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11. 发明授权

US07928631B2 Stable electro-mechanical comb drive actuators 有权
标题翻译：稳定的机电梳驱动执行机构
公开(公告)号：US07928631B2
公开(公告)日：2011-04-19
申请号：US11394950
申请日：2006-03-31
申请人： Vladimir Anatolyevich Aksyuk , Carl Jeremy Nuzman , Maria Elina Simon , Alan Weiss
发明人： Vladimir Anatolyevich Aksyuk , Carl Jeremy Nuzman , Maria Elina Simon , Alan Weiss
IPC分类号： H02N2/00 , G02B26/08
CPC分类号： H02N1/008 , G02B7/1827 , G02B26/0841
摘要： An electro-mechanical actuator includes a comb drive and a deformable connector. The comb drive has a first capacitor plate and a second capacitor plate. The capacitor plates have teeth capable of inter-digitating. The deformable connector is configured to apply a mechanical restoring force to the first capacitor plate. The deformable connector is configured to restore the first capacitor plate to be at an equilibrium rest position in response to no control voltage being applied across the capacitor. The comb drive is more engaged at the equilibrium rest position than at a mechanical stability threshold of the comb drive. The capacitor plates are disengaged at the equilibrium rest position.
摘要翻译：机电致动器包括梳状驱动器和可变形连接器。梳状驱动器具有第一电容器板和第二电容器板。电容器板具有能够进行数字化的齿。可变形连接器构造成对第一电容器板施加机械恢复力。可变形连接器被配置为响应于不跨越电容器施加控制电压而将第一电容器板恢复到平衡静止位置。梳齿驱动器在平衡静止位置比在梳齿驱动器的机械稳定性阈值处更多地啮合。电容器板在平衡静止位置脱离。

12. 发明申请

US20090104959A1 GAMING DEVICE AND METHOD FOR PROVIDING PLAYER SELECTION OF MODIFIERS TO GAME COMPONENTS 有权
标题翻译：游戏设备和方法，用于提供播放器选择游戏组件的修改器
公开(公告)号：US20090104959A1
公开(公告)日：2009-04-23
申请号：US11877508
申请日：2007-10-23
申请人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
发明人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
IPC分类号： A63F9/24
CPC分类号： G07F17/3244 , G07F17/32 , G07F17/3209 , G07F17/3211 , G07F17/3213 , G07F17/3223 , G07F17/3225 , G07F17/3258 , G07F17/326 , G07F17/3262 , G07F17/3267 , G07F17/3293 , G07F17/34
摘要： In one embodiment, the gaming device and method disclosed herein provides a player one or more modifiers to apply to different components or characteristics of a game. In one such embodiment, the gaming device enables a player to selectively apply or associate a plurality of modifiers to a single game component or apply the plurality of modifiers across the plurality of game components. For each game component with at least one applied modifier, the gaming device disclosed herein modifies said game component based on each applied modifier. The gaming device generates any awards based on any modified game components and any unmodified game components and provides any generated awards to the player.
摘要翻译：在一个实施例中，本文公开的游戏设备和方法为游戏者提供一个或多个修改器以应用于游戏的不同组件或特征。在一个这样的实施例中，游戏装置使得玩家能够选择性地将多个修饰符应用于或连接到单个游戏组件，或者跨多个游戏组件应用多个修饰符。对于具有至少一个应用的修饰符的每个游戏组件，本文公开的游戏设备基于每个应用的修饰符修改所述游戏组件。游戏设备基于任何修改的游戏组件和任何未修改的游戏组件产生任何奖励，并向玩家提供任何生成的奖励。

