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11. 发明申请

US20020076451A1 Health food products 有权
标题翻译：保健食品
公开(公告)号：US20020076451A1
公开(公告)日：2002-06-20
申请号：US09828798
申请日：2001-04-10
申请人： DAICHO KIKAKU INCORPORATED COMPANY
发明人： Takao Daicho
IPC分类号： A61K035/78 , A61K031/7048
CPC分类号： A61K31/575 , A23L33/105 , A23V2002/00 , A61K36/23 , A61K36/258 , A61K36/284 , A61K36/31 , A61K36/344 , A61K36/36 , A61K36/48 , A61K36/481 , A61K36/484 , A61K36/725 , A61K36/734 , A61K36/8945 , A61K36/8969 , A61K36/899 , A61K31/35 , A61K2300/00 , A23V2250/304 , A23V2250/2116 , A23V2250/21 , A23V2250/70
摘要： An object of the present invention is to provide a very effective health food exhibiting the effect near that which has been already achieved by the traditional Chinese medical science. The present invention relates to a health food product comprising cholic acid, especially to a health food product comprising cholic acid and isoflavone and/or isoflavone glycoside.
摘要翻译：本发明的目的是提供一种非常有效的保健食品，其表现出接近中国传统医学已经实现的效果。本发明涉及包含胆酸的保健食品，特别涉及包含胆酸和异黄酮和/或异黄酮糖苷的保健食品。

12. 发明申请

US20020009423A1 Methods for managing scalp conditions 有权
标题翻译：头皮条件管理方法
公开(公告)号：US20020009423A1
公开(公告)日：2002-01-24
申请号：US09920729
申请日：2001-08-03
发明人： Howard Murad
IPC分类号： A61K007/06 , A61K007/11
CPC分类号： A61Q5/02 , A61K8/345 , A61K8/365 , A61K8/4946 , A61K8/602 , A61K8/671 , A61K8/675 , A61K8/97 , A61K31/58 , A61K31/60 , A61K31/70 , A61K36/36 , A61K36/889 , A61K45/06 , A61K2800/782 , A61Q5/006 , A61Q7/00 , Y10S514/88 , Y10S514/881 , A61K2300/00
摘要： This application relates to a pharmaceutical composition for the prevention, treatment, and management of scalp conditions, such as dandruff, seborrheic dermatitis, psoriasis, folliculitis, and hair thinning including a therapeutically effective amount of an acidic component of a hydroxyacid or tannic acid, or a pharmaceutically acceptable salt thereof. A preferred anti-dandruff composition and method of managing dandruff includes a therapeutically effective amount of the acid component, a vitamin A component, and an anti-growth agent. A preferred anti-hair thinning composition and method of managing thinning hair includes a therapeutically effective amount of the acidic component, a niacin component present in an amount sufficient to locally increase blood circulation, and a 5-null reductase inhibitor. The invention also relates to a method of treating chemically processed hair by administering to a patient an amount of an acidic component of a hydroxy acid or tannic acid, or a pharmaceutically acceptable salt thereof, in an amount sufficient to essentially close the cuticle and inhibit modification of the chemically processed hair.
摘要翻译：本申请涉及用于预防，治疗和管理头皮状况的药物组合物，例如头皮屑，脂溢性皮炎，牛皮癣，毛囊炎和头发变薄，包括治疗有效量的酸性组分的羟基酸或丹宁酸，或其药学上可接受的盐。优选的去头皮屑组合物和头皮屑的治疗方法包括治疗有效量的酸组分，维生素A组分和抗生长剂。优选的抗毛发稀疏组合物和管理稀释毛发的方法包括治疗有效量的酸性组分，以足以局部增加血液循环的量存在的烟酸组分和5-α还原酶抑制剂。本发明还涉及一种通过向患者施用一定量的羟基酸或丹宁酸的酸性组分或其药学上可接受的盐，其量足以基本上封闭角质层并抑制修饰，从而处理化学处理的毛发的化学处理毛发。

