专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

US20070299400A1 Infusion device with dome pump 审中-公开
标题翻译：输液装置带圆顶泵
公开(公告)号：US20070299400A1
公开(公告)日：2007-12-27
申请号：US11705816
申请日：2007-02-12
申请人： Clifton Alferness , John Adams , Daniel Hawkins
发明人： Clifton Alferness , John Adams , Daniel Hawkins
IPC分类号： A61M5/142
CPC分类号： A61M5/1452 , A61M5/1408 , A61M5/14248 , A61M5/14526 , A61M5/1454 , A61M5/16881 , A61M2005/1405 , A61M2005/1426 , A61M2005/1585 , A61M2005/1587 , A61M2025/0266
摘要： A disposable infusion device comprises a base arranged to adhere to a patient's skin, a cannula arranged to extend from the base to beneath the patient's skin to deliver a liquid medicament to the patient, and a source arranged to provide the cannula with a liquid medicament. The source includes a pump arranged to be driven by the patient that pumps the liquid medicament to the cannula.
摘要翻译：一次性输注装置包括布置成粘附到患者皮肤的基部，套管布置成从基部延伸到患者皮肤下方以将液体药物递送到患者，以及布置成为套管提供液体药物的源。源包括被布置成由患者驱动的泵，其将液体药物泵送到套管。

22. 发明申请

US20070260276A1 Transesophageal gastric reduction device, system and method 审中-公开
标题翻译：经食道胃减压装置，系统及方法
公开(公告)号：US20070260276A1
公开(公告)日：2007-11-08
申请号：US11823998
申请日：2007-06-29
申请人： Stefan Kraemer , John Adams
发明人： Stefan Kraemer , John Adams
IPC分类号： A61M29/00
CPC分类号： A61F5/0086 , A61B17/122 , A61B17/1285 , A61B2017/00818 , A61B2017/308 , A61F2/91
摘要： A gastric reduction system and method provides for transesophageal formation of a gastric reduction pouch of the stomach. The system includes an expandable structure which may be placed in a stomach and expanded to occupy a fractional volume of the stomach. An evacuator is then fed through the expandable structure and utilized to deflate the stomach and draw the stomach to and around the expandable structure to form the gastric reduction pouch. A self-deploying fastener is then deployed to maintain the gastric reduction pouch.
摘要翻译：胃减压系统和方法提供胃的胃减压袋的经食道形成。该系统包括可扩张结构，其可以放置在胃中并且膨胀以占据胃的分数体积。然后将排气器通过可膨胀结构进料，并用于使胃胀开，并将胃抽吸到可膨胀结构周围并围绕可膨胀结构并形成胃减压袋。然后展开自展展紧固件以维持胃减压袋。

23. 发明申请

US20070232519A1 Human G protein-coupled receptor and modulators thereof for the treatment of cardiovascualr disorders 审中-公开
标题翻译：人G蛋白偶联受体及其调节剂用于治疗心血管疾病
公开(公告)号：US20070232519A1
公开(公告)日：2007-10-04
申请号：US11604187
申请日：2006-11-22
申请人： John Adams , Daniel Connolly
发明人： John Adams , Daniel Connolly
IPC分类号： A61K48/00 , A01H5/00 , C12N5/06 , G01N33/53
CPC分类号： C07K14/705 , A01K2217/05 , A01K2217/075 , A01K2227/105 , A01K2227/108 , A01K2267/0375 , G01N2333/726 , G01N2500/10 , G01N2800/325
摘要： The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In some embodiments, the GPCR is mammalian, preferably human. In some embodiments, the GPCR is expressed endogenously by cardiomyocytes. In some embodiments, the GPCR is coupled to Gq. In some embodiments, the GPCR increases the intracellular level of inositol 1,4,5-triphosphate (IP3). In some embodiments, a modulator of the GPCR is a modulator of cardiomyocyte hypertrophy. The present invention further relates to methods of using a modulator of the GPCR. Preferred modulators are inverse agonists and antagonists. Inverse agonists and antagonists of the invention are useful as therapeutic agents for the prevention or treatment of heart disease, including hypertrophic cardiomyopathy and congestive heart failure, in particular hypertrophic cardiomyopathy resulting from post-myocardial infarction remodeling, cardiac valve disease, sustained cardiac afterload, myocarditis, and familial hypertrophic cardiomyopathy.
摘要翻译：本发明涉及鉴定候选化合物是G蛋白偶联受体（GPCR）的调节剂的方法。在一些实施方案中，GPCR是哺乳动物，优选人。在一些实施方案中，GPCR由心肌细胞内源性表达。在一些实施例中，GPCR耦合到Gq。在一些实施方案中，GPCR增加1,4,5-三磷酸肌醇（IP3）的细胞内水平。在一些实施方案中，GPCR的调节剂是心肌细胞肥大的调节剂。本发明还涉及使用GPCR调制器的方法。优选的调节剂是反向激动剂和拮抗剂。本发明的反向激动剂和拮抗剂可用作预防或治疗心脏病，包括肥厚性心肌病和充血性心力衰竭的治疗剂，特别是由心肌梗死后重建，心脏瓣膜疾病，持续的心脏后负荷，心肌炎引起的肥大性心肌病，和家族性肥厚型心肌病。

