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21. 发明授权

US5766224A Temporary, post-heart surgery cardioverting and pacing system and lead systems for use therein 失效
标题翻译：临床，心脏手术后心脏转复和起搏系统及其使用的引导系统
公开(公告)号：US5766224A
公开(公告)日：1998-06-16
申请号：US627688
申请日：1996-04-02
申请人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
发明人： Clifton A. Alferness , John M. Adams , Gregory M. Ayers , Hugo X. Gonzalez
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/3962 , A61N1/0587
摘要： A post-surgical atrial cardioverting, atrial pacing, and ventricular pacing system and lead system provides for cardioverting the atria, pacing the atria, and/or pacing the ventricles of the heart of a post-surgical heart patient. The system includes a first lead and a second lead providing a pair of atrial cardioverting electrodes, an atrial pacing electrode, and a ventricular pacing electrode. The electrodes are electrically isolated from each other. The system further includes at least one anchor releasably disposing the electrodes beneath the skin of the patient with each atrial cardioverting electrode electrically contacting a respective given one of the atria, the atrial pacing electrode electrically contacting one of the atria, and the ventricular pacing electrode electrically contacting a ventricle. The system further includes at least one of an external cardiovertor coupled to the cardioverting electrodes for cardioversion, an external atrial pacer coupled to the atrial pacing electrode and one of the atrial cardioverting electrodes for pacing the atria, and an external ventricular pacer coupled to the ventricular pacing electrode and one of the atrial cardioverting electrodes for pacing the ventricles.
摘要翻译：手术后心房心律转复，心房起搏和心室起搏系统和牵引系统提供心脏转移心房，起搏心房和/或起搏手术后心脏病人心脏的心室。该系统包括提供一对心房心脏转复电极，心房起搏电极和心室起搏电极的第一引线和第二引线。电极彼此电隔离。所述系统还包括至少一个锚定器，其可释放地将电极设置在患者皮肤下方，每个心房心脏转复电极与相应的心房起搏器电气接触，心房起搏电极与心房起搏器电气接触，接触心室。该系统还包括耦合到用于心脏复律的复律电极的外部心脏转换器中的至少一个，耦合到心房起搏电极的外部心房起搏器和用于起搏心房的心房心律转换电极之一和与心室联接的外部心室起搏器起搏电极和心房心律转复电极之一用于起搏心室。

22. 发明授权

US5279291A Method for atrial defibrillation 失效
标题翻译：心房除颤方法
公开(公告)号：US5279291A
公开(公告)日：1994-01-18
申请号：US924323
申请日：1992-08-03
申请人： John M. Adams , Clifton A. Alferness
发明人： John M. Adams , Clifton A. Alferness
IPC分类号： A61N1/05 , A61N1/39
CPC分类号： A61N1/3918 , A61N1/056 , A61N1/0563 , A61N1/3956 , A61N1/3962 , A61N1/395 , A61N1/3987 , A61N2001/0585
摘要： An implantable atrial defibrillator provides a pulse of defibrillating electrical energy to the atria of the heart in synchronism with sensed R waves in response to non-coincident sensing of an R wave at first and second areas of the heart. The defibrillating pulse is provided after a predetermined number of consecutive R waves are non-coincidently sensed to assure reliable synchronization. The atrial defibrillator is also operational in a marker mode wherein a number of synchronization marker pulses are delivered to the heart for detection on an externally generated electrocardiogram. The atrial fibrillation detector of the defibrillator is normally disabled and is activated when the sensed ventricular activity indicates a probability of atrial fibrillation to conserve a depletable power source. An endocardial lead is also described which ensures that the delivered atrial defibrillating electrical energy is substantially confined to the atria of the heart.
摘要翻译：可植入心房除颤器响应于在心脏的第一和第二区域处的R波的不一致的感测，与感测到的R波同步地向心脏的心房提供除颤电脉冲。在不一致地感测到预定数量的连续R波之后提供除颤脉冲，以确保可靠的同步。心房除颤器还可以在标记模式中操作，其中多个同步标记脉冲被传送到心脏以便在外部产生的心电图上进行检测。除颤器的心房颤动检测器通常被禁用，并且当感测到的心室活动指示心房颤动的概率以节省可消耗的电源时被激活。还描述了一种心内膜导联，其确保输送的心房除颤电能基本上限于心脏的心房。