13. 发明申请

US20080193913A1 Diluent, methods of manufacture and use 审中-公开
标题翻译：稀释剂，制造和使用方法
公开(公告)号：US20080193913A1
公开(公告)日：2008-08-14
申请号：US12082376
申请日：2008-04-10
申请人： John Lynch , Alan Weiss
发明人： John Lynch , Alan Weiss
IPC分类号： A01N1/02
CPC分类号： G01N33/54393
摘要： The use of diluent to reduce non-specific drug binding (NSB) provides a simple, flexible and biocompatible way to reduce chemical entity (such as drugs, drug candidates and other small molecules) NSB so that bioassay results may more closely predict the behavior of these compounds in vitro. Additionally, the use of diluent as the chemical entity diluent enhances the predictive nature of data emanating from high throughput drug assays such as Caco-2 drug transport assays, plasma protein drug binding assays, PAMPA assays, permeability assays, and drug solubility assays. The diluent is made by either filtering a selected plasma through an ultrafiltration membrane having nominal molecular weight cutoff of about 30 kD, preferably about 10 kD or below or by selectively adding individual components of a plasma or serum that do not contribute to non-specific binding.
摘要翻译：使用稀释剂来减少非特异性药物结合（NSB）提供了一种简单，灵活和生物相容的方法来减少化学实体（如药物，药物候选物和其他小分子）NSB，以便生物测定结果可以更加密切地预测这些化合物在体外。另外，使用稀释剂作为化学实体稀释剂增强了从高通量药物测定（例如Caco-2药物转运测定法，血浆蛋白质药物结合测定法，PAMPA测定法，渗透性测定法和药物溶解度测定）中发出的数据的预测性质。稀释剂通过将选定的血浆过滤通过具有约30kD，优选约10kD或更低的标称分子量截留值的超滤膜或通过选择性加入不对非特异性结合有贡献的血浆或血清的各成分来制备。

14. 发明授权

US07257526B1 Discrete event parallel simulation 有权
标题翻译：离散事件并行仿真
公开(公告)号：US07257526B1
公开(公告)日：2007-08-14
申请号：US09543284
申请日：2000-04-05
申请人： Boris Dmitrievich Lubachevsky , Alan Weiss
发明人： Boris Dmitrievich Lubachevsky , Alan Weiss
IPC分类号： G06G17/50 , G06G17/10 , G06F9/46
CPC分类号： G06F17/5009
摘要： An efficient parallel event simulation method is implemented by simulating blocks of M edge events, where M is approximately equal to e logeN, and N being the number of interconnected processing elements. Following a simulation iteration, each processing element shares information with adjacent processing elements that relates to events that the processing elements simulated which may affect the simulation of events at the neighbor processing elements. When the communication reveals that the information that is shared by a neighbor processing elements is different from the information that the processing element assumed, then the arriving information is kept and the simulation process is repeated. In executing the repeated simulations of a block, the same random variable values are employed. When all of the processing elements find that the arriving shared information is the same as the information already known to the receiving processing element, simulation of the block ends. A new simulation floor is ascertained, and another block of event is simulated.
摘要翻译：通过模拟M边缘事件的块来实现有效的并行事件模拟方法，其中M近似等于e log N，N是互连处理元件的数量。在模拟迭代之后，每个处理元件与相关处理元件共享信息，这些处理元件涉及可以影响相邻处理元件上的事件的模拟的处理元件被模拟的事件。当通信显示由相邻处理元件共享的信息与处理元件假设的信息不同时，保持到达的信息并重复模拟处理。在执行块的重复模拟时，采用相同的随机变量值。当所有处理元件发现到达的共享信息与接收处理元件已知的信息相同时，块的模拟结束。确定了新的模拟层，并且模拟了另一块事件。

15. 发明申请

US20120315980A1 GAMING DEVICE AND METHOD FOR PROVIDING PLAYER SELECTION OF MODIFIERS TO GAME COMPONENTS 有权
公开(公告)号：US20120315980A1
公开(公告)日：2012-12-13
申请号：US13571205
申请日：2012-08-09
申请人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
发明人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
IPC分类号： A63F13/08
CPC分类号： G07F17/3244 , G07F17/32 , G07F17/3209 , G07F17/3211 , G07F17/3213 , G07F17/3223 , G07F17/3225 , G07F17/3258 , G07F17/326 , G07F17/3262 , G07F17/3267 , G07F17/3293 , G07F17/34
摘要： In one embodiment, the gaming device and method disclosed herein provides a player one or more modifiers to apply to different components or characteristics of a game. In one such embodiment, the gaming device enables a player to selectively apply or associate a plurality of modifiers to a single game component or apply the plurality of modifiers across the plurality of game components. For each game component with at least one applied modifier, the gaming device disclosed herein modifies said game component based on each applied modifier. The gaming device generates any awards based on any modified game components and any unmodified game components and provides any generated awards to the player.

