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21. 发明申请

US20080214417A1 Lubricant for wear testing of joint replacements and associated materials 审中-公开
公开(公告)号：US20080214417A1
公开(公告)日：2008-09-04
申请号：US12069280
申请日：2008-02-07
申请人： Jan-M Brandt , Kory D. Charron , Lin Zhao , John B. Medley , Steven J. MacDonald
发明人： Jan-M Brandt , Kory D. Charron , Lin Zhao , John B. Medley , Steven J. MacDonald
IPC分类号： C10M125/24
CPC分类号： A61K35/16 , C12N9/6462 , C12Y304/21073
摘要： The present invention relates to an artificial synovial fluid composition that mimics the tribological properties of human, osteoarthritic synovial fluid (SF) for the main purpose of in vitro wear testing. There is described an artificial synovial fluid composition comprising: a) a mammalian serum having i) a total protein concentration of from about 10 to about 45 g/L; ii) an albumin fraction of from about 55% to about 80% w/w %; iii) an α-1 globulin fraction of from about 3% to about 6% w/w %; iv) an α-2 globulin fraction of from about 5% to about 10% w/w %; v) a β-globulin fraction of from about 3% to about 20% w/w %; vi) a γ-globulin fraction of from about 5% to about 20% w/w %; vii) a calcium (Ca) concentration of from about 0.1 mmol/L to about 3 mmol/L; viii) a magnesium (Mg) concentration of from about 0.05 mmol/L to about 0.8 mmol/L; ix) an inorganic phosphate (P) concentration of from about 0.1 mmol/L to about 1.5 mmol/L; x) an iron (Fe) concentration of from about 0.001 mmol/L to about 0.1 mmol/L; xi) a peptide concentration at a 2,000 Da molecular weight cut-off of from about 0.005 g/L to about 10 g/L; xii) a maximal transition midpoint temperature, Tm-cp-max, of from about 330 K to about 350 K at a concentration molality of from about 0.005 to about 0.15 mmol/L measured at a scan rate of from about 20 K/hour to about 100 K/hour; xiii) a total enthalpy change, ΔH, of from about 650 kJ mol−1 to about 1200 kJ mol−1 at a set concentration molality of 0.05 mmol/l measured at a scan rate of 60 K/hour; xiv) a total entropy change, ΔS, of from about 1.5 kJ mol−1 K−1 to about 4 kJ mol−1 K−1 at a concentration molality of from about 0.005 mmol/l to about 0.15 mmol/l and a scan rate from about 20 K/hour to 100 K/hour; wherein the ratio of albumin to total globulin (α-1 globulin+α-2 globulin+β-globulin+γ-globulin fractions) in solution is from about 1.5 to about 3; b) a buffer for maintaining a solution osmolality of from about 200 mmol/kg to about 400 mmol/kg; c) hyaluronic acid (HA) at a concentration of from about 0.1 g/L to about 6 g/L; d) hyaluronic acid (HA) with a molecular weight of from 1 MDa to 4 MDa; and e) a pH level of about 7 to about 8.