23. 发明授权

US5251748A Dual half-carton structure and method of forming same 失效
标题翻译：双半纸箱结构及其形成方法
公开(公告)号：US5251748A
公开(公告)日：1993-10-12
申请号：US901682
申请日：1992-06-22
申请人： John M. Adams , Christopher N. Chance , James A. DeBlasio , Donald H. Evers , Michael A. Kirby , Reginald W. Newsome , Robert E. Talley
发明人： John M. Adams , Christopher N. Chance , James A. DeBlasio , Donald H. Evers , Michael A. Kirby , Reginald W. Newsome , Robert E. Talley
IPC分类号： B65D5/54 , B65D85/10
CPC分类号： B65D85/1072 , B65D5/5495 , B65D2203/06
摘要： A method of attaching two containers wherein two containers faced toward each other are secured by cooperation of at least one tab on the front wall of one container and at least one slot on the front wall of the other container, and the dual container structure formed thereby. The slot and tab act to securely attach the two containers such that the containers may easily be separated for later sale as independent units.
摘要翻译：一种连接两个容器的方法，其中两个容器朝向彼此面对，通过在一个容器的前壁上的至少一个突出部和另一个容器的前壁上的至少一个槽的协作来固定，由此形成的双重容器结构。狭槽和标签用于牢固地连接两个容器，使得容器可以容易地分离以供以后作为独立单元销售。

24. 发明授权

US5178270A Easily sealable, openable, and reclosable carton 失效
标题翻译：容易密封，可开启和可重新封闭的纸箱
公开(公告)号：US5178270A
公开(公告)日：1993-01-12
申请号：US892766
申请日：1992-06-03
申请人： John M. Adams , Christopher N. Chance , James A. DeBlasio , Donald H. Evers , William C. Harris, Jr. , Michael A. Kirby, Sr. , Reginald W. Newsome , Robert E. Talley
发明人： John M. Adams , Christopher N. Chance , James A. DeBlasio , Donald H. Evers , William C. Harris, Jr. , Michael A. Kirby, Sr. , Reginald W. Newsome , Robert E. Talley
IPC分类号： B65D5/54 , B65D85/10
CPC分类号： B65D85/1072 , B65D5/5495 , B65D2203/06 , Y10S206/813
摘要： A cigarette carton formed from a blank in which the front and rear long walls of the carton are joined along a side wall instead of along a top or bottom wall. The carton thus has two sets of closure flaps, one set along the top end and another set along the bottom end. At least one set of closure flaps is a set of lap flaps, which are easily opened by a tax-stamping machine and easily closed by a machine. Preferably the other set of closure flaps is a tuck-in flap which is easily openable and reclosable by a consumer. Also disclosed is a multiple unit carton formed by applying adhesive bearing carrier means across top and bottom walls of the adjoining cartons. The multiple unit carton may be separated by a retailer or consumer for purchase of the individual component cartons.
摘要翻译：由坯料形成的香烟纸盒，其中纸箱的前后长壁沿着侧壁而不是沿着顶壁或底壁连接。因此，纸箱具有两组闭合襟翼，一组沿着顶端设置，另一组沿着底端。至少有一组闭合襟翼是一组襟翼，可以通过一台税务打印机轻松打开，并可以轻松地被机器关闭。优选地，另一组闭合襟翼是可容易地打开并可由消费者重新关闭的折叠式折翼。还公开了通过将邻接纸箱的顶壁和底壁施加粘合剂轴承承载装置形成的多单元纸箱。多个单元纸盒可以由零售商或消费者分开以购买单个部件纸箱。

