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12. 发明公开

EP3113605A4 MARKING TISSUE SURFACES FOR TREATMENT OF LESIONS BY ELECTRICAL NANOPULSES 有权转让
标题翻译： MARKIERUNG VONGEWEBEOBELFLÄCHENZUR BEHANDLUNG VONLÄSIONENDURCH ELEKTRISCHE NANOIMPULSE
公开(公告)号：EP3113605A4
公开(公告)日：2017-04-19
申请号：EP15758252
申请日：2015-02-23
申请人： PULSE BIOSCIENCES INC
发明人： BLANCO CESAR ESCOBAR , FORSTER ELENA TOVKAN , TAKAHASHI STEFANI REIKO
IPC分类号： A01K11/00 , A61B5/00 , A61N1/04 , A61N1/05
CPC分类号： A61B90/39 , A61B5/444 , A61B18/1206 , A61B18/1402 , A61B2017/00747 , A61B2017/00774 , A61B2018/00452 , A61B2018/143 , A61B2090/3904 , A61B2090/3937 , A61N1/0468 , A61N1/0502 , A61N1/328
摘要： This disclosure relates to an in vivo treatment of a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied. The pulse duration may be at least 1 nanosecond at the full-width-half-maximum. Surface of a tissue surrounding the skin lesion may be marked to guide the device to deliver the electric pulses at substantially precise locations on the lesion surface. This treatment may prevent at least growth of the lesion.
摘要翻译：本公开涉及哺乳动物的皮肤损伤的体内治疗，包括以电脉冲的形式向皮肤损伤施加电能。至少应用一个电脉冲。脉冲持续时间在全宽半最大值处可以是至少1纳秒。可以标记围绕皮肤损伤的组织的表面以引导装置在损伤表面上的基本上精确的位置处递送电脉冲。这种治疗可以至少防止病变的增长。

13. 发明公开

EP1065980A1 APPARATUS FOR DISPENSING AN AMOUNT OF FLUID COOLANT AND A DISPENSING UNIT 有权
标题翻译：装置，使冷却液数量和分布UNIT
公开(公告)号：EP1065980A1
公开(公告)日：2001-01-10
申请号：EP99912175.9
申请日：1999-03-30
申请人： Wartner B.V.
发明人： RUIZENDAAL, Johanna, Cecilia
IPC分类号： A61B17/36 , A61M35/00
CPC分类号： A61M35/003 , A61B18/0218 , A61B2017/00774 , B65D83/285
摘要： The invention relates to a device for administering a quantity of liquid cooling agent, comprising: a container for holding the liquid cooling agent; a normally closed valve connected to the container; operating means for temporarily opening the valve, comprising positioning means for positioning at least a part of the administering element so that the cooling agent leaving the valve can reach the administering element. By means of this measure the greater part of the cooling agent leaving the valve reaches that part of the administering element which comes into contact with the wart, so that it is used effectively. According to a first preferred embodiment the positioning means comprise a chamber which is connected to the valve and into which the cooling agent is carried when the valve is operated, which chamber is adapted for placing of at least a part of the administering element.

14. 发明申请

WO2010088204A1 METHOD FOR TREATING SKIN LESIONS 审中-公开
标题翻译：治疗皮肤损伤的方法
公开(公告)号：WO2010088204A1
公开(公告)日：2010-08-05
申请号：PCT/US2010/022073
申请日：2010-01-26
申请人： FOCUS SURGERY, INC. , SANGHVI, Narendra, T.
发明人： SANGHVI, Narendra, T.
IPC分类号： A61B18/04
CPC分类号： A61N7/02 , A61B2017/00774 , A61N2007/0034
摘要： A method for treatment of skin lesions is provided using High Intensity Focused Ultrasound (HIFU). The method involves administering HIFU to a targeted skin lesion, wherein the application of the HIFU results in the removal of the targeted skin lesion and also results in the removal of skin lesions that are not directly targeted by the application of HIFU.
摘要翻译：使用高强度聚焦超声（HIFU）提供治疗皮肤损伤的方法。该方法涉及将HIFU施用于靶向的皮肤损伤，其中HIFU的施用导致去除靶向的皮肤损伤，并且还导致除去HIFU的非直接靶向的皮肤损伤。