16. 发明授权

US08262455B2 Gaming device and method for providing player selection of modifiers to game components 有权
标题翻译：游戏装置和方法，用于向游戏组件提供玩家选择修饰符
公开(公告)号：US08262455B2
公开(公告)日：2012-09-11
申请号：US11877508
申请日：2007-10-23
申请人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
发明人： Scott A. Caputo , Carl V. Kniesteadt , Alan Weiss
IPC分类号： A63F9/24 , A63F13/00 , G06F17/00 , G06F19/00
CPC分类号： G07F17/3244 , G07F17/32 , G07F17/3209 , G07F17/3211 , G07F17/3213 , G07F17/3223 , G07F17/3225 , G07F17/3258 , G07F17/326 , G07F17/3262 , G07F17/3267 , G07F17/3293 , G07F17/34
摘要： In one embodiment, the gaming device and method disclosed herein provides a player one or more modifiers to apply to different components or characteristics of a game. In one such embodiment, the gaming device enables a player to selectively apply or associate a plurality of modifiers to a single game component or apply the plurality of modifiers across the plurality of game components. For each game component with at least one applied modifier, the gaming device disclosed herein modifies said game component based on each applied modifier. The gaming device generates any awards based on any modified game components and any unmodified game components and provides any generated awards to the player.
摘要翻译：在一个实施例中，本文公开的游戏设备和方法为游戏者提供一个或多个修改器以应用于游戏的不同组件或特征。在一个这样的实施例中，游戏装置使得玩家能够选择性地将多个修饰符应用于或连接到单个游戏组件，或者跨多个游戏组件应用多个修饰符。对于具有至少一个应用的修饰符的每个游戏组件，本文公开的游戏设备基于每个应用的修饰符修改所述游戏组件。游戏设备基于任何修改的游戏组件和任何未修改的游戏组件产生任何奖励，并向玩家提供任何生成的奖励。

17. 发明申请

US20080044929A1 Diluent, methods of manufacturing and use 审中-公开
标题翻译：稀释剂，制造和使用方法
公开(公告)号：US20080044929A1
公开(公告)日：2008-02-21
申请号：US11975768
申请日：2007-10-22
申请人： John Lynch , Alan Weiss
发明人： John Lynch , Alan Weiss
IPC分类号： G01N33/536
CPC分类号： G01N33/54393
摘要： The use of diluent to reduce non-specific,drug binding (NSB) provides a simple, flexible and biocompatible way to reduce chemical entity (such as drugs, drug candidates and other small molecules) NSB so that bioassay results may more closely predict the behavior of these compounds in vitro. Additionally, the use of diluent as the chemical entity diluent enhances the predictive nature of data emanating from high throughput drug assays such as Caco-2 drug transport assays, plasma protein drug binding assays, PAMPA assays, permeability assays, and drug solubility assays. The diluent is made by either filtering a selected plasma through an ultrafiltration membrane having nominal molecular weight cutoff of about 30 kD, preferably about 10 kD or below or by selectively adding individual components of a plasma or serum that do not contribute to non-specific binding.
摘要翻译：使用稀释剂降低非特异性，药物结合（NSB）提供了一种简单，灵活和生物相容的方法来减少化学实体（如药物，药物候选物和其他小分子）NSB，以便生物测定结果可能更密切地预测行为的这些化合物。另外，使用稀释剂作为化学实体稀释剂增强了从高通量药物测定（例如Caco-2药物转运测定法，血浆蛋白质药物结合测定法，PAMPA测定法，渗透性测定法和药物溶解度测定）中发出的数据的预测性质。稀释剂通过将选定的血浆过滤通过具有约30kD，优选约10kD或更低的标称分子量截留值的超滤膜或通过选择性加入不对非特异性结合有贡献的血浆或血清的各成分来制备。

