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21. 发明申请

WO2022022894A1 DIALYSIS SYSTEM AND METHOD INCLUDING A FLOW PATH INSULATOR 审中-公开
公开(公告)号：WO2022022894A1
公开(公告)日：2022-02-03
申请号：PCT/EP2021/067055
申请日：2021-06-23
申请人： GAMBRO LUNDIA AB
发明人： EKDAHL, Olof , ÖRNDAL, Carl-Henry , JANSSON, Olof , LINDGREN, Henrik , NILSSON, Mats , NILSSON, Lars-Olof
IPC分类号： A61M1/28 , A61M1/36
摘要： A peritoneal dialysis system (10) includes: a cycler (20); a disposable set operable with the cycler and (40) including a patient line (50) and a drain line (56); one of (i) a water purifier (210) for supplying purified water for mixing to form fresh dialysis fluid at the disposable set (40), (ii) at least one fresh dialysis fluid container provided as part of the disposable set (40) for supplying fresh dialysis fluid, or (iii) a dialysis fluid preparation unit configured to supply fresh dialysis fluid to the disposable set (40); and at least one flow path insulator (250) provided at the cycler (20), the water purifier (210), the dialysis fluid preparation unit, and/or along the drain line (56), the flow path insulator (250) configured to separate used dialysis fluid flowing along the drain line (56) into flow segments to limit any current flowing from the patient to a drain.

22. 发明申请

WO2015101508A1 DIALYSIS MACHINE, METHOD OF CONTROLLING THE DIALYSIS MACHINE, AND COMPUTER PROGRAM FOR IMPLEMENTING THE CONTROL 审中-公开
标题翻译： DIALYSIS MACHINE，控制DIALYSIS MACHINE的方法，以及实施控制的计算机程序
公开(公告)号：WO2015101508A1
公开(公告)日：2015-07-09
申请号：PCT/EP2014/078401
申请日：2014-12-18
申请人： GAMBRO LUNDIA AB
发明人： HOBRO, Sture , JANSSON, Olof , LUNSJÖ, Jan
IPC分类号： A61M1/16
CPC分类号： A61M1/169 , A61L2/18 , A61L2/24 , A61L2202/14 , A61L2202/24 , A61M1/168 , A61M1/1682 , A61M1/1688 , A61M39/223 , A61M2205/15 , A61M2205/3331 , A61M2205/36 , A61M2205/702
摘要： A dialysis machine comprising a fluid circuit for providing a dialysis fluid to a dialyser is disclosed. The fluid circuit comprises a tube with a first valve for providing a disinfectant fluid for disinfecting at least a part of the fluid circuit at disinfection of the dialysis machine. The tube with the first valve is arranged to provide the disinfectant fluid upstream the dialyser and at a position in the fluid circuit where pressure is, during treatment, such that a pressure gradient between ports of the first valve is provided, the ports comprising at least a disinfectant fluid port and a fluid circuit port, such that the disinfectant fluid port of the first valve is enabled to be safely connected to a source of disinfectant also during treatment. A method of controlling such a dialysis machine and a computer program for controlling are also disclosed.
摘要翻译：公开了一种透析机，其包括用于向透析器提供透析流体的流体回路。流体回路包括具有第一阀的管，用于在透析机的消毒时提供用于消毒至少一部分流体回路的消毒液。具有第一阀的管被布置成在透析器上游提供消毒剂流体，并且在处理期间压力处于流体回路中的位置处使得提供第一阀的端口之间的压力梯度，该端口至少包括消毒剂流体端口和流体回路端口，使得第一阀的消毒液流体端口也能够在处理期间安全地连接到消毒剂源。还公开了一种控制这种透析机的方法和用于控制的计算机程序。

