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21. 发明授权

US06265104B1 Hot-melt seal for metal-air battery 有权
标题翻译：金属空气电池的热熔密封
公开(公告)号：US06265104B1
公开(公告)日：2001-07-24
申请号：US09374278
申请日：1999-08-13
申请人： Matthew Hull , Gary Searle
发明人： Matthew Hull , Gary Searle
IPC分类号： H01M208
CPC分类号： H01M2/08 , H01M12/06 , Y10T29/4911
摘要： A metal-air cell including (a) a container having a positive end and a negative end; (b) a cathode having an end adjacent to the positive end of the container and an end adjacent to the negative end of the container; (c) an anode; (d) a separator between the cathode and the anode; and (e) a seal between the end of the cathode adjacent to the positive end of the container and the positive end of the container is disclosed. The seal includes a hot melt material.
摘要翻译：一种金属空气电池，包括（a）具有正端和负端的容器; （b）具有与容器的正端相邻的端部和与容器的负端相邻的端部的阴极; （c）阳极; （d）阴极和阳极之间的隔膜; 和（e）在与容器的正端相邻的阴极的端部与容器的正端之间的密封件被公开。密封件包括热熔材料。

22. 发明授权

US10029042B2 User-actuated storage assembly for injection device 有权
公开(公告)号：US10029042B2
公开(公告)日：2018-07-24
申请号：US14833965
申请日：2015-08-24
申请人： Gary Searle , Charles Hwang
发明人： Gary Searle , Charles Hwang
IPC分类号： A61M5/32 , A61M5/00
摘要： A storage assembly is removably connectable to a drug delivery device. A first chamber is disposed in the housing. A plurality of penetrating members are stored in the first chamber. A second chamber is disposed in the housing for storing the plurality of penetrating members after being used in an injection. A transfer drum disposed in the housing transfers one of the penetrating members from the first chamber to an injection position and from the injection position to the second chamber following an injection.

23. 发明授权

US09867929B2 Pump engine with metering system for dispensing liquid medication 有权
公开(公告)号：US09867929B2
公开(公告)日：2018-01-16
申请号：US13963748
申请日：2013-08-09
申请人： Gary Searle , Roman Tunkel , William Tormey, III , Andrew Leonczyk , David Pollock , Paul Naumann , Kenneth Focht
发明人： Gary Searle , Roman Tunkel , William Tormey, III , Andrew Leonczyk , David Pollock , Paul Naumann , Kenneth Focht
IPC分类号： A61M5/145 , A61M5/142 , A61M5/168
CPC分类号： A61M5/14244 , A61M5/1452 , A61M5/16809 , A61M5/16881 , A61M2005/16863 , F04C2270/041
摘要： An infusion pump system is disclosed for dispensing liquid medication, such as insulin. The infusion pump system includes a first reservoir for storing liquid medication, a first fluid driver for exerting pressure on the first reservoir, a second reservoir for storing liquid medication, and a second fluid driver for exerting pressure on the second reservoir. One or more valves are used to permit flow of liquid medication from the first reservoir to the second reservoir, and to permit flow of liquid medication from the second reservoir to an infusion site. Each of the valves is selectively opened or closed to fill the second reservoir with liquid medication from the first reservoir and to dispense liquid medication from the second reservoir to the infusion site. A controller and one or more sensors are used to monitor and control the system.

24. 发明授权

US08939928B2 Medical device having capacitive coupling communication and energy harvesting 有权
标题翻译：具有电容耦合通信和能量收集的医疗设备
公开(公告)号：US08939928B2
公开(公告)日：2015-01-27
申请号：US12458807
申请日：2009-07-23
申请人： Richard Savoie , Gary Searle
发明人： Richard Savoie , Gary Searle
IPC分类号： A61M31/00 , A61M5/142 , H04B13/00 , A61M5/172 , A61B5/145 , A61B5/00
CPC分类号： A61M5/14248 , A61B5/0031 , A61B5/14532 , A61B2560/0214 , A61M5/1723 , A61M2205/3538 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/8206 , A61M2205/8212 , A61M2205/8237 , A61M2205/8243 , A61M2205/825 , A61M2205/8256 , A61M2209/01 , A61M2230/201 , A61M2230/63 , H04B13/005
摘要： Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.
摘要翻译：提供了能够经由个人区域网络（PAN）与主机控制器或其他外部设备通信的可穿戴的独立药物输注或医疗设备。该医疗设备利用PAN收发器来通过电容耦合将电流传播穿过用户身体与用户身体（例如生理传感器或主机控制器）接触的通信。医疗装置的可穿戴性质和PAN通信系统的低功率要求使得医疗装置能够利用替代能量收集技术为装置供电。医疗装置优选地在医疗装置的正常使用期间利用热，动能和其他能量收集技术来捕获来自使用者和环境的能量。提供系统配电单元，用于在系统运行期间管理收获的能量并选择性地向医疗装置供电。

