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11. 发明授权

US06385481B1 Diagnostic system with a chair and table movable on rails provided on vertical magnets thereof 有权
公开(公告)号：US06385481B1
公开(公告)日：2002-05-07
申请号：US09218402
申请日：1998-12-22
申请人： Katsumasa Nose , Osamu Furuta , Kazuhiko Hayakawa , Masaaki Sakuma , Yujiro Hayashi
发明人： Katsumasa Nose , Osamu Furuta , Kazuhiko Hayakawa , Masaaki Sakuma , Yujiro Hayashi
IPC分类号： A61B5055
摘要： The present invention is directed to joint motion imaging and provides a vertical magnet type MRI system comprising a vertical magnet unit (10) having a pair of opposite vertical magnets (11), a movable table (20) provided with wheels (22) for traveling and a cradle (21) to carry a specimen laid down thereon, and capable of being moved into and moved out of a space between the pair of opposite vertical magnets (11), table locking devices (13) for locking the movable table (20) with the cradle (21) being in place between the pair of opposite vertical magnets (11), a movable chair (30) provided with wheels (32) for traveling and capable of being moved into and moved out of the space between the pair of opposite vertical magnets (11), and a chair locking device (14) for locking the movable chair (30) in place between the pair of opposite vertical magnets (11).

12. 发明授权

US5832950A Fuel interruption means of fuel tank 失效
标题翻译：燃油箱燃油中断装置
公开(公告)号：US5832950A
公开(公告)日：1998-11-10
申请号：US711044
申请日：1996-09-10
申请人： Shinya Shimada , Hiroshi Takaki , Yujiro Hayashi
发明人： Shinya Shimada , Hiroshi Takaki , Yujiro Hayashi
IPC分类号： B60K15/077 , B60K15/035 , F02M37/00 , F16K24/00 , F16K24/04 , F16K31/18 , F16K31/22
CPC分类号： F16K24/044 , B60K15/03519 , Y10T137/0874 , Y10T137/3099 , Y10T137/86936
摘要： In a fuel interruption device for a fuel tank, a main valve is prevented from opening as a result of the action of an auxiliary valve during closure of the main valve; and more specifically, an auxiliary valve which is caused to move up and down by a float and a main valve which moves up and down in linkage with the up and down movement of the auxiliary valve are accommodated inside a casing which allows the inflow and outflow of liquid fuel and is provided at the end of a passage which connects the fuel tank and canister; a linking projection is provided on one of the valves, that is, either the auxiliary valve or the main valve, so that the main valve moves in linkage with the auxiliary valve in an action that is either advanced or retarded within a predetermined range, and a projection regulating groove into which the linking projection is inserted so that the projection can change its position within the range is formed in the other valve; and auxiliary valve seat and main valve seat open independently in the upper portion of the casing or in the end of the passage.
摘要翻译：在用于燃料箱的燃料中断装置中，由于在主阀关闭期间辅助阀的作用，防止了主阀的打开; 更具体地说，通过浮子上下升降的辅助阀和与辅助阀的上下运动相联动地上下移动的主阀被容纳在允许流入和流出的壳体内并且设置在连接燃料箱和罐的通道的端部; 在一个阀，即辅助阀或主阀上设置有连接凸起，使得主阀与辅助阀联动，在预定范围内提前或延迟的动作，以及突起限制槽，其中插入连接突起使得突起能够在该范围内改变其位置，在另一个阀中形成; 辅助阀座和主阀座在外壳的上部或通道的末端独立地打开。

13. 发明授权

US5118615A Peptide and gene coding for same 失效
标题翻译：肽和基因编码相同
公开(公告)号：US5118615A
公开(公告)日：1992-06-02
申请号：US023818
申请日：1987-03-09
申请人： Hisayuki Matsuo , Kenji Kangawa , Yujiro Hayashi , Shinzo Oikawa , Takehiro Oshima , Shoji Tanaka , Hiroshi Nakazato , Yasunori Tawaragi
发明人： Hisayuki Matsuo , Kenji Kangawa , Yujiro Hayashi , Shinzo Oikawa , Takehiro Oshima , Shoji Tanaka , Hiroshi Nakazato , Yasunori Tawaragi
IPC分类号： A61K38/00 , C07K14/58 , C12N15/12 , C12N15/70
CPC分类号： C07K14/58 , C12N15/70 , A61K38/00 , Y10S514/869
摘要： Disclosed is a DNA fragment comprising a base sequence coding for a peptide occurring in human atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant.Also disclosed is a new peptide consisting of 126 amino acids occurring in human atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.
摘要翻译：公开了一种DNA片段，其包含编码人心房中出现的具有利尿作用或肽前体的肽的碱基序列，含有该DNA片段的质粒，用质粒转化的微生物，以及使用转化子。还公开了由人心房中出现的126个氨基酸及其前体组成的新肽。肽具有显着的利尿作用和降血压或降压作用。

