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21. 发明申请

WO2005016119A2 RADIO-FREQUENCY BASED CATHETER SYSTEM AND METHOD FOR ABLATING BIOLOGICAL TISSUES 审中-公开
标题翻译：基于无线电频率的导管系统及其生物组织研究方法
公开(公告)号：WO2005016119A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/024696
申请日：2004-07-30
申请人： MEDWAVES, INC. , ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
发明人： ORMSBY, Theodore, C. , LAW, Ming-Fan , LEUNG, George, L.
IPC分类号： A61B
CPC分类号： A61B18/1492 , A61B18/18 , A61B90/39 , A61B2017/003 , A61B2018/00214 , A61B2018/00839 , A61B2018/00875 , A61B2018/1407 , A61B2018/1437
摘要： An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency ("RF") generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements. The RF antenna is steered by the steering control lines to establish its body vessel conformation. The catheter system is energized and system senses the reflected RF power relative to its output power and adjusts the frequency of the power output to effect impedance match between the transmission line of the system and the tissue ablation load.
摘要翻译：改进的基于射频的导管系统和用于消除患者体内血液中生物组织的方法包括：射频（“RF”）发生器，用于在具有RF同轴传输线的可展开导管中选择性地产生高频能量具有中空管腔，安装在导管的远端部分上的RF天线以及用于转向导管的传输线的内腔中的转向控制线，同时插入到身体容器中并用于偏转RF天线以适应需要组织消融的身体血管。具有可变输出频率的RF发生器适于产生RF通信并将RF能量传送到RF天线，其使得天线 - 组织界面的反射能量最小化。在应用中，RF天线与体内血管建立接触线，以符合其内部轮廓，以规定精确的组织消融路径，尽管身体血管运动。 RF天线由转向控制线转向以建立其身体血管构象。导管系统被通电，系统相对于其输出功率感测反射的RF功率，并且调节功率输出的频率以实现系统的传输线与组织消融负载之间的阻抗匹配。

22. 发明专利

ES2497567T3 Sistema de ablación basado en radiofrecuencia que comprende un transformador dieléctrico 未知
公开(公告)号：ES2497567T3
公开(公告)日：2014-09-23
申请号：ES10765195
申请日：2010-04-15
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE , CHUNG RUSSELL , LEUNG GEORGE , SHEN GWO JENN
IPC分类号： A61B18/18 , A61B17/3205
摘要： Un dispositivo para transmitir energía de radiofrecuencia para la ablación de tejido biológico, que comprende: un elemento (44) exterior tubular alargado, conductor de la electricidad, que tiene una luz axial; un elemento (42) interior alargado, conductor de la electricidad, situado en una relación espaciada con respecto al elemento (44) exterior dentro de la luz del citado elemento (44) exterior para definir una guía de ondas (42, 44) para transmisión de energía RF en el rango de frecuencias de las microondas y mayores; una antena (35) situada en el extremo distal del dispositivo acoplada eléctricamente a al menos el elemento (42) interior y adaptada para recibir y radiar la energía RF para la ablación de tejidos biológicos, teniendo la antena (35) una superficie exterior; y al menos una primera capa (74) exterior y una segunda capa (75) exterior de medios dieléctricos diferentes situadas alrededor del elemento (44) exterior y que se extienden a lo largo de al menos una parte de la longitud del citado elemento (44) exterior, donde la primera capa (74) exterior tiene una porción final distal que se proyecta más allá de un extremo distal de la segunda capa (75) exterior, donde la segunda capa (75) exterior está situada alrededor de la primera capa (74) exterior, y donde el extremo distal del elemento (44) exterior está escalonado desde los extremos distales de ambas capas (74, 75) exteriores, para formar un transformador dieléctrico longitudinal con capas dieléctricas longitudinalmente escalonadas, con el fin de proporcionar transición gradual desde la citada guía de ondas (42, 44) hasta la citada antena (35) para reducir la reflexión RF en el punto de ablación del dispositivo.