25. 发明申请

US20140052096A1 PUMP ENGINE WITH METERING SYSTEM FOR DISPENSING LIQUID MEDICATION 有权
标题翻译：具有用于分配液体药物的计量系统的泵发动机
公开(公告)号：US20140052096A1
公开(公告)日：2014-02-20
申请号：US13963748
申请日：2013-08-09
申请人： Gary Searle , Roman Tunkel , William Tormey III , Andrew Leonczyk , David Pollock , Paul Naumann , Kenneth Focht
发明人： Gary Searle , Roman Tunkel , William Tormey III , Andrew Leonczyk , David Pollock , Paul Naumann , Kenneth Focht
IPC分类号： A61M5/142
CPC分类号： A61M5/14244 , A61M5/1452 , A61M5/16809 , A61M5/16881 , A61M2005/16863 , F04C2270/041
摘要： An infusion pump system is disclosed for dispensing liquid medication, such as insulin. The infusion pump system includes a first reservoir for storing liquid medication, a first fluid driver for exerting pressure on the first reservoir, a second reservoir for storing liquid medication, and a second fluid driver for exerting pressure on the second reservoir. One or more valves are used to permit flow of liquid medication from the first reservoir to the second reservoir, and to permit flow of liquid medication from the second reservoir to an infusion site. Each of the valves is selectively opened or closed to fill the second reservoir with liquid medication from the first reservoir and to dispense liquid medication from the second reservoir to the infusion site. A controller and one or more sensors are used to monitor and control the system.
摘要翻译：公开了用于分配液体药物（例如胰岛素）的输注泵系统。输液泵系统包括用于储存液体药物的第一储存器，用于在第一储存器上施加压力的第一流体驱动器，用于储存液体药物的第二储存器和用于在第二储存器上施加压力的第二流体驱动器。一个或多个阀用于允许液体药物从第一储存器流动到第二储存器，并允许液体药物从第二储存器流动到输注部位。选择性地打开或关闭每个阀，以从第一储存器用液体药物填充第二储存器，并将液体药物从第二储存器分配到输注部位。控制器和一个或多个传感器用于监视和控制系统。

26. 发明申请

US20130046366A1 Patient Heat Transfer Device 审中-公开
标题翻译：病人传热装置
公开(公告)号：US20130046366A1
公开(公告)日：2013-02-21
申请号：US13613937
申请日：2012-09-13
申请人： Francis L. Ross, III , Gary Searle
发明人： Francis L. Ross, III , Gary Searle
IPC分类号： A61F7/00
CPC分类号： A61F7/02 , A61F2007/0018 , A61F2007/0029 , A61F2007/0039 , A61F2007/0054 , A61F2007/0058 , A61F2007/0226 , A61F2007/0231 , A61F2007/0246 , A61F2007/026 , A61F2007/0292 , F28D15/0233 , F28D15/0241 , F28D15/0266 , F28D15/04 , F28D2021/005
摘要： The inventive flexible structure has at least two heat transfer portions. One of heat transfer portions is positioned in contact with the body of the patient. The structure is hermetically sealed and a fluidized medium responsive to temperature change is provided in the structure between the heat transfer portions. The fluid is changeable between a liquid state and a gaseous state, when it is exposed to heat and cold. The heat absorbed by the heat transfer portion in contact with the patient is carried by the fluidized medium, as latent heat in the gas that results when the liquid is vaporized to its gaseous state, to the heat transfer portion layer not in contact with the patient, so that the latent heat in the gaseous vapor is dissipated. Upon dissipation, the gaseous vapor is condensed and the fluidized medium returns to its liquid state.
摘要翻译：本发明的柔性结构具有至少两个传热部分。传热部分之一被定位成与患者的身体接触。该结构是密封的，并且在传热部分之间的结构中提供了响应于温度变化的流化介质。当液体状态和气态暴露于热和冷时，流体是可变的。与患者接触的传热部分吸收的热量由流化介质承载，作为气体中的潜热，当液体蒸发至气态时，其与不与患者接触的传热部分层，使得气体蒸气中的潜热被消散。在消散时，气态蒸汽冷凝，流化介质返回其液态。

