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21. 发明专利

SG11201911865TA LIGHT DETECTION DEVICES WITH PROTECTIVE LINER AND METHODS RELATED TO SAME 未知
公开(公告)号：SG11201911865TA
公开(公告)日：2020-01-30
申请号：SG11201911865T
申请日：2018-11-20
申请人： ILLUMINA INC
发明人： CAI XIUYU , PINTO JOSEPH FRANCIS , BAKER THOMAS A , FUNG TRACY HELEN
IPC分类号： H01L27/146
摘要： Light detection devices and related methods are provided. The devices may comprise a reaction structure for containing a reaction solution with a relatively high or low pH and a plurality of reaction sites that generate light emissions. The devices may comprise a device base comprising a plurality of light sensors, device circuitry coupled to the light sensors, and a plurality of light guides that block excitation light but permit the light emissions to pass to a light sensor. The device base may also include a shield layer extending about each light guide between each light guide and the device circuitry, and a protection layer that is chemically inert with respect to the reaction solution extending about each light guide between each light guide and the shield layer. The protection layer prevents reaction solution that passes through the reaction structure and the light guide from interacting with the device circuitry.

22. 发明专利

AU2019214867A1 Structure and method to use active surface of a sensor 未知
公开(公告)号：AU2019214867A1
公开(公告)日：2020-01-02
申请号：AU2019214867
申请日：2019-01-29
申请人： ILLUMINA INC
发明人： LU DONGLAI , CAI XIUYU , FENG WENYI , TRAN HAI
IPC分类号： G01N21/17 , H01L27/146
摘要： Disclosed is an apparatus and method of forming, including a supporting structure, a sensor on the supporting structure, a pair of columns on the supporting structure at opposite sides of the sensor, the pair of columns having a column height relative to a top surface of the supporting structure, the column height being higher than a height of the active surface of the sensor relative to the top surface of the supporting structure, and a lidding layer on the pair of columns and over the active surface, the lidding layer being supported at opposite ends by the pair of columns. The active surface of the sensor, the lidding layer and the pair of columns form an opening above at least more than about half of the active surface of the sensor, and the supporting structure, the sensor, the lidding layer and the pair of columns together form a flow cell.

23. 发明专利

AU2018397303A1 Image sensor structure 未知
公开(公告)号：AU2018397303A1
公开(公告)日：2020-01-02
申请号：AU2018397303
申请日：2018-11-02
申请人： ILLUMINA INC
发明人： CAI XIUYU , AGAH ALI , FUNG TRACY H , DEHLINGER DIETRICH
IPC分类号： H01L27/146
摘要： An example image sensor structure includes an image layer. The image layer includes an array of light detectors disposed therein. A device stack is disposed over the image layer. An array of light guides is disposed in the device stack. Each light guide is associated with at least one light detector of the array of light detectors. A passivation stack is disposed over the device stack. The passivation stack includes a bottom surface in direct contact with a top surface of the light guides. An array of nanowells is disposed in a top layer of the passivation stack. Each nanowell is associated with a light guide of the array of light guides. A crosstalk blocking metal structure is disposed in the passivation stack. The crosstalk blocking metal structure reduces crosstalk within the passivation stack.

24. 发明专利

PL3615922T3 CZUJNIKI WYPOSAŻONE W ZINTEGROWANY OBWÓD ZABEZPIECZAJĄCY 未知
公开(公告)号：PL3615922T3
公开(公告)日：2022-10-10
申请号：PL18791184
申请日：2018-04-19
申请人： ILLUMINA INC
发明人： FUNG TRACY HELEN , CAI XIUYU , KWOK LISA , TRAN HAI , SAMIEE KEVAN , QIANG LIANGLIANG , BOYANOV BOYAN
IPC分类号： G01N33/543 , B01L3/00 , C12Q1/68 , G01N21/62 , G01N21/64 , G01N21/77