13. 发明专利

JP2017518381A 瓦草５環性トリテルペンサポニン類化合物抗腫瘍の薬物用途有权
公开(公告)号：JP2017518381A
公开(公告)日：2017-07-06
申请号：JP2017518396
申请日：2015-06-15
申请人：学勇王 , 学勇王 , 保勝趙 , 保勝趙
发明人：学勇王 , 学勇王 , 保勝趙 , 保勝趙
IPC分类号： A61K31/704 , A61K9/08 , A61K9/16 , A61K9/20 , A61K9/48 , A61K31/513 , A61K31/675 , A61K45/00 , A61P1/04 , A61P1/16 , A61P15/00 , A61P17/00 , A61P35/00
CPC分类号： A61K31/704 , A61K31/337 , A61K31/513 , A61K31/675 , A61K35/00 , A61K36/36 , A61K2300/00
摘要：本発明は、式Iの構造の化合物又はその塩、及び該化合物を含む総サポニン類成分の抗腫瘍薬物の調製における使用の一種を提供する。本発明の研究によると、式Iの化合物及び総サポニンが、ヒト肝臓癌細胞、ヒト胃癌細胞、ヒト大腸癌細胞、ヒト乳腺癌細胞及び黒色素腫瘍細胞株の全ての増長に対して強い抑制効果を有し、且つ式Iの化合物及び化学療法薬物を併用すると良好に副作用が低減され、効果が増強されることが示されている。【選択図】なし

14. 发明专利

JP2011521982A Composition for the treatment of diseases of the upper respiratory tract and influenza syndromes 有权
公开(公告)号：JP2011521982A
公开(公告)日：2011-07-28
申请号：JP2011512001
申请日：2009-05-25
申请人：インデナエッセピア
发明人：エッツィオボンバルデッリ、
IPC分类号： A61K31/4355 , A61K9/06 , A61K9/08 , A61K9/20 , A61K9/68 , A61K31/366 , A61K36/00 , A61K36/18 , A61K36/28 , A61P11/00 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/16
CPC分类号： A61K36/36 , A61K31/473 , A61K36/185 , A61K36/28
摘要： The present invention relates to compositions based on benzophenanthridine alkaloids, extract of Hippophae rhamnoides and extract of Echinacea angustifolia which possess antibacterial, antiviral and anti-inflammatory activity, and are useful in the treatment of bacterial and viral infections of the upper respiratory tract, and in the treatment of influenza.

15. 发明专利

JP2004067660A TYPE 2 OR TYPE 3 HUMAN β-DEFENSIN-STIMULATING ACTIVE COMPONENT, AND COSMETIC AND MEDICINAL COMPOSITION CONTAINING THE SAME 有权
公开(公告)号：JP2004067660A
公开(公告)日：2004-03-04
申请号：JP2003006735
申请日：2003-01-15
申请人： Coletica , Ysl Beaute , コレティカColetica , ワイエスエル・ボーテYsl Beaute
发明人： PERRIER ERIC , GUEZENNEC ANNE , PERNET INGRID , REYMERNIER CORINNE , GUESNET JOELLE
IPC分类号： A61K8/30 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/365 , A61K8/44 , A61K8/64 , A61K8/67 , A61K8/96 , A61K8/97 , A61K31/07 , A61K31/19 , A61K31/198 , A61K31/223 , A61K33/06 , A61K36/00 , A61K36/18 , A61K36/28 , A61K36/42 , A61K36/53 , A61K38/00 , A61K38/02 , A61K38/16 , A61K38/34 , A61K39/00 , A61K45/00 , A61P17/00 , A61P17/04 , A61P31/04 , A61P31/10 , A61P43/00 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , C12N5/08 , C12Q1/02 , C12Q1/25 , C12Q1/68 , G01N33/50 , A61K7/00 , A61K7/02 , A61K7/06 , A61K7/075 , A61K7/48 , A61K35/78
CPC分类号： A61K8/97 , A61K8/36 , A61K8/365 , A61K8/44 , A61K8/64 , A61K8/671 , A61K31/19 , A61K31/223 , A61K33/06 , A61K36/00 , A61K36/185 , A61K36/21 , A61K36/28 , A61K36/36 , A61K36/42 , A61K36/49 , A61K36/88 , A61K36/889 , A61K38/34 , A61K2800/70 , A61K2800/75 , A61Q1/02 , A61Q1/12 , A61Q5/006 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/06 , A61Q19/08 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5088 , G01N2500/10 , A61K2300/00
摘要： PROBLEM TO BE SOLVED: To provide an active component capable of stimulating the direct or indirect expression of type 2 and/or type 3 human β-defensin without inducing inflammation, irritation or hypersensitive reaction. SOLUTION: The increase of the amount of β-defensin in human skin prevents the pathogenic specific species (Staphylococcus aureus) from invading excessively into an ecosystem of a body, and contributes for protecting the skin and keeping it to be healthy. The active component is selected from the roots of mugwort, horseweed, bark of a red-berried elder, etc., or their extract, α-MSH, one of its constituting peptides and substance resembling to the peptides. The active components can be used as a cosmetic composition containing the same by 0.01-10 wt. %. Also, the active components can be used as medicinally permissible excipients. As the method for screening the active components without causing inflammation, a skin bio-test method using epithelial cells such as keratinocytes, cornecytes, etc., is cited. COPYRIGHT: (C)2004,JPO

