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21. 发明申请

US20080255068A1 Chemical Compound and Its Use 失效
标题翻译：化合物及其用途
公开(公告)号：US20080255068A1
公开(公告)日：2008-10-16
申请号：US11793482
申请日：2005-12-15
申请人： Hilmar Bischoff , Heike Gielen-Haertwig , Volkhart Li , Carsten Schmeck , Michael Thutewohl , Alexandros Vakalopoulos , Olaf Weber , Martina Wuttke
发明人： Hilmar Bischoff , Heike Gielen-Haertwig , Volkhart Li , Carsten Schmeck , Michael Thutewohl , Alexandros Vakalopoulos , Olaf Weber , Martina Wuttke
IPC分类号： A61K31/695 , A61K31/47 , A61P3/04 , A61P25/28 , C07D215/20
CPC分类号： C07D215/20
摘要： The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
摘要翻译：本申请涉及一种新的四氢喹啉衍生物，其制备方法，其单独使用或组合用于治疗和/或预防疾病及其用于制备药物的用途，特别是作为胆固醇酯的抑制剂转运蛋白（CETP）用于治疗和/或预防心血管疾病，特别是低脂蛋白血症，血脂异常，高甘油三酯血症，高脂血症，高胆固醇血症和动脉硬化。

22. 发明授权

US06640794B2 Intake system for an internal combustion engine with a membrane preferentially permeable to oxygen molecules 有权
标题翻译：具有优先渗透氧分子的膜的内燃机进气系统
公开(公告)号：US06640794B2
公开(公告)日：2003-11-04
申请号：US10206862
申请日：2002-07-29
申请人： Olaf Weber
发明人： Olaf Weber
IPC分类号： F02B2300
CPC分类号： F02M35/10019 , B01D53/22 , B01D63/00 , B01D63/02 , B01D2313/23 , F02M25/12 , F02M35/02 , F02M35/10301 , F02M35/1038 , F02M35/10393 , F02M35/161 , Y02T10/121
摘要： An intake system (13) for an internal combustion engine (12) which includes a housing (15a) with a filter insert (16) and a membrane (22) for separating nitrogen and enriching the combustion air with oxygen. The membrane is integrated into the filter housing so as to save construction space and provide a lower cost system. The membrane (22) can alternatively be arranged on the clean air side of the air filter insert (16) to prevent the membrane from being soiled and to improve the functional reliability of the oxygen enrichment. Alternatively, instead of arranging the membrane (22) on the clean side of the filter insert (16), the membrane can be protected from being soiled by using a cover (23).
摘要翻译：一种用于内燃机（12）的进气系统（13），其包括具有过滤器插件（16）的壳体（15a）和用于分离氮气并使燃烧空气与氧气富集的膜（22）。膜被整合到过滤器壳体中，以节省建筑空间并提供较低成本的系统。可选地，膜（22）可以布置在空气过滤器插入件（16）的清洁空气侧，以防止膜被污染并提高氧气富集的功能可靠性。或者，代替将膜（22）布置在过滤器插入件（16）的清洁侧上，可以通过使用盖（23）来防止膜被污染。