27. 发明申请

US20130006216A1 LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD 有权
标题翻译：低剂量预制药物递送装置和方法
公开(公告)号：US20130006216A1
公开(公告)日：2013-01-03
申请号：US13261383
申请日：2011-01-31
申请人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
发明人： Margaret Taylor , James Bates , Roman Tunkel , Jay Butterbrodt , Gary Searle , Joshua Horvath , Keith Knapp, II , Edward Gillen
IPC分类号： A61M5/315 , A61M5/20 , A61M5/32
CPC分类号： A61M5/2425 , A61M5/2459 , A61M5/3287 , A61M5/425 , A61M2005/005 , A61M2005/206
摘要： A drug delivery device (100) for administering a low dose of a medicament includes a housing (111) and a drug reservoir (101) disposed in the housing (111). A needle (135) is connected to the drug reservoir (101). A pressure applying member (113) is movably connected to the housing (111) and is movable between first and second positions. The pressure applying member (113) does not apply pressure to the drug reservoir (101) in the first position and applies pressure to the drug reservoir (101) in the second position to dispense medicament stored in the drug reservoir (101). A method of administering a low dose of insulin to simulate a first-phase insulin response of a pancreas is also disclosed.
摘要翻译：用于施用低剂量药物的药物递送装置（100）包括设置在壳体（111）中的壳体（111）和药物储存器（101）。针（135）连接到药物储存器（101）。压力施加构件（113）可移动地连接到壳体（111）并且可在第一和第二位置之间移动。压力施加构件（113）在第一位置不对药物储存器（101）施加压力，并且在第二位置向药物储存器（101）施加压力以分配存储在药物储存器（101）中的药物。还公开了施用低剂量胰岛素以模拟胰腺的第一阶段胰岛素反应的方法。

28. 发明申请

US20120138165A1 Gas Vent Valve Assembly 审中-公开
标题翻译：排气阀组件
公开(公告)号：US20120138165A1
公开(公告)日：2012-06-07
申请号：US13366431
申请日：2012-02-06
申请人： Eric Andersen , Rene Robert , Gary Searle , Vincent Waldron
发明人： Eric Andersen , Rene Robert , Gary Searle , Vincent Waldron
IPC分类号： F16K49/00
CPC分类号： A61M5/36 , A61F7/0085 , A61M5/385 , A61M5/40 , Y10T137/6416
摘要： A gas vent valve assembly may be attached or incorporated to a disposable fluid transfer set used with a fluid warmer to administer an infusate to a patient. The gas vent valve assembly has a housing having a fluid inlet, a gas outlet and a fluid outlet. The gas outlet is located at the top of the housing while the fluid outlet is located at the bottom of the housing. Inside the housing is an actuator float that has an upper seal and a lower seal. The dimension of the float relative to the chamber of the housing is such that the float is freely movable within the housing to an upper position whereby its upper seal closes the gas outlet while the fluid outlet is opened, and to a lower position whereby its lower seal closes the fluid outlet and the gas outlet is opened.
摘要翻译：气体排出阀组件可以连接或并入到与流体加热器一起使用的一次性流体传送装置，以向患者施用输注物。排气阀组件具有壳体，该壳体具有流体入口，气体出口和流体出口。气体出口位于壳体的顶部，而流体出口位于壳体的底部。外壳内部是一个执行器浮子，具有上密封和下密封。浮体相对于壳体的腔室的尺寸使得浮子可在壳体内自由移动到上部位置，由此其上部密封件在流体出口打开时封闭气体出口，并且在较低位置处其下部密封件关闭流体出口并打开气体出口。