16. 发明专利

JP6145552B1 脂肪肝治療用組成物有权
公开(公告)号：JP6145552B1
公开(公告)日：2017-06-14
申请号：JP2016224986
申请日：2016-11-18
申请人：那須正則
发明人：劉大器 , 那須正則
IPC分类号： A61K36/284 , A61K36/734 , A61K36/537 , A61K36/076 , A61K36/708 , A61K36/752 , A61K36/481 , A61K36/488 , A61K36/704 , A61K36/36 , A61K36/234 , A61K36/185 , A61K36/815 , A61K36/64 , A61K36/8945 , A61K36/40 , A61K36/482 , A61K36/233 , A61P43/00 , A61P1/16 , A61P9/00 , A61P3/10 , A61K36/258
CPC分类号： A61K36/076 , A61K36/185 , A61K36/233 , A61K36/234 , A61K36/258 , A61K36/284 , A61K36/36 , A61K36/40 , A61K36/481 , A61K36/482 , A61K36/488 , A61K36/537 , A61K36/64 , A61K36/704 , A61K36/708 , A61K36/734 , A61K36/752 , A61K36/815 , A61K36/8945 , A61P1/16 , A61P3/10 , A61P9/00 , A61P43/00
摘要：【課題】脂肪肝、特に従来の食事療法、運動療法及び/又は西洋医学的治療によっては改善が見られない脂肪肝であっても有意に改善できる脂肪肝治療用組成物(漢方処方)を提供する。【解決手段】人参(にんじん)、白朮(びゃくじゅつ)、山▲ざ▼(さんざ)、沢瀉(たくしゃ)及び決明子(けつめいし)のエキスを含む脂肪肝治療用組成物。【選択図】なし

