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21. 发明申请

US20100137905A1 IMPLANT SYSTEMS AND METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA 有权
标题翻译：植入系统和治疗阻塞性睡眠障碍的方法
公开(公告)号：US20100137905A1
公开(公告)日：2010-06-03
申请号：US12578271
申请日：2009-10-13
申请人： Kevin S. Weadock , Robert A. Rousseau , John R. Jaccobs
发明人： Kevin S. Weadock , Robert A. Rousseau , John R. Jaccobs
IPC分类号： A61B17/03
CPC分类号： A61F5/56 , A61B2017/00557 , A61B2017/0404 , A61B2017/0417 , A61B2017/06176 , A61F2/00 , A61F2/0063 , A61F5/566
摘要： A system, method and kit for treating obstructive sleep apnea. The system includes a first implant adapted for implantation in an inframandibular region and having at least one aperture therethrough, and a ribbon-like element having first and second ends and a substantially uniform, non-circular cross section along its length. The ribbon-like element is adapted for implantation in a tongue with the first and second ends extending through the at least one aperture in the first implant for coupling the ribbon-like element with the first implant.
摘要翻译：一种用于治疗阻塞性睡眠呼吸暂停的系统，方法和试剂盒。该系统包括适于植入在下颌下区域并且具有穿过其中的至少一个孔的第一植入物，以及具有沿其长度的第一端和第二端以及基本均匀的非圆形截面的带状元件。带状元件适于植入舌头中，第一和第二端延伸穿过第一植入物中的至少一个孔，用于将带状元件与第一植入物联接。

22. 发明申请

US20100037901A1 Methods and devices for treatment of obstructive sleep apnea 有权
标题翻译：治疗阻塞性睡眠呼吸暂停的方法和装置
公开(公告)号：US20100037901A1
公开(公告)日：2010-02-18
申请号：US12228681
申请日：2008-08-14
申请人： Robert A. Rousseau , Kevin S. Weadock
发明人： Robert A. Rousseau , Kevin S. Weadock
IPC分类号： A61F5/56 , A61F2/02
CPC分类号： A61F5/56 , A61F5/566
摘要： A pharyngeal retractor device and implantation methods are provided for use in the treatment of obstructive sleep apnea. The device includes a retracting element and a tissue engaging element that promotes tissue ingrowth around or onto the retracting element. The device is implanted in tissue space beneath the pharyngeal wall to alter the shape of the wall. The device may be implanted through the oral cavity alone or by using a trocar or a hand-held delivery system to deliver the device through the pharyngeal wall. Alternatively, the device may be implanted using an open, direct visualization approach from the side of a patient's neck.
摘要翻译：提供咽收缩器装置和植入方法用于治疗阻塞性睡眠呼吸暂停。该装置包括回缩元件和组织接合元件，其促进组织向内生长在收缩元件周围或上。该装置植入咽壁下方的组织空间以改变壁的形状。该装置可以单独地通过口腔植入，或者通过使用套管针或手持递送系统将装置输送通过咽壁。或者，可以使用来自患者颈部侧面的开放的直接可视化方法来植入该装置。

23. 发明授权

US06808518B2 Methods and devices for treating diseased blood vessels 有权
标题翻译：用于治疗患病血管的方法和装置
公开(公告)号：US06808518B2
公开(公告)日：2004-10-26
申请号：US09965949
申请日：2001-09-28
申请人： Parris S. Wellman , Kevin S. Weadock
发明人： Parris S. Wellman , Kevin S. Weadock
IPC分类号： A61M3100
CPC分类号： A61M37/0015 , A61M25/1011 , A61M29/02 , A61M37/00 , A61M2025/105 , A61M2025/1052 , A61M2025/1086 , A61M2037/003
摘要： The present invention provides a mechanism by which the physical properties of diseased blood vessel walls can be manipulated to achieve an effective vessel lumen diameter for a prolonged period of time. The methods and devices of the present invention selectively isolate and treat the medial or adventitial layers of these diseased blood vessels. The invention is based on the delivery of proteolytic enzymes and crosslinking agents via specialized delivery devices to a select layer of the diseased blood vessel wall. By isolating and treating these layers of the artery, collagen degrading and collagen crosslinking agents can be delivered so as to affect the diameter of the blood vessels and control blood flow therein.
摘要翻译：本发明提供了一种机制，通过该机制可以操纵患病血管壁的物理性能以在更长的时间内实现有效的血管腔直径。本发明的方法和装置选择性地分离和治疗这些患病血管的内侧或外膜层。本发明基于通过专门的递送装置将蛋白水解酶和交联剂递送到患病血管壁的选择层。通过分离和处理这些动脉层，可以递送胶原蛋白降解和胶原交联剂，以便影响血管的直径并控制其中的血流。