23. 发明专利

DE112010004615T5 RADIO FREQUENZ ABLATION SYSTEM MIT TRACKING SENSOR 未知
公开(公告)号：DE112010004615T5
公开(公告)日：2013-01-24
申请号：DE112010004615
申请日：2010-11-24
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE C , SHEN GWO JENN , LEUNG GEORGE L
IPC分类号： A61B18/18 , A61B18/12 , A61B18/14
摘要： Ein RF Ablationssystem hat einen hohlen leitenden Koaxialkabel mit inneren und äußeren koaxialen rohrförmigen Leitungen, und ein Ablations-Element am distalen Ende des Kabels zur Abgabe von Radiofrequenzenergie einschließlich von Mikrowellen in die Ziel-Körpergewebe angebracht. Die Innenleitung hat ein zentrales Lumen der sich zumindest bis zum Ablations-Element erstreckt. Mindestens eine elektromagnetische Spule mit einem magnetischen Kern befinded sich im mittleren Itlmen am distalen Ende des Kabels an der distalen Spitze des Kabels und mit einer Signalverarbeitungseinheit. Ein elektromagnetisches Feld Generator ist in der Nähe eines zu behandelnden Patienten positioniert und erzeugt ein elektromagnetisches Feld, das eine Spannung in der Sensorspule induziert. Die Signalverarbeitungseinheit verwendet die induzierte Spannung, um die Position und Orientierung des distalen End-Abschnitt oder der Spitze des Katheters in den Körper eines Patienten zu berechnen.

24. 发明专利

AT493087T 未知
公开(公告)号：AT493087T
公开(公告)日：2011-01-15
申请号：AT04779679
申请日：2004-07-30
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE , LAW MING-FAN , LEUNG GEORGE
IPC分类号： A61B18/04 , A61B20060101 , A61B18/12 , A61B18/14
摘要： A method for biological tissue ablation includes shaping a shapeable RF antenna to accommodate the contour of a body vessel adjacent a biological tissue load; generating a train of radio frequency (RF) energy pulses at an output frequency for transmission in a transmission line to the shapeable RF antenna adjacent the biological tissue load; sensing a reflected signal and a forward signal of the RF energy pulses; and adjusting output frequency of the RF energy pulses to effect a substantial match of transmission line impedance with shapeable RF antenna and biological tissue load impedance.

25. 发明专利

DE60222934D1 未知
公开(公告)号：DE60222934D1
公开(公告)日：2007-11-22
申请号：DE60222934
申请日：2002-11-27
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
IPC分类号： A61B18/12 , A61B18/18 , A61B5/04 , A61B18/14 , H01Q1/36 , H01Q1/42
摘要： A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.

26. 发明专利

DE69925715T2 未知
公开(公告)号：DE69925715T2
公开(公告)日：2006-03-23
申请号：DE69925715
申请日：1999-12-08
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE C , LEUNG GEORGE L , LAW MING-FAN
IPC分类号： A61B17/00 , A61B18/12 , A61B18/14 , A61B18/18 , H01B11/18
摘要： A method of ablating body tissue using a catheter which has an ablating element to deliver radio-frequency frequency energy to body tissue and an electrical hollow cable to conduct radio-frequency energy between a radio-frequency energy source and the ablating element. The electrical hollow cable used has first and second coaxial elongate electrically conductive tubular members coupled to the ablating element. A tubular dielectric member is disposed between the first and second tubular members without an air gap therebetween. There is an axial lumen through which the deployable guide is slidably received. In the method, the ablating member is deployed out of the catheter by eliding the electrical hollow cable over the deployable guide; and the body tissue is ablated with the ablating element.

27. 发明专利

HK1073239A1 RADIO-FREQUENCY-BASED CATHETER SYSTEM WITH IMPROVED DEFLECTION AND STEERING MECHANISMS 未知
公开(公告)号：HK1073239A1
公开(公告)日：2005-09-30
申请号：HK05106061
申请日：2005-07-18
申请人： MEDWAVES INC
发明人： ORMSBY THEODORE C , LAW MING-FAN , LEUNG GEORGE L
IPC分类号： A61B18/12 , A61B20100101 , A61B18/14 , A61B18/18 , H01Q20100101 , H01Q1/42
摘要： A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.

