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21. 发明公开

EP2658916A4 THERMOPLASTIC COMPOSITIONS FOR SHEET MATERIALS HAVING IMPROVED TENSILE PROPERTIES 审中-公开
标题翻译：热塑性组合与改进的拉伸铁路类材料
公开(公告)号：EP2658916A4
公开(公告)日：2014-07-23
申请号：EP11854001
申请日：2011-12-08
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F , NG WING-CHAK , MACDONALD JOHN GAVIN
IPC分类号： C08L23/00 , C08J5/18 , C08K3/00 , C08K7/00 , D01F6/04
CPC分类号： C08L23/10 , B82Y30/00 , C08L2205/02

22. 发明专利

AU2012222971B2 Transdermal patch containing microneedles 未知
公开(公告)号：AU2012222971B2
公开(公告)日：2016-01-21
申请号：AU2012222971
申请日：2012-01-16
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F
IPC分类号： A61M37/00 , A61M35/00
摘要： A transdermal patch that can easily deliver a controlled volume of a fluidic drug compound to the skin is provided. More particularly, the patch contains a microneedle assembly that is configured to be placed in fluid communication with a drug delivery assembly. The microneedle assembly contains a support and a plurality of microneedles that extend outwardly from the support. The microneedles are formed with one or more channels of a certain dimension such that passive capillary flow drives the flow of the drug compound. The drug delivery system contains a reservoir for the drug compound that is in fluid communication with -a rate control membrane that helps control the flow rate of the drug compound by modulating its pressure downstream from the reservoir. A release member is also positioned adjacent to the microneedle and drug delivery assemblies. Prior to use, the release member acts as a barrier to the flow of the drug compound and thus inhibits premature leakage. In this manner, the patch can initially be provided in an "inactive" configuration in which the drug compound is securely retained. When it is desired to release the drug compound, the patch can simply be activated by at least partially separating the release member from the drug delivery and microneedle assemblies.

23. 发明专利

CA2945502A1 DRAPED MICRONEEDLE ARRAY 未知
公开(公告)号：CA2945502A1
公开(公告)日：2015-11-25
申请号：CA2945502
申请日：2015-04-29
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW T , GADSBY ELIZABETH DEIBLER , ROSS RUSSELL F
IPC分类号： A61M37/00
摘要： The configuration of an elongate aperture in a membrane draped over a microneedle assembly may be controlled by controlling the manner in which the aperture is formed and/or by controlling the manner in which the membrane is draped. At least a portion of the membrane may be spaced apart from a microneedle so that a gap is defined between the membrane and the microneedle. The gap may be configured for at least partially controlling the formation of the elongate aperture. The shape of the gap may optionally be at least partially defined by a pleat in the membrane. Any pleats may be aligned in a predetermined manner. The elongate aperture may be formed by a piercing member that is passed through a hole in the microneedle assembly prior to piercing the membrane. The piercing member may be a laser beam.

24. 发明专利

CA2945007A1 CARTRIDGE PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS 未知
公开(公告)号：CA2945007A1
公开(公告)日：2015-11-05
申请号：CA2945007
申请日：2015-04-29
申请人： KIMBERLY CLARK CO
发明人： BAKER ANDREW T , GADSBY ELIZABETH DEIBLER , ROSS RUSSELL F , HAGAN LUKE
IPC分类号： A61M37/00
摘要： A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus. The body may also at least partially define first and second openings to the interior of the body, wherein the first and second openings are respectively proximate opposite first and second ends of the body. The cartridge may also include a self-sealing member at least partially closing the first opening, and a movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body.

25. 发明专利

AU2010329568B2 Transdermal delivery device 未知
公开(公告)号：AU2010329568B2
公开(公告)日：2015-06-11
申请号：AU2010329568
申请日：2010-11-09
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F
IPC分类号： A61M5/158 , A61M37/00
摘要： The present invention relates generally to a transdermal delivery device which is suitable for the transdermal delivery or removal of substances, and in particular relates to a transdermal delivery device having a support and a plurality of microneedles projecting outwardly from the support, at least one microneedle including a channel positioned on the exterior surface which aligns with at least one aperture being formed in the support.