22. 发明申请

US20080163659A1 Roll Profile for Both Shape Control and Free Ruled Rolling 有权
标题翻译：两种形状控制和自由滚动滚动轮廓
公开(公告)号：US20080163659A1
公开(公告)日：2008-07-10
申请号：US11909263
申请日：2006-03-24
申请人： Haodong Huang , Xianlin Chen , Anrui He , Lin Zhao , Xiaochun Sha , Xu Yang , Xin Chen , Yanqiang Xu , Pusheng Ma , Xiaobo Guo , Haoran Dong , Shengtian Wu
发明人： Haodong Huang , Xianlin Chen , Anrui He , Lin Zhao , Xiaochun Sha , Xu Yang , Xin Chen , Yanqiang Xu , Pusheng Ma , Xiaobo Guo , Haoran Dong , Shengtian Wu
IPC分类号： B21B37/28
CPC分类号： B21B27/021 , B21B13/142 , B21B37/40 , B21B2027/022 , B21B2267/18 , B21B2269/14
摘要： Disclosed herein is a roll profile for work rolls for both shape control and free ruled rolling. Each of the work rolls has a tapered end. Providing starting point of the tapered end of the rolls being origin of coordinates, the curve of respective tapered end is a quartic curve represented by a formula y(x)=a0+a1x+a2x2+a3x3+a4x4, xε[0,Le], y(x)ε[0,He]. Because the transition between the tapered end and the roll body is smooth, asymmetric deformation due to the difference between abrasion of the upper and lower rolls is eliminated, which reducing wedged shape of strip and reducing unstable rolling due to asymmetrical strip stresses caused by the axial shifting of the roll. Further, as the axial shifting of the work roll is represented by Shift=B/2+Le−Se−Lw/2 so that box shaped abrasion of conventional roll is eliminated and closed type abrasion of conventional roll is changed into open type abrasion, which averaging the abrasion of the rolls, eliminating “cat ear” hole, achieving flat roll type rolling, and fulfilling the equipment of free ruled rolling.
摘要翻译：本文公开了用于形状控制和自由滚动的工作辊的辊轮廓。每个工作辊都有一个锥形端。提供辊的锥形端的起点是坐标的原点，各个锥形端的曲线是由公式y（x）= a 0 0 + a 1表示的四次曲线， / SUB> x + a 2 4，x 4，xepsilon [0，Le]，y（x）ε[0，He]。由于锥形端部与辊体之间的过渡是平滑的，因此消除了由于上下辊的磨损之间的差异导致的不对称变形，这减小了带状的楔形形状，并且由于由轴向引起的不对称带状应力而减少不稳定的轧制卷的移动。此外，随着工作辊的轴向移动由Shift = B / 2 + Le-Se-Lw / 2表示，从而消除了常规辊的箱形磨损，并将常规辊的封闭式磨损变为开式磨损，平均轧辊磨损，消除“猫耳”孔，实现平辊轧制，实现自由轧制设备。

23. 发明授权

US08949178B2 Method and system for efficient data synchronization 有权
标题翻译：高效数据同步的方法和系统
公开(公告)号：US08949178B2
公开(公告)日：2015-02-03
申请号：US12653091
申请日：2009-12-08
申请人： Lin Zhao , Hai Wang , Qing Zhang , Yina Zhang
发明人： Lin Zhao , Hai Wang , Qing Zhang , Yina Zhang
IPC分类号： G06F17/00 , G06F17/30 , G06F7/00
CPC分类号： G06F17/30174 , G06F11/1658 , G06F17/30348 , G06F17/3038 , G06F17/30383 , G06F17/3056 , G06F17/30592
摘要： Data synchronization includes establishing a plurality of target data tables based on a source data table in which data to be synchronized is stored, determining a current target data table from the plurality of target data tables, synchronizing the source data table and the current target data table, and directing an application server to access the current target data table upon successful completion of synchronization.
摘要翻译：数据同步包括基于存储有待同步数据的源数据表建立多个目标数据表，从多个目标数据表确定当前目标数据表，同步源数据表和当前目标数据表并且在成功完成同步时指示应用服务器访问当前目标数据表。

24. 发明申请

US20070167454A1 Methods for treating hypertension 审中-公开
标题翻译：治疗高血压的方法
公开(公告)号：US20070167454A1
公开(公告)日：2007-07-19
申请号：US11497608
申请日：2006-08-02
申请人： Christopher Lademacher , Lin Zhao , Nancy Joseph-Ridge , Richard Johnson
发明人： Christopher Lademacher , Lin Zhao , Nancy Joseph-Ridge , Richard Johnson
IPC分类号： A61K31/53 , A61K31/426 , A61K31/4196 , A61K31/415
CPC分类号： C07D277/56 , A61K31/00 , A61K31/415 , A61K31/4196 , A61K31/426 , A61K31/53 , A61K45/06
摘要： The present invention relates to methods of treating subjects suffering from pre-hypertension or hypertension by administering to a subject in need of treatment thereof a therapeutically effective amount of at least one xanthine oxidoreductase inhibiting compound or salt thereof.
摘要翻译：本发明涉及通过向需要治疗的受试者施用治疗有效量的至少一种黄嘌呤氧化还原酶抑制化合物或其盐来治疗患有高血压前期或高血压的受试者的方法。

