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    • 22. 发明申请
    • PATIENT CONTROLLED DRUG DELIVERY DEVICE
    • 患者控制药物递送装置
    • WO1996040332A1
    • 1996-12-19
    • PCT/AU1996000345
    • 1996-06-07
    • O'NEIL, ChristineO'NEIL, Alexander, George, Brian
    • O'NEIL, Christine
    • A61M11/06
    • B05B11/3001A61M11/002A61M15/0065A61M15/0081A61M15/0083A61M2005/1405A61M2202/04B05B11/0056
    • A delivery device for patient-controlled infusion of a medicament (6), the delivery device comprising a reservoir (2) for the medicament (6) and a pump (4) having a predetermined delivery dose which is capable of displacing the medicament from the reservoir (2) and delivering it to a patient, wherein the pump (4) comprises a pumping means (14), a first conduit (10), capable of restricting flow rate, chosen in conjunction with the delivery dose of the pumping means (14) to define a predetermined maximum dosage rate, said conduit (10) connecting the reservoir (2) to a pumping means (14), a one-way valve (18) in fluid communication with the first conduit (10) and the pumping means (14) which permits medicament flow into the pumping means (14) but prevents reverse flow, a controlling means (32), and a second conduit (28) extending from the pumping means and having a distal end (30) through which the medicament may be released, wherein the controlling means (32), (a) is in fluid communication with the pumping means (12) and the second conduit (28); (b) opens when pressure within the dose chamber (12) exceeds a predetermined minimum opening pressure for the controlling means (32); and, (c) is adapted to prevent the reverse flow of medicament and air into the pumping means.
    • 一种用于患者控制地输注药物(6)的递送装置,所述递送装置包括用于药物(6)的储存器(2)和具有预定递送剂量的泵(4),所述泵(4)能够将药物从 储存器(2)并将其输送到患者,其中所述泵(4)包括泵送装置(14),能够限制流量的第一管道(10),所述第一管道(10)结合所述泵送装置的输送剂量 14)以限定预定的最大剂量率,所述导管(10)将储存器(2)连接到泵送装置(14),与第一导管(10)流体连通的单向阀(18) 允许药物流入泵送装置(14)但防止反向流动的装置(14),控制装置(32)和从泵送装置延伸并具有远端(30)的第二导管(28),通过该远端 药物可以被释放,其中控制装置(32)(a)是流体连通的 在泵送装置(12)和第二导管(28)上; (b)当所述剂量室(12)内的压力超过所述控制装置(32)的预定最小开启压力时打开; 和(c)适于防止药物和空气逆向流入泵送装置。
    • 28. 发明申请
    • PATIENT CONTROLLABLE DRUG DELIVERY SYSTEM FLOW REGULATING MEANS
    • 患者可控制药物输送系统流量调节手段
    • WO1997033637A1
    • 1997-09-18
    • PCT/AU1997000167
    • 1997-03-14
    • O'NEIL, ChristineO'NEIL, Alexander, George, Brian
    • O'NEIL, Christine
    • A61M05/142
    • A61M5/1424A61M2005/1405
    • A patient controllable drug delivery system including a metering device (30) having an intermittent dose reservoir (34) and a plunger, a main reservoir (26), a fill line (32) connecting the main reservoir (26) and the intermittent reservoir (34) via a metering device fill point (26) and a flow regulating means (10) between the metering device (30) and the patient line (36), the flow regulating means (10) comprising a means for receiving and dispensing a dose of drug (12) and a pressure set one way valve (16), the intermittent dose reservoir (34) and the patient line (36) being in restricted fluid communication, dispensation of the drug being effected by pressure applied by the receiving and dispensing means (12). Systems for the supply of a continuous dose in addition to the patient controllable delivered dose, and a secondary delivery system are also disclosed.
    • 一种患者可控药物递送系统,包括具有间歇剂量储存器(34)和柱塞的计量装置(30),主储存器(26),连接主储存器(26)和间歇储存器(26)的填充管线(32) 34)通过计量装置填充点(26)和在计量装置(30)和患者管线(36)之间的流量调节装置(10),流量调节装置(10)包括用于接收和分配剂量 的药物(12)和压力单向阀(16),间歇剂量储存器(34)和患者管线(36)处于受限制的流体连通中,药物的分配由通过接收和分配施加的压力 手段(12)。 还公开了除患者可控递送剂量之外还提供连续剂量的系统,以及二次递送系统。
    • 30. 发明申请
    • FLUID COUPLINGS
    • 流体联轴器
    • WO1991010861A1
    • 1991-07-25
    • PCT/GB1990002012
    • 1990-12-21
    • PATTULLO, NormanO'NEIL, Alexander, George, Brian
    • PATTULLO, Norman
    • F16L39/02
    • F16L39/02A61M39/10A61M2039/1033Y10S604/905
    • A fluid coupling for connecting a plurality of fluid sources to a single-bore outlet member, said coupling comprising a plurality of tubes (44, 46, 48) mutually conjoined within a connector (42) for attachment of said outlet member, each said tube extending through said connector to terminate at a point (43) which is substantially contiguous with said outlet member when attached to said connector, the lumens of each said tube being mutually isolated by the tube walls until the termination of the tubes at said point, whereby in use of said fluid coupling with said single-bore outlet member connected thereto, fluid passing down any of said tubes discharges from the end of the respective tube substantially directly into the bore of said outlet member.
    • 用于将多个流体源连接到单孔出口构件的流体联接器,所述联接器包括在连接器(42)内相互连接的多个管(44,46,48),用于附接所述出口构件,每个所述管 延伸穿过所述连接器以在连接到所述连接器时终止于与所述出口构件基本邻接的点(43),每个所述管的管腔由管壁相互隔离,直到在所述点处终止管,由此 在使用与连接到其上的所述单孔出口构件的所述流体联接器的情况下,流过任何所述管的流体基本上直接从相应管的端部排出到所述出口构件的孔中。