24. 发明申请

US20070167961A1 Transoral endoscopic gastroesophageal flap valve restoration device, assembly, system and method 审中-公开
标题翻译：经内镜胃食管瓣瓣修复装置，组装，系统及方法
公开(公告)号：US20070167961A1
公开(公告)日：2007-07-19
申请号：US11716299
申请日：2007-03-09
申请人： Stefan Kraemer , John Adams , Stephen Vincent
发明人： Stefan Kraemer , John Adams , Stephen Vincent
IPC分类号： A61B17/08
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0644 , A61B17/07207 , A61B2017/003 , A61B2017/00827 , A61B2017/00867 , A61B2017/07214 , A61B2017/2905 , A61B2017/2926 , A61B2017/306
摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.
摘要翻译：本发明提供了一种用于胃食管瓣瓣的经口内镜恢复的装置，组装和方法。本发明还提供了一种用于组织固定的自动转向和自闭合组织固定装置，以及用于夹紧和操纵组织的起搏装置。所述修复装置包括纵向构件，所述纵向构件设置成横向放置在胃中，承载在所述纵向构件上的组织整形器，其使胃组织呈现与胃食管瓣相关的形状;以及组织固定装置，其将所述成形胃部组织保持在形状近似于胃食管皮瓣。组织整形器可以包括模具。该装置可以包括用于夹持和操纵食管组织以帮助恢复胃食管瓣的入口装置，并且可以包括组织固定装置。

25. 发明申请

US20070162058A1 Transoral endoscopic gastroesophageal flap valve restoration device, assembly, system and method 审中-公开
公开(公告)号：US20070162058A1
公开(公告)日：2007-07-12
申请号：US11716372
申请日：2007-03-09
申请人： Stefan Kraemer , John Adams , Stephen Vincent
发明人： Stefan Kraemer , John Adams , Stephen Vincent
IPC分类号： A61B17/08
CPC分类号： A61B17/068 , A61B17/00234 , A61B17/0644 , A61B17/07207 , A61B2017/003 , A61B2017/00827 , A61B2017/00867 , A61B2017/07214 , A61B2017/2905 , A61B2017/2926 , A61B2017/306
摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.

26. 发明申请

US20060245990A1 Contact structures 有权
标题翻译：接触结构
公开(公告)号：US20060245990A1
公开(公告)日：2006-11-02
申请号：US11477003
申请日：2006-06-28
申请人： Lawrence Smith , Abraham Gelbein , John Adams
发明人： Lawrence Smith , Abraham Gelbein , John Adams
IPC分类号： B01J8/02 , B01J35/02
CPC分类号： B01J19/2495 , B01D3/009 , B01J19/32 , B01J35/04 , B01J2219/00006 , B01J2219/32213 , B01J2219/32227 , B01J2219/32231 , B01J2219/32286 , B01J2219/32289 , B01J2219/32408 , B01J2219/32416 , B01J2219/32441 , B01J2219/32466 , B01J2219/32483 , B01J2219/32491 , B01J2219/3306 , B01J2219/3322 , C10G29/205 , C10G50/00
摘要： An internal static mixing system such as a disperser of mesh wire or expanded metal co-knit with a multi filament material selected from inert polymers, catalytic polymers, catalytic metals or mixtures in combination with a vertical reactor having a reaction zone and the disperser disposed in said reaction zone, particularly for carrying out paraffin alkylation using acid catalyst is disclosed. The wire mesh provides the structural integrity of the system as well as the open space required in reactors for the movement of vapors and liquids though the system. The disperser may be in sheets, bundles or bales or positioned within a frame.
摘要翻译：内部静态混合系统，例如网状丝网或多孔金属分散机，与选自惰性聚合物，催化聚合物，催化金属或混合物的多丝材料共同编织，与具有反应区和分散器的立式反应器组合所述反应区，特别是用于使用酸催化剂进行烷基烷基化的反应区。丝网提供了系统的结构完整性以及反应器中通过系统运动蒸气和液体所需的开放空间。分散器可以是片材，束或捆包或定位在框架内。

27. 发明申请

US20060227324A1 Systems and methods for detecting scattered light from a particle using illumination incident at an angle 失效
公开(公告)号：US20060227324A1
公开(公告)日：2006-10-12
申请号：US11231350
申请日：2005-09-19
申请人： Scott Bloom , John Adams , Kristina Crousore , Alex Aguirre , Michael Tutrow , Brett Spivey
发明人： Scott Bloom , John Adams , Kristina Crousore , Alex Aguirre , Michael Tutrow , Brett Spivey
IPC分类号： G01N21/49
CPC分类号： G01N15/147 , G01N15/1459 , G01N15/1475 , G01N33/18 , G01N2015/0088 , G01N2015/1497
摘要： A particle detection system uses illumination incident at an angle to detect particles in a liquid such as water. By using illumination incident at an angle, the scattered light can be measured through a range of angles that are greater than the measured range of angles produced when the illumination is incident at a normal angle, when using the same detector. For example, the light can be measured through an angle that is twice that produced with illumination incident at a normal angle.