18. 发明申请

US20060222688A1 Disposable gloves 审中-公开
标题翻译：一次性手套
公开(公告)号：US20060222688A1
公开(公告)日：2006-10-05
申请号：US11397520
申请日：2006-04-04
申请人： Alan Weiss , Paul Bottcher
发明人： Alan Weiss , Paul Bottcher
IPC分类号： A61K9/70
CPC分类号： A41D19/0058 , A41D2400/52 , A61B42/00 , A61B42/60
摘要： A disposable glove for a hand of a human wearer that comprises a blend of polyisoprene and another non-latex glove material. The glove provides a fit and feel comparable to a latex glove, while maintaining cost-effectiveness.
摘要翻译：一种人造皮手套的一次性手套，其包括聚异戊二烯与另一非胶乳手套材料的混合物。手套提供适合和感觉与乳胶手套相当，同时保持成本效益。

19. 发明申请

US20050266577A1 Ultrafiltration device for drug binding studies 审中-公开
标题翻译：用于药物结合研究的超滤装置
公开(公告)号：US20050266577A1
公开(公告)日：2005-12-01
申请号：US11195517
申请日：2005-08-02
申请人： John Lynch , Michele Dumon , Alan Weiss , Kenneth Desilets , Stephane Olivier
发明人： John Lynch , Michele Dumon , Alan Weiss , Kenneth Desilets , Stephane Olivier
IPC分类号： G01N33/48 , B01D61/18 , B01D63/08 , B01L3/00 , G01N1/40 , G01N33/15 , G01N33/00
CPC分类号： G01N1/4005 , B01D61/18 , B01D63/081 , B01D2315/08 , B01L3/50255 , B01L2200/0631 , B01L2300/0829 , G01N2001/4016
摘要： The combination of a supported UF membrane having low non-specific binding (NSB) and high protein retention of the tested chemical entity (CE) in a device that is SBS complaint. The membrane is heat sealed to form one or more integral wells that are used to reduce NSB and improve protein retention and provides a simple, flexible way to reduce CE, such as drug and drug candidate (and other small molecule) NSB so that drug binding studies may more closely predict the behavior of these compounds in vivo.
摘要翻译：在SBS投诉的装置中，具有低非特异性结合（NSB）的支持的UF膜和测试化学实体（CE）的高蛋白质保留的组合。膜被热密封以形成一个或多个用于减少NSB并改善蛋白质保留的整合孔，并提供简单，灵活的方式来减少CE，例如药物和药物候选物（和其他小分子）NSB，使得药物结合研究可能更密切地预测这些化合物在体内的行为。

20. 发明授权

US5564943A Electric socket convertor 失效
标题翻译：电插座转换器
公开(公告)号：US5564943A
公开(公告)日：1996-10-15
申请号：US451492
申请日：1995-05-26
申请人： Alan Weiss
发明人： Alan Weiss
IPC分类号： H01R31/06 , H01R33/05 , H01R33/00
CPC分类号： H01R31/06 , H01R33/05
摘要： An electric socket convertor comprises a convertor plug receivable into a conventional electric light bulb socket. An electric convertor socket is connectable with a conventional electric cigarette lighter. A connecting mechanism electrically connects the convertor plug to the convertor socket, such that electric current at the conventional electric light bulb socket is conducted through the convertor plug to the convertor socket. An electric cigarette lighter is inserted into the convertor socket, and is thereby provided with a source of 12-volt D.C. Other portable electric devices similarly can be provided with 12-volt D.C. The electric socket convertor provides convenient access to 12-volt D.C. for numerous electrical devices, and obviates permanent electric socket installation.
摘要翻译：电插座转换器包括可接收到常规电灯泡插座中的转换器插头。电动转换器插座可与常规电动点烟器连接。连接机构将转换器插塞电连接到转换器插座，使得常规电灯泡插座处的电流通过转换器插头传导到转换器插座。电动点烟器插入转换器插座，由此提供12伏直流电源其他便携式电气设备类似地可以提供12伏直流电插座转换器可方便地访问12伏直流电电气设备，并避免永久性电插座安装。

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