专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

US20090247545A1 SUBSTITUTED OXAZOLIDINONE DERIVATIVES 审中-公开
标题翻译：取代的氧杂环丁酮衍生物
公开(公告)号：US20090247545A1
公开(公告)日：2009-10-01
申请号：US11577083
申请日：2004-12-28
申请人： Mukund Keshao Gurjar , Madhusudan Nagorao Deshmukh , Anita Mehta , Sudershan Kumar Arora , Ashok Rattan
发明人： Mukund Keshao Gurjar , Madhusudan Nagorao Deshmukh , Anita Mehta , Sudershan Kumar Arora , Ashok Rattan
IPC分类号： A61K31/496 , C07D413/10 , A61P31/04
CPC分类号： C07D263/20 , C07D413/10
摘要： The present invention provides substituted oxazolidinone derivatives, which can be used as antimicrobial agents. Compounds disclosed can be used for the treatment or prevention of a condition caused by or contributed to by bacteria, such as, inter alia, multiply-resistant Staphylococci, Streptococci, Enterococci, Bacterioides spp., Clostridium spp., Mycobacterium spp. Bacillus spp., Corynebacterium spp. Heptoslreptacoccus spp. Listeria spp., Legionella spp., Haemophilus influenza, Moraxella, Eschericia faecalis, and Eschericia coli. Processes for the preparation of disclosed compounds, pharmaceutical compositions thereof, and method of treating microbial infection are provided.
摘要翻译：本发明提供了可用作抗微生物剂的取代的恶唑烷酮衍生物。所公开的化合物可用于治疗或预防由细菌引起的或由细菌引起的病症，例如多重耐药葡萄球菌，链球菌，肠球菌，细菌属，梭菌属，分枝杆菌属。芽孢杆菌属，棒状杆菌属肝细胞线粒体利斯特氏菌属（Listeria spp。），军团菌属（Legionella spp。），嗜血杆菌流感，流感嗜血杆菌，大肠埃希氏菌和大肠埃希氏菌。提供了制备所公开化合物的方法，其药物组合物，以及治疗微生物感染的方法。

22. 发明申请

US20090176856A1 MUSCARINIC RECEPTOR ANTAGONISTS 审中-公开
标题翻译：肌肉受体拮抗剂
公开(公告)号：US20090176856A1
公开(公告)日：2009-07-09
申请号：US11576066
申请日：2005-09-26
申请人： Anita Mehta , Mohammad Salman , Pakala Kumara Savithru Sarma , Shelly Aeron , Anita Chugh , Suman Gupta
发明人： Anita Mehta , Mohammad Salman , Pakala Kumara Savithru Sarma , Shelly Aeron , Anita Chugh , Suman Gupta
IPC分类号： A61K31/403 , C07D209/52 , A61P13/00 , A61P11/00 , A61P11/06 , A61P3/04 , A61P3/10 , C07D405/08
CPC分类号： C07D471/08
摘要： This present invention generally relates to muscarinic receptor antagonists, which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to the process for the preparation of disclosed compounds, pharmaceutical compositions containing the disclosed compounds, and the methods for treating diseases mediated through muscarinic receptors.
摘要翻译：本发明一般涉及毒蕈碱受体拮抗剂，其可用于治疗通过毒蕈碱受体介导的呼吸，泌尿和胃肠系统的各种疾病，以及其它用途。本发明还涉及制备所公开的化合物的方法，含有所公开的化合物的药物组合物，以及用于治疗通过毒蕈碱受体介导的疾病的方法。