25. 发明专利

SA519410860B1 بنية مستشعر صورة 未知
公开(公告)号：SA519410860B1
公开(公告)日：2022-08-17
申请号：SA519410860
申请日：2019-12-19
申请人： ILLUMINA INC
发明人： AGAH ALI , DEHLINGER DIETRICH , FUNG TRACY H , CAI XIUYU
摘要： يتعلقالاختراعالحاليببنيةمستشعرصورة image sensor structure (100, 200, 300, 400) نموذجيةعلىطبقةصورة image layer (38, 40, 108). وتشتملطبقةالصورة (38, 40, 108) علىمجموعةمنكواشفالضوء light detectors (112) الموضوعةفيهذهالطبقة. مجموعةجهاز device stack (126) موضوعةعلىطبقةالصورة (38, 40, 108). مجموعةموجهاتضوء light guides (130) موضوعةفيمجموعةالجهاز(126). كلموجهضوء light guide يصحبهكاشفضوء light detector (24) واحدعلىالأقلمنمجموعةكواشفالضوء (126). مجموعةإيقاف passivation stack (24) موضوعةعلىمجموعةالجهاز(126). وتشتملمجموعةالإيقاف (24) علىسطحسفلي (60) فيتلامسمباشرمعسطحعلويلموجهاتالضوء (50). مجموعةعيوننانوية nanowells (26) موضوعةفيطبقةعلويةفيمجموعةالإيقاف (24). ويصحبكلعيننانوية nanowell (26) موجهضوء light guide منمجوعةموجهاتالضوء (130). بنيةفلزيةلمنعالتداخل crosstalk blocking metal structure (102) موضوعةفيمجموعةالإيقاف (24). تعملالبنيةالفلزية (102) لمنعالتداخلعلىالحدمنالتداخلفيمجموعةالإيقاف (24). شكل 1

26. 发明专利

BR112019027631B1 Estrutura e método para uso de superfície ativa de um sensor 未知
公开(公告)号：BR112019027631B1
公开(公告)日：2022-06-07
申请号：BR112019027631
申请日：2019-01-29
申请人： ILLUMINA INC
发明人： LU DONGLAI , TRAN HAI , FENG WENYI , CAI XIUYU
IPC分类号： G01N21/17 , H01L27/146
摘要： é divulgado um aparelho e método de formação, incluindo uma estrutura de suporte, um sensor na estrutura de suporte, um par de colunas na estrutura de suporte em lados opostos do sensor, o par de colunas tendo uma altura de coluna em relação a uma superfície superior da estrutura de suporte, a altura da coluna sendo superior à altura da superfície ativa do sensor em relação à superfície superior da estrutura de suporte e uma camada de cobertura no par de colunas e sobre a superfície ativa, sendo a camada de cobertura suportada em extremidades opostas pelo par de colunas. a superfície ativa do sensor, a camada de cobertura e o par de colunas formam uma abertura acima de pelo menos mais da metade da superfície ativa do sensor e a estrutura de suporte, o sensor, a camada de cobertura e o par de colunas juntos formar uma célula de fluxo.

27. 发明专利

ES2836505T3 Dispositivos de detección de luz con revestimiento de protección y métodos relacionados con este 未知
公开(公告)号：ES2836505T3
公开(公告)日：2021-06-25
申请号：ES18215873
申请日：2018-12-24
申请人： ILLUMINA INC
发明人： CAI XIUYU , PINTO JOSEPH FRANCIS , BAKER THOMAS A , FUNG TRACY HELEN
IPC分类号： G01N21/64 , G01N21/05
摘要： Un dispositivo (104), que comprende: una estructura de reacción (126) que forma una pluralidad de cavidades de reacción (108) para contener una solución de reacción con un pH menor o igual a aproximadamente 5 o un pH mayor o igual a aproximadamente 8 y al menos un sitio de reacción (114) que genera emisiones de luz en respuesta a la luz de excitación incidente después del tratamiento con la solución de reacción; y una base del dispositivo (125) que se coloca debajo de la estructura de reacción (126), que comprende: una base del sensor (141); una pluralidad de sensores de luz (140) que se incluyen en la base del sensor (141); capas de material dieléctrico (142) apiladas en la base del sensor (141); circuitos del dispositivo (146) acoplados eléctricamente a los sensores de luz (140) para transmitir señales de datos con base en fotones detectados por los sensores de luz (140), en donde los circuitos del dispositivo (146) se proporcionan dentro de las capas de material dieléctrico (142); una pluralidad de guías de luz (118) con regiones de entrada (158) que se disponen para recibir la luz de excitación y las emisiones de luz de al menos una cavidad de reacción (108) correspondiente, las guías de luz (118) que se extienden dentro de la base del dispositivo (125) a través de las capas de material dieléctrico (142) desde las regiones de entrada (158) hacia al menos un sensor de luz (140) correspondiente y las guías de luz (118) que comprenden al menos un material de filtro (116) que se dispone para filtrar la luz de excitación y permitir que las emisiones de luz pasen al al menos un sensor de luz (140) correspondiente; una capa de revestimiento (154) que se extiende sobre la base del dispositivo (125) y alrededor de las superficies laterales de cada guía de luz (118) y se coloca entre cada guía de luz (118) y los circuitos del dispositivo (146); una capa de protección (130) que se extiende alrededor de cada guía de luz (118) y se coloca entre el material de filtro (116) de cada guía de luz (118) y la capa de revestimiento (154), la capa de protección (130) que se dispone para evitar que la solución de reacción que pasa a través de la estructura de reacción (126) y la guía de luz (118) interactúe con los circuitos del dispositivo (146), en donde la capa de protección (130) es químicamente inerte con respecto a la solución de reacción con un pH menor o igual a aproximadamente 5 o un pH mayor o igual a aproximadamente 8; y una primera capa de blindaje (150) que se extiende entre las regiones de entrada adyacentes (158) para bloquear la luz de excitación y las emisiones de luz incidente en la primera capa de blindaje (150), en donde la primera capa de blindaje (150) se coloca debajo de la capa de revestimiento (154) y en contacto con las capas de material dieléctrico (142).