23. 发明申请

WO2015000666A1 PACKAGING OF POWDERY MATERIAL FOR PREPARATION OF A MEDICAL SOLUTION 审中-公开
标题翻译：包装用于制备医疗解决方案的粉末材料
公开(公告)号：WO2015000666A1
公开(公告)日：2015-01-08
申请号：PCT/EP2014/062112
申请日：2014-06-11
申请人： GAMBRO LUNDIA AB
发明人： SCHROEDER, Petronella , JANSSON, Olof , LINDEN, Torbjörn
IPC分类号： A61M1/16 , A61J1/10
CPC分类号： A61M1/1666 , A61J1/10 , A61J1/2093 , A61M1/167 , A61M1/287 , A61M2207/00 , B65B3/003 , B65B7/02
摘要： A package (1) is configured to store a powdery material (2) which is to be mixed with a solvent to form a medical solution, such as a dialysis solution. The package (1) comprises a filled cavity portion (6a) containing the powdery material (2), optionally separated into groups of different composition, and a tab portion (9) integrally formed with the filled cavity portion (6a) and being swept around the filled cavity portion (6a) so as to define a roll-up package. The tab portion (9) forms a protective barrier that shields the powdery material (2), e.g. by counteracting transport of moisture into and out of the package. The tab portion (9) may also stabilize the package. The roll-up package is compact, and simple to manufacture and handle.
摘要翻译：包装（1）被配置为存储与溶剂混合以形成诸如透析溶液的药物溶液的粉末状材料（2）。包装（1）包括一个包含粉状材料（2）的填充空腔部分（6a），任选地分成不同组成的组，以及与填充空腔部分（6a）整体形成并围绕填充空腔部分（6a）以限定卷起包装。突片部分（9）形成屏蔽该粉状材料（2）的保护屏障，例如，通过抵消水分进出包装的运输。突片部分（9）也可以稳定包装。卷取包装紧凑，制造和处理简单。

24. 发明申请

WO2019121167A1 DIALYSIS SYSTEM HAVING CARBON DIOXIDE GENERATION AND PRIME 审中-公开
公开(公告)号：WO2019121167A1
公开(公告)日：2019-06-27
申请号：PCT/EP2018/084368
申请日：2018-12-11
申请人： GAMBRO LUNDIA AB
发明人： HOBRO, Sture , STERNBY, Jan , LINDEN, Torbjörn , JANSSON, Olof
IPC分类号： A61M1/36
摘要： An extracorporeal therapy system includes: (i) a dialysis fluid circuit including dialysis fluid preparation structure configured to prepare a dialysis fluid for an extracorporeal therapy treatment; (ii) a blood circuit including a blood filter for use during the extracorporeal therapy treatment; (iii) a blood pump operable to pump blood through the blood circuit and blood filter; and (iv) a control unit operable with the dialysis fluid preparation structure and the blood pump, the control unit programmed to prepare a gas generation fluid different than the dialysis fluid for the extracorporeal therapy treatment, wherein the gas generation fluid generates carbon dioxide ("CO 2 ") gas, and wherein the CO 2 gas is used to prime the blood circuit including the blood filter.

25. 发明申请

WO2017193065A1 SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING TESTING THEREOF 审中-公开
标题翻译：具有使用透析流体制剂的腹膜透析的系统和方法，包括对其进行测试
公开(公告)号：WO2017193065A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/031396
申请日：2017-05-05
申请人： GAMBRO LUNDIA AB , WELLINGS, Anders
发明人： WELLINGS, Anders , WIESLANDER, Anders , JANSSON, Olof
IPC分类号： A61M1/16 , A61M1/28
摘要： A peritoneal dialysis system includes a disposable set, source(s) of concentrate(s), a water purifier, a sensor, and a control unit. The disposable set includes a water port, an inlet port, a drain port, a water line in fluid communication with the water port, a drain line in fluid communication with the drain port, and a container to hold a dialysis fluid prepared by mixing water and the concentrate(s). The source(s) of concentrate(s) are in fluid communication with the inlet port, and the water purifier is configured to purify water and feed the water towards the water port so the sensor can detect a fluid property. The control unit is configured to deliver dialysis fluid mixed in the disposable set to the drain line and water purified by the water purifier along the water line, into the disposable set, and out the drain line to push dialysis fluid to the sensor.
摘要翻译：腹膜透析系统包括一次性装置，浓缩物的来源，净水器，传感器和控制单元。一次性装置包括水端口，入口端口，排水端口，与水端口流体连通的水管线，与排水端口流体连通的排水管线以及容纳透析流体的容器，所述透析流体通过混合水和浓缩物。一种或多种浓缩物源与入口端口流体连通，并且净水器被配置为净化水并将水供给到水端口，从而传感器可以检测流体性质。控制单元被配置为将在一次性装置中混合的透析流体输送到排水管线，并且由水净化器沿着水管线净化的水进入一次性装置，并且排出排水管线以将透析流体推送到传感器。 p>