25. 发明授权

US11783179B2 System and method for domain- and language-independent definition extraction using deep neural networks 有权
公开(公告)号：US11783179B2
公开(公告)日：2023-10-10
申请号：US16958892
申请日：2018-12-27
申请人： Robert Bosch GmbH , Lin Zhao , Kui Xu , Zhe Feng
发明人： Yifan He , Lin Zhao , Kui Xu , Zhe Feng
IPC分类号： G06F17/00 , G06N3/08 , G06F40/237 , G06N3/042 , G06N3/044 , G06N3/045 , G06F16/36 , G06F40/247 , G06F40/279
CPC分类号： G06N3/08 , G06F16/367 , G06F40/237 , G06N3/042 , G06N3/044 , G06N3/045 , G06F40/247 , G06F40/279
摘要： A method of automatically generating a terminology definition knowledge base (KB) includes mapping each word in a word sequence to a real value dense vector using dense vector representations. The word sequence is then processed using a Convolutional Neural Network (CNN) model to identify whether the word sequence includes a terminology definition and to label the word sequence with a label indicating whether a terminology definition exists within the word sequence. The word sequence is then processed using a Conditional Random Field (CRF) model to identify boundaries of the terminology definition in the word sequence. The terminology definition is then extracted and added to the terminology definition KB.

26. 发明申请

US20140020439A1 FLIP KEY FOR AN AUTOMOTIVE VEHICLE WITH ENHANCED RESISTANCE TO FORCES EXERTED ONTO AN INSERT OF SUCH FLIP KEY 有权
标题翻译：用于具有增强的抵抗力的汽车驾驶员钥匙
公开(公告)号：US20140020439A1
公开(公告)日：2014-01-23
申请号：US13992061
申请日：2011-11-14
申请人： Lin Zhao , Zdenek Mrazek , Victor Villagrasa
发明人： Lin Zhao , Zdenek Mrazek , Victor Villagrasa
IPC分类号： E05B19/04
CPC分类号： E05B19/043 , Y10T70/7808 , Y10T70/7876 , Y10T70/8676
摘要： The invention relates to an automotive vehicule key in which a button (30) maintains by means of two legs (32, 33) a rotatable bearing (20) and a housing (40) fixed in mutual rotation at least in a situation where the key is in open position, the rotatable bearing (20) presenting an elongated shape so that the rotatable bearing (20) presents at least a longer dimension (a) and at least a shorter dimension (b) transversal to the said at least one longer dimension (a), wherein one leg (33) of the said at least two legs (32, 33) extends sensibly in the direction of the longer dimension (a) and the other leg (32) of the at least two legs (32,33) extends sensibly in the direction of the shorter transversal dimension (b), and the leg (33) extending in the direction of the longer dimension (a) is longer along said longer direction (a) than the leg (32) which extends in the direction of the transversal dimension (b).
摘要翻译：本发明涉及一种汽车键盘，其中按钮（30）通过两个支腿（32,33）保持可旋转的轴承（20）和至少在键的情况下相互固定的壳体（40）保持处于打开位置，所述可旋转轴承（20）具有细长形状，使得所述可旋转轴承（20）至少具有比所述至少一个较长尺寸横向的较长尺寸（a）和至少较短尺寸（b）（a），其中所述至少两个腿部（32,33）的一个腿部（33）在较长尺寸（a）的方向和所述至少两个腿部（32,33）的另一个腿部（32）沿较短横向尺寸（b）的方向明显地延伸，并且沿着较长尺寸（a）的方向延伸的腿部（33）沿着所述较长方向（a）比延伸的腿部（32）更长沿横向方向（b）。