24. 发明授权

US08894683B2 Device for attaching, relocating and reinforcing tissue and methods of using same 有权
标题翻译：用于附着，重新定位和加强组织的装置及其使用方法
公开(公告)号：US08894683B2
公开(公告)日：2014-11-25
申请号：US12151235
申请日：2008-05-05
申请人： Kevin S. Weadock , Parris Wellman , Martin Weisberg , Philip Prentice , Earl Adamy
发明人： Kevin S. Weadock , Parris Wellman , Martin Weisberg , Philip Prentice , Earl Adamy
IPC分类号： A61B17/08 , A61B17/00 , A61B17/04 , A61F2/00
CPC分类号： A61B17/0401 , A61B2017/00004 , A61B2017/00743 , A61B2017/00778 , A61B2017/00805 , A61B2017/0412 , A61B2017/0427 , A61B2017/0454 , A61B2017/0458 , A61B2017/0462 , A61B2017/0464 , A61F2/0045
摘要： A device for attaching, relocating or reinforcing tissue includes a first tissue anchoring portion having a support plate and a plurality of barbs extending from the support plate for engaging tissue at a first location, a second tissue anchoring portion having a support plate and a plurality of barbs extending from the support plate for engaging tissue at a second location which is different from the first location, and a connection element, such as a suture or a mesh structure, interposed between and interconnecting the first tissue anchoring portion and the second tissue anchoring portion. The support plate of at least one of the first tissue anchoring portion and the second tissue anchoring portion may have longitudinally axially formed therethrough a bore for receiving the connecting element so that the surgeon may pull on the end of the connecting element to adjust the distance between the first tissue anchoring portion and the second tissue anchoring portion.
摘要翻译：用于附接，重新定位或加强组织的装置包括具有支撑板的第一组织锚固部分和从支撑板延伸的多个倒钩，用于在第一位置处接合组织，第二组织锚定部分具有支撑板和多个从支撑板延伸的倒钩，用于在不同于第一位置的第二位置处接合组织;以及连接元件，例如缝合线或网状结构，插入在第一组织锚固部分和第二组织锚定部分之间并将其互连。第一组织锚固部分和第二组织锚固部分中的至少一个的支撑板可以纵向轴向地形成在其中，用于接收连接元件的孔，使得外科医生可以在连接元件的端部上拉动以调节第一组织锚定部分和第二组织锚定部分。

25. 发明申请

US20070156161A1 Method and device for repositioning tissue 审中-公开
标题翻译：用于重新定位组织的方法和装置
公开(公告)号：US20070156161A1
公开(公告)日：2007-07-05
申请号：US11322144
申请日：2005-12-29
申请人： Kevin S. Weadock , Parris Wellman , James J. Rudnick , Jessica Liberatore
发明人： Kevin S. Weadock , Parris Wellman , James J. Rudnick , Jessica Liberatore
IPC分类号： A61B17/32
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B2010/0225 , A61B2017/00084 , A61B2017/00792 , A61B2017/00902 , A61B2017/00969 , A61B2017/320028 , A61B2018/00005 , A61M1/0062 , A61M1/0064 , A61M2202/08
摘要： A device for repositioning tissue includes a hand held main body having a housing which defines a chamber for holding tissue. The chamber is connected to a negative pressure source to create a vacuum in the chamber. A flexible cannula is affixed to the main body, and includes a distal end and a proximate end, with openings through the thickness of the walls of each. The cannula defines a hollow lumen which is in communication with the distal end opening and the proximate end opening and the tissue holding chamber. The distal end of the cannula may be positioned in proximity to a patient's body to receive tissue therefrom through the distal end opening and to transport the tissue through the lumen and proximate end opening to the tissue holding chamber in response to the vacuum created in the tissue holding chamber.
摘要翻译：用于重新定位组织的装置包括手持主体，其具有限定用于保持组织的室的壳体。腔室连接到负压源以在腔室中产生真空。柔性套管固定到主体上，并且包括远端和近端，其中穿过每个壁的厚度的开口。套管限定了与远端开口和近端开口以及组织保持室连通的中空管腔。套管的远端可以定位在患者身体附近以通过远端开口接收组织，并且响应于在组织中产生的真空而将组织输送通过内腔和近端端开口到组织保持室控股室

