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11. 发明授权

US06443912B1 Method and apparatus for catheter exchange by guide wire-captivation 失效
标题翻译：通过引导线捕获导管交换的方法和装置
公开(公告)号：US06443912B1
公开(公告)日：2002-09-03
申请号：US07789183
申请日：1991-11-08
申请人： Christian L. Mazzola , Peter T. Keith , Daniel O. Adams
发明人： Christian L. Mazzola , Peter T. Keith , Daniel O. Adams
IPC分类号： A61M2902
CPC分类号： A61M25/0105 , A61M2025/0098
摘要： An apparatus for exchanging over-the-wire balloon catheters engages a guide wire within a guide catheter. In one embodiment the engagement is by an inflatable balloon in the guide catheter. Alternatively, the engagement is accomplished by a captivation wire in the guide catheter that has a collapsible loop portion through which the guide wire extends. Inflation of the balloon or closing the loop portion of the captivation wire within the guide catheter traps the guide wire and restricts its movement relative to the guide catheter. Once the guide wire position is fixed, withdrawal of a first balloon catheter and subsequent introduction of a second balloon catheter over the guide wire is possible without moving the guide wire longitudinally. Thus, the positioning of the guide wire over a stenosis to be dilated is not disturbed.
摘要翻译：用于更换线上气球导管的装置与导向导管内的导丝接合。在一个实施例中，接合是通过引导导管中的可充气气囊。或者，通过引导导管中的捕捉线实现接合，该引导导管具有导丝延伸穿过的可折叠环部分。引导导管中的气囊充气或闭合吸引线的环部分会捕获导丝并限制其相对于导向导管的运动。一旦引导线位置固定，就可以在不使导丝纵向移动的情况下取出第一气囊导管并且随后将第二气囊导管引导到引导线上。因此，引导线在狭窄处的扩张定位不会受到干扰。

12. 发明授权

US06309339B1 Intravascular radiation delivery device 失效
标题翻译：血管内辐射输送装置
公开(公告)号：US06309339B1
公开(公告)日：2001-10-30
申请号：US09118308
申请日：1998-07-16
申请人： Jay P Ciezki , Eugene J. Jung, Jr. , Eric J. Lee , Emin M. Tuzcu , James D. Savage , Martin S. Weinhous
发明人： Jay P Ciezki , Eugene J. Jung, Jr. , Eric J. Lee , Emin M. Tuzcu , James D. Savage , Martin S. Weinhous
IPC分类号： A61M2902
CPC分类号： A61N5/1002 , A61N2005/1005
摘要： A device and method for precisely delivering dosage of radiation from a radiation source to a treatment site of a vessel is provided herein. In one embodiment, the device includes a catheter which inserts into a vessel lumen of the body. The catheter includes an adjuster section for altering a portion of the radiation emitting radially from the radiation source so that the radiation source delivers an asymmetrical radiation profile to the vessel. The device can also include a catheter supporter which inhibits rotational deformation in the catheter between a catheter distal end and a catheter proximal end. This allows the delivery section to be precisely rotated to properly position the adjuster section within the vessel lumen.
摘要翻译：本文提供了一种用于将辐射源的辐射剂量准确地输送到容器的处理部位的装置和方法。在一个实施例中，该装置包括插入身体的血管腔的导管。导管包括调节器部分，用于改变从辐射源径向辐射的辐射的一部分，使得辐射源将不对称辐射轮廓传送到血管。该装置还可以包括导管支撑件，其阻止导管在导管远端和导管近端之间的旋转变形。这允许输送部分被精确地旋转以将调节器部分适当地定位在血管内腔内。

