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11. 发明申请

US20050222247A1 Chroman derivatives 审中-公开
标题翻译：色原衍生物
公开(公告)号：US20050222247A1
公开(公告)日：2005-10-06
申请号：US10996230
申请日：2004-11-23
申请人： Stephen Boyer , Kentaro Hashimoto , Thomas Rolle , Peter Sandner , Beatrix Stelte-Ludwig , Hanna Tinel , Kerstin Henninger , Arnel Concepcion , Osamu Sakurai , Kanako Hirai , Tadashi Inoue , Yuki Mochizuki , Noriko Nunami , Masaomi Tajimi , Noriyuki Yamamoto , Yasuhiro Tsukimi
发明人： Stephen Boyer , Kentaro Hashimoto , Thomas Rolle , Peter Sandner , Beatrix Stelte-Ludwig , Hanna Tinel , Kerstin Henninger , Arnel Concepcion , Osamu Sakurai , Kanako Hirai , Tadashi Inoue , Yuki Mochizuki , Noriko Nunami , Masaomi Tajimi , Noriyuki Yamamoto , Yasuhiro Tsukimi
IPC分类号： A61K31/353 , A61K31/403 , A61K31/4192 , C07D311/58 , C07D405/12 , C07D311/74
CPC分类号： C07D311/58 , C07D405/12
摘要： This invention relates to chroman derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The chroman derivatives of the present invention have an excellent activity as BETA 3 antagonists and are useful for the prophylaxis and treatment of diseases associated with BETA 3 activity, in particular for the treatment of urological disorder or disease, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; and inflammatory disorders, such as asthma and COPD.
摘要翻译：本发明涉及可用作药物制剂的活性成分的苯并二氢吡喃衍生物及其盐。本发明的苯并二氢吡喃衍生物作为BETA 3拮抗剂具有优异的活性，可用于预防和治疗与BETA 3活性相关的疾病，特别是用于治疗泌尿系统疾病或疾病，如逼尿肌过度活动（膀胱过度活动症），尿失禁，神经源性逼尿肌反应性（逼尿肌hyperflexia），特发性逼尿肌过度活动（逼尿肌不稳定），良性前列腺增生和下尿路症状; 和炎症性疾病，如哮喘和COPD。

12. 发明授权

US5835093A Audio equipment and method of displaying operation thereof 失效
标题翻译：音频设备及其操作方法
公开(公告)号：US5835093A
公开(公告)日：1998-11-10
申请号：US893589
申请日：1997-07-14
申请人： Kaneaki Fujishita , Osamu Sakurai , Junichi Nagahara
发明人： Kaneaki Fujishita , Osamu Sakurai , Junichi Nagahara
IPC分类号： G11B27/024 , G11B27/028 , G11B27/34 , G11B27/36 , G11B31/00 , G11B33/10 , H04H60/04 , H04N5/445 , H04N5/60 , H04N5/765 , H04N21/431 , H04N21/47 , H04N21/485 , H04S3/00 , H04S7/00 , G09G5/08
CPC分类号： H04N21/485 , G11B27/028 , G11B27/34 , G11B27/36 , G11B31/00 , G11B33/10 , H04H60/04 , H04N21/4316 , H04N21/47 , H04N5/44513 , H04N5/44582 , H04N5/60 , H04S7/40 , G11B27/024 , H04N5/445 , H04N5/765 , H04S3/00
摘要： The present invention is concerned with an audio equipment capable of processing video signals and a method of displaying operation of the acoustic equipment. An input selector switch 1 is supplied with reproduced audio signals from devices connected to a tuner unit 2 and input terminals 3, and supplies a signal to a sound field processing DSP unit 4. A signal processed by the DSP unit 4 is applied through a muting switch 5 to an output terminal 6. An input selector switch 7 is supplied with reproduced video signals from devices connected to input terminals 8, and supplies a signal to a graphic controller (GDC) 9 which generates a video signal to display an image. One of a signal generated by the GDC 9 and an original video signal are selected by a switch 10, and applied to an output terminal 11. The GDC 9 also generates an image simulating a control panel. When a key switch 13 is operated, the display corresponding to the operated key in the simulating image is varied.
摘要翻译：本发明涉及能够处理视频信号的音频设备和显示声学设备的操作的方法。向输入选择开关1提供来自连接到调谐器单元2和输入端3的设备的再现音频信号，并将信号提供给声场处理DSP单元4.由DSP单元4处理的信号通过静音开关5连接到输出端子6.输入选择开关7从连接到输入端子8的装置提供再现的视频信号，并将信号提供给图形控制器（GDC）9，图形控制器（GDC）9产生视频信号以显示图像。由GDC9产生的信号和原始视频信号之一由开关10选择，并被施加到输出端11.GDC 9还产生模拟控制面板的图像。当键开关13被操作时，与模拟图像中的操作键对应的显示被改变。