25. 发明授权

US09044618B2 Shockwave valvuloplasty catheter system 有权
公开(公告)号：US09044618B2
公开(公告)日：2015-06-02
申请号：US12611997
申请日：2009-11-04
申请人： Daniel Hawkins , John M. Adams
发明人： Daniel Hawkins , John M. Adams
IPC分类号： A61B17/22 , A61N1/38 , A61M25/10 , A61N1/05
CPC分类号： A61B17/22022 , A61B2017/22025 , A61B2017/22054 , A61B2017/22061 , A61B2017/22062 , A61B2017/22068 , A61B2017/22098 , A61M25/1002 , A61M2025/1072 , A61N1/056 , A61N1/38
摘要： A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

26. 发明授权

US08430891B2 Transesophageal gastric reduction device, system and method 有权
标题翻译：经食道胃减压装置，系统及方法
公开(公告)号：US08430891B2
公开(公告)日：2013-04-30
申请号：US13069992
申请日：2011-03-23
申请人： Stefan J. M. Kraemer , John M. Adams
发明人： Stefan J. M. Kraemer , John M. Adams
IPC分类号： A61B17/12
CPC分类号： A61F5/0086 , A61B17/122 , A61B17/1285 , A61B2017/00818 , A61B2017/308 , A61F2/91
摘要： A gastric reduction system and method provides for transesophageal formation of a gastric reduction pouch of the stomach. The system includes an expandable structure, which may be placed in a stomach and expanded to occupy a fractional volume of the stomach. An evacuator is then fed through the expandable structure and utilized to deflate the stomach and draw the stomach to and around the expandable structure to form the gastric reduction pouch. A self-deploying fastener is then deployed to maintain the gastric reduction pouch.
摘要翻译：胃减压系统和方法提供胃的胃减压袋的经食道形成。该系统包括可扩张结构，其可以放置在胃中并且膨胀以占据胃的分数体积。然后将排气器通过可膨胀结构进料，并用于使胃胀开，并将胃抽吸到可膨胀结构周围并围绕可膨胀结构并形成胃减压袋。然后展开自展展紧固件以维持胃减压袋。

27. 发明授权

US08337523B2 Tissue fixation assembly having prepositioned fasteners and method 有权
标题翻译：具有预定位紧固件和方法的组织固定组件
公开(公告)号：US08337523B2
公开(公告)日：2012-12-25
申请号：US12460247
申请日：2009-07-15
申请人： Steve G. Baker , Brett J. Carter , Stefan J. M. Kraemer , Clifton A. Alferness , John M. Adams , Raymond Michael Wolniewicz, III
发明人： Steve G. Baker , Brett J. Carter , Stefan J. M. Kraemer , Clifton A. Alferness , John M. Adams , Raymond Michael Wolniewicz, III
IPC分类号： A61B17/10 , A61B17/08
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/064 , A61B17/068 , A61B17/1114 , A61B2017/00827 , A61B2017/0409 , A61B2017/0414 , A61B2017/0419
摘要： A tissue fastener assembly delivers a fastener for deployment. The assembly includes a fastener including a first member, a second member, the first and second members having first and second ends, and a flexible connecting member fixed to each of the first and second members intermediate the first and second ends and extending between the first and second members. The first member has a longitudinal axis and a through channel along the axis. The assembly further includes a deployment wire slidingly received within the through channel of the first member that pierces into the tissue and guides the first member through the tissue, a guide structure defining a lumen that receives the fastener and deployment wire and guides the deployment wire and fastener to the tissue, and a fastener configuration structure that orientates the second member in a predetermined position relative to the first member within the lumen for dependable deployment.
摘要翻译：组织紧固件组件递送用于展开的紧固件。所述组件包括紧固件，所述紧固件包括第一构件，第二构件，所述第一和第二构件具有第一和第二端;以及柔性连接构件，其固定到所述第一和第二构件中的每一个，所述第一和第二构件在所述第一和第二端之间延伸，和第二名成员。第一构件具有沿轴线的纵向轴线和贯通通道。组件还包括滑动地容纳在第一构件的穿过通道内的展开线，其穿透组织并引导第一构件穿过组织;限定内腔的引导结构，其接纳紧固件和展开线并引导展开线，并且紧固件到组织，以及紧固件配置结构，其将第二构件相对于管腔内的第一构件定位在预定位置以进行可靠的展开。

