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11. 发明公开

KR1020030087448A 스핑고신-1-포스페이트 및 그 유도체를 포함하는 미백화장료 조성물 有权
标题翻译：含皮肤素-1-磷酸酯及其衍生物的皮肤白化化妆品组合物
公开(公告)号：KR1020030087448A
公开(公告)日：2003-11-14
申请号：KR1020020025814
申请日：2002-05-10
申请人： 주식회사 웰스킨
发明人： 박경찬 , 김동석 , 김숙영 , 이재은
IPC分类号： A61K8/55 , A61K8/68 , A61Q19/02
摘要： PURPOSE: Provided is a skin whitening cosmetic composition containing sphingosine-1-phosphate and its derivatives which inhibit the generation of melanin on melanin cells, and promote ERK activity and MIFT decomposition to inhibit the activity of tyrosinase and consequently the generation of melanin. CONSTITUTION: A skin whitening cosmetic composition is characterized by containing sphingosine-1-phosphate represented by the formula(1) in the amount of 0.01-30.0 wt.% and its derivatives, wherein the composition is formulated into one kind selected from the group consisting of emulsion, toilet water, cream, facial pack, beauty wash, and ointment.
摘要翻译：目的：提供含有鞘氨醇-1-磷酸及其衍生物的皮肤美白化妆品组合物，其抑制黑色素细胞上的黑色素的产生，并促进ERK活性和MIFT分解以抑制酪氨酸酶的活性并因此产生黑色素。构成：皮肤美白化妆品组合物的特征在于，含有0.01-30.0重量％的由式（1）表示的鞘氨醇-1-磷酸酯及其衍生物，其中组合物配制成以下组中的一种：的乳液，马桶水，奶油，面包，美容洗剂和软膏。

12. 发明公开

KR1020030073441A 탄닌을 포함하는 항균 조성물 无效
标题翻译：含有鞣剂的抗菌组合物
公开(公告)号：KR1020030073441A
公开(公告)日：2003-09-19
申请号：KR1020020012998
申请日：2002-03-11
申请人： 주식회사 웰스킨
发明人： 박경찬 , 최영 , 박서형
IPC分类号： A61K31/35
摘要： PURPOSE: An antibacterial composition including a plant extract containing tannin as an effective ingredient is provided. The tannin has an excellent antibacterial effect against Propionibacterium acne, Staphylococcus epidermidis and Staphylococcus aureus and is harmless to a human body. Thus, the plant extract containing tannin is used in prevention and treatment of disease caused by cutaneous bacteria. CONSTITUTION: An antibacterial composition contains 0.001 to 20% by weight of tannin contained in an extract of one or more plants selected from Arctostaphylos uva-ursi, Paeoniae Radix rubra, Paeoniae Radix, Lonicerae Flos, Galla Rhois, Quercus infectoria Oliver, Vitis vinifera L., Theae folium, Quercus dentata Thunb. and Mimosa pudica. The antibacterial composition is applied to the affected areas of the skin in a concentration of 0.001 to 1,000mg/ml 1 to 3 times a day.
摘要翻译：目的：提供包含含有单宁作为有效成分的植物提取物的抗菌组合物。单宁对痤疮丙酸杆菌，表皮葡萄球菌和金黄色葡萄球菌具有优异的抗菌作用，对人体无害。因此，含有单宁的植物提取物用于预防和治疗由皮肤细菌引起的疾病。构成：抗菌组合物含有选自Arctostaphylos uva-ursi，Paeoniae Radix rubra，Paeoniae Radix，Lonicerae Flos，Galla Rhois，Quercus infectoria Oliver，Vitis vinifera L的一种或多种植物提取物中含有的单宁重量为约0.001-20％ ae叶，栎属栎属Thunb。和含羞草。将抗菌组合物以0.001至1,000mg / ml的浓度每天1至3次施用于皮肤的受影响区域。