23. 发明授权

US07736237B2 Electromuscular incapacitation device and methods 有权
标题翻译：肌电无力的装置及方法
公开(公告)号：US07736237B2
公开(公告)日：2010-06-15
申请号：US11509086
申请日：2006-08-23
申请人： Kenneth J. Stethem , Casey Hathcock , Bruno D. V. Marino , Anita Mehta , Robert Randolph Bernard , James Lee , Viet Thinh Pho
发明人： Kenneth J. Stethem , Casey Hathcock , Bruno D. V. Marino , Anita Mehta , Robert Randolph Bernard , James Lee , Viet Thinh Pho
IPC分类号： F41B15/04
CPC分类号： A01K15/02 , A22B3/06 , F41B15/04 , F41H9/10 , F41H13/0018 , F41H13/0025 , F41H13/0087
摘要： Incapacitation of a mammalian subject results from the application of a pulsed, low-power electric waveform. The waveform is applied to the subject at a frequency and over a time period sufficient to induce involuntary muscular contraction. Additionally, the contraction causes limited lactic acid production and is non- or minimally-injurious to the subject's tissues. A device utilizing such a waveform is designed to control or otherwise subdue an individual.
摘要翻译：哺乳动物受试者的失能是由应用脉冲，低功率电波形引起的。该波形以足以引起不自主肌肉收缩的频率和时间周期施加于受试者。此外，收缩导致有限的乳酸产生并且对受试者的组织是非或最小的损伤。使用这种波形的装置被设计成控制或以其他方式使个人屈服。

24. 发明申请

US20080319002A1 Xanthine Derivatives a Useful as Muscarinic Receptor Antagonists 审中-公开
标题翻译：黄嘌呤衍生物有用作毒蕈碱受体拮抗剂
公开(公告)号：US20080319002A1
公开(公告)日：2008-12-25
申请号：US11570749
申请日：2004-06-16
申请人： Anita Mehta , Mohammad Salman , Pakala Kumara Savithru Sarma , Anita Chugh , Suman Gupta
发明人： Anita Mehta , Mohammad Salman , Pakala Kumara Savithru Sarma , Anita Chugh , Suman Gupta
IPC分类号： A61K31/4353 , C07D221/04 , A61P1/00 , A61P13/02 , A61P3/04 , A61P3/10 , A61P9/00
CPC分类号： C07D405/12 , C07D405/14
摘要： This present invention generally relates to xanthine derivatives as muscarinic receptor antagonists which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to the process for the preparation of disclosed compounds, pharmaceutical compositions containing the disclosed compounds, and the methods for treating diseases mediated through muscarinic receptors.
摘要翻译：本发明一般涉及作为毒蕈碱受体拮抗剂的黄嘌呤衍生物，其可用于治疗通过毒蕈碱受体介导的呼吸，泌尿和胃肠系统的各种疾病。本发明还涉及制备所公开的化合物的方法，含有所公开的化合物的药物组合物，以及用于治疗通过毒蕈碱受体介导的疾病的方法。

25. 发明授权

US06956040B2 Oxazolidinone piperazinyl derivatives as potential antimicrobials 失效
标题翻译：恶唑烷酮哌嗪衍生物作为潜在的抗菌药物
公开(公告)号：US06956040B2
公开(公告)日：2005-10-18
申请号：US10051784
申请日：2002-01-17
申请人： Anita Mehta , Sudershan K. Arora , Bis{umlaut over (w)}ajit Das , Abhijit Ray , Sonali Rudra , Ashok Rattan
发明人： Anita Mehta , Sudershan K. Arora , Bis{umlaut over (w)}ajit Das , Abhijit Ray , Sonali Rudra , Ashok Rattan
IPC分类号： C07D413/12 , C07D413/14 , A61K31/496 , A61P31/04
CPC分类号： C07D413/12
摘要： The present invention relates to certain substituted phenyl piperazinyl oxazolidinones, for example, to those having the structure of Formula I with the variables as defined within, and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
摘要翻译：本发明涉及某些取代的苯基哌嗪基恶唑烷酮，例如具有式I结构的具有变量的定义的那些，以及其合成方法。本发明还涉及含有作为抗微生物剂的本发明化合物的药物组合物。这些化合物是有用的抗微生物剂，对许多人类和兽医病原体有效，包括革兰氏阳性好氧细菌如多重耐药性葡萄球菌，链球菌和肠球菌以及厌氧生物如细菌属。和梭菌属（Clostridia spp。）物种和酸性快速生物如结核分枝杆菌，鸟分枝杆菌和分枝杆菌属。