14. 发明申请

US20150238570A1 THERAPEUTIC AGENT FOR HYPERTHERMIA 有权
标题翻译：高血压治疗药物
公开(公告)号：US20150238570A1
公开(公告)日：2015-08-27
申请号：US14002570
申请日：2011-09-02
申请人： Noboru Murakami , Keiko Nakahara , Kenji Kangawa , Yujiro Hayashi
发明人： Noboru Murakami , Keiko Nakahara , Kenji Kangawa , Yujiro Hayashi
IPC分类号： A61K38/22
CPC分类号： A61K38/22
摘要： An object of the present invention is to provide a hypothermic agent for an animal, a therapeutic agent for hyperthermia in an animal, etc. The present invention provides a hypothermic agent for an animal, a therapeutic agent for hyperthermia in an animal, etc., the agents etc. comprising desacyl ghrelin or its derivative, or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要翻译：本发明的目的在于提供动物的低温药，动物体内的热疗用治疗剂等。本发明提供动物用低温药，动物体内的高热治疗剂等，所述药剂等包含脱酰基生长素释放肽或其衍生物或其药学上可接受的盐作为活性成分。

15. 发明申请

US20130217901A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE 4-CHLORO-3-HYDROXYBUTANAL COMPOUND 有权
标题翻译：用于生产光学活性的4-氯代-3-羟基吡啶化合物的方法
公开(公告)号：US20130217901A1
公开(公告)日：2013-08-22
申请号：US13880640
申请日：2011-10-19
申请人： Yujiro Hayashi
发明人： Yujiro Hayashi
IPC分类号： C07C45/00 , C07D301/26 , C07C67/00 , C07C41/01
CPC分类号： C07C45/00 , C07B53/00 , C07B2200/07 , C07C41/01 , C07C41/56 , C07C45/72 , C07C67/00 , C07C67/343 , C07D301/26 , C07D303/12 , C07D303/16 , C07C69/732 , C07C47/195 , C07C43/315 , C07C47/273
摘要： The invention relates to a method of producing optically active 4-chloro-3-hydroxybutanal compound (2) by reacting chloroacetaldehyde with aldehyde compound (1) in the presence of optically active pyrrolidine compound (5). wherein each symbol is as defined in the specification.
摘要翻译：本发明涉及通过在光学活性吡咯烷化合物（5）的存在下使氯乙醛与醛化合物（1）反应制备光学活性的4-氯-3-羟基丁醛化合物（2）的方法。其中每个符号如说明书中所定义。

16. 发明申请

US20130211139A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ALDEHYDE COMPOUND 失效
标题翻译：用于生产光学活性的氨基铝酸盐化合物的方法
公开(公告)号：US20130211139A1
公开(公告)日：2013-08-15
申请号：US13880675
申请日：2011-10-19
申请人： Yujiro Hayashi
发明人： Yujiro Hayashi
IPC分类号： C07C303/40
CPC分类号： C07C303/40 , C07B53/00 , C07B2200/07 , C07C2601/14 , C07C311/16 , C07C311/17
摘要： The invention relates to a method of producing optically active β-aminoaldehyde compound (3) by reacting imine compound (1-1) or sulfone compound (1-2) with aldehyde compound (2) in the presence of an optically active pyrrolidine compound. wherein each symbol is as defined in the specification.
摘要翻译：本发明涉及通过使亚胺化合物（1-1）或砜化合物（1-2）与醛化合物（2）在光学活性吡咯烷化合物存在下反应制备光学活性β-氨基醛化合物（3）的方法。其中每个符号如说明书中所定义。

17. 再颁专利

USRE43038E1 Compound having antitumor activity and process for producing the same 失效
标题翻译：具有抗肿瘤活性的化合物及其制备方法
公开(公告)号：USRE43038E1
公开(公告)日：2011-12-20
申请号：US13092127
申请日：2003-06-06
申请人： Hiroyuki Osada , Hideaki Kakeya , Yujiro Hayashi
发明人： Hiroyuki Osada , Hideaki Kakeya , Yujiro Hayashi
IPC分类号： C07D207/00 , C07D209/32 , C07D303/38 , C07D491/02
CPC分类号： C07D491/04 , A61K31/407
摘要： A compound represented by the general formula (I): (I) wherein R represents linear, branched, or cyclic alkyl or aryl; a process for producing the compound; and an antitumor agent containing the compound as an active ingredient.
摘要翻译：由通式（I）表示的化合物：（I）其中R表示直链，支链或环状的烷基或芳基; 一种制备该化合物的方法; 和含有该化合物作为活性成分的抗肿瘤剂。