15. 发明申请

WO00036351A1 METHOD AND SYSTEM FOR THE PRODUCTION OF CRYOGENIC MIXTURES AND THE APPLICATION OF SUCH MIXTURES 审中-公开
标题翻译：用于生产低温混合物的方法和系统以及这种混合物的应用
公开(公告)号：WO00036351A1
公开(公告)日：2000-06-22
申请号：PCT/NO1999/000371
申请日：1999-12-08
IPC分类号： A23G9/08 , A23L3/36 , A23L3/375 , A61B17/00 , A61B18/02 , A61K33/00 , C01B32/55 , C09K5/06 , F25J1/00 , F25J1/02 , F25D3/10 , C01B31/22
CPC分类号： F25J1/0276 , A23G9/08 , A23L3/36 , A23L3/375 , A61B18/02 , A61B2017/00774 , A61K33/00 , C01B32/55 , C09K5/066 , F25J1/0012 , F25J1/0015 , F25J1/0037 , F25J1/004 , F25J1/005 , F25J1/0052 , F25J1/0072 , F25J1/0202 , F25J1/0208 , F25J1/0288 , F25J1/0294 , F25J2205/20 , F25J2205/60 , F25J2205/90 , F25J2210/80 , F25J2220/40 , F25J2220/44
摘要： The present application concerns cryogenic mixtures, systems and methods for the production of such mixtures and applications of such mixtures.
摘要翻译：本申请涉及用于生产这种混合物的低温混合物，系统和方法以及这种混合物的应用。

16. 发明申请

WO2008087005A2 DEVICE FOR DISPENSING A COOLANT 审中-公开
标题翻译：分配制冷剂的装置
公开(公告)号：WO2008087005A2
公开(公告)日：2008-07-24
申请号：PCT/EP2008000252
申请日：2008-01-15
申请人： BRAUN MELSUNGEN AG , WIEGAND KARL-HEINZ , SCHMIDT ANDREAS , HAINDL HANS
发明人： WIEGAND KARL-HEINZ , SCHMIDT ANDREAS , HAINDL HANS
IPC分类号： A61B18/02 , A61M35/00 , B05C17/005 , B65D83/14
CPC分类号： A61B18/0218 , A61B2017/00774 , B65D83/303 , B65D83/48
摘要： The invention relates to a device for dispensing a coolant (1), especially a liquid coolant (1), comprising a container (2), configured as a reservoir for the coolant (1), a valve (3) which is arranged on the container (2) and can be opened to dispense the coolant (1) from the container (2) in a dosed manner, an actuator (4) for temporarily opening the valve (3) and an applicator (5) which is detachably arranged on the device and which consists of a support element (6) and an absorption element (7) arranged thereon, wherein at least the absorption element (7) of the applicator (5) can be accommodated in a receptacle (12) of an applicator support (8) of the device. A hollow channel (9) is arranged between the valve (3) and the applicator support (8), through which channel the coolant (1) can be transferred to the applicator support (8) when the valve (3) is opened. The applicator support (8), in terms of its longitudinal extension, is arranged substantially parallel to the longitudinal extension of the container (2) and the applicator (2) can be immobilized in the receptacle (12).
摘要翻译：是用于输送制冷剂（1），特别是液体制冷剂（1），包括一个容器形成装置（2），其作为用于制冷剂（1）的储器，一个布置在容器（2），阀（3），其上用于从所述容器（2）的制冷剂（1）的计量分配可以被打开，操作装置（4），用于暂时打开阀（3），并且可以被布置在该装置敷贴器（5）一个可释放地由支撑元件（6）的和布置在其上的吸收性元件（7），其中至少涂抹器（5）的吸收性元件（7）可以容纳在该装置的涂抹器保持器（8）的容器（12）中。在这种情况下，存在设置在阀（3）和涂敷器支撑件（8），通过该，在打开阀（3），制冷剂（1）可以被转移到施用载体（8）之间的中空通道（9），其中，所述涂覆器支架（8）在它们的纵向延伸部分大致平行于容器（2）的纵向延伸部分布置，并且容器（12）中的施用器（2）是可固定的。