23. 发明授权

US06224531B1 Rotor for a free jet centrifuge having an internal guiding element 有权
标题翻译：转子用于具有内部引导元件的自由喷射式离心机
公开(公告)号：US06224531B1
公开(公告)日：2001-05-01
申请号：US09403100
申请日：2000-03-06
申请人： Peter Frehland , Helmut Fischer , Martin Weindorf , Olaf Weber
发明人： Peter Frehland , Helmut Fischer , Martin Weindorf , Olaf Weber
IPC分类号： B04B104
CPC分类号： B04B5/005 , F01M2001/1035 , F01M2013/0422
摘要： A rotor (1) designed to be installed in the housing (16) of a free jet centrifuge, the rotor being provided with at least one inlet (3) and at least one outlet (4), which outlet is configured as a nozzle which is oriented at least substantially tangentially to the axis of rotation (13) of the rotor. The rotor is provided with receptacles for bearings for rotatably mounting the rotor, and the rotor having at least one guide element (7) which extends from an inner wall (38) to an outer wall (39) of a rotor interior space (8). At least the rotor shell (11) is made of synthetic resin material. Owing to its form, the synthetic resin centrifuge rotor can be made up of a reduced number of parts. The rotor may be composed of two elements, a base (10) and a shell (11), connected together either by a snap connection or by welding, such as vibration welding. An oil centrifuge fitted with such a rotor is particularly suitable for cleaning lubricating oil used in an internal combustion engine.
摘要翻译：一种设计成安装在自由射流离心机的壳体（16）中的转子（1），该转子设置有至少一个入口（3）和至少一个出口（4），该出口被配置为喷嘴至少基本上相对于转子的旋转轴线（13）切向。该转子设置有用于可旋转地安装转子的轴承的插座，并且转子具有至少一个从转子内部空间（8）的内壁（38）延伸到外壁（39）的导向元件（7）。至少转子壳体（11）由合成树脂材料制成。由于其形式，合成树脂离心机转子可以由减少数量的部件组成。转子可以由两个元件组成，即基座（10）和外壳（11），通过卡扣连接或通过焊接（例如振动焊接）连接在一起。装有这种转子的油离心机特别适用于清洁内燃机中使用的润滑油。

24. 发明授权

US6094909A Secondary air system for an internal combustion engine 有权
标题翻译：内燃机二次空气系统
公开(公告)号：US6094909A
公开(公告)日：2000-08-01
申请号：US202836
申请日：1998-12-15
申请人： Olaf Weber , Holger Paffrath
发明人： Olaf Weber , Holger Paffrath
IPC分类号： F01N3/30 , F01N3/32 , F02D9/02 , F02M25/07 , F01N5/04
CPC分类号： F02D9/02 , F01N3/303 , F01N3/32 , F01N3/323 , F02M26/34 , F02D2009/0283 , Y02T10/20
摘要： A secondary air system for an internal combustion engine (32), including at least one line (14) through which air is blown into the exhaust pipe of the engine, a pump (26) and a drive (27) for the pump (26). In addition an air-feed line (13) is provided through which the secondary air is supplied to the pump (26). The power necessary to drive the pump is provided by the engine (32).
摘要翻译： PCT No.PCT / EP97 / 01665 Sec。 371 1998年12月15日第 102（e）日期1998年12月15日PCT 1997年4月3日PCT PCT。出版物WO97 / 38212 PCT 日本1997年10月16日用于内燃机（32）的二次空气系统包括至少一条管线（14），空气吹入发动机的排气管中，泵（26）和驱动器（27）用于泵（26）。此外，提供空气供给管线（13），二次空气通过该供气管线供应到泵（26）。驱动泵所需的动力由发动机（32）提供。

25. 发明授权

US08529675B2 Air filter system 有权
标题翻译：空气过滤系统
公开(公告)号：US08529675B2
公开(公告)日：2013-09-10
申请号：US11280307
申请日：2005-11-17
申请人： Michael Durst , Nikolaus Moser , Andreas Pelz , Olaf Weber
发明人： Michael Durst , Nikolaus Moser , Andreas Pelz , Olaf Weber
IPC分类号： B01D59/26
CPC分类号： B01D46/2422 , B01D46/0036 , B01D2253/102
摘要： An air filter system with an air filter element having an inflow and an outflow face and comprising alternating flat and pleated layers, which are configured to form channels. The channels are alternately sealed in inflow and outflow direction, such that the medium to be filtered must pass through one of the layers as it flows from the inflow face through the filter to the outflow face. An adsorber element made of an activated carbon coated honeycomb structure is disposed adjacent the air filter element.
摘要翻译：一种具有空气过滤器元件的空气过滤器系统，其具有流入和流出面，并且包括交替的平坦和褶皱层，其被配置为形成通道。通道在流入和流出方向上交替地密封，使得待流过的介质当从流入面通过过滤器流到流出面时必须通过其中一层。由活性炭涂覆的蜂窝结构体制成的吸附元件邻近空气过滤器元件设置。

