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    • 23. 发明专利
    • Novel dipeptide compound and medicinal use thereof
    • NZ514017A
    • 2003-10-31
    • NZ51401700
    • 2000-12-28
    • JAPAN ENERGY CORP
    • MIMOTO TSUTOMUTERASHIMA KEISUKETAKAKU HARUOMATSUMOTO SHINJISHINTANI MAKOTONOJIMA SHUN
    • A61P31/18C07D207/16C07D277/06C07K5/023A61K31/426C07D207/14C07D277/04
    • A dipeptide compound as shown by formula (I) wherein: R1, R2 and R3 independently represent a linear or branched, saturated or unsaturated lower alkyl group, alkoxyl group, alkyl amino group, or dialkyl amino group having 1-4 carbon atoms (with a carbon atom being either replaced by an oxygen atom or not), a halogeno group, or a hydrogen atom, provided that all of the R1, R2 and R3 are not a hydrogen atom at the same time, R2 and R3 may form a ring together; R4 represents a linear or branched lower alkyl group having 1-4 carbon atoms or a hydrogen atom; X is a methylene group or a sulfur atom; Y represents a five or six member monocyclic or polycyclic hydrocarbon group, a heterocyclic group having a structure in which one or more carbon atom in the monocyclic or polycyclic hydrocarbon group is replaced by a hetero atom, an aryloxyalkyl group having 12 or less carbon atoms, in which one or more carbon atoms in the monocyclic or polycyclic hydrocarbon group is replaced by a hetero atom, an aryloxyalkyl group having 12 or less carbon atoms, in which the monocyclic or polycyclic hydrocarbon group or the aryloxyalkyl aromatic ring may be substituted with an alkyl group, alkoxy group, ahlogeno group, amino group or hydroxyl group; and Z represents an aliphatic hydrocarbon group having 1-6 carbon atoms or an aromatic hydrocarbon group having 12 or less carbon atoms in which the aromatic ring may be substituted with an alkyl group, alkoxy group, or halogeno group, or one or more carbon atom in the aromatic hydrocarbon group may be replaced by a hetero atom. Also disclosed is the use of said compound in the preparation of an anti-AIDS medicine.
    • 29. 发明专利
    • ES2170962T3
    • 2002-08-16
    • ES97939160
    • 1997-09-03
    • JAPAN ENERGY CORP
    • MATSUZAWA KENJI
    • B01J27/053B01J37/00
    • A molded solid acid catalyst which is used in an isomerization reaction of hydrocarbons and the like, has high activity and excellent strength, and is easy to handle, and a process of preparing the same. This catalyst comprises a carrier comprising tetragonal zirconia and alumina and, supported thereon, a sulfuric acid component and optionally a group 8-10 metal component, wherein the specific surface area of the catalyst is not less than 150 m /g. The catalyst can be prepared by kneading an aluminum hydroxide, a zirconium hydroxide and a compound containing a sulfuric acid component together, molding the mixture, firing the molding at a temperature capable of providing a tetragonal zirconia, and optionally further supporting a group 8-10 metal component and conducting firing at 300 to 700 DEG C.