17. 发明专利

JP2016147914A 上気道の疾患およびインフルエンザ症候群を治療するための組成物审中-公开
标题翻译：治疗上呼吸道感染和流感综合征病症的组合物
公开(公告)号：JP2016147914A
公开(公告)日：2016-08-18
申请号：JP2016103317
申请日：2016-05-24
申请人：インデナエッセピア
发明人：ボンバルデッリ、エッツィオ
IPC分类号： A61K36/185 , A61K31/4355 , A61K36/66 , A61K31/366 , A61P31/04 , A61P31/12 , A61P31/16 , A61P11/04 , A61P29/00 , A61K9/20 , A61K9/68 , A61K9/08 , A61K9/06 , A61K36/28
CPC分类号： A61K36/36 , A61K31/473 , A61K36/185 , A61K36/28
摘要：【課題】抗菌作用と共にインフルエンザウイルスの大部分の一般的菌株に対する強力な抗ウイルス活性を発揮し、それがインフルエンザによりしばしば生じる上気道の感染および細菌プラークの形成を防止する目的に有用な組成物の提供。【解決手段】本発明は、ベンゾフェナントリジンアルカロイド、Hippophae rhamnoidesの抽出物およびEchinacea angustifoliaの抽出物に基づく組成物であって、抗菌性、抗ウイルス性および抗炎症性活性を有すると共に上気道の細菌およびウイルス感染の治療およびインフルエンザの治療において有用である組成物に関する。【選択図】なし
摘要翻译：要解决的问题：提供对最常见的流感病毒株具有抗菌活性和有效的抗病毒活性的组合物，其可用于预防上呼吸道感染和通常由流感引起的细菌斑块的形成。解决方案：本发明涉及具有抗菌，抗病毒和抗炎活性的苯并菲啶生物碱组合物，沙棘提取物和紫锥菊提取物，可用于治疗上呼吸道细菌和病毒感染，并在治疗流感。选择图：无

18. 发明专利

JP2008019264A Active ingredient stimulating type 2 or type 3 human beta-defensin and cosmetic and pharmaceutical compositions containing such active ingredient 有权
标题翻译：活性成分刺激型2型或3型人类抗坏血酸和包含这种活性成分的化妆品和药物组合物
公开(公告)号：JP2008019264A
公开(公告)日：2008-01-31
申请号：JP2007208376
申请日：2007-08-09
申请人： Engelhard Lyon , Ysl Beaute , エンゲルハード・リヨン , ワイエスエル・ボーテYsl Beaute
发明人： PERRIER ERIC , GUEZENNEC ANNE , PERNET INGRID , REYMERNIER CORINNE , GUESNET JOELLE
IPC分类号： A61K8/30 , A61K31/19 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/365 , A61K8/44 , A61K8/64 , A61K8/67 , A61K8/96 , A61K8/97 , A61K31/07 , A61K31/198 , A61K31/223 , A61K33/06 , A61K36/00 , A61K36/18 , A61K36/28 , A61K36/42 , A61K36/53 , A61K38/00 , A61K38/02 , A61K38/16 , A61K38/34 , A61K39/00 , A61K45/00 , A61P17/00 , A61P17/04 , A61P31/04 , A61P31/10 , A61P43/00 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/06 , A61Q19/08 , C12N5/08 , C12N15/09 , C12Q1/02 , C12Q1/25 , C12Q1/68 , G01N33/50
CPC分类号： A61K8/97 , A61K8/36 , A61K8/365 , A61K8/44 , A61K8/64 , A61K8/671 , A61K31/19 , A61K31/223 , A61K33/06 , A61K36/00 , A61K36/185 , A61K36/21 , A61K36/28 , A61K36/36 , A61K36/42 , A61K36/49 , A61K36/88 , A61K36/889 , A61K38/34 , A61K2800/70 , A61K2800/75 , A61Q1/02 , A61Q1/12 , A61Q5/006 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/06 , A61Q19/08 , G01N33/5008 , G01N33/5023 , G01N33/5044 , G01N33/5088 , G01N2500/10 , A61K2300/00
摘要： PROBLEM TO BE SOLVED: To provide an active ingredient capable of stimulating direct or indirect expression of type 2 and/or type 3 human beta-defensins.
SOLUTION: The active ingredient capable of stimulating direct or indirect expression of type 2 and/or type 3 human beta-defensins without causing any inflammatory, irritation or hypersensitive reaction is chosen from (i) an extract chosen from the group consisting of a quinoa extract, a boldo extract and a mixture of the quinoa and boldo extracts, (ii) jasmonic acid and (iii) mixtures thereof. A cosmetic or pharmaceutical composition containing the active ingredient at a concentration ranging from 0.001 wt.% to 20 wt.% exerts a bactericidal or antifungal property. A screening method for the selection of such active ingredient is also provided.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供能够刺激直接或间接表达2型和/或3型人β-防御素的活性成分。解决方案：能够刺激直接或间接表达2型和/或3型人β-防御素而不引起任何炎症，刺激或过敏反应的活性成分选自（i）选自以下的提取物：藜提取物，粗提物和藜麦酸和粗提物的混合物，（ii）茉莉酸和（iii）其混合物。含有0.001重量％至20重量％浓度的活性成分的化妆品或药物组合物发挥杀菌或抗真菌性能。还提供了选择这种活性成分的筛选方法。版权所有（C）2008，JPO＆INPIT