26. 发明授权

US08343478B2 Parapoxviruses in combination with other antiviral agents for the treatment of viral diseases 有权
标题翻译：副抗病毒药物与其他抗病毒药物联合用于治疗病毒性疾病
公开(公告)号：US08343478B2
公开(公告)日：2013-01-01
申请号：US11652937
申请日：2007-01-11
申请人： Daniela Paulsen , Helga Ruebsamen-Schaeff , Amar Kureishi , Gerhard Hunsmann , Christiane Stahl-Hennig , Andreas Meyerhans , Alexandra Schuetz , Olaf Weber
发明人： Daniela Paulsen , Helga Ruebsamen-Schaeff , Amar Kureishi , Gerhard Hunsmann , Christiane Stahl-Hennig , Andreas Meyerhans , Alexandra Schuetz , Olaf Weber
IPC分类号： A61K39/155 , A61K31/711 , A61K38/00
CPC分类号： A61K45/06 , A61K31/70 , A61K35/76 , C12N2710/24232 , C12N2740/15011 , C12N2740/16011 , A61K2300/00
摘要： The present invention relates to the use of Parapoxviruses in combination with other agents for the treatment of viral diseases, and in particular HIV infections and AIDS. The invention also relates to methods for producing medicaments based on combinations of Parapoxviruses and other antiviral agents, and to such medicaments. In particular, the invention relates to the use of Parapoxviruses in combination with agents of the kind used for antiretroviral therapy and highly active antiretroviral therapy (HAART).
摘要翻译：本发明涉及与其它药剂组合用于治疗病毒性疾病，特别是HIV感染和AIDS的副作用病毒的用途。本发明还涉及基于对痘病毒和其它抗病毒剂的组合制备药物的方法以及这些药物。特别地，本发明涉及副作用病毒与用于抗逆转录病毒治疗和高活性抗逆转录病毒治疗（HAART）的药物的组合的使用。

27. 发明申请

US20110061625A1 EXHAUST THROTTLE-EGR VALVE MODULE FOR A DIESEL ENGINE 审中-公开
标题翻译：用于柴油发动机的排气节流阀模块
公开(公告)号：US20110061625A1
公开(公告)日：2011-03-17
申请号：US12620543
申请日：2009-11-17
申请人： Volker Joergl , Timm Kiener , Olaf Weber , Bruce Thorpe
发明人： Volker Joergl , Timm Kiener , Olaf Weber , Bruce Thorpe
IPC分类号： F01L7/00
CPC分类号： F02M26/16 , F02B29/0406 , F02M26/06 , F02M26/10 , F02M26/15 , F02M26/23 , F02M26/35 , F02M26/53 , F02M26/54 , F02M26/71 , Y10T137/86855 , Y10T137/86871
摘要： A valve assembly for use in an air management assembly having an engine, an exhaust side, and an intake side, where the valve assembly provides a housing, a plurality of openings in the housing, a valve in the housing, and an actuator operably connected to the valve. The housing is in fluid communication with the exhaust side and the intake side. The plurality of openings in the housing form at least one inlet and at least one outlet in the housing. The valve moves with respect to the plurality of openings.
摘要翻译：一种用于具有发动机，排气侧和进气侧的空气管理组件的阀组件，其中阀组件提供壳体，壳体中的多个开口，壳体中的阀和可操作地连接的致动器到阀门。外壳与排气侧和进气侧流体连通。壳体中的多个开口形成壳体中的至少一个入口和至少一个出口。阀相对于多个开口移动。

