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    • 21. 发明申请
    • TRAINING A MODEL OF A NON-LINEAR PROCESS
    • 培养非线性过程的模型
    • US20080235166A1
    • 2008-09-25
    • US12112750
    • 2008-04-30
    • Bijan Sayyar-RodsariEdward PlumerEric HartmanKadir LianoCelso Axelrud
    • Bijan Sayyar-RodsariEdward PlumerEric HartmanKadir LianoCelso Axelrud
    • G06F15/18
    • G05B13/048G05B13/042G05B17/02
    • System and method for modeling a nonlinear process. A combined model for predictive optimization or control of a nonlinear process includes a nonlinear approximator, coupled to a parameterized dynamic or static model, operable to model the nonlinear process. The nonlinear approximator receives process inputs, and generates parameters for the parameterized dynamic model. The parameterized dynamic model receives the parameters and process inputs, and generates predicted process outputs based on the parameters and process inputs, where the predicted process outputs are useable to analyze and/or control the nonlinear process. The combined model may be trained in an integrated manner, e.g., substantially concurrently, by identifying process inputs and outputs (I/O), collecting data for process I/O, determining constraints on model behavior from prior knowledge, formulating an optimization problem, executing an optimization algorithm to determine model parameters subject to the determined constraints, and verifying the compliance of the model with the constraints.
    • 用于建模非线性过程的系统和方法。 用于非线性过程的预测优化或控制的组合模型包括耦合到参数化动态或静态模型的非线性近似器,可操作以对非线性过程建模。 非线性近似器接收过程输入,并为参数化动态模型生成参数。 参数化动态模型接收参数和过程输入,并根据参数和过程输入生成预测过程输出,其中预测过程输出可用于分析和/或控制非线性过程。 组合模型可以通过识别过程输入和输出(I / O),收集过程I / O的数据,确定来自先验知识的模型行为的约束,制定优化问题,以基本上同时的方式进行训练, 执行优化算法以确定受限于确定的模型参数,并验证模型与约束的一致性。
    • 24. 发明申请
    • Laterally-actuated dispenser with one-way valve for storing and dispensing metered amounts of substances
    • 具有用于存储和分配计量的物质的单向阀的侧向致动的分配器
    • US20060065677A1
    • 2006-03-30
    • US11237599
    • 2005-09-27
    • Daniel PyJulian ChanDavid FellowsEric HartmanBing He
    • Daniel PyJulian ChanDavid FellowsEric HartmanBing He
    • B67D5/40
    • B65D83/0094A45D34/04A45D2200/055A45D2200/056A61M35/003B05B11/00416B05B11/3015B05B11/3032B05B11/3033B05B11/3094B65B1/04B65D83/0033G01F11/025G01F11/08
    • A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body defining a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and defines a bore coupled in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the bore. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser. The dispenser further comprises an actuator and piston assembly including a piston receivable within the bore, a manually-engageable actuator connected to the piston for moving the piston between first and second positions relative to the bore to dispense substance within the bore through the outlet aperture, and an integral, dome-shaped spring coupled to at least one of the piston and the actuator for biasing the piston in a direction from one of the first and second positions toward the other.
    • 用于分配物质(例如药物,眼科,皮肤病学,药妆,化妆品或其他产品)的分配器具有限定用于存储产品的可变容积储存室的主体。 分配器的分配部分与主体连接并且限定了与储存室流体连通以接收物质的孔以及与孔流体连通的出口孔。 分配器的单向阀包括轴向延伸的阀座和位于阀座上的轴向延伸的柔性阀盖,并且在其间限定一个常闭的轴向延伸的接缝,形成在阀盖之间的流体密封 和阀座。 柔性阀盖可相对于阀座移动,并且接缝可与出口孔流体连通以允许物质通过接缝并从分配器中通过。 分配器还包括致动器和活塞组件,其包括可接收在孔内的活塞,连接到活塞的可手动接合的致动器,用于相对于孔移动活塞在第一和第二位置之间,以通过出口孔分配孔内的物质, 以及联接到所述活塞和所述致动器中的至少一个的整体的圆顶形弹簧,用于沿从所述第一位置和所述第二位置之一向另一个方向偏压所述活塞。
    • 25. 发明申请
    • Parametric universal nonlinear dynamics approximator and use
    • 参数通用非线性动力学近似和使用
    • US20050187643A1
    • 2005-08-25
    • US10842157
    • 2004-05-10
    • Bijan Sayyar-RodsariEdward PlumerEric HartmanKadir LianoCelso Axelrud
    • Bijan Sayyar-RodsariEdward PlumerEric HartmanKadir LianoCelso Axelrud
    • G05B13/02G05B13/04G05B17/02G06F15/18
    • G05B13/048G05B13/042G05B17/02
    • System and method for modeling a nonlinear process. A combined model for predictive optimization or control of a nonlinear process includes a nonlinear approximator, coupled to a parameterized dynamic or static model, operable to model the nonlinear process. The nonlinear approximator receives process inputs, and generates parameters for the parameterized dynamic model. The parameterized dynamic model receives the parameters and process inputs, and generates predicted process outputs based on the parameters and process inputs, where the predicted process outputs are useable to analyze and/or control the nonlinear process. The combined model may be trained in an integrated manner, e.g., substantially concurrently, by identifying process inputs and outputs (I/O), collecting data for process I/O, determining constraints on model behavior from prior knowledge, formulating an optimization problem, executing an optimization algorithm to determine model parameters subject to the determined constraints, and verifying the compliance of the model with the constraints.
    • 用于建模非线性过程的系统和方法。 用于非线性过程的预测优化或控制的组合模型包括耦合到参数化动态或静态模型的非线性近似器,可操作以对非线性过程建模。 非线性近似器接收过程输入,并为参数化动态模型生成参数。 参数化动态模型接收参数和过程输入,并根据参数和过程输入生成预测过程输出,其中预测过程输出可用于分析和/或控制非线性过程。 组合模型可以通过识别过程输入和输出(I / O),收集过程I / O的数据,确定来自先验知识的模型行为的约束,制定优化问题,以基本上同时的方式进行训练, 执行优化算法以确定受限于确定的模型参数,并验证模型与约束的一致性。