29. 发明申请

US20110054390A1 Extended Use Medical Device 有权
标题翻译：延长使用医疗器械
公开(公告)号：US20110054390A1
公开(公告)日：2011-03-03
申请号：US12585061
申请日：2009-09-02
申请人： Gary Searle , Keith N. Knapp , Roman Tunkel , Peter Skutnik , Lionel Vedrine
发明人： Gary Searle , Keith N. Knapp , Roman Tunkel , Peter Skutnik , Lionel Vedrine
IPC分类号： A61M5/168 , A61M5/142
CPC分类号： A61M5/158 , A61M5/1413 , A61M5/14212 , A61M5/14224 , A61M5/14248 , A61M5/16886 , A61M5/1723 , A61M5/3134 , A61M5/385 , A61M5/46 , A61M2005/14208 , A61M2005/14268 , A61M2005/1585 , A61M2005/16872 , A61M2205/16 , A61M2205/702 , A61M2209/045 , A61M2230/005 , A61M2230/201
摘要： Provided is an extended use self-contained, wearable medical device. The device is preferably configured with an infusion deployment mechanism for variably inserting and retracting an infusion needle to different depths, or completely retracting the infusion needle from the infusion site and then re-inserting the infusion needle after a predetermined period of time, throughout an infusion cycle for extending the viability of the infusion site. Another embodiment comprises dual needle deployment mechanisms which may also variably insert and retract the infusion needles. A flow sensor is preferably provided for detecting the stoppage of flow through the infusion cannula and signaling the needle deployment mechanism to attempt infusion at a different depth or to deploy a second infusion needle. A re-fillable reservoir assembly is preferably provided for supplying a drug over the extended use of the device. Another embodiment comprises a partially reusable and partially disposable medical device implementing the above features.
摘要翻译：提供了一种扩展使用的独立的，可穿戴的医疗设备。该装置优选地配置有输注展开机构，用于将输注针可变地插入和缩回到不同的深度，或者将输注针从输注部位完全缩回，然后在整个输注期间在预定时间段之后重新插入输注针循环，以延长输注部位的生存能力。另一个实施例包括双针展开机构，其也可以可变地插入和缩回输注针。优选地设置流量传感器，用于检测通过输注套管的流动的停止并且发出针部署机构以尝试在不同深度输注或部署第二输注针。优选地，可重新填充的储存器组件用于通过扩展使用该装置来供应药物。另一实施例包括实现上述特征的部分可再利用和部分一次性医疗装置。

30. 发明申请

US20110022025A1 Medical device having capacitive coupling communication and energy harvesting 有权
标题翻译：具有电容耦合通信和能量收集的医疗设备
公开(公告)号：US20110022025A1
公开(公告)日：2011-01-27
申请号：US12458807
申请日：2009-07-23
申请人： Richard Savoie , Gary Searle
发明人： Richard Savoie , Gary Searle
IPC分类号： A61M5/172 , A61M5/142
CPC分类号： A61M5/14248 , A61B5/0031 , A61B5/14532 , A61B2560/0214 , A61M5/1723 , A61M2205/3538 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/52 , A61M2205/8206 , A61M2205/8212 , A61M2205/8237 , A61M2205/8243 , A61M2205/825 , A61M2205/8256 , A61M2209/01 , A61M2230/201 , A61M2230/63 , H04B13/005
摘要： Provided is a wearable, self-contained drug infusion or medical device capable of communicating with a host controller or other external devices via a personal area network (PAN). The medical device utilizes a PAN transceiver for communication with other devices in contact with a user's body, such as a physiological sensor or host controller, by propagating a current across the user's body via capacitive coupling. The wearable nature of the medical device and the low power requirements of the PAN communication system enable the medical device to utilize alternative energy harvesting techniques for powering the device. The medical device preferably utilizes thermal, kinetic and other energy harvesting techniques for capturing energy from the user and the environment during normal use of the medical device. A system power distribution unit is provided for managing the harvested energy and selectively supplying power to the medical device during system operation.
摘要翻译：提供了能够经由个人区域网络（PAN）与主机控制器或其他外部设备通信的可穿戴的独立药物输注或医疗设备。该医疗设备利用PAN收发器来通过电容耦合将电流传播穿过用户身体与用户身体（例如生理传感器或主机控制器）接触的通信。医疗装置的可穿戴性质和PAN通信系统的低功率要求使得医疗装置能够利用替代能量收集技术为装置供电。医疗装置优选地在医疗装置的正常使用期间利用热，动能和其他能量收集技术来捕获来自使用者和环境的能量。提供系统配电单元，用于在系统运行期间管理收获的能量并选择性地向医疗装置供电。

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