28. 发明申请

US20100216789A1 RHO-KINASE INHIBITORS 审中-公开
标题翻译： RHO-激酶抑制剂
公开(公告)号：US20100216789A1
公开(公告)日：2010-08-26
申请号：US12688428
申请日：2010-01-15
申请人： Dhanapalan NAGARATHNAM , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
发明人： Dhanapalan NAGARATHNAM , Uday Khire , Davoud Asgari , Jianxing Shao , Xiao-Gao Liu , Chunguang Wang , Barry Hart , Olaf Weber , Mark Lynch , Lei Zhang , Lei Wang
IPC分类号： A61K31/519 , C07D495/04 , A61K31/5377 , A61K31/53 , C07D513/04 , A61P9/12 , A61P9/10 , A61P15/10
CPC分类号： C07D471/04 , C07D491/04 , C07D495/04
摘要： Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.
摘要翻译：公开了其化合物及其衍生物，其合成及其作为Rho-激酶抑制剂的用途。本发明的这些化合物可用于抑制肿瘤生长，治疗勃起功能障碍，以及治疗由Rho-激酶（例如冠心病）介导的其它适应症。

29. 发明授权

US07757679B2 Integrated charge air and EGR valve 有权
标题翻译：集成增压空气和EGR阀
公开(公告)号：US07757679B2
公开(公告)日：2010-07-20
申请号：US12224414
申请日：2007-03-22
申请人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
发明人： Volker Joergl , Timm Kiener , Olaf Weber , Robert S. Czarnowski
IPC分类号： F02B47/08
CPC分类号： F02B29/0418 , F02D2009/0276 , F02M26/05 , F02M26/06 , F02M26/07 , F02M26/15 , F02M26/16 , F02M26/24 , F02M26/26 , F02M26/64 , Y02T10/146
摘要： An engine assembly (10) comprising an engine, a plurality of coolers, a plurality of bypasses, and at least one actuator (32). The engine has an exhaust manifold and an intake manifold. The gaseous fluid exiting the exhaust manifold is recirculated to the intake manifold. The exhaust gas passes through either an air cooler or a bypass. At least one actuator is operably connected to the plurality of bypasses. The bypasses have a valve (28, 30) which is actuated to control the flow of the gaseous fluid through the bypass as both the bypass and the cooler. Therefore, when a single actuator is used to control the valves in both bypasses, the valves in the bypasses have the same relationship with the inlets so that a single actuator movement will control both valves in the same manner.
摘要翻译：包括发动机，多个冷却器，多个旁路以及至少一个致动器（32）的发动机组件（10）。发动机具有排气歧管和进气歧管。离开排气歧管的气体流体再循环到进气歧管。废气通过空气冷却器或旁路。至少一个致动器可操作地连接到多个旁路。旁路具有阀（28,30），其被致动以控制气体流体通过旁路作为旁路和冷却器的流动。因此，当使用单个致动器来控制两个旁路中的阀时，旁路中的阀与入口具有相同的关系，使得单个致动器运动将以相同的方式控制两个阀。

30. 发明申请

US20100129321A1 DIARYL UREA FOR TREATING VIRUS INFECTIONS 审中-公开
标题翻译：用于治疗病毒感染的二尿法
公开(公告)号：US20100129321A1
公开(公告)日：2010-05-27
申请号：US12086454
申请日：2006-12-06
申请人： Olaf Weber , Bernd Riedl
发明人： Olaf Weber , Bernd Riedl
IPC分类号： A61K31/44 , C07D213/81 , A61K31/513 , A61K31/662 , A61K38/16 , A61K31/551 , A61K31/4745 , A61K31/52 , A61K31/522 , A61K31/675 , A61K31/4439 , A61K31/536 , A61K31/472 , A61K31/4725 , A61K31/496 , A61K31/7072 , A61K31/7068 , A61K31/708 , A61K35/76 , A61K36/71 , A61K38/14 , A61K38/21 , A61K31/56 , A61P31/12
CPC分类号： A61K31/44 , A61K31/496 , A61K45/06 , A61K2300/00
摘要： The present invention relates to pharmaceutical compositions for treating virus infections and/or diseases caused thereby comprising 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide optionally combined with at least one additional therapeutic agent.
摘要翻译：本发明涉及用于治疗由此引起的病毒感染和/或疾病的药物组合物，其包含4 {4- [3-（4-氯-3-三氟甲基苯基） - 脲基] -3-氟苯氧基} - 吡啶-2-甲酸甲基酰胺任选地与至少一种另外的治疗剂组合。

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