18. 发明申请

US20110039783A1 PEPTIDE HAVING HYPOTENSIVE ACTIVITY 审中-公开
标题翻译：具有高血压活性的肽
公开(公告)号：US20110039783A1
公开(公告)日：2011-02-17
申请号：US12666465
申请日：2008-06-27
申请人： Atsushi Okamoto , Koji Magota , Yujiro Hayashi
发明人： Atsushi Okamoto , Koji Magota , Yujiro Hayashi
IPC分类号： A61K38/16 , C07K14/00 , C07K16/44 , C12P21/02 , A61P9/12
CPC分类号： C07K14/47 , A61K38/00 , C07K7/06 , C07K7/08
摘要： The present invention provides a novel peptide having a physiological activity. Because of having a hypotensive activity, this novel peptide is useful in treating a disease caused by hypertension. Also, an antibody to the novel peptide is provided.
摘要翻译：本发明提供具有生理活性的新型肽。由于具有低血压活性，该新型肽可用于治疗由高血压引起的疾病。此外，提供了针对新肽的抗体。

19. 发明授权

US6141580A Detecting coil for magnetic resonance diagnostic apparatus 有权
标题翻译：磁共振诊断仪检测线圈
公开(公告)号：US6141580A
公开(公告)日：2000-10-31
申请号：US209604
申请日：1998-12-11
申请人： Yujiro Hayashi , Masaaki Sakuma
发明人： Yujiro Hayashi , Masaaki Sakuma
IPC分类号： G01R33/3415 , A61B5/055 , G01R33/34
CPC分类号： G01R33/341 , G01R33/34046 , G01R33/34084
摘要： In order not to nip the clothes or skin of a subject between the joining portions of coil members when a detecting coil for a magnetic resonance diagnostic apparatus is fitted around a region of the subject such as the leg or neck, the detecting coil 100 for a magnetic resonance diagnostic apparatus, which can be separated into an upper coil member 10 and a lower coil member 20 and has an annular shape when these members 10, 20 are integrally joined, is provided at the joining portions of the lower coil member 20 with guards 27, 28 of a silicone rubber having a hardness of Hs80.
摘要翻译：为了在用于磁共振诊断装置的检测线圈安装在诸如腿部或颈部的对象的区域周围时，为了不在被卷绕在线圈部件的接合部分之间的受试者的衣服或皮肤夹持，磁共振诊断装置，在上部线圈部件10和下部线圈部件20分离的同时，在下部线圈部件20的连接部分设有保护件 27，28，硬度为Hs80的硅橡胶。

20. 发明授权

US09078868B2 Therapeutic agent for accelerating recovery of animal under medical treatment 有权
标题翻译：用于加速医疗恢复的治疗剂
公开(公告)号：US09078868B2
公开(公告)日：2015-07-14
申请号：US13522203
申请日：2011-01-14
申请人： Noboru Murakami , Keiko Nakahara , Kenji Kangawa , Yujiro Hayashi
发明人： Noboru Murakami , Keiko Nakahara , Kenji Kangawa , Yujiro Hayashi
IPC分类号： A61K38/25 , A61K38/00 , A61K38/22
CPC分类号： A61K38/25 , A61K38/00 , A61K38/2264
摘要： An object of the present invention is to provide a therapeutic agent for accelerating recovery to accelerate a return to normal physical conditions by administering to an animal not in good health and under medical treatment, a treatment method, and the like. There is provided a therapeutic agent for accelerating recovery for animal use to accelerate the improvement of a physical condition of an animal under medical treatment which has a decreased activity (vigor) and is exhausted, which contains ghrelin or a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient and improves one or more of evaluation parameters consisting of activity (vigor), blood cell test values, biochemical test values, body temperature, the degree of anger or anxiety, and respiratory rate.
摘要翻译：本发明的目的是提供一种治疗剂，其用于加速恢复，通过给予不良健康和医疗处理的动物，治疗方法等来加速恢复正常的身体状况。提供了用于加速动物使用恢复的治疗剂，以加速具有降低的活性（活力）并且被排出的动物的身体状况的改善，其含有生长素释放肽或其衍生物或药学上可接受的盐作为活性成分，改善由活性（活力），血细胞试验值，生化试验值，体温，愤怒或焦虑程度和呼吸频率组成的评价参数中的一种或多种。

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