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21. 发明申请

WO2007061843A8 REMOTELY RF POWERED COMFORMABLE THERMAL APPLICATORS 审中-公开
公开(公告)号：WO2007061843A8
公开(公告)日：2007-08-16
申请号：PCT/US2006044672
申请日：2006-11-17
申请人： INTEMATIX CORP , XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
发明人： XIANG XIAO-DONG , WANG GANG , YANG HAITAO , MELMAN JONATHAN , DIONNE GERALD FRANCIS
IPC分类号： A61F2/00
CPC分类号： A61N1/406 , A61K41/0052 , A61K49/1818
摘要： The present embodiments are directed to cancer therapy; specifically a technique called "nanoparticle ferromagnetic resonance heating," where ferromagnetic resonance heating in addition to an RF hyperthermia treatment is used to cause cancer cell apoptosis and necrosis. An apparatus for carrying out a ferromagnetic resonance heating treatment of a tumor, comprises a volume concentration of super paramagnetic particles contained within the interior of the tumor, the concentration ranging from about 0.1 to about 1 percent; a magnetic field source configured to deliver a gradient DC magnetic field to the region of the tumor; and an energy source configured to deliver to the tumor an RF field at a frequency ranging from about 100 to 200 MHz. The apparatus of claim 1, wherein the super paramagnetic particles are selected from the group consisting of maghemite (?-Fe 2 O 3 ) based compounds, and yttrium iron garnet (Y 3 Fe 5 O 12 ) based compounds.

22. 发明申请

WO2006026770A3 INTEGRATED EWP-STM SPIN RESONANCE MICROSCOPE 审中-公开
标题翻译：集成EWP-STM自旋共振微阵列
公开(公告)号：WO2006026770A3
公开(公告)日：2007-04-12
申请号：PCT/US2005031514
申请日：2005-08-31
申请人： INTEMATIX CORP , XIANG XIAO-DONG , YANG HAITAO
发明人： XIANG XIAO-DONG , YANG HAITAO
IPC分类号： G01V3/00 , H01J3/14
CPC分类号： G01R33/60 , B82Y35/00 , G01N24/10 , G01Q30/02 , G01Q60/12 , G01R33/26 , G01R33/323 , G01R33/4808
摘要： A spin resonance microscope is disclosed, the microscope design comprising an integrated evanescent wave probe (11) and scanning tunneling microscope tip (17). The probe and tip may be either the same structure, or they may be separate structures. The integrated design allows for coherent excitation of precessing electron spin states in the sample (18) such that spin resonance may be detected because the tunneling current is modulated by the spin resonance. Spin resonance may be affected by either adjacent nuclei, or by adjacent electrons. The present apparatus (10) requires significantly reduced power inputs, such that the dead time of the system is short, and relaxation phenomena may be evaluated without swamping the instrument's electronics.
摘要翻译：公开了一种旋转共振显微镜，显微镜设计包括集成的ev逝波探测器（11）和扫描隧道显微镜尖端（17）。探针和尖端可以是相同的结构，或者它们可以是分离的结构。该集成设计允许在样品（18）中进行的电子自旋状态的相干激发，使得可以检测自旋共振，因为隧道电流由自旋共振调制。旋转共振可能受相邻核或相邻电子的影响。本装置（10）需要显着降低的功率输入，使得系统的死区时间短，并且可以评估松弛现象而不会使仪器的电子元件变形。

23. 发明申请

WO2006086677A2 ENDOHEDRAL FULLERENES AS SPIN LABELS AND MRI CONTRAST AGENTS 审中-公开
标题翻译： ENDHEDRAL FULLERENES作为旋转标签和MRI对比剂
公开(公告)号：WO2006086677A2
公开(公告)日：2006-08-17
申请号：PCT/US2006/004815
申请日：2006-02-08
申请人： INTEMATIX CORPORATION , XIANG, Xiao, Dong , YANG, Haitao , DIONNE, Gerald, F.
发明人： XIANG, Xiao, Dong , YANG, Haitao , DIONNE, Gerald, F.
IPC分类号： A61K49/08
CPC分类号： B82Y5/00 , A61K49/189 , Y10T436/13
摘要： This invention pertains to the discovery that certain endohedral fullerenes are functional paramagnetic materials exhibiting increased relaxation times. These endohedral fullerenes provide improved labels for use in electron spin resonance (ESR) detection systems.
摘要翻译：本发明涉及某些内含面富勒烯是表现出增加的松弛时间的功能顺磁材料的发现。这些内嵌的富勒烯提供了用于电子自旋共振（ESR）检测系统的改进的标记。