27. 发明申请

US20120266699A1 LUBRICANT FOR WEAR TESTING OF JOINT REPLACEMENTS AND ASSOCIATED MATERIALS 审中-公开
标题翻译：润滑剂用于联接更换和相关材料的磨损测试
公开(公告)号：US20120266699A1
公开(公告)日：2012-10-25
申请号：US13274088
申请日：2011-10-14
申请人： Jan-M. Brandt , Kory D.J. Charron , Lin Zhao , John B. Medley , Steven J. MacDonald
发明人： Jan-M. Brandt , Kory D.J. Charron , Lin Zhao , John B. Medley , Steven J. MacDonald
IPC分类号： C10M141/10 , G01N33/00
CPC分类号： A61K35/16 , C12N9/6462 , C12Y304/21073
摘要： The present invention relates to an artificial synovial fluid composition that mimics the tribological and biochemical properties of human, osteoarthritic synovial fluid for in vitro testing of implantable materials. The artificial synovial fluid comprises new-born calf serum or alpha-calf serum (iron-free or iron-supplemented) that contains a specific total protein concentration, specific protein constituent fractions (albumin, α-1 globulin, α-2 globulin, β-globulin, and γ-globulin), specific trace element concentrations (Ca, Mg, inorganic P, and Fe), and a specific low-molecular weight peptide concentration important for in vitro testing of implantable materials. In addition, the artificial synovial fluid contains a hyaluronic acid concentration and level of osmolality (preferably using phosphate buffered-saline solution) to mimic the thermal stability (transition mid-point temperature, enthalpy, and entropy) and pH level as measured clinically.
摘要翻译：本发明涉及人造滑液组合物，其模拟人骨关节炎滑液的摩擦学和生物化学性质，用于体外测试可植入材料。人造滑液包含含有特定总蛋白浓度的新生小牛血清或α-小牛血清（无铁或铁补充），特异性蛋白质组分（白蛋白，α-1球蛋白，α-2球蛋白，bgr ; - 球蛋白和γ-球蛋白），特异性微量元素浓度（Ca，Mg，无机P和Fe）以及对可植入材料的体外测试重要的特异性低分子量肽浓度。此外，人造滑液含有透明质酸浓度和渗透压水平（优选使用磷酸盐缓冲盐水溶液）以模拟临床测定的热稳定性（转变中点温度，焓和熵）和pH水平。

28. 发明申请

US20100145910A1 Method and system for efficient data synchronization 有权
标题翻译：高效数据同步的方法和系统
公开(公告)号：US20100145910A1
公开(公告)日：2010-06-10
申请号：US12653091
申请日：2009-12-08
申请人： Lin Zhao , Hai Wang , Qing Zhang , Yina Zhang
发明人： Lin Zhao , Hai Wang , Qing Zhang , Yina Zhang
IPC分类号： G06F17/00
CPC分类号： G06F17/30174 , G06F11/1658 , G06F17/30348 , G06F17/3038 , G06F17/30383 , G06F17/3056 , G06F17/30592
摘要： Data synchronization includes establishing a plurality of target data tables based on a source data table in which data to be synchronized is stored, determining a current target data table from the plurality of target data tables, synchronizing the source data table and the current target data table, and directing an application server to access the current target data table upon successful completion of synchronization.
摘要翻译：数据同步包括基于存储有待同步数据的源数据表建立多个目标数据表，从多个目标数据表确定当前目标数据表，同步源数据表和当前目标数据表并且在成功完成同步时指示应用服务器访问当前目标数据表。

29. 发明申请

US20090244095A1 RUN-TIME LABEL CACHE FOR EFFICIENT MAP LABELING 审中-公开
标题翻译：运行时标签缓存高效地图标签
公开(公告)号：US20090244095A1
公开(公告)日：2009-10-01
申请号：US12060337
申请日：2008-04-01
申请人： Gordon Gregory Bowman , Lin Zhao
发明人： Gordon Gregory Bowman , Lin Zhao
IPC分类号： G09G5/00
CPC分类号： G06F16/957 , G09G2370/16
摘要： A wireless communications device has a processor coupled to a memory for reconstructing a map feature from discrete sets of map data that provide redundant labels for the map feature to thereby generate a reconstructed map feature having only a single instance of the label, wherein the memory stores a run-time label cache for caching the reconstructed map feature and the label associated with the reconstructed map feature for reuse in rendering a subsequent map that also includes the reconstructed map feature. As new map data is received for each subsequent map, for example when the map is panned, the reconstructed map feature is modified by trimming off portions of the map feature that have moved outside the area of interest and by stitching to the reconstructed map feature portions of the map feature that have moved into the area of interest.
摘要翻译：无线通信设备具有耦合到存储器的处理器，用于从地图数据的离散集合重建地图特征，为地图特征提供冗余标签，从而生成仅具有标签的单个实例的重建地图特征，其中存储器存储用于缓存重建的地图特征的运行时标签高速缓存和与重构的地图特征相关联的标签，用于再现还包括重建的地图特征的后续地图。当对于每个后续的地图接收到新的地图数据时，例如当地图被平移时，重建的地图特征是通过修剪已经移动到感兴趣区域之外的地图特征的部分并且通过缝合到重建的地图特征部分的地图特征已经移动到感兴趣的区域。

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