28. 发明专利

AU2020364314A1 Image sensor structure 未知
公开(公告)号：AU2020364314A1
公开(公告)日：2021-06-17
申请号：AU2020364314
申请日：2020-09-29
申请人： ILLUMINA INC
发明人： EMADI ARVIN , AGAH ALI , CAI XIUYU , HETHERINGTON CRAIG LEE
IPC分类号： H01L27/146
摘要： An image sensor structure including an image stack disposed over a device stack. The image stack includes a plurality of light detectors. A first optical filter stack is disposed over the image stack. The first optical filter stack includes a light guide layer. Light pipe cavities are disposed in the light guide layer. Each light pipe cavity is associated with a light detector. Each light pipe cavity has an aspect ratio that is greater than about 2.5 to about 1. A nanowell layer is disposed over the first optical filter stack. Nanowells are disposed in the nanowell layer. Each nanowell is associated with a light detector.

29. 发明专利

AU2021201666A1 Light Detection Devices with Protective Liner and Methods Related to Same 未知
公开(公告)号：AU2021201666A1
公开(公告)日：2021-04-08
申请号：AU2021201666
申请日：2021-03-16
申请人： ILLUMINA INC
发明人： CAI XIUYU , PINTO JOSEPH FRANCIS , BAKER THOMAS A , FUNG TRACY HELEN
IPC分类号： H01L27/146
摘要： A device is disclosed, comprising: a reaction structure that forms a plurality of reaction recesses; and a device base positioned beneath the reaction structure, comprising: a plurality of light sensors; device circuitry electrically coupled to the light sensors to transmit data signals based on photons detected by the light sensors; a plurality of light guides with input regions that receive excitation light and light emissions from at least one corresponding reaction recess of the reaction recesses, each light guide extending into the device base toward at least one corresponding light sensor of the light sensors, and said light guides comprising at least one filter material that filters the excitation light and permits the light emissions to pass to the at least one corresponding light sensor; and a protection layer extending about each light guide, where the protection layer is chemically inert with respect to a reaction solution that passes over the reaction structure.

30. 发明专利

SG11202012643QA FLOW CELL SYSTEMS AND METHODS RELATED TO SAME 未知
公开(公告)号：SG11202012643QA
公开(公告)日：2021-01-28
申请号：SG11202012643Q
申请日：2019-11-08
申请人： ILLUMINA INC
发明人： RIVAL ARNAUD , AGAH ALI , DEHLINGER DIETRICH , FUNG TRACY H , CAI XIUYU
IPC分类号： C12M1/00 , C12Q1/00 , G01N21/64
摘要： Flow cells systems and corresponding methods are provided. The flow cells systems may include a socket comprising a base portion, a plurality of electrical contacts and a cover portion that includes a first port. The flow cells systems may also include a flow cell device secured within an enclosure of the socket. The flow cell device may comprise a frameless light detection device comprising a base wafer portion, a plurality of dielectric layers, a reaction structure, a plurality of light guides, a plurality of light sensors, and device circuitry electrically coupled to the light sensors. The flow cell device may also comprise a lid forming a flow channel over the reaction structure that includes a second port in communication with the flow channel and the first port of the socket. The device circuity of the light detection device may be electrically coupled to the electrical contacts of the socket.

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