28. 发明申请

US20060184088A1 Device and method providing arterial blood flow for perfusion of ischemic myocardium 审中-公开
标题翻译：提供动脉血流灌注缺血心肌的装置和方法
公开(公告)号：US20060184088A1
公开(公告)日：2006-08-17
申请号：US11399836
申请日：2006-04-06
申请人： Richard Van Bibber , Scott Wolf , Clifton Alferness , John Adams
发明人： Richard Van Bibber , Scott Wolf , Clifton Alferness , John Adams
IPC分类号： A61M5/00
CPC分类号： A61B17/11 , A61B17/0057 , A61B17/115 , A61B17/1155 , A61B17/32053 , A61B2017/00252 , A61B2017/00663 , A61B2017/0474 , A61B2017/1135
摘要： The present invention generally relates to methods and apparatus for use in endovascular and intraoperative procedures providing arterial blood-flow for perfusion of ischemic myocardium. Aspects of the present invention provide a conduit between a non-coronary sinus of the aorta and a coronary vein. The conduit traverses a portion of the right atrium and the coronary sinus, and is located entirely within the heart and aorta. Arterial blood flows from the aorta through the conduit and into the coronary venous circulation towards the ischemic region of the heart. All procedures described herein may be performed endovascularly, and further may be performed while the patient's heart is beating.
摘要翻译：本发明一般涉及用于血管内和术中程序的方法和装置，其提供用于灌注缺血心肌的动脉血流。本发明的方面提供主动脉的非冠状窦和冠状静脉之间的导管。导管穿过右心房和冠状窦的一部分，并且完全位于心脏和主动脉内。动脉血从主动脉通过导管流入心脏的缺血区域进入冠状静脉循环。本文描述的所有程序可以在血管内进行，并且还可以在患者的心脏跳动时进行。

29. 发明申请

US20060178578A1 Vision system to calculate a fluid volume in a container 有权
公开(公告)号：US20060178578A1
公开(公告)日：2006-08-10
申请号：US11055545
申请日：2005-02-10
申请人： Dennis Tribble , Abdul Khan , John Adams
发明人： Dennis Tribble , Abdul Khan , John Adams
IPC分类号： A61M5/00
CPC分类号： G06T7/0006 , A61M5/1684 , A61M5/31568 , A61M2205/3306 , A61M2205/3389 , B65B3/003 , B65B3/30 , G01B11/00 , G06F19/00 , G06T7/62 , G06T2207/30004
摘要： Broadly speaking the present invention is directed to a system for calculating a volume of fluid that is disposed within a container. The system includes (1) an imaging device that captures and stores an image of at least the volume of fluid in the container; (2) a background disposed behind the container so that at least the volume of fluid in the container is disposed in front of the background; and (3) a processor that performs at least one operation on the stored image to calculate the volume of the fluid within the container.

30. 发明授权

US07036201B2 Method and tool for assembling a linked suspension 有权
标题翻译：用于组装连接悬架的方法和工具
公开(公告)号：US07036201B2
公开(公告)日：2006-05-02
申请号：US10306551
申请日：2002-11-26
申请人： John Adams , Chris Vineyard , James Kelchner
发明人： John Adams , Chris Vineyard , James Kelchner
IPC分类号： B21D39/00 , B23Q3/00
CPC分类号： B60G3/00 , Y10T29/49874 , Y10T29/49895
摘要： A method for assembling a linked suspension and an assembly tool for assembling a linked suspension are provided. The method includes positioning at least one bushing within a bracket, the bushing including an outer sleeve and a tube extending therethrough, the tube being rotatable with respect to the outer sleeve of the bushing against a counter-torque; rotating the tube with respect to the outer sleeve of the bushing; and tightening the bushing to the bracket after rotating the tube with respect to the outer sleeve.
摘要翻译：提供了组装连接悬架的方法和用于组装连接悬架的组装工具。该方法包括将至少一个衬套定位在支架内，衬套包括外套筒和延伸穿过其中的管子，该套筒可相对于衬套的外套筒抵抗反扭矩旋转; 相对于衬套的外套筒旋转管; 并且在将管相对于外套筒旋转之后，将衬套拧紧到支架上。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式