26. 发明申请

WO2017191301A1 SYSTEM FOR PROPORTIONING FLUIDS 审中-公开
标题翻译：用于配制流体的系统
公开(公告)号：WO2017191301A1
公开(公告)日：2017-11-09
申请号：PCT/EP2017/060769
申请日：2017-05-05
申请人： GAMBRO LUNDIA AB
发明人： WIESLANDER, Anders , JANSSON, Olof , CARLSSON, Ola , HOBRO, Sture , SANDIN, Karin , ENARSSON, Simon
IPC分类号： A61M1/28 , A61M1/16
CPC分类号： A61M1/287 , A61K31/19 , A61K31/194 , A61K31/7004 , A61K33/14 , A61K33/20 , A61M1/1696 , A61M2202/0488
摘要： The present invention concerns a system for preparing a ready-to-use peritoneal dialysis fluid. The system comprises a) a proportioning device; b) at least one source of water; c) at least one source of first concentrate adapted for connection with a) and b), d) at least one source of second concentrate adapted for connection with a) and b), and optionally, e) at least one source of further concentrate adapted for connection with a) and b), wherein the first concentrate comprises glucose and has a pH of between 1.5 and 4, and wherein the second concentrate comprises a physiologically acceptable buffer and has a pH of between 5.5 and 9.0.
摘要翻译：本发明涉及用于制备即用型腹膜透析液的系统。该系统包括：a）配比装置; b）至少有一个水源; c）适用于与a）和b）连接的至少一种第一浓缩物源，d）至少一种适用于与a）和b）连接的第二浓缩物源，以及任选地e）至少一种浓缩物源其适于与a）和b）连接，其中所述第一浓缩物包含葡萄糖且具有1.5至4的pH，并且其中所述第二浓缩物包含生理上可接受的缓冲剂且具有5.5至9.0的pH。