26. 发明授权

US07220272B2 Composite staple and method for using same 有权
标题翻译：复合钉及其使用方法
公开(公告)号：US07220272B2
公开(公告)日：2007-05-22
申请号：US10463648
申请日：2003-06-17
申请人： Kevin S. Weadock
发明人： Kevin S. Weadock
IPC分类号： A61D1/00 , A61B17/08
CPC分类号： A61B17/11 , A61B17/0644 , A61B2017/00004 , A61B2017/00243 , A61B2017/00867 , A61B2017/0641 , A61B2017/1107 , A61B2017/1135 , A61B2017/1139
摘要： An anastomosis staple comprising of a plurality of vessel engaging members and a binding structure holding the vessel engaging members together is described. The binding structure has at least one bioabsorbable element. The binding structure is rigid enough to allow for deployment and quickly resorbs to avoid problems associated with intimal hyperplasia and physical hindrance of secondary interventional procedures. The vessel engaging members may be comprised of superelastic or shape memory metal and are independent from one another. The members may be equidistant from one another and embedded within the binding structure. The composite staple can preferably serve as a drug delivery vehicle.
摘要翻译：描述了包括多个容器接合构件和将容器接合构件保持在一起的装订结构的吻合钉。结合结构具有至少一个生物可吸收元件。结合结构刚性足以允许部署并快速吸收，以避免与内膜增生和二次介入手术的物理障碍相关的问题。容器接合构件可以由超弹性或形状记忆金属组成并且彼此独立。构件可以彼此等距并且嵌入绑定结构内。复合钉可优选用作药物递送载体。

27. 发明授权

US06616661B2 Surgical device for clamping, ligating, and severing tissue 失效
公开(公告)号：US06616661B2
公开(公告)日：2003-09-09
申请号：US09967204
申请日：2001-09-28
申请人： Parris S. Wellman , Kevin S. Weadock , Robert Nering
发明人： Parris S. Wellman , Kevin S. Weadock , Robert Nering
IPC分类号： A61B1732
CPC分类号： A61B18/1482 , A61B17/00008 , A61B18/1442 , A61B2018/00404 , A61B2018/00595 , A61B2018/00601 , A61B2018/1412 , A61B2018/1455
摘要： A surgical device for severing tissue, the surgical device comprising; a first shaft having a first internal lumen and a first slot disposed at a distal end; a clamp slidingly disposed in the first slot between open and closed positions to capture tissue in the first slot, the clamp having a clamping surface disposed at a distal end; at least one electrode for applying RF energy to the tissue captured in the first slot; a cutting blade slidingly disposed in the first slot between open and closed positions, the cutting blade having a cutting edge to sever the tissue; first actuation means for actuating the clamp between the open and closed positions; and second actuation means for actuating the cutting blade between the open and closed positions.

28. 发明授权

US6110184A Introducer with vascular sealing mechanism 失效
标题翻译：导管与血管密封机制
公开(公告)号：US6110184A
公开(公告)日：2000-08-29
申请号：US366900
申请日：1999-08-04
申请人： Kevin S. Weadock
发明人： Kevin S. Weadock
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00637 , A61B2017/00654 , A61B2017/00672
摘要： An introducer for use in interventional vascular procedures having a sealing mechanism for closure of a puncture site is disclosed. The introducer has a vessel-engaging component and a sealing component thereon. The vessel-engaging component comprises an elongated filament engaged within a channel in the wall of the introducer. The filament has an expandable part that is changeable from a first configuration to a second, expanded configuration. When the distal end of the introducer is inserted into the lumen of a blood vessel, the expandable part may be inflated. Pulling the introducer through the puncture in a direction opposite the vessel then causes the expandable member to be engaged on the vessel wall at the location of the puncture to provide resistance in pulling the introducer away from the blood vessel. In this way, the vessel-engaging component locates the puncture site. The sealing component comprises an applicator and a plurality of rings comprised of thrombogenic materials such as collagen on the wall of the introducer. The applicator is used to position the rings at the puncture site once it is located with the vessel-engaging component.
摘要翻译：公开了一种用于介入血管手术的导引器，其具有用于封闭穿刺部位的密封机构。引导器在其上具有容器接合部件和密封部件。容器接合部件包括细长的细丝，其接合在引导器的壁中的通道内。灯丝具有可从第一配置改变到第二扩展配置的可扩展部件。当导引器的远端插入血管的内腔时，可膨胀部分可以被充气。通过与容器相反的方向穿过穿刺引导器，然后使得可扩张构件在穿刺位置处接合在血管壁上，以在将引导器拉离血管时提供阻力。以这种方式，容器接合部件定位穿刺部位。密封部件包括施用器和由引导器的壁上的血栓形成材料（例如胶原）组成的多个环。一旦它与容器接合部件定位，则施用器用于将环定位在穿刺部位。