13. 发明授权

US08703721B2 Arylalkylamine compound and process for preparing the same 有权
标题翻译：芳烷基胺化合物及其制备方法
公开(公告)号：US08703721B2
公开(公告)日：2014-04-22
申请号：US13106539
申请日：2011-05-12
申请人： Hiroshi Miyazaki , Junko Tsubakimoto , Kosuke Yasuda , Iwao Takamuro , Osamu Sakurai , Tetsuya Yanagida , Yutaka Hisada
发明人： Hiroshi Miyazaki , Junko Tsubakimoto , Kosuke Yasuda , Iwao Takamuro , Osamu Sakurai , Tetsuya Yanagida , Yutaka Hisada
IPC分类号： C07D205/04 , C07D207/14 , C07D207/16 , C07D207/27 , C07D207/327 , C07D207/335 , C07D207/34 , C07D211/56 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/06 , C07D403/04 , C07D403/10 , C07D405/12 , C07D409/06 , C07D409/12 , C07D417/04 , C07D417/06 , C07D413/12 , A61P5/30 , A61P5/18 , C07H15/26 , A61K31/5377 , A61K31/4545 , A61K31/451 , A61K31/427 , A61K31/501 , A61K31/506 , A61K31/4439 , A61K31/402 , A61K31/7056 , A61K31/5415 , A61K31/397
CPC分类号： C07D207/14 , C07D205/04 , C07D207/16 , C07D207/27 , C07D207/327 , C07D207/335 , C07D207/34 , C07D211/56 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/06 , C07D403/10 , C07D405/12 , C07D409/06 , C07D409/12 , C07D417/04 , C07D417/06 , C07H17/02
摘要： The present invention relates to an arylalkylamine compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, a process for preparing the same, and use of the above-mentioned compound as an activating compound (CaSR agonist) of a Ca sensing receptor, a pharmaceutical composition containing the above-mentioned compound as an effective ingredient, etc.
摘要翻译：本发明涉及由下式[I]表示的芳基烷基胺化合物或其药学上可接受的盐，其制备方法，以及使用上述化合物作为Ca感应的活化化合物（CaSR激动剂）受体，含有上述化合物作为有效成分的药物组合物等

14. 发明申请

US20070225296A1 Arylalkylamine Compound and Process for Preparing the Same 有权
公开(公告)号：US20070225296A1
公开(公告)日：2007-09-27
申请号：US11597966
申请日：2005-05-27
申请人： Hiroshi Miyazaki , Junko Tsubakimoto , Kosuke Yasuda , Iwao Takamuro , Osamu Sakurai , Tetsuya Yanagida , Yutaka Hisada
发明人： Hiroshi Miyazaki , Junko Tsubakimoto , Kosuke Yasuda , Iwao Takamuro , Osamu Sakurai , Tetsuya Yanagida , Yutaka Hisada
IPC分类号： A61K31/497 , A61K31/40 , A61K31/505 , C12Q1/02 , A61K31/44
CPC分类号： C07D207/14 , C07D205/04 , C07D207/16 , C07D207/27 , C07D207/327 , C07D207/335 , C07D207/34 , C07D211/56 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/06 , C07D403/10 , C07D405/12 , C07D409/06 , C07D409/12 , C07D417/04 , C07D417/06 , C07H17/02
摘要： The present invention relates to an arylalkylamine compound represented by the following formula [I] or a pharmaceutically acceptable salt thereof, a process for preparing the same, and use of the above-mentioned compound as an activating compound (CaSR agonist) of a Ca sensing receptor, a pharmaceutical composition containing the above-mentioned compound as an effective ingredient, etc. The symbols in the formula represent the following meanings: Ar: optionally substituted aryl or optionally substituted heteroaryl here, the cyclic portion of the heteroaryl is bicyclic heterocyclic ring in which 5- to 6-membered monocyclic heterocyclic ring containing 1 or 2 hetero atom(s) and benzene ring are fused; R1: a group selected from the group consisting of optionally substituted cyclic hydrocarbon group, and optionally substituted heterocyclic group; n: an integer of 1 to 3; X: single bonding arm, —CH2—, —CO—, —(CH2)m—CO—, —CH(R2)—CO—, —(CH2)p—Y—(C(R3)(R4))q—CO—, —NH—CO— or —N(R5)—CO—; in the above-mentioned respective definitions of the X, the bonding arm described at the left end represents a bond with R1; m is an integer of 1 to 3; p is an integer of 0 to 2; q is an integer of 0 to 2; Y: —O— or —SO2—; R2: phenyl or lower alkyl; R3, R4: each independently represents hydrogen atom or lower alkyl; R5: lower alkyl; provided that the ring portion of the group represented by R1 is neither naphthylidine nor partially saturated group thereof, and, when X is —CH2— or —CO—, R1 is not naphthyl.