27. 发明申请

WO2017098001A1 SYSTEM AND METHOD FOR FILTRATION OF FLUIDS 审中-公开
标题翻译：用于过滤流体的系统和方法
公开(公告)号：WO2017098001A1
公开(公告)日：2017-06-15
申请号：PCT/EP2016/080487
申请日：2016-12-09
申请人： GAMBRO LUNDIA AB
发明人： JANSSON, Olof , ERICSON, Björn
IPC分类号： B01D63/04 , B01D61/28 , B01D61/30 , B01D61/58
CPC分类号： B01D63/04 , A61M1/16 , A61M1/1621 , A61M1/34 , A61M1/3403 , A61M1/3437 , B01D61/28 , B01D61/30 , B01D61/58 , B01D2313/21
摘要： A filter device (10) for filtration of fluids, in particular for the dialysis of blood. The filter device (10) comprises a housing (12) having a first end (14) and a second end (16) and defining a fluid chamber (18) extending between the first end (14) and the second end (16). The filter device (10) further comprises a first lid (20) provided at the first end (14) of the housing(12) and comprising a first fluid port (22), a first compartment (24), a second compartment (26) and a first internal separating wall (28) separating the first compartment (24) from the second compartment (26).The filter device (10) further comprises a second lid (30) provided at the second end (16) of the housing (12) and comprising a second fluid port (32), a third fluid port (33), a third compartment (34), a fourth compartment (36) and a second internal separating wall (38) separating the third compartment (34) from the fourth compartment (36). The filter device (10) further comprises a plurality of hollow fibers (40) arranged within the housing (12), wherein each of the plurality of hollow fibers (40) comprises a semi-permeable membrane and defines a fluid channel extending longitudinally through an interior of the respective hollow fiber (40).The filter device (10) further comprises a first sealing means (42) which separates the fluid chamber (18) from the first and the second compartment (24, 26), the first sealing means (42) having a first longitudinal end facing away from the second lid (30).The filter device (10) further comprises a second sealing means (46) which separates the fluid chamber (18) from the third and the fourth compartment (34, 36),the second sealing means (46) having a second longitudinal end facing away from the first lid (20). Still further, the filter device (10) comprises a fourth fluid port (50) and a fifth fluid port (52) both provided at the fluid chamber (18) and located between the first longitudinal end of the first sealing means (42) and the second longitudinal end of the second sealing means (46).
摘要翻译：用于过滤流体的过滤装置（10），特别是用于血液透析的过滤装置（10）。过滤装置（10）包括具有第一端（14）和第二端（16）并限定在第一端（14）和第二端（16）之间延伸的流体腔室（18）的壳体（12）。过滤装置10还包括设置在壳体12的第一端部14并包括第一流体端口22，第一隔室24，第二隔室26的第一盖20，）和将所述第一隔室（24）与所述第二隔室（26）隔开的第一内部分隔壁（28）。所述过滤装置（10）还包括设置在所述壳体的第二端部（16）（32），第三流体端口（33），第三隔室（34），第四隔室（36）和第二内部隔离壁（38），所述第三隔室（34）与所述第三隔室（34）从第四隔室（36）排出。过滤装置（10）还包括布置在壳体（12）内的多根中空纤维（40），其中多根中空纤维（40）中的每一根包括半渗透膜并且限定纵向延伸穿过（40）的内部。过滤装置（10）还包括将流体腔室（18）与第一和第二隔室（24,26）分开的第一密封装置（42），第一密封装置（10）还包括第二密封装置（46），该第二密封装置将流体室（18）与第三和第四隔室（34）分隔开，，第二密封装置（46）具有远离第一盖子（20）的第二纵向端部。此外，过滤装置（10）包括均设置在流体室（18）处且位于第一密封装置（42）的第一纵向端部与第二密封装置（42）之间的第四流体端口（50）和第五流体端口第二密封装置（46）的第二纵向端。

28. 发明申请

WO2017064252A1 DIALYSIS SYSTEM AND METHOD INCLUDING A FLOW PATH INSULATOR 审中-公开
标题翻译：包括流动路径绝缘子的透析系统和方法
公开(公告)号：WO2017064252A1
公开(公告)日：2017-04-20
申请号：PCT/EP2016/074712
申请日：2016-10-14
申请人： GAMBRO LUNDIA AB
发明人： HOBRO, Sture , JANSSON, Olof , TORGNY, Erik , SENDELIUS, Peter , PÅLSSON, Ingemar , STÅHL, Daniel
IPC分类号： A61M1/16 , A61M1/34 , A61M1/36
CPC分类号： A61M1/16 , A61M1/34 , A61M1/3413 , A61M1/3621 , A61M1/367 , A61M2205/07 , A61M2205/15 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/70
摘要： A renal failure therapy system (10) includes: a dialyzer (102); a blood circuit (100) including a blood pump (120) in fluid communication with the dialyzer (102); a dialysis circuit (30) in fluid communication with the dialyzer (102); and at least one flow path insulator (150, 155) located in the dialysis circuit (30) or the blood circuit (100), the flow path insulator (150, 155) including a structure that separates liquid flowing within the flow path insulator (150, 155) into a plurality (e.g., two or more) of separated liquid segments (160) that create electrical isolation within the flow path insulator (150, 155).
摘要翻译：肾衰竭治疗系统（10）包括：透析器（102）;透析器包括与所述透析器（102）流体连通的血泵（120）的血液回路（100）; 与透析器（102）流体连通的透析回路（30）; 和位于所述透析回路（30）或所述血液回路（100）中的至少一个流路绝缘体（150,155），所述流路绝缘体（150,155）包括将所述流路绝缘体 150,155）分成在流动路径绝缘体（150,155）内产生电隔离的多个（例如，两个或更多个）分离的液体段（160）。