29. 发明授权

US07611484B2 Methods and devices for treating diseased blood vessels 有权
标题翻译：用于治疗患病血管的方法和装置
公开(公告)号：US07611484B2
公开(公告)日：2009-11-03
申请号：US10833614
申请日：2004-04-28
申请人： Parris S. Wellman , Kevin S. Weadock
发明人： Parris S. Wellman , Kevin S. Weadock
IPC分类号： A61M29/00
CPC分类号： A61M37/0015 , A61M25/1011 , A61M29/02 , A61M37/00 , A61M2025/105 , A61M2025/1052 , A61M2025/1086 , A61M2037/003
摘要： The present invention provides a mechanism by which the physical properties of diseased blood vessel walls can be manipulated to achieve an effective vessel lumen diameter for a prolonged period of time. The methods and devices of the present invention selectively isolate and treat the medial or adventitial layers of these diseased blood vessels. The invention is based on the delivery of proteolytic enzymes and crosslinking agents via specialized delivery devices to a select layer of the diseased blood vessel wall. By isolating and treating these layers of the artery, collagen degrading and collagen crosslinking agents can be delivered so as to affect the diameter of the blood vessels and control blood flow therein.
摘要翻译：本发明提供了一种机制，通过该机制可以操纵患病血管壁的物理性能以在更长的时间内实现有效的血管腔直径。本发明的方法和装置选择性地分离和治疗这些患病血管的内侧或外膜层。本发明基于通过专门的递送装置将蛋白水解酶和交联剂递送到患病血管壁的选择层。通过分离和处理这些动脉层，可以递送胶原蛋白降解和胶原交联剂，以便影响血管的直径并控制其中的血流。

30. 发明申请

US20080208251A1 Device for attaching, relocating and reinforcing tissue and methods of using same 有权
标题翻译：用于附着，重新定位和加强组织的装置及其使用方法
公开(公告)号：US20080208251A1
公开(公告)日：2008-08-28
申请号：US12151235
申请日：2008-05-05
申请人： Kevin S. Weadock , Parris Wellman , Martin Weisberg , Philip Prentice , Earl Adamy
发明人： Kevin S. Weadock , Parris Wellman , Martin Weisberg , Philip Prentice , Earl Adamy
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B2017/00004 , A61B2017/00743 , A61B2017/00778 , A61B2017/00805 , A61B2017/0412 , A61B2017/0427 , A61B2017/0454 , A61B2017/0458 , A61B2017/0462 , A61B2017/0464 , A61F2/0045
摘要： A device for attaching, relocating or reinforcing tissue includes a first tissue anchoring portion having a support plate and a plurality of barbs extending from the support plate for engaging tissue at a first location, a second tissue anchoring portion having a support plate and a plurality of barbs extending from the support plate for engaging tissue at a second location which is different from the first location, and a connection element, such as a suture or a mesh structure, interposed between and interconnecting the first tissue anchoring portion and the second tissue anchoring portion. The support plate of at least one of the first tissue anchoring portion and the second tissue anchoring portion may have longitudinally axially formed therethrough a bore for receiving the connecting element so that the surgeon may pull on the end of the connecting element to adjust the distance between the first tissue anchoring portion and the second tissue anchoring portion.
摘要翻译：用于附接，重新定位或加强组织的装置包括具有支撑板的第一组织锚固部分和从支撑板延伸的多个倒钩，用于在第一位置处接合组织，第二组织锚定部分具有支撑板和多个从支撑板延伸的倒钩，用于在不同于第一位置的第二位置处接合组织;以及连接元件，例如缝合线或网状结构，插入在第一组织锚固部分和第二组织锚定部分之间并将其互连。第一组织锚固部分和第二组织锚固部分中的至少一个的支撑板可以纵向轴向地形成在其中，用于接收连接元件的孔，使得外科医生可以在连接元件的端部上拉动以调节第一组织锚定部分和第二组织锚定部分。

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