24. 发明申请

WO2006017249A3 EVANESCENT MICROWAVE PROBE WITH ENHANCED RESOLUTION AND SENSITIVITY 审中-公开
公开(公告)号：WO2006017249A3
公开(公告)日：2006-02-16
申请号：PCT/US2005/024597
申请日：2005-07-12
申请人： INTEMATIX CORPORATION , XIANG, Xiao-Dong , YANG, Haitao , WANG, Gang
发明人： XIANG, Xiao-Dong , YANG, Haitao , WANG, Gang
IPC分类号： G01R31/02
摘要： Novel systems of an evanescent microwave probe (EWP) are disclosed, which enable measurements of physical properties of a sample with enhanced sensitivity and resolution, simultaneously. In one embodiment, new shielding features are added to the probe (which may be of either a sharpened tip or loop configuration) to reduce the effects of residual far field radiation, while maintaining the probe section that extends beyond the shielding aperture of the resonator. To further increase the sensitivity of the instrument, an automatic gain-controlled active feedback loop system may be added to the probe resonator to form a self-oscillator. This new active circuit feature significantly increases the effective Q of the resonator probe, enhancing the sensitivity of both the frequency and Q measurement.

25. 发明申请

WO2011044274A9 SOLID-STATE LAMPS WITH PASSIVE COOLING 审中-公开
标题翻译：具有无源冷却功能的固态灯
公开(公告)号：WO2011044274A9
公开(公告)日：2012-05-24
申请号：PCT/US2010051680
申请日：2010-10-06
申请人： INTEMATIX CORP , LI YI-QUN , YANG HAITAO
发明人： LI YI-QUN , YANG HAITAO
IPC分类号： F21V29/02
CPC分类号： F21V29/004 , F21K9/233 , F21K9/64 , F21S8/026 , F21S8/033 , F21V29/503 , F21V29/505 , F21V29/507 , F21V29/74 , F21V29/83 , F21V29/89 , F21Y2115/10
摘要： A solid-state lamp comprises a body having a first chamber with inlet apertures and a second chamber with outlet apertures. The chambers are interconnected in fluid communication by one or more passages. The lamp further comprises a thermally conductive substrate having a heat radiating surface located within at least one chamber and one or more solid-state light emitters, typically LEDs, mounted in thermal communication with the thermally conductive substrate. The lamp is configured such that in operation heat generated by the LEDs is radiated by the substrate into one or both chambers causing a difference in air pressure between the chambers that results in surrounding air being drawn into the inlet apertures, flowing through the chambers via the interconnecting passages in the substrate and exiting through the outlet apertures thereby cooling the substrate and LEDs.
摘要翻译：固态灯包括具有带有入口孔的第一室的主体和具有出口孔的第二室。腔室通过一个或多个通道流体连通地相互连接。该灯还包括导热基底，其具有位于至少一个腔室内的散热表面和一个或多个固体发光体，通常为LED，其安装成与导热基底热连通。灯被配置为使得在操作中，由LED产生的热量被衬底辐射到一个或两个室中，导致室之间的空气压力差，导致周围的空气被吸入到入口孔中，经由腔在衬底中连接通道并通过出口孔离开，从而冷却衬底和LED。

26. 发明申请

WO2011019753A1 LED-BASED LAMPS 审中-公开
标题翻译：基于LED的LAMPS
公开(公告)号：WO2011019753A1
公开(公告)日：2011-02-17
申请号：PCT/US2010/045074
申请日：2010-08-10
申请人： INTEMATIX CORPORATION , YANG, Haitao
发明人： YANG, Haitao
IPC分类号： F21S8/00
CPC分类号： F21V7/0025 , A47F3/001 , A47F11/10 , F21S4/28 , F21S8/02 , F21S8/033 , F21V7/0008 , F21V7/0016 , F21V7/0033 , F21V7/005 , F21V7/09 , F21V9/30 , F21V9/40 , F21W2131/305 , F21W2131/405 , F21Y2103/10 , F21Y2115/10
摘要： A LED-lamp (lighting bar) comprises a plurality of solid state light emitters (LEDs) configured as an elongate (linear) array and a generally concave cylindrical light reflective surface disposed along the length of the array of LEDs. The concave light reflective surface is configured to direct light over an illumination plane located to a side of the lamp. The LEDs can be configured such that their emission axes are oriented to the illumination plane at an angle of between 0° and 90. The lamp can further comprise a second generally concave cylindrical light reflective surface in which the concave light reflective surfaces are configured to direct light over illumination planes located on respective sides of the lamp. There is also disclosed a panel lamp and sign incorporating the lamp(s) of the invention.
摘要翻译： LED灯（照明条）包括被配置为细长（线性）阵列的多个固态发光体（LED）和沿LED阵列的长度设置的大致凹入的圆柱形光反射表面。凹面光反射表面被配置为将光引导到位于灯的一侧的照明平面上。 LED可以被配置为使得它们的发射轴以0°和90°之间的角度定向到照明平面。灯还可以包括第二大体上凹入的圆柱形光反射表面，其中凹光反射表面被配置成直接照亮位于灯的相应侧面的照明平面。还公开了一种装有本发明的灯的面板灯和符号。