15. 发明申请

US20060257441A1 Natural essential oil sanitary insect pest repellent and its use 审中-公开
标题翻译：天然精油卫生防虫驱虫剂及其用途
公开(公告)号：US20060257441A1
公开(公告)日：2006-11-16
申请号：US11125204
申请日：2005-05-10
申请人： Koichiro Komai , Satoko Hayase , Osamu Hayase , Masayasu Miwata , Osamu Sakurai , Osamu Kuroki , Masaaki Mizuguchi , Michiyo Ichihara
发明人： Koichiro Komai , Satoko Hayase , Osamu Hayase , Masayasu Miwata , Osamu Sakurai , Osamu Kuroki , Masaaki Mizuguchi , Michiyo Ichihara
IPC分类号： A01N25/00 , A01N65/00
CPC分类号： A01N65/20 , A01N25/04
摘要： [Object] This invention provides a dispersion containing an insect pest repellent active substance, and an adhesive or bond, ink, resin pellets, a resin product, and a sheet or a film which can exhibit a long term repellent active effect by the particles carrying the dispersion. [Means for achieving the object] The invention also concerns with a natural essential oil having a sanitary pest repellent activity; a dispersion containing, as an active component, at least one of: a first fraction of copaiba oil given by silica gel column chromatography using hexane as an elution solvent, a second fraction given by silica gel column chromatography using a 4:4:1 mixture of hexane/chloroform/ethyl acetate as an elution solvent, and a third fraction given by fractionating the remnant of the second fraction using a 1:1 mixture of ethyl acetate/chloroform as an elution solvent; a dispersion thereof containing a sedimentation inhibitor, particles carrying these dispersions, and a sanitary insect pest repellent active adhesive or bond, ink, resin pellets, resin particles, resin product, sheet or film, and device containing the same.
摘要翻译：本发明提供一种含有昆虫驱避活性物质的分散体，以及粘合剂或粘合剂，油墨，树脂颗粒，树脂产品和片材或膜，其可以通过携带的颗粒表现出长期驱避活性作用分散体。实现该目的的手段本发明还涉及具有卫生防虫活性的天然精油; 作为活性成分的分散液含有以下物质中的至少一种：通过硅胶柱色谱法，使用己烷作为洗脱溶剂，得到的第一馏分油，通过硅胶柱色谱法使用4:4:1混合物的己烷/氯仿/乙酸乙酯作为洗脱溶剂，第三馏分通过使用1:1的乙酸乙酯/氯仿混合物作为洗脱溶剂分馏第二馏分的残留物; 其含有沉降抑制剂的分散体，携带这些分散体的颗粒，以及卫生防虫驱虫剂活性粘合剂或粘合剂，油墨，树脂颗粒，树脂颗粒，树脂产品，片材或薄膜以及含有它们的装置。

16. 发明授权

US5818418A Audio equipment and method of displaying operation thereof 失效
公开(公告)号：US5818418A
公开(公告)日：1998-10-06
申请号：US867039
申请日：1997-06-04
申请人： Kaneaki Fujishita , Osamu Sakurai , Junichi Nagahara
发明人： Kaneaki Fujishita , Osamu Sakurai , Junichi Nagahara
IPC分类号： G11B27/024 , G11B27/028 , G11B27/34 , G11B27/36 , G11B31/00 , G11B33/10 , H04H60/04 , H04N5/445 , H04N5/60 , H04N5/765 , H04N21/431 , H04N21/47 , H04N21/485 , H04S3/00 , H04S7/00 , G09G5/08
CPC分类号： H04N21/485 , G11B27/028 , G11B27/34 , G11B27/36 , G11B31/00 , G11B33/10 , H04H60/04 , H04N21/4316 , H04N21/47 , H04N5/44513 , H04N5/44582 , H04N5/60 , H04S7/40 , G11B27/024 , H04N5/445 , H04N5/765 , H04S3/00
摘要： The present invention is concerned with an audio equipment capable of processing video signals and a method of displaying operation of the acoustic equipment. An input selector switch 1 is supplied with reproduced audio signals from devices connected to a tuner unit 2 and input terminals 3, and supplies a signal to a sound field processing DSP unit 4. A signal processed by the DSP unit 4 is applied through a muting switch 5 to an output terminal 6. An input selector switch 7 is supplied with reproduced video signals from devices connected to input terminals 8, and supplies a signal to a graphic controller (GDC) 9 which generates a video signal to display an image. One of a signal generated by the GDC 9 and an original video signal are selected by a switch 10, and applied to an output terminal 11. The GDC 9 also generates an image simulating a control panel. When a key switch 13 is operated, the display corresponding to the operated key in the simulating image is varied.