28. 发明申请

WO2010121040A3 ELECTRICALLY TUNABLE TISSUE ABLATION SYSTEM AND METHOD 审中-公开
标题翻译：电动可控组织吸收系统和方法
公开(公告)号：WO2010121040A3
公开(公告)日：2011-03-31
申请号：PCT/US2010031259
申请日：2010-04-15
申请人： MEDWAVES INC , ORMSBY THEODORE , CHUNG RUSSELL , LEUNG GEORGE , SHEN GWO JENN
发明人： ORMSBY THEODORE , CHUNG RUSSELL , LEUNG GEORGE , SHEN GWO JENN
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1869
摘要： An ablation system which transmits radio frequency (RF) energy for the ablation of biological tissues has a transmission line and an RF antenna disposed at the distal portion of the transmission line. An RF signal generator supplies RF energy to the proximal end of the cable for transmission to the antenna, and an electrically tunable transformer is connected between the signal generator and the antenna. The transformer is tuned based on detection of the reflected power level from the antenna so as to reduce or minimize reflected power, thereby increasing RF energy coupling between the antenna and tissue.
摘要翻译：传输用于生物组织消融的射频（RF）能量的消融系统具有设置在传输线的远端部分的传输线和RF天线。 RF信号发生器将RF能量提供给电缆的近端以传输到天线，并且电可变变压器连接在信号发生器和天线之间。基于从天线的反射功率电平的检测来调整变压器，以便减少或最小化反射功率，从而增加天线和组织之间的RF能量耦合。

29. 发明申请

WO2010121040A2 ELECTRICALLY TUNABLE TISSUE ABLATION SYSTEM AND METHOD 审中-公开
标题翻译：电动可控组织吸收系统和方法
公开(公告)号：WO2010121040A2
公开(公告)日：2010-10-21
申请号：PCT/US2010/031259
申请日：2010-04-15
申请人： MEDWAVES, INC. , ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
发明人： ORMSBY, Theodore , CHUNG, Russell , LEUNG, George , SHEN, Gwo Jenn
IPC分类号： A61B18/18 , A61B17/3205
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1869
摘要： An ablation system which transmits radio frequency (RF) energy for the ablation of biological tissues has a transmission line and an RF antenna disposed at the distal portion of the transmission line. An RF signal generator supplies RF energy to the proximal end of the cable for transmission to the antenna, and an electrically tunable transformer is connected between the signal generator and the antenna. The transformer is tuned based on detection of the reflected power level from the antenna so as to reduce or minimize reflected power, thereby increasing RF energy coupling between the antenna and tissue.
摘要翻译：传输用于生物组织消融的射频（RF）能量的消融系统具有设置在传输线的远端部分的传输线和RF天线。 RF信号发生器将RF能量提供给电缆的近端以传输到天线，并且电可变变压器连接在信号发生器和天线之间。基于从天线的反射功率电平的检测来调整变压器，以便减少或最小化反射功率，从而增加天线和组织之间的RF能量耦合。

30. 发明申请

WO2008051708A2 ABLATION CATHETER APPARATUS WITH ONE OR MORE ELECTRODES 审中-公开
标题翻译：具有一个或多个电极的消融导管设备
公开(公告)号：WO2008051708A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/080819
申请日：2007-10-09
申请人： MEDWAVES, INC. , ORMSBY, Theodore C. , LEUNG, George L. , SHEN, Gwo Jenn , CHU, Peter
发明人： ORMSBY, Theodore C. , LEUNG, George L. , SHEN, Gwo Jenn , CHU, Peter
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B2017/003 , A61B2018/00839 , A61B2018/00916 , A61B2018/00946 , A61B2018/183
摘要： A radio frequency (RF) ablation catheter has a flexible distal end portion so that it can be deflected to position an antenna disposed in the distal end portion adjacent a tissue site to be treated. At least one electrical conductor is coupled to the antenna and extends through the catheter to the proximal end of the catheter to a connector at the proximal end of the catheter for connection to a power supply for the RF antenna. At least one electrode is disposed at the distal end portion of the catheter and electrically coupled to the proximal end connector for connection to a monitor. The electrode is of a flexible, electrically conductive material such as conductive polymer material. The electrode may be an electrocardiogram (ECG) electrode.
摘要翻译：射频（RF）消融导管具有柔性远端部分，使得其可偏转以将设置在远端部分中的天线定位在待治疗的组织部位附近。至少一个电导体联接到天线并且穿过导管延伸到导管的近端到位于导管近端的连接器，用于连接到RF天线的电源。至少一个电极设置在导管的远端部分处并电耦合到近端连接器以连接到监视器。电极是柔性的导电材料，例如导电聚合物材料。电极可以是心电图（ECG）电极。

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