19. 发明公开

EP3391893A1 MEDICINE COMPOSITION FOR TREATING LEUKEMIA AND PREPARATION METHOD THEREFOR 有权
公开(公告)号：EP3391893A1
公开(公告)日：2018-10-24
申请号：EP16874302.9
申请日：2016-04-08
申请人： Yi Fan Pharmaceutical Academy (Beijing) Co., Ltd. , Yifan Pharmaceutical Co., Ltd.
发明人： CHENG, Xianfeng , ZHOU, Wenyan , LIANG, Xiaodong , QIAN, Liping , XU, Yungao , CHEN, Jinlin
IPC分类号： A61K36/704 , A61K36/537 , A61K36/36 , A61K36/315 , A61K36/19 , A61K33/36 , A61P35/02 , A61P7/00
CPC分类号： A61K33/36 , A61K9/2095 , A61K9/4833 , A61K36/15 , A61K36/19 , A61K36/315 , A61K36/36 , A61K36/537 , A61K36/704 , A61P35/02
摘要： A pharmaceutical composition for treating leukemia, mainly made of the following raw materials by weight percentage: 2 to 8 percent of realgar, 25 to 42 percent of indigo naturalis, 50 to 60 percent of salvia miltiorrhiza, and 6 to 10 percent of heterophylla. The present disclosure improves the preparation method of salvia miltiorrhiza, reduces the amount of the adding water, the number of decocting times and the decocting time. Tanshinone IIA extraction rate reaches 75%. The pharmaceutical composition of the present disclosure can treat leukemia, the complete remission rate reaches 92.9%, the curative effect is obviously improved, and the toxic side effects are greatly reduced.

20. 发明授权

EP2857030B1 COMPOSITION FOR USE IN PREVENTING AND TREATING ALLERGIC DISEASES 有权
公开(公告)号：EP2857030B1
公开(公告)日：2018-10-10
申请号：EP13796431.8
申请日：2013-05-27
申请人： Jiangzhong Pharmaceutical Co., Ltd.
发明人： ZHONG, Hongguang , YI, Minzhi , LU, Jianzhong
IPC分类号： A61K36/73 , A61K36/481 , A61K36/36 , A61K36/344 , A61K36/258 , A61K36/074 , A61P11/06 , A61P37/08 , A61K36/068
CPC分类号： A61K36/738 , A61K9/0053 , A61K9/0056 , A61K9/0095 , A61K9/08 , A61K9/141 , A61K9/1605 , A61K9/2004 , A61K9/4841 , A61K36/062 , A61K36/068 , A61K36/074 , A61K36/258 , A61K36/344 , A61K36/36 , A61K36/481 , A61K36/73 , A61K2236/39 , A61K2300/00
摘要： The present invention relates to use of a composition in the manufacture of health care products or medicaments for prevention and treatment of allergic diseases. The composition is made from raw materials comprising 5 to 200 parts by weight of Ganoderma, 5 to 150 parts by weight of Radix Panacis Quinquefolii or Radix Et Rhizoma Ginseng, 1 to 90 parts by weight of fermented Cordyceps sinensis powder and/or 1 to 120 parts by weight of Cordyceps, or is a composition made from water and/or alcohol extracts of the above raw materials as active components. The allergic diseases include allergic rhinitis, allergic dermatitis, urticaria, and/or allergic asthma.

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