17. 发明授权

US5416535A Remote control system and control method 失效
标题翻译：遥控系统及控制方法
公开(公告)号：US5416535A
公开(公告)日：1995-05-16
申请号：US183835
申请日：1994-01-21
申请人： Kazuhiro Sato , Osamu Sakurai
发明人： Kazuhiro Sato , Osamu Sakurai
IPC分类号： G11B31/00 , G11B15/02 , G11B19/02 , H04B1/20 , H04N5/00 , H04Q9/00 , H04N5/50 , H04N5/268
CPC分类号： H04N5/44582 , G11B15/023 , G11B19/02 , H04B1/202 , G08C2201/32 , H04N21/47
摘要： A remote control system comprises an audio apparatus audio signal, a video apparatus, a remote input device, a selector, and an output device wherein the remote input device transmits a position specification signal to the selector. The selector is connected to the audio and video apparatus and receives the position specification signal from the remote input device. The memory portion stores picture data include mode setting data for setting operation modes of the audio and video apparatus, command codes associated with the operation modes, and selection picture data for selecting the audio apparatus or Video apparatus. When the control portion detects that the position specification signal input by the remote input device indicates a predetermined position, it reads picture data in accordance with the input position specification signal from the memory portion. The command generation portion then selectively supplies a command code to the audio apparatus or video apparatus in accordance with the input position specification signal. The output device has a display portion to which the picture data read by the control portion from the memory portion are supplied, and the output signal of either the audio apparatus or video apparatus selected by the selector is supplied to the output device. When the control portion of the selector detects that the position specification signal input by the remote input device is a signal indicating the position corresponding to any one of the four sides of the display portion with the picture data of either the audio apparatus or video apparatus displayed on the display device, either the picture data associated with the other apparatus or the selection picture data are read from the memory portion and are displayed on said display portion.
摘要翻译：遥控系统包括音频设备音频信号，视频设备，远程输入设备，选择器和输出设备，其中远程输入设备向选择器发送位置指定信号。选择器连接到音频和视频设备，并从远程输入设备接收位置指定信号。存储部分存储图像数据，包括用于设置音频和视频装置的操作模式的模式设置数据，与操作模式相关联的命令代码以及用于选择音频装置或视频装置的选择图像数据。当控制部分检测到由远程输入设备输入的位置指定信号指示预定位置时，它根据来自存储器部分的输入位置指定信号读取图像数据。然后，命令产生部分根据输入位置指定信号选择性地向音频设备或视频设备提供命令代码。输出装置具有显示部分，由控制部分从存储器部分读取的图像数据被提供给显示部分，并且由选择器选择的音频装置或视频装置的输出信号被提供给输出装置。当选择器的控制部分检测到由远程输入装置输入的位置指定信号是指示与显示部分的四个边中的任何一个相对应的位置的信号，其中显示音频装置或视频装置的图像数据在显示装置上，与其他装置相关联的图像数据或选择图像数据从存储器部分读取并显示在所述显示部分上。

18. 发明授权

US5060619A Electrostatic capacity type fuel concentration monitoring unit with temperature dependent fluctuation compensating feature 失效
标题翻译：具有温度依赖波动补偿特性的静电容量型燃料浓度监测装置
公开(公告)号：US5060619A
公开(公告)日：1991-10-29
申请号：US611276
申请日：1990-11-09
申请人： Osamu Sakurai , Kazumitsu Kobayashi , Hideki Kano , Kiyoshi Takeuchi
发明人： Osamu Sakurai , Kazumitsu Kobayashi , Hideki Kano , Kiyoshi Takeuchi
IPC分类号： G01N27/60 , F02D19/08 , G01N27/22 , G01N27/406
CPC分类号： G01N27/4065 , F02D19/0628 , F02D19/084 , F02D19/087 , F02D2200/0606 , F02D2200/0611 , Y02T10/36
摘要： A fuel concentration monitoring unit includes a fuel temperature dependent error correction circuit in the unit. A fuel concentration indicative voltage signal variation rate set with taking a specific fuel concentration as reference point. The output incorporated in the unit.
摘要翻译：燃料浓度监测单元包括在该单元中的与燃料温度相关的误差校正电路。以特定燃料浓度为参考点设定的指示电压信号变化率的燃料浓度。输出结合在单元中。