28. 发明授权

US08226607B2 Disposable infusion device with dual valve system 有权
标题翻译：具有双阀系统的一次性输液装置
公开(公告)号：US08226607B2
公开(公告)日：2012-07-24
申请号：US11906130
申请日：2007-09-28
申请人： Brett J. Carter , John M. Adams
发明人： Brett J. Carter , John M. Adams
IPC分类号： A61M1/00
CPC分类号： A61M5/14248 , A61M5/1424 , A61M5/145
摘要： A wearable infusion device comprises a first control movable between a first position and a second position that when in the first position, establishes a first fluid path between a reservoir and a pump and when in the second position, establishes a second fluid path between the pump and an outlet. A second control actuates the pump only when the second fluid path has been established by the first control.
摘要翻译：可穿戴输注装置包括可在第一位置和第二位置之间移动的第一控制器，当在第一位置时，在第一位置建立储存器和泵之间的第一流体路径，并且当处于第二位置时，在泵之间建立第二流体路径和一个出口。只有当第二流体路径已经被第一控制建立时，第二控制仅启动泵。

29. 发明申请

US20110202078A1 TRANSORAL ENDOSCOPIC GASTROESOPHAGEAL FLAP VALVE RESTORATION DEVICE, ASSEMBLY, SYSTEM AND METHOD 审中-公开
公开(公告)号：US20110202078A1
公开(公告)日：2011-08-18
申请号：US13095777
申请日：2011-04-27
申请人： Stefan J. M. Kraemer , John M. Adams , Stephen T. Vincent
发明人： Stefan J. M. Kraemer , John M. Adams , Stephen T. Vincent
IPC分类号： A61B17/11
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0644 , A61B17/07207 , A61B2017/003 , A61B2017/00827 , A61B2017/00867 , A61B2017/07214 , A61B2017/2905 , A61B2017/2926 , A61B2017/306
摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.

30. 发明授权

US07942887B2 Transoral endoscopic gastroesophageal flap valve restoration device, assembly, system and method 有权
标题翻译：经内镜胃食管瓣瓣修复装置，组装，系统及方法
公开(公告)号：US07942887B2
公开(公告)日：2011-05-17
申请号：US10864946
申请日：2004-06-10
申请人： Stefan J. M. Kraemer , John M. Adams , Stephen T. Vincent
发明人： Stefan J. M. Kraemer , John M. Adams , Stephen T. Vincent
IPC分类号： A61B19/00
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0644 , A61B17/07207 , A61B2017/003 , A61B2017/00827 , A61B2017/00867 , A61B2017/07214 , A61B2017/2905 , A61B2017/2926 , A61B2017/306
摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.
摘要翻译：本发明提供了一种用于胃食管瓣瓣的经口内镜恢复的装置，组装和方法。本发明还提供了一种用于组织固定的自动转向和自闭合组织固定装置，以及用于夹紧和操纵组织的起搏装置。所述修复装置包括纵向构件，所述纵向构件设置成横向放置在胃中，承载在所述纵向构件上的组织整形器，其使胃组织呈现与胃食管瓣相关的形状;以及组织固定装置，其将所述成形胃部组织保持在形状近似于胃食管皮瓣。组织整形器可以包括模具。该装置可以包括用于夹持和操纵食管组织以帮助恢复胃食管瓣的入口装置，并且可以包括组织固定装置。

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