27. 发明申请

WO2006116403A3 INTRACELLULAR THERMAL ABLATION USING NANO-PARTICLE ELECTRON SPIN RESONANCE HEATING 审中-公开
标题翻译：使用纳米颗粒电子旋转谐振加热的细胞内热吸收
公开(公告)号：WO2006116403A3
公开(公告)日：2007-11-29
申请号：PCT/US2006015632
申请日：2006-04-24
申请人： INTEMATIX CORP , XIANG XIAO DONG , YANG HAITAO
发明人： XIANG XIAO DONG , YANG HAITAO
IPC分类号： A61B5/055 , A61K49/00
CPC分类号： A61K41/0052 , B82Y5/00
摘要： This invention pertains to the use of spin resonance absorption heating as a therapeutic treatment method wherein electron spin resonance absorption of superparamagnetic (SPM) nanoparticles can be used as an intracellular heating method, more preferably as an in vivo heating method that can be utilized in a variety of therapeutic contexts and can further allow for resonance imaging and internal thermometry.
摘要翻译：本发明涉及使用自旋共振吸收加热作为治疗处理方法，其中超顺磁（SPM）纳米颗粒的电子自旋共振吸收可以用作细胞内加热方法，更优选作为体内加热方法，可用于各种治疗情境，并可进一步允许共振成像和内部测温。

28. 发明申请

WO2006116021A2 MRI TECHNIQUE BASED ON ELECTRON SPIN RESONANCE AND ENDOHEDRAL CONTRAST AGENT 审中-公开
标题翻译：基于电子螺旋共振和内相对比剂的MRI技术
公开(公告)号：WO2006116021A2
公开(公告)日：2006-11-02
申请号：PCT/US2006014987
申请日：2006-04-21
申请人： INTEMATIX CORP , XIANG XIAO DONG , YANG HAITAO
发明人： XIANG XIAO DONG , YANG HAITAO
IPC分类号： A61K49/00
CPC分类号： A61K49/12 , A61K41/0052
摘要： Methods and systems for electron spin MRI (eMRI) and novel methods for fabricating N@C 60 fullerenes using the discovery that certain endohedral fullerenes can be used as functional paramagnetic materials exhibiting increased relaxation times. These endohedral fullerenes provide improved labels for use in electron spin resonance (ESR) detection systems.
摘要翻译：使用电子自旋MRI（eMRI）的方法和系统以及用于制造N C 60 F富勒烯的新方法，其发现某些内含面富勒烯可用作表现出增加的弛豫时间的功能顺磁材料。这些内嵌的富勒烯提供了用于电子自旋共振（ESR）检测系统的改进的标记。

29. 发明申请

WO2006026770A2 INTEGRATED EWP-STM SPIN RESONANCE MICROSCOPE 审中-公开
标题翻译：集成EWP-STM自旋共振微阵列
公开(公告)号：WO2006026770A2
公开(公告)日：2006-03-09
申请号：PCT/US2005/031514
申请日：2005-08-31
申请人： INTEMATIX CORPORATION , XIANG, Xiao-Dong , YANG, Haitao
发明人： XIANG, Xiao-Dong , YANG, Haitao
IPC分类号： G01V3/00
CPC分类号： G01R33/60 , G01N24/10 , G01Q30/02 , G01Q60/12 , G01R33/26 , G01R33/323 , G01R33/4808
摘要： A novel spin resonance microscope is disclosed, the microscope design comprising an integrated evanescent wave probe and scanning tunneling microscope tip. The probe and tip may be either the same structure, or they may be separate structures. The integrated design allows for coherent excitation of precessing electron spin states in the sample such that spin resonance may be detected because the tunneling current is modulated by the spin resonance. Spin resonance may be affected by either adjacent nuclei, or by adjacent electrons. The present apparatus requires significantly reduced power inputs, such that the dead time of the system is short, and relaxation phenomena may be evaluated without swamping the instrument's electronics.
摘要翻译：公开了一种新型的自旋共振显微镜，显微镜设计包括集成的ev逝波探针和扫描隧道显微镜尖端。探针和尖端可以是相同的结构，或者它们可以是分离的结构。该集成设计允许在样品中进行电子自旋状态的相干激发，使得可以检测自旋共振，因为隧道电流被自旋共振调制。旋转共振可能受相邻核或相邻电子的影响。本装置需要显着降低的功率输入，使得系统的死区时间短，并且可以评估松弛现象而不会使仪器的电子元件变形。

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