26. 发明授权

US07560479B2 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists 失效
标题翻译： 3,6-二取代的氮杂双环己烷衍生物作为毒蕈碱受体拮抗剂
公开(公告)号：US07560479B2
公开(公告)日：2009-07-14
申请号：US10552502
申请日：2003-04-10
申请人： Anita Mehta , Bruhaspathy Miriyala , Arundutt Viswanatham Silamkoti , Jang Bahadar Gupta
发明人： Anita Mehta , Bruhaspathy Miriyala , Arundutt Viswanatham Silamkoti , Jang Bahadar Gupta
IPC分类号： A61K31/403 , C07D209/52
CPC分类号： C07D209/52
摘要： This invention relates to derivatives of 3,6-disubstituted azabicyclo hexanes. The compounds of this invention can function as muscarinic receptor antagonists and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors.
摘要翻译：本发明涉及3,6-二取代的氮杂双环己烷的衍生物。本发明的化合物可用作毒蕈碱受体拮抗剂，可用于治疗通过毒蕈碱受体介导的呼吸，泌尿和胃肠系统的各种疾病。

27. 发明申请

US20080214565A1 Oxazolidinone Derivatives as Antimicrobials 审中-公开
标题翻译：恶唑烷酮衍生物作为抗菌剂
公开(公告)号：US20080214565A1
公开(公告)日：2008-09-04
申请号：US10552322
申请日：2003-04-07
申请人： Anita Mehta , Sonali Rudra , Ajjarapu Venkata Subrahmanya Rajo Rao , Ajay Singh Yadav , Ashok Rattan
发明人： Anita Mehta , Sonali Rudra , Ajjarapu Venkata Subrahmanya Rajo Rao , Ajay Singh Yadav , Ashok Rattan
IPC分类号： A61K31/496 , C07D413/10 , A61P31/04
CPC分类号： C07D413/12 , C07D413/14
摘要： The present invention relates to certain substituted phenyl oxazolidinones of formula I and H and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms as Bacterioides spp. and Clostridia spp. species, and acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
摘要翻译：本发明涉及式I和H的某些取代的苯基恶唑烷酮及其合成方法。本发明还涉及含有作为抗微生物剂的本发明化合物的药物组合物。这些化合物是有用的抗微生物剂，对许多人类和兽医病原体有效，包括革兰氏阳性好氧细菌如多重耐药性葡萄球菌，链球菌和肠球菌以及厌氧生物作为细菌属。和梭菌属（Clostridia spp。）物种和酸性快速生物如结核分枝杆菌，鸟分枝杆菌和分枝杆菌属。