13. 发明授权

US06248122B1 Catheter with controlled release endoluminal prosthesis 失效
标题翻译：导管与控制释放内腔假体
公开(公告)号：US06248122B1
公开(公告)日：2001-06-19
申请号：US09258542
申请日：1999-02-26
申请人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar
发明人： Katherine J. Klumb , Thomas J. Fogarty , Kirti P. Kamdar
IPC分类号： A61M2902
CPC分类号： A61F2/958 , A61F2/07 , A61F2/88 , A61F2/954 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/9511 , A61F2002/9517 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2250/0018 , A61F2250/0039
摘要： A catheter (4) includes a hollow catheter shaft (18), an inflatable balloon (36) surrounding the catheter shaft distal portion, and an expandable endoluminal prosthesis, such as a stent graft (38, 40), surrounding the balloon. The stent is typically a coiled stent having distal ends (58, 48) slidably housed within stent end holders (56, 50) on the catheter shaft. The first stent end is released from its holder by inflating the balloon. The second stent end is selectively released from its holder by other than inflating the balloon, typically by a push wire (30) pushing the second stent end out of its holder. A sheath (8) is moveable between a first position surrounding the stent and a second position spaced-apart from the stent. The stent is prevented from assuming its expanded-diameter state by (1) the engagement of the stent ends with the catheter shaft through the stent end holders, and (2) the sheath being in its first position during the introducing step. The stent may be a straight stent (3 8) or a bifurcated stent (38D).
摘要翻译：导管（4）包括中空的导管轴（18），围绕导管轴远端部分的可膨胀气囊（36）和围绕气囊的可扩张的腔内假体，例如支架移植物（38,40）。支架通常是具有可滑动地容纳在导管轴上的支架端部保持器（56,50）内的远端（58,48）的盘绕支架。通过使气囊膨胀，第一个支架端从其支架释放。通常通过将第二支架端部推出其保持器的推动线（30）来使第二支架端部从其保持器选择性地释放，除了使气囊膨胀。护套（8）可以在围绕支架的第一位置和与支架间隔开的第二位置之间移动。通过（1）支架端部与导管轴通过支架端部保持器接合，防止支架呈现其扩径状态，以及（2）在引入步骤期间护套处于其第一位置。支架可以是直支架（38）或分叉支架（38D）。

14. 发明授权

US06663660B2 Stent delivery system having stent securement apparatus 失效
标题翻译：支架输送系统具有支架固定装置
公开(公告)号：US06663660B2
公开(公告)日：2003-12-16
申请号：US09794648
申请日：2001-02-27
申请人： Andrew J. Dusbabek , Louis G. Ellis , Christopher R. Larson , Terry V. Brown , Charles L. Euteneuer , Steven P. Mertens , Richard C. Mattison , David J. Blaeser , Linda R. Lorentzen Cornelius , Martin R. Willard , Fernando Di Caprio , Stanley A. Nordin
发明人： Andrew J. Dusbabek , Louis G. Ellis , Christopher R. Larson , Terry V. Brown , Charles L. Euteneuer , Steven P. Mertens , Richard C. Mattison , David J. Blaeser , Linda R. Lorentzen Cornelius , Martin R. Willard , Fernando Di Caprio , Stanley A. Nordin
IPC分类号： A61M2902
CPC分类号： A61F2/958 , A61F2002/9522 , A61F2002/9583 , A61F2002/9586 , A61M25/1011 , A61M25/10184 , A61M25/10186 , A61M25/104 , A61M2025/1013 , A61M2025/1063 , A61M2025/1079 , A61M2025/1081 , A61M2025/1093
摘要： A system/assembly for delivery and deployment of an inflation expandable stent within a vessel, comprising a catheter having proximal and distal ends; a stent, inflation expandable from a delivery diameter to a deployment diameter, such that the delivery diameter is reduced from the deployment diameter for conforming the stent to the catheter, such that the stent, in its delivery diameter, is coaxially mounted on the catheter near the catheter distal end; an expandable inflation means coaxially mounted on the catheter axially within the stent, for expansion of the stent from the delivery diameter to the deployment diameter upon application of fluid deployment pressure to the inflation means; and a securement component coaxially mounted on the catheter, axially within the expandable inflation means, the securement component designed and adapted to provide a securement pressure to the stent in the delivery diameter to maintain the stent in position on the catheter during delivery to the deployment site.
摘要翻译：一种用于在容器内递送和展开膨胀扩张支架的系统/组件，包括具有近端和远端的导管; 支架，膨胀从输送直径扩展到展开直径，使得输送直径从展开直径减小，以使支架与导管吻合，使得支架在其输送直径中同轴地安装在导管附近导管远端; 可扩张的膨胀装置同轴地安装在支架内轴向的导管上，用于在向通气装置施加流体展开压力时将支架从输送直径扩展到展开直径; 以及固定组件，其轴向地同轴地安装在导管上，在可膨胀的充气装置内，固定部件设计和适于在输送直径中向支架提供固定压力，以在输送到展开部位期间将支架维持在导管上的适当位置。