13. 发明公开

KR1020030012562A 홍경천 추출물을 포함하는 미백 조성물 有权
标题翻译：含有RHODIOLA ROSEA萃取物的白色组合物
公开(公告)号：KR1020030012562A
公开(公告)日：2003-02-12
申请号：KR1020010046636
申请日：2001-08-01
申请人： 주식회사 웰스킨
发明人： 박경찬 , 최영 , 김순겸
IPC分类号： A61K8/97 , A61Q19/02
CPC分类号： A61K8/97 , A61Q19/00 , A61Q19/02
摘要： PURPOSE: A whitening composition containing a Rhodiola rosea extract which has excellent whitening action and safety to a human body as a main component is provided which has a toxicity inhibiting action on hydrogen peroxide-inducing cells, an effect of inhibiting human tyrosinase activity and a melamine production-inhibiting action. CONSTITUTION: The whitening composition contains 0.001 to 10% by weight of a Rhodiola rosea extract, based on the total weight of the composition. The Rhodiola rosea extract is extracted from one or more solvents selected from the group consisting of ethanol, petroleum ether, chloroform, ethyl acetate and butanol. The composition is formulated into an emollient lotion, skin lotion, nourishing cream, massage cream, essence, pack, adhesive skin patch or gel.
摘要翻译：目的：提供一种美白组合物，其含有对人体作为主要成分具有优异的美白作用和安全性的红景天提取物，其对过氧化氢诱导细胞具有毒性抑制作用，抑制人酪氨酸酶活性的作用和三聚氰胺生产抑制作用。构成：基于组合物的总重量，美白组合物含有约10％至10％的红景天提取物。从一种或多种选自乙醇，石油醚，氯仿，乙酸乙酯和丁醇的溶剂中提取红景天提取物。该组合物被配制成润肤乳液，皮肤洗剂，滋养霜，按摩膏，精华，包装，粘性皮肤贴剂或凝胶。

14. 发明公开

KR1020020073776A 루시놀을 함유하는 화장료 조성물 有权
标题翻译：含有RESORCINOL的化妆品组合物
公开(公告)号：KR1020020073776A
公开(公告)日：2002-09-28
申请号：KR1020010013592
申请日：2001-03-16
申请人： 주식회사 웰스킨
发明人： 박경찬 , 정진호 , 최영 , 김숙영
IPC分类号： A61K8/34 , A61K8/68 , A61Q19/02
CPC分类号： A61K8/347 , A61K8/68 , A61Q19/00 , A61Q19/08
摘要： PURPOSE: A cosmetic composition containing resorcinol, sphingolipid and metabolite thereof is provided which has a skin whitening action and antioxidation action to inhibit oxidative damage of a biomaterial, thereby deferring and preventing skin aging. CONSTITUTION: The cosmetic composition contains 0.001 to 5% 4-n-butyl-resorcinol by weight represented by the formula 1 and 0.01 to 20% sphingolipid and metabolite thereof by weight, based on the total weight of the composition and is selected from the group consisting of a skin lotion, astringent lotion, nourishing lotion, nourishing cream, massage cream, essence, pack, powder, ointment, suspension, emulsion, spray and cosmetic liquid.
摘要翻译：目的：提供含有间苯二酚，鞘脂及其代谢物的化妆品组合物，其具有抑制生物材料的氧化损伤的皮肤美白作用和抗氧化作用，从而延缓和防止皮肤老化。构成：化妆品组合物含有0.001至5重量％的由式1表示的4-正丁基间苯二酚和0.01至20重量％的鞘脂及其代谢物，基于组合物的总重量，并且选自组包括皮肤洗剂，涩味乳液，滋养乳液，滋养霜，按摩霜，精华，包装，粉末，软膏，悬浮液，乳液，喷雾和化妆品液体。

15. 发明公开

KR1020020027919A 스핑고리피드 또는 그 대사산물을 함유하는 미백 화장료조성물 有权
标题翻译：含有弹性体或其代谢物的白色化妆品组合物
公开(公告)号：KR1020020027919A
公开(公告)日：2002-04-15
申请号：KR1020000058715
申请日：2000-10-06
申请人： 주식회사 웰스킨
发明人： 박경찬
IPC分类号： A61K8/68 , A61Q19/02
CPC分类号： A61K8/68 , A61Q19/00 , A61Q19/02
摘要： PURPOSE: A whitening cosmetic composition containing sphingolipid or its metabolite is provided, therefore Akt/PKB can be deactivated to inhibit the growth of melanin cells, and the activity of tyrosinase can be inhibited, to decrease the formation of melanin. CONSTITUTION: The whitening cosmetic composition having inhibiting effect on the growth of melanin cells and formation of melanin contains sphingolipid or its metabolite as active ingredient, in which the sphingolipid or its metabolite, particularly active-ceramide is added into the whitening cosmetic composition in an amount of 0.01 to 30.0 wt.%. The whitening cosmetic composition can be formulated into lotion, emulsion, cream, mask pack or the like.
摘要翻译：目的：提供含有鞘脂或其代谢物的美白化妆品，因此可以使Akt / PKB失活以抑制黑色素细胞的生长，并可抑制酪氨酸酶的活性，以减少黑色素的形成。构成：对黑色素细胞的生长和黑色素的生长具有抑制作用的美白化妆品组合物含有鞘脂或其代谢物作为活性成分，其中将鞘脂或其代谢物，特别是活性神经酰胺以一定量加入到美白化妆品组合物中为0.01〜30.0重量％。美白化妆品组合物可配制成乳液，乳液，霜剂，口罩包装等。