19. 发明授权

US4131779A High-frequency heating apparatus 失效
标题翻译：高频加热装置
公开(公告)号：US4131779A
公开(公告)日：1978-12-26
申请号：US813418
申请日：1977-07-06
申请人： Osami Tatsukawa , Osamu Sakurai , Hisayuki Serizawa
发明人： Osami Tatsukawa , Osamu Sakurai , Hisayuki Serizawa
IPC分类号： H05B6/68 , H05B6/80 , H05B9/06
CPC分类号： H05B6/642 , H05B6/645
摘要： The present invention involves a high-frequency heating apparatus of the type which comprises a heating chamber for accommodating an object to be heated, a door openably and closably provided for an opening of the heating chamber, a high-frequency energy generator for supplying high-frequency energy to the interior of the heating chamber, a fan for forcibly ventilating the interior of the heating chamber, and a heating chamber air-outlet cooperative with the fan to effect the forcible ventilation for the interior of the heating chamber. Temperature of air flowing out of heating chamber through the heating chamber air-outlet is detected by a temperature sensor to actuate an automatic heating control unit for controlling the supply of high-frequency energy. The apparatus is also provided with a manual heating control unit for manually controlling the heating time. In response to a selective operation of one of the automatic heating control unit and the manual heating control unit, an air flow path changer is actuated to change a part of the flow path of the air for ventilating the interior of the heating chamber.
摘要翻译：本发明涉及一种高频加热装置，其特征在于，包括用于容纳被加热物的加热室，可开闭地设置在加热室的开口部的门，高频能量发生器，向加热室内部施加频率的能量，用于强制地使加热室内部通风的风扇和与风扇协调的加热室出气口，以对加热室的内部进行强制通风。通过温度传感器检测通过加热室出气口流出加热室的空气的温度，以启动用于控制高频能量供应的自动加热控制单元。该装置还设置有用于手动控制加热时间的手动加热控制单元。响应于自动加热控制单元和手动加热控制单元之一的选择性操作，致动空气流路改变器以改变用于使加热室内部通风的空气的流路的一部分。

20. 发明申请

US20130261128A1 CONTINUOUS ARYCYCLIC COMPOUND 有权
标题翻译：连续的芳香化合物
公开(公告)号：US20130261128A1
公开(公告)日：2013-10-03
申请号：US13994543
申请日：2011-12-16
申请人： Osamu Sakurai , Kunio Saruta , Norimitsu Hayashi , Takashi Goi , Kenji Morokuma , Hidekazu Tsujishima , Hiroaki Sawamoto , Hiroaki Shitama , Ritsuo Imashiro
发明人： Osamu Sakurai , Kunio Saruta , Norimitsu Hayashi , Takashi Goi , Kenji Morokuma , Hidekazu Tsujishima , Hiroaki Sawamoto , Hiroaki Shitama , Ritsuo Imashiro
IPC分类号： C07D233/64 , C07D401/10 , C07D403/10 , C07D401/14 , C07D405/14 , C07D401/04 , C07D403/04
CPC分类号： C07D401/04 , C07D233/64 , C07D401/10 , C07D401/14 , C07D403/04 , C07D403/10 , C07D405/14
摘要： This is to provide a continuous arycyclic compound having a DGAT1 inhibitory activity, and useful for prophylaxis and/or treatment of obesity or hyperlipidemia caused by obesity, hypertriglyceridemia, lipid metabolism disorder, fatty liver, hypertension, arteriosclerosis, diabetes, etc., as well as to provide a DGAT1 inhibitor comprising the continuous arycyclic compound or a pharmaceutically acceptable salt thereof as an effective ingredient. Disclosed is the continuous arycyclic compound is represented by the formula: wherein the substituents in the formula are the same as defined in the specification, or a pharmaceutically acceptable salt thereof.
摘要翻译：这是提供具有DGAT1抑制活性的连续的芳环化合物，并且可用于预防和/或治疗由肥胖，高甘油三酯血症，脂质代谢障碍，脂肪肝，高血压，动脉硬化，糖尿病等引起的肥胖症或高脂血症，以及以提供包含连续的芳环化合物或其药学上可接受的盐作为有效成分的DGAT1抑制剂。公开了连续的芳环化合物由下式表示：其中式中的取代基与说明书中所定义的相同，或其药学上可接受的盐。

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