26. 发明专利

AU2010209325B2 Absorbent articles containing a multifunctional gel 未知
公开(公告)号：AU2010209325B2
公开(公告)日：2015-05-28
申请号：AU2010209325
申请日：2010-01-29
申请人： KIMBERLY CLARK CO
发明人： YAHIAOUI ALI , KRAUTKRAMER CANDACE DYAN , LATIMER MARGARET G , LINTON JACK NELSON , ROSS RUSSELL F , DENNIS MELISSA JEAN , WOLTMAN GARRY ROLAND
IPC分类号： A61F13/511 , A61F13/53 , A61F13/58 , A61L15/60
摘要： Improved skin-adhesive compositions for bonding a substrate, such as an absorbent article, to skin are disclosed. More particularly, the skin-adhesive composition has an improved, yet gentle, adhesion to the skin of a user, while maintaining strong, effective bonding to various inanimate, non-skin substrates. In one embodiment, the skin- adhesive composition can provide one or more skin benefit agents to the user. The skin-adhesive composition may be applied to an absorbent article, such as a panty-liner, sanitary napkin, or an incontinence article, for directly adhering the article to the skin of a user.

27. 发明专利

CA2901568A1 TRANSDERMAL DRUG DELIVERY DEVICE 未知
公开(公告)号：CA2901568A1
公开(公告)日：2014-09-04
申请号：CA2901568
申请日：2014-02-28
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F , HAGAN LUKE , MALKIN ALEX , HATCHETT DEREK , MARKS JACOB , LUTZOW THOMAS
IPC分类号： A61M37/00
摘要： A transdermal drug delivery device is disclosed that may comprise a housing including an upper housing portion and a lower housing portion. The lower housing portion may define a bottom surface including skin attachment means for releaseably attaching the lower housing portion to skin of a user. The upper housing portion may at least partially surround a central region of the device. The device may also include a microneedle assembly and a reservoir disposed within the central region. The reservoir may be in fluid communication with the microneedle assembly. Additionally, the device may include a pushing element disposed above the microneedle assembly within the central region. The pushing element may be configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly and an upward component transmitted through the skin attachment means.

28. 发明专利

MX2013007280A COMPOSICIONES TERMOPLASTICAS PARA MATERIALES DE HOJA QUE TIENEN PROPIEDADES DE TENSION MEJORADAS. 未知
公开(公告)号：MX2013007280A
公开(公告)日：2013-09-06
申请号：MX2013007280
申请日：2011-12-08
申请人： KIMBERLY CLARK CO
发明人： NG WING-CHAK , MACDONALD JOHN GAVIN , ROSS RUSSELL F
IPC分类号： C08L23/00 , C08J5/18 , C08K3/00 , C08K7/00 , D01F6/04
摘要： Está descrita una composición termoplástica adecuada para formar materiales de hoja con propiedades de tensión mejoradas. La composición termoplástica incluye de desde alrededor de 1 por ciento por peso a alrededor de 98 por ciento por peso de un polímero formador de película formador de fibra, de desde alrededor de 1 a alrededor de 98 por ciento por peso de un polímero de tasa de flujo de derretido teniendo una tasa de flujo de derretido de 20 gramos por 10 minutos y de desde alrededor de 0.1 a alrededor de 10 por ciento por peso de nanopartículas. Las nanopartículas pueden ser nanopartículas cilíndricas teniendo una proporción de aspecto promedio mayor de alrededor de 1 menor de alrededor de 500.

29. 发明专利

AU2003256684A1 METHOD FOR ENHANCING THE SOFTNESS OF PAPER-BASED PRODUCTS 未知
公开(公告)号：AU2003256684A1
公开(公告)日：2004-06-03
申请号：AU2003256684
申请日：2003-07-24
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F , LAU JARK
IPC分类号： D21H21/22 , D21H25/04
摘要： A method for softening a paper-based product, such as facial tissues, bath tissues, paper towels, etc., is provided. In particular, the method of the present invention includes exposing a cellulosic fibrous material to ionizing radiation (e.g., electron beam radiation). It is believed that the ionizing radiation induces vibrational forces throughout the cellulosic fibrous structure, thereby disrupting hydrogen bonds between adjacent fibers and opening the crystalline structure of the material to result in a softer product.

30. 发明专利

CA2853214C TRANSDERMAL DELIVERY OF HIGH VISCOSITY BIOACTIVE AGENTS 未知
公开(公告)号：CA2853214C
公开(公告)日：2020-03-24
申请号：CA2853214
申请日：2012-10-16
申请人： KIMBERLY CLARK CO
发明人： ROSS RUSSELL F
IPC分类号： A61M37/00 , A61M5/158
摘要： A device and method for delivering a high viscosity composition is described. The composition includes a bioactive agent for delivery to a subject in need thereof. The method delivers the bioactive agent at a high bioavailability and with little loss of agent to the natural defense mechanisms of the body. The device includes one or more microneedles with structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes.

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