15. 发明授权

US06585633B2 Brachytherapy seed cartridge 有权
标题翻译：近距离放射治疗种子筒
公开(公告)号：US06585633B2
公开(公告)日：2003-07-01
申请号：US09779993
申请日：2001-02-09
申请人： Dario Vitali , Thomas J. Sierocuk , Kip M. Rupp , Scott N. Barton , Michael A. Colbert , Gregory D. Bishop , David H. Ruder
发明人： Dario Vitali , Thomas J. Sierocuk , Kip M. Rupp , Scott N. Barton , Michael A. Colbert , Gregory D. Bishop , David H. Ruder
IPC分类号： A61M2902
CPC分类号： A61N5/1007 , A61N5/1027 , A61N2005/101
摘要： The present invention is directed to a seed cartridge assembly including a cartridge body, a seed drawer slideably disposed within the cartridge body, a radiation shield slideably disposed around the cartridge body and a seed retainer in the seed drawer. Further embodiments of the present invention include a seed cartridge assembly as described above including a gravity lock between the seed drawer and the cartridge body. Further embodiments of the present invention include a seed cartridge assembly as described above, wherein the cartridge body includes a magnification lens positioned above the seed drawer. Further embodiments of the present invention include a seed cartridge assembly as described above wherein a seed channel extends axially along the seed drawer and a plurality of vents extending from the seed channel to an exterior surface of the seed drawer. Further embodiments of the present invention include a seed cartridge assembly as described above wherein the gravity lock includes a moveable locking element, a first locking recess in an interior surface of the cartridge body and a second locking recess in an exterior surface of the drawer opposite the first locking recess.
摘要翻译：本发明涉及一种种子盒组件，其包括盒体，可滑动地设置在盒体内的种子抽屉，可滑动地设置在盒体周围的辐射屏蔽和种子抽屉中的种子保持器。本发明的另外的实施例包括如上所述的种子仓组件，其包括种子抽屉和盒体之间的重力锁。本发明的其他实施例包括如上所述的种子盒组件，其中盒体包括位于种子抽屉上方的放大镜。本发明的另外的实施例包括如上所述的种子盒组件，其中种子通道沿着种子抽屉轴向延伸，并且多个通孔从种子通道延伸到种子抽屉的外表面。本发明的另外的实施例包括如上所述的种子盒组件，其中重力锁包括可移动的锁定元件，在盒主体的内表面中的第一锁定凹部和与抽屉相对的抽屉的外表面中的第二锁定凹部第一锁定凹槽。

16. 发明授权

US06575934B2 Low profile catheter 有权
公开(公告)号：US06575934B2
公开(公告)日：2003-06-10
申请号：US09746416
申请日：2000-12-21
申请人： Jacky G. Duchamp
发明人： Jacky G. Duchamp
IPC分类号： A61M2902
CPC分类号： A61M25/1034 , A61M2025/1063 , A61M2025/1093
摘要： The invention is directed to an intravascular balloon catheter and a method for forming the same. The catheter includes an elongated shaft having proximal and distal ends, a guidewire receiving lumen extending through at least a distal portion of the elongated shaft; and a balloon on a distal shaft section. A distal portion the guidewire receiving lumen has different stiffness along a length thereof.

