900）的表面上，以便产生多个分析物离子并分析分析物离子。

30. 发明申请

WO2015189545A1 ION MOBILITY SPECTROMETRY DATA DIRECTED ACQUISITION 审中-公开
标题翻译：离子移动光谱数据指导采集
公开(公告)号：WO2015189545A1
公开(公告)日：2015-12-17
申请号：PCT/GB2015/000173
申请日：2015-06-11
申请人： MICROMASS UK LIMITED
发明人： GILES, Kevin , GREEN, Martin Raymond , PRINGLE, Steven Derek , RICHARDSON, Keith , WILDGOOSE, Jason Lee
IPC分类号： H01J49/00 , G01N27/62
CPC分类号： H01J49/0031 , G01N27/622 , H01J49/0045
摘要： A method of analysing ions, comprising performing an initial multidimensional survey scan comprising separating parent ions according to a first physico-chemical property and separating said parent ions according to a second physico-chemical property, producing a two-dimensional data set comprising data corresponding to said first physico- chemical property and data corresponding to said second physico-chemical property, identifying one or more target ion species of interest and determining a mode of operation of a mass spectrometer for said target ion species of interest using data relating to said target ion species of interest in said two-dimensional data set, wherein said mode of operation comprises the location of fragmentation of said target ions of interest.
摘要翻译：一种分析离子的方法，包括执行初始多维测量扫描，其包括根据第一物理化学性质分离亲本离子并根据第二物理化学性质分离所述亲本离子，产生二维数据集，其包括对应于所述第一物理化学性质和对应于所述第二物理化学性质的数据，识别感兴趣的一种或多种靶离子物种，并使用与所述目标离子相关的数据确定所述目标离子物种的质谱仪的操作模式所述二维数据集中的感兴趣物种，其中所述操作模式包括感兴趣的所述目标离子的碎裂位置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式