16. 发明公开

KR1020110083088A 다이펩타이드를 유효성분으로 포함하는 섬유모세포 증식 조성물 및 상기 조성물을 포함하는 제품 无效
标题翻译：含有除去剂和含有组合物的产品的纤维素刺激组合物
公开(公告)号：KR1020110083088A
公开(公告)日：2011-07-20
申请号：KR1020100003120
申请日：2010-01-13
申请人： 주식회사 웰스킨
发明人： 강윤아 , 이현경 , 최혜령
IPC分类号： A61K38/05 , A61P17/00 , C07K5/06
CPC分类号： A61K38/05 , A23L33/18 , A61K8/64 , A61Q19/08 , C07K5/06
摘要： PURPOSE: A fibroblast proliferation composition containing dipeptides is provided to enable wound healing and to proliferate fibroblasts on aged skin. CONSTITUTION: A fibroblast proliferation composition contains 0.001-30 weight% of dipeptides. The composition further contains pharmaceutically acceptable carrier or excipient. The composition is manufactured in the form of skin, lotion, cream, foundation, gel, pack, foam, body oil, lip stick, or makeup base. A food additive contains the composition.
摘要翻译：目的：提供含有二肽的成纤维细胞增殖组合物，以使伤口愈合并在老化皮肤上增殖成纤维细胞。构成：成纤维细胞增殖组合物含有0.001-30重量％的二肽。组合物还含有药学上可接受的载体或赋形剂。该组合物以皮肤，洗剂，奶油，粉底，凝胶，包装，泡沫，人体油，唇膏或化妆基底的形式制造。食品添加剂含有该组合物。

17. 发明公开

KR1020090055891A 피부용 엘이디 광 조사기 无效
标题翻译： LED散热器用于皮肤
公开(公告)号：KR1020090055891A
公开(公告)日：2009-06-03
申请号：KR1020070122758
申请日：2007-11-29
申请人： 주식회사 웰스킨 , 천영문
发明人： 천영문 , 권선방
IPC分类号： A61N5/06
摘要： An LED light illuminating apparatus for the skin is provided, which can be widely applied to the various forms of bodies and obtains durability. An LED light illuminating apparatus for the skin comprises: an optical irradiation head(30) having more than one LED array comprising a plurality of same wavelength LEDs and connection neck; a middle lobe panel(31) of the optical irradiation head; a left lobe panel(33); and a right lobe panel. A stand consists of a leg and a plurality of multi-joint stems. A controller is mounted on the stand stem.
摘要翻译：提供了一种用于皮肤的LED灯照明装置，其可以广泛地应用于各种形式的身体并获得耐久性。一种用于皮肤的LED灯照明装置包括：具有多于一个LED阵列的光照射头（30），其包括多个相同的波长LED和连接颈部; 光学照射头的中间叶片面板（31）; 左叶片面板（33）; 和右叶片面板。支架由腿部和多个多关节杆组成。控制器安装在支架杆上。