17. 发明授权

US06527790B2 Intravascular balloon catheter for embolic coil delivery 有权
公开(公告)号：US06527790B2
公开(公告)日：2003-03-04
申请号：US09732476
申请日：2000-12-07
申请人： Thomas Yung-Hui Chien , Greg P. Welsh , Huey Quoc Chan
发明人： Thomas Yung-Hui Chien , Greg P. Welsh , Huey Quoc Chan
IPC分类号： A61M2902
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12145 , A61B90/39 , A61B2017/00557 , A61B2017/1205 , A61B2017/22052 , A61B2017/22068 , A61B2017/22069
摘要： Improved intravascular balloon catheters for the delivery of embolic agents and devices such as coils to wide-neck aneurysms. In one embodiment, the present invention provides a balloon catheter having a combined guide wire/delivery lumen and a lateral delivery hole. The balloon may comprise a multi-lobed design with the delivery hole disposed between adjacent balloon lobes. The balloon catheter preferably includes a diversion member disposed in the combined lumen to cause the embolic device to divert from the combined lumen, through the delivery hole, and into the wide-neck aneurysm. In another embodiment, the present invention provides a balloon catheter having a shaft including a shaft tube and a co-extending embolic delivery tube. The delivery tube terminates proximal of the distal end of the shaft tube for added flexibility, and the balloon may inflate eccentrically to push the distal opening of the delivery lumen adjacent the opening of the wide-neck aneurysm.

18. 发明授权

US06451042B1 Method and apparatus for dissecting tissue layers 失效
标题翻译：用于解剖组织层的方法和装置
公开(公告)号：US06451042B1
公开(公告)日：2002-09-17
申请号：US09225952
申请日：1999-01-06
申请人： Peter M. Bonutti
发明人： Peter M. Bonutti
IPC分类号： A61M2902
CPC分类号： A61B17/0218 , A61B17/02 , A61B17/025 , A61B17/320036 , A61B17/320725 , A61B17/3417 , A61B2017/00535 , A61B2017/00539 , A61B2017/00557 , A61B2017/00986 , A61B2017/0256 , A61B2017/320048 , A61B2017/3484 , A61B2090/062 , A61M25/1002 , A61M2025/006
摘要： A retractor for use in arthroscopic surgery. The retractor has a mechanical expanding portion for expanding against sub-surface tissues when the retractor is in use. The retractor also has a fluid-operated expanding portion, which may be independently controllable, for expanding against sub-surface tissues when the retractor is in use. The retractor is inserted through a small percutaneous opening, expanded in sub-surface tissues without significantly damaging the tissue, then collapsed after use for removal. The retractor can be manipulated to allow the surgeon to push or pull or lever on tissue. The retractor can be hollow like a cannula to permit the passage of one or more surgical devices through the retractor, with a side portal into the center of the retractor.
摘要翻译：用于关节镜手术的牵开器。牵开器具有机械扩张部分，用于当卷收器在使用时用于对着表面下的组织扩张。牵开器还具有流体操作的膨胀部分，该部分可以是独立可控的，用于在牵开器使用时向下表面组织扩张。牵开器通过小的经皮开口插入，在亚表面组织中扩张而不会显着损伤组织，然后在使用后塌陷以便移除。可以操纵牵开器以允许外科医生将组织推或拉。牵开器可以像套管一样是中空的，以允许一个或多个手术装置通过牵开器，侧入口进入牵开器的中心。