28. 发明申请

US20070265346A1 Combination therapy for the treatment and improvement of scars 审中-公开
标题翻译：联合治疗治疗和改善疤痕
公开(公告)号：US20070265346A1
公开(公告)日：2007-11-15
申请号：US11786085
申请日：2007-04-10
申请人： Anita Mehta
发明人： Anita Mehta
IPC分类号： A61K8/28 , A61K8/27 , A61K31/22 , A61K31/137
CPC分类号： A61K9/0024 , A61K9/0014 , A61K31/277 , A61L15/44 , A61L2300/404 , A61L2300/412 , A61L2300/416 , A61L2300/426 , A61L2300/434 , A61L2300/45
摘要： The present invention is a composition, methods of using that composition and kits including that composition, useful for reducing the size and improving the appearance of a closed wound wherein the composition comprises a therapeutically effective amount of a hydrophilic or hydrophobic carrier (or a mixture thereof), at least one matrix metalloproteinase (MMP) modulator in combination with one or more of the following pharmaceutically active agents: (a) cell cycle modulators; (b) inflammatory event modulators; (c) angiogenesis event modulators; (d) fibroblast migration agents; (e) fibroblast proliferation agents; (f) tissue remodeling correcting agents; (g) antimicrobial agents; (h)modulators of deposition of extra cellular matrix; (i) penetration enhancers; (j) antioxidants; (k) antipuritic agents; (l) fibrinolytic agents; (j) immunomodulators; (m) transcription modulating agents; (n) surface modulating agents; (o) growth factor inhibitors; and (p) anti-proliferative agents.
摘要翻译：本发明是组合物，使用该组合物和试剂盒的方法，所述组合物和试剂盒包括该组合物，其可用于减小封闭伤口的尺寸和改善外观，其中所述组合物包含治疗有效量的亲水或疏水载体（或其混合物），至少一种基质金属蛋白酶（MMP）调节剂与一种或多种以下药物活性剂的组合：（a）细胞周期调节剂; （b）炎性事件调节剂; （c）血管发生事件调节剂; （d）成纤维细胞迁移剂; （e）成纤维细胞增殖剂; （f）组织重塑修正剂; （g）抗微生物剂; （h）细胞外基质的沉积调节剂; （i）渗透增强剂; （j）抗氧化剂; （k）防腐剂; （l）纤维蛋白溶解剂; （j）免疫调节剂; （m）转录调节剂; （n）表面调节剂; （o）生长因子抑制剂; 和（p）抗增殖剂。

29. 发明申请

US20060122253A1 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists 失效
标题翻译：用作毒蕈碱受体拮抗剂的3,6-二取代的氮杂双环[3.1.0]己烷衍生物
公开(公告)号：US20060122253A1
公开(公告)日：2006-06-08
申请号：US10523208
申请日：2002-07-31
申请人： Anita Mehta , Arundutt Silamkoti , Kirandeep Kaur , Jang Gupta
发明人： Anita Mehta , Arundutt Silamkoti , Kirandeep Kaur , Jang Gupta
IPC分类号： A61K31/403 , C07D209/52
CPC分类号： C07D209/52
摘要： This invention generally relates to the derivatives of 3,6 disubstituted azabicyclo[3.1.0]hexanes. The compounds of this invention are muscarinic receptor antagonists which are useful, inter-alia, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods for treating the diseases mediated through muscarinic receptors.
摘要翻译：本发明一般涉及3,6-二取代的氮杂双环[3.1.0]己烷的衍生物。本发明的化合物是毒蕈碱受体拮抗剂，其特别用于治疗通过毒蕈碱受体介导的呼吸，尿和胃肠道系统的各种疾病。本发明还涉及制备本发明化合物的方法，含有本发明化合物的药物组合物和通过毒蕈碱受体介导的疾病的治疗方法。

30. 发明申请

US20060004083A1 Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists 失效
标题翻译：含有3,6-二取代的氮杂二环（3.1.0）己烷衍生物的氟磺酰氨基作为毒蕈碱受体拮抗剂
公开(公告)号：US20060004083A1
公开(公告)日：2006-01-05
申请号：US10525439
申请日：2002-08-23
申请人： Anita Mehta , Jang Gupta
发明人： Anita Mehta , Jang Gupta
IPC分类号： A61K31/403 , C07D209/02
CPC分类号： C07D209/94 , C07D209/52
摘要： This invention generally relates to the derivatives of novel 3,6 disubstituted azabicyclo[3.1.0] hexane's. The compounds of this invention are MUSCARINIC receptor antagonists which are useful, inter-ail for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through MUSCARINIC receptors. The invention also relates to processes for the preparation of the compounds of the invention, pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through MUSCARINIC receptors.
摘要翻译：本发明一般涉及新的3,6-二取代的氮杂双环[3.1.0]己烷的衍生物。本发明的化合物是MUSCARINIC受体拮抗剂，其可用于治疗通过MUSCARINIC受体介导的呼吸，尿和胃肠道系统的各种疾病。本发明还涉及制备本发明化合物的方法，含有本发明化合物的药物组合物和通过MUSCARINIC受体介导的疾病的治疗方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式