18. 发明公开

KR1020090001013A 인돌-3-알킬카복실산을 함유하는 여드름 치료제 및 피지분비 억제제, 및 이를 포함하는 광역학적 치료용 키트 无效
标题翻译： ACNE治疗剂和包含吲哚-3-甲酰胆碱的SEBUM SECERNENT INHIBITOR和用于含有它的光动力疗法的胶囊
公开(公告)号：KR1020090001013A
公开(公告)日：2009-01-08
申请号：KR1020070065046
申请日：2007-06-29
申请人： 주식회사 웰스킨
发明人： 김동석 , 김소영 , 권선방
IPC分类号： A61K31/405 , A61P17/10
CPC分类号： A61K41/0057 , A61K31/405 , A61K41/0038
摘要： A photosensitive agent for treating the pimple, a photosensitive agent for inhibiting the secretion of sebum, and a composition or a kit using the agent are provided to improve the pimple treating effect and the anti-sebum effect. A photosensitive agent for treating the pimple comprises an indole-3-alkylcarboxylic acid represented by the formula 1, or its pharmaceutically acceptable salt, wherein n is an integer of 0-3. Preferably the agent shows a photosensitivity to the light of 280-1,000 nm.
摘要翻译：提供用于治疗痘痘的感光剂，用于抑制皮脂分泌的感光剂，以及使用该试剂的组合物或试剂盒，以改善疙瘩治疗效果和抗皮脂效果。用于处理疙瘩的光敏剂包含由式1表示的吲哚-3-烷基羧酸或其药学上可接受的盐，其中n为0-3的整数。优选地，该试剂对280-1,000nm的光显示出光敏性。

19. 发明授权

KR100700324B1 자극시스템을 이용한 다공성 및 인장 강도가 높은 콜라겐지지체 배양방법 有权
标题翻译：通过刺激系统改善包括多孔和拉伸强度的胶原的基质的培养方法
公开(公告)号：KR100700324B1
公开(公告)日：2007-03-29
申请号：KR1020050105929
申请日：2005-11-07
申请人： 주식회사 웰스킨
发明人： 권선방 , 박경찬 , 최혜령
IPC分类号： C12N5/071 , C12N5/00
CPC分类号： C12N5/0698 , C12M25/14 , C12N2502/094 , C12N2502/1323 , C12N2533/54
摘要： A method for culturing a collagen scaffold is provided to increase the production of collagen by applying periodic stimulus in a vertical direction when culturing a collagen gel, thereby increasing the tensile strength of the scaffold and capable of culturing a surgically operable scaffold. The method for culturing collagen scaffold having high porosity and tensile strength comprises the steps of: (a) preparing a collagen gel containing cells in a culture container made of an elastic material; and (b) applying periodic stimulus to the lower portion of the culture container so as to apply the stimulus to the collagen gel through the elastic material. In the step (b), the frequency of the stimulus is 0.01-500 times/minute and the strength of the stimulus is 1.0 x 10^-7 to 1.0 x 10^-1 N/m^2. The collagen scaffold prepared by the method has the porosity of 0.1-100 micrometers and the tensile strength of 5-200N/cm^2.
摘要翻译：提供培养胶原支架的方法，通过在培养胶原凝胶时在垂直方向施加周期性刺激来增加胶原蛋白的产生，从而增加支架的拉伸强度并能够培养外科手术的支架。用于培养具有高孔隙率和拉伸强度的胶原支架的方法包括以下步骤：（a）在由弹性材料制成的培养容器中制备含有细胞的胶原凝胶; 和（b）对培养容器的下部施加周期性刺激，以通过弹性材料将刺激施加到胶原凝胶上。在步骤（b）中，刺激频率为0.01-500次/分钟，刺激强度为1.0×10 ^ -7〜1.0×10 ^ 1N / m ^ 2。通过该方法制备的胶原支架的孔隙率为0.1-100微米，拉伸强度为5-200N / cm ^ 2。

20. 发明授权

KR100589716B1 멜라닌 생성 저해용 조성물 失效
标题翻译：用于抑制梅毒素合成的组合物
公开(公告)号：KR100589716B1
公开(公告)日：2006-06-15
申请号：KR1020040004438
申请日：2004-01-20
申请人： 주식회사 웰스킨
发明人： 박경찬 , 김동석 , 박서형
IPC分类号： A61K8/97 , A61Q19/02
摘要： 본 발명은 멜라닌 생성 저해용 조성물에 관한 것이다. 특히 본 발명은 MITF(microphthalmia-associated transcription factor) 및 티로시나제 발현을 억제하면서 동시에 티로시나제 활성을 억제할 뿐만 아니라, 병용사용시 상승적인 멜라닌 생성 저해효과를 나타내는, 히노키티올, 및 녹차 추출물 또는 EGCG(epigallocatechin gallate)을 유효성분으로 포함하는 멜라닌 생성 저해용 조성물을 제공한다.
히노키티올, 녹차추출물, EGCG, 미백, 티로시나제, 멜라닌, MITF

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