19. 发明授权

US06379365B1 Stent delivery catheter system having grooved shaft 有权
标题翻译：支架输送导管系统具有沟槽轴
公开(公告)号：US06379365B1
公开(公告)日：2002-04-30
申请号：US09336206
申请日：1999-06-18
申请人： Alexis Diaz
发明人： Alexis Diaz
IPC分类号： A61M2902
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A stent delivery system for medical treatment of a patient includes a balloon catheter, a stent, a sheath, and a flexible tapered introducer tip. The balloon catheter has a hub, shaft, and inflatable balloon, as well as a tubular stent mounted about the deflated balloon and crimped to an initial diameter. The introducer tip is affixed to the distal end of the balloon catheter and tapers to a maximum outer diameter equal to the crimped stent outer diameter plus the sheath wall thickness. The balloon catheter shaft defines a groove along a major portion of its length, in which a guidewire may be partially received or embedded. This grooved design enables the stent delivery system shaft to have a smaller diameter. The composite sheath has a multiple diameter design with a distal portion adapted to retractably cover the crimped stent, and a proximal portion having a smaller diameter. This smaller diameter enables greater flow of a radiopaque contrast fluid around the outside of the proximal sheath and through the inside of a guiding catheter, thus providing the system with a high visibility capability. The introducer tip defines a shoulder against which the sheath can push in a distal direction, assisting the stent delivery system to perform primary stent delivery without a preliminary angioplasty procedure.
摘要翻译：用于医疗病人的支架输送系统包括球囊导管，支架，护套和柔性锥形导引器尖端。气囊导管具有轮毂，轴和可膨胀气囊，以及围绕放气球囊安装并卷曲成初始直径的管状支架。引导器末端固定在球囊导管的远端，并且逐渐变细至最大外径等于卷曲支架外径加上鞘壁厚度。气囊导管轴沿其长度的主要部分限定一个槽，其中可以部分地接收或嵌入导丝。这种带槽设计使得支架输送系统轴具有更小的直径。复合护套具有多径设计，其具有适于可收缩地覆盖卷曲支架的远侧部分和具有较小直径的近端部分。这种更小的直径使得不透射线的对比流体能够在近侧护套的外部和导向导管的内部更大地流动，从而为系统提供高可见性能力。引导器末端限定肩部，护套可以在该肩部沿远侧方向推动，辅助支架输送系统执行主支架输送，而无需初步血管成形术程序。

20. 发明授权

US06358266B1 Active cannulas 失效
标题翻译：活动插管
公开(公告)号：US06358266B1
公开(公告)日：2002-03-19
申请号：US08727968
申请日：1996-10-09
申请人： Peter M. Bonutti
发明人： Peter M. Bonutti
IPC分类号： A61M2902
CPC分类号： A61M29/02 , A61B17/02 , A61B17/0218 , A61B17/025 , A61B17/320036 , A61B17/320725 , A61B17/3421 , A61B17/3439 , A61B2017/00535 , A61B2017/00557 , A61B2017/0256 , A61B2017/320048 , A61B2017/3486 , A61B2090/062 , A61M25/06 , A61M25/1002 , A61M2025/006
摘要： An active cannula or sleeve which does more than merely maintain a channel or passage is usable to create and/or enlarge a channel or passage, to position a scope or instrument, to move or locate tissue, etc. The cannula can vary in size or shape as needed, intraoperatively. Because a cannula of the present invention is expandable, the surgeon can make a small relatively small incision, stretch the tissue with the expandable cannula, contract the cannula and remove it, allowing the skin to come back to its unstretched condition. Thus, a smaller incision can be made to fit the same size instrument. This results in less trauma and scarring and an easier operation. The cannulas are or can assume such a non-circular shape, to fit into a natural skin opening and cause less trauma. The devices can be used to seal off a space; to expand an existing space or a potential space for working or visualization; to move tissue (for example, to stretch an incision) or to protect it.
摘要翻译：不仅仅保持通道或通道的主动插管或套管可用于产生和/或扩大通道或通道，以定位一个或多个器械来移动或定位组织等。套管的尺寸可以变化根据需要进行手术。因为本发明的插管是可扩张的，所以外科医生可以进行小的相对小的切口，用可扩张插管拉伸组织，收缩插管并将其移除，从而允许皮肤回到其未拉伸状态。因此，可以进行较小的切口以适合相同尺寸的仪器。这导致较少的创伤和瘢痕形成，并且更容易操作。插管是或可以采取这样的非圆形形状，以适应自然的皮肤开放并且引起较少的创伤。这些设备可用于密封空间; 扩大现有空间或潜在的工作空间或可视化空间; 移动组织（例如，拉伸切口）或保护它。

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