29. 发明申请

WO2013092284A1 DIALYSIS PRECURSOR COMPOSITION 审中-公开
标题翻译： DIALYSIS前身组成
公开(公告)号：WO2013092284A1
公开(公告)日：2013-06-27
申请号：PCT/EP2012/075008
申请日：2012-12-11
申请人： GAMBRO LUNDIA AB
发明人： JANSSON, Olof , GUSTAFSSON, Jens , LINDEN, Torbjörn
IPC分类号： A61K31/7004 , A61K33/00 , A61K33/06 , A61K33/14 , A61K9/00
CPC分类号： A61K33/14 , A61K9/00 , A61K31/194 , A61K31/7004 , A61K33/00 , A61K33/06 , A61M1/1654 , A61M1/287 , A61K2300/00
摘要： The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention said glucose is present as anhydrous components in said dialysis acid precursor composition and said at least one magnesium salt is present as magnesium chloride 4.5-hydrate (MgCl 2 ⋅ 4 ⋅5H 2 O).
摘要翻译：本发明涉及一种透析酸前体组合物，用于制备透析酸浓缩液，并与水，含钠浓缩物和含碳酸氢盐的浓缩液混合成即用型透析溶液。所述透析酸前体组合物由包含葡萄糖，至少一种干酸和至少一种镁盐，以及任选的钾盐和钙盐的粉末组分组成。根据本发明，所述葡萄糖以所述透析酸前体组合物中的无水组分存在，并且所述至少一种镁盐以氯化镁4.5水合物（MgCl 2 s 4 sH 2 O）存在。

30. 发明申请

WO2012126745A2 METHODS AND DEVICES FOR OPERATING AN INFUSION SYSTEM 审中-公开
标题翻译：用于操作输注系统的方法和装置
公开(公告)号：WO2012126745A2
公开(公告)日：2012-09-27
申请号：PCT/EP2012/054074
申请日：2012-03-09
申请人： GAMBRO LUNDIA AB , JANSSON, Olof , OLDE, Bo
发明人： JANSSON, Olof , OLDE, Bo
IPC分类号： A61M5/142 , A61M5/168 , A61M5/36 , A61M1/36 , A61M5/14
CPC分类号： A61M5/14216 , A61M5/16809 , A61M5/1684 , A61M5/16854 , A61M5/16859 , A61M5/36 , A61M5/365 , A61M2005/1402 , A61M2205/15 , A61M2205/3331 , A61M2205/702
摘要： An infusion system defines a fill path (4) for an infusion liquid from a source (5) to a displacement volume in a fluid chamber (8) of an infusion pump (1), and an infusion path (2) from the displacement volume to a connector (19a). The infusion pump (1) is operated to repeatedly draw infusion liquid from the source (5) into the displacement volume via the fill path (4) and push infusion liquid from the displacement volume through the connector (19a) via the infusion path (2). A controller (11) selectively effects a priming operation, by operating the infusion pump (1) to generate a priming fill stroke, in which a priming volume of the infusion liquid is drawn from the source (5) to the displacement volume, and a priming pump stroke, in which at least part of the priming volume is pushed from the displacement volume back to the source (5). The infusion system is thereby operable to be primed automatically, and proper priming may be verified by evaluating a measurement signal representative of fluid pressure in the displacement volume during either of the priming fill stroke and the priming pump stroke.
摘要翻译：输注系统限定用于输液（5）到输液泵（1）的流体室（8）中的移液量的输注液体的填充路径（4）和来自排量的输注路径（2）连接器（19a）。输液泵（1）被操作以经由填充路径（4）将来自源（5）的输注液体重复地吸入移动体积中，并且经由输注路径（2）将输注液体从置换体积通过连接器（19a）推入）。控制器（11）通过操作输液泵（1）来选择性地进行起动操作，以产生起动填充冲程，其中将输注液体的起动体积从源（5）抽取到排量体积，并且起动泵冲程，其中至少部分起动容积从排量体积推回到源（5）。输注系统由此可操作地自动启动，并且可以通过在启动填充冲程和起动泵冲程期间评估表示位移体积中的流体压力的测量信号来验证适当的起动。

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