17. 发明申请

WO2007082072A3 TREATMENT OF WARTS AND OTHER DERMATOLOGICAL CONDITIONS USING TOPICAL ULTRASONIC APPLICATOR 审中-公开
标题翻译：使用局部超声波应用者治疗战争和其他皮肤病
公开(公告)号：WO2007082072A3
公开(公告)日：2007-10-18
申请号：PCT/US2007000876
申请日：2007-01-11
申请人： SURESHOT MEDICAL DEVICE INC , THIERMAN JONATHAN S
发明人： THIERMAN JONATHAN S
IPC分类号： A61N7/02 , A61M37/00
CPC分类号： A61N7/02 , A61B2017/00084 , A61B2017/00128 , A61B2017/00734 , A61B2017/00774 , A61M37/0092
摘要： A method and system including an applicator for treating dermatological conditions such as warts is presented for applying ultrasonic energy from a specially-designed ultrasonic energy applicator designed for use with localized dermatological conditions to heat an affected localized region sufficiently to achieve a desired therapeutic result. Specific embodiments include temperature measurement and/or sensing and/ or actuation by way of a temperature sensor coupled to the ultrasonic energy applicator. Also, a medicated ultrasound-compatible patch is disclosed for applying to a region of tissue to be treated and includes substances known to aid in the treatment of a condition and adapted for transmitting the ultrasound energy into the region of tissue.
摘要翻译：提出了一种包括用于治疗皮肤病学条件如疣的施用器的方法和系统，用于从专门设计用于局部皮肤病学条件的专门设计的超声能量施加器施加超声波能量，以充分加热受影响的局部区域以获得期望的治疗结果。具体实施例包括通过耦合到超声波能量施加器的温度传感器的温度测量和/或感测和/或致动。此外，公开了一种用于施用于待治疗组织的区域的药物超声相容性贴片，并且包括已知有助于治疗病症并适于将超声能量传输到组织区域中的物质。

18. 发明申请

WO2005007202A3 SURGICAL CUTTING TOOLS AND RELATED METHODS 审中-公开
标题翻译：手术切割工具及相关方法
公开(公告)号：WO2005007202A3
公开(公告)日：2005-06-09
申请号：PCT/US2004022051
申请日：2004-07-08
申请人： UNIV TEXAS , MANSFIELD PAUL
发明人： MANSFIELD PAUL
IPC分类号： A61B17/22 , A61B17/32 , A61L20060101
CPC分类号： A61B17/32093 , A61B17/3205 , A61B17/3213 , A61B2017/00761 , A61B2017/00774
摘要： Surgical cutting tools, methods of using them, and kits containing them. One of the surgical cutting tools (10) includes a cutting portion (15) and a handle portion (20) that meet at an angle greater than 20 degrees, and the cutting portion includes a sharp bent edge.
摘要翻译：手术切割工具，使用方法和包含它们的工具包。手术切割工具（10）之一包括切割部分（15）和以大于20度的角度相交的手柄部分（20），并且切割部分包括尖锐的弯曲边缘。

19. 发明公开

EP2531124A4 METHOD AND DEVICES FOR THE TREATMENT OF SKIN LESIONS 有权转让
公开(公告)号：EP2531124A4
公开(公告)日：2017-12-20
申请号：EP11739478
申请日：2011-02-03
申请人： TUVIDERM LLC
发明人： LIND ZECHARIA
IPC分类号： A61B18/02 , A61B17/00 , A61B17/30
CPC分类号： A61B18/02 , A61B18/0218 , A61B2017/00774 , A61B2017/305 , A61B2018/0225
摘要： A tweezers device for the application of cryogenic matter directly on a skin lesion while protecting the collateral skin tissue from being damaged by the cryogenic matter, the device comprising an applicator body configured with opposing tweezer arms, each tweezer arm including a cryogenic matter application element such that when the opposing tweezer arms are closed about the skin lesion, the skin lesion is substantially encased by the cryogenic matter application elements.

20. 发明授权

EP1720586B1 APPARATUS FOR DEBRIDEMENT OF SKIN LESIONS 失效转让
标题翻译：装置脱除皮肤伤害
公开(公告)号：EP1720586B1
公开(公告)日：2012-08-29
申请号：EP05703144.5
申请日：2005-01-27
申请人： Ramot at Tel-Aviv University Ltd. , Enzysurge Ltd.
发明人： FREEMAN, Amihay , HIRSZOWICZ, Eran , BE'ERI-LIPPERMAN, Michal
IPC分类号： A61M1/00 , A61K38/48
CPC分类号： A61M3/0258 , A61B10/0035 , A61B10/02 , A61B17/545 , A61B2017/00761 , A61B2017/00769 , A61B2017/00774 , A61B2017/22082 , A61B2017/3411 , A61K38/48 , A61K38/4886 , A61M1/0088 , A61M3/0241 , A61M3/0283 , A61M3/0287 , A61M27/00 , C12M45/09 , C12N5/0629 , C12N2509/00

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