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11. 发明授权

US09138583B2 Method and system for determining pacing settings 有权
标题翻译：确定起搏设置的方法和系统
公开(公告)号：US09138583B2
公开(公告)日：2015-09-22
申请号：US13596585
申请日：2012-08-28
申请人： Nils Holmstrom , Andreas Karlsson
发明人： Nils Holmstrom , Andreas Karlsson
IPC分类号： A61N1/362 , A61N1/365 , A61N1/37 , A61N1/368
CPC分类号： A61N1/36585 , A61N1/365 , A61N1/36514 , A61N1/3682 , A61N1/3704
摘要： Systems and methods for optimizing the stimulation of a heart of a patient are disclosed herein. The method comprises delivering pacing therapy to the patient according to a pacing therapy setting schedule, using specific pacing intervals via specific electrode configurations. Further, sinus rate values are recorded over at least one cardiac cycle at each pacing therapy setting and it is determined whether a sinus rate value satisfies predetermined measurement conditions, wherein sinus rate values are used for trending the sinus rate over time if the measurement conditions are satisfied. The accepted sinus rate values, i.e. values that satisfy the measurement conditions, are trended over time, wherein each trended sinus rate value is created based on recordings from at least one cardiac cycle. A preferred pacing therapy setting is determined to be the pacing therapy setting that provides a lowest sinus rate.
摘要翻译：本文公开了用于优化患者心脏刺激的系统和方法。该方法包括根据起搏治疗设置时间表，通过特定电极配置使用特定的起搏间隔向患者输送起搏治疗。此外，在每个起搏治疗设置中，在至少一个心动周期上记录窦速率值，并且确定窦速率值是否满足预定的测量条件，其中如果测量条件是窦性速率值，则使用窦速率值来随着时间推移窦速率满意。接受的窦速率值，即满足测量条件的值随时间趋势，其中每个趋势窦速率值是基于至少一个心动周期的记录创建的。优选的起搏治疗设置被确定为提供最低窦速率的起搏治疗设置。

12. 发明授权

US08863524B2 Burner 有权
标题翻译：刻录机
公开(公告)号：US08863524B2
公开(公告)日：2014-10-21
申请号：US12935919
申请日：2009-03-26
申请人： Andreas Karlsson , Vladimir Milosavljevic
发明人： Andreas Karlsson , Vladimir Milosavljevic
IPC分类号： F23R3/14 , F23R3/28 , F23R3/34
CPC分类号： F23R3/286 , F23D2900/00014 , F23R3/343 , F23R3/346
摘要： A burner for a gas turbine including a burner housing is provided. Provided is a lean-rich partially premixed low emission burner for a gas turbine combustor providing stable ignition and combustion process at all engine load conditions. At the upstream end of that burner a pilot combustor creates a flow of an unquenched concentration of radicals and heat. Respectively provided is a plurality of quarl sections surrounding the exit of the pilot combustor, a main combustion room defined downstream the pilot combustor and at least a first channel defined as an annular space between an upstream quarl section and the closest downstream quarl section providing air and fuel to a main flame in the combustion room.
摘要翻译：提供一种用于包括燃烧器壳体的燃气轮机的燃烧器。提供了一种用于燃气轮机燃烧器的富稀薄部分预混合的低排放燃烧器，其在所有发动机负载条件下提供稳定的点火和燃烧过程。在该燃烧器的上游端，导向燃烧室产生不消退的自由基和热量的流动。分别设置有围绕导向燃烧室的出口的多个岔区，在主燃烧室下游定义的主燃烧室和至少一个第一通道，其被定义为在上游岔区与最近的下游quar区之间的环形空间，燃烧到燃烧室中的主要火焰。

13. 发明申请

US20140026579A1 BURNER FOR A GAS TURBINE 审中-公开
标题翻译：燃气轮机
公开(公告)号：US20140026579A1
公开(公告)日：2014-01-30
申请号：US13876594
申请日：2011-09-27
申请人： Andreas Karlsson , Magnus Persson
发明人： Andreas Karlsson , Vladimir Dusan Milosavljevic , Magnus Persson
IPC分类号： F23R3/34
CPC分类号： F23R3/343 , F23D2900/00014 , F23D2900/00015 , F23R3/20 , F23R3/286
摘要： A burner for a gas turbine includes a burner housing, and a pilot combustor having a supply module providing pilot fuel and pilot air into a pilot combustion room being enclosed by a pilot combustor housing having a tapered exit with a throat of a defined length into the resulting main flow direction. The throat discharges a concentration of radicals are and heat generated in the pilot combustion room into a main combustion room enclosed by the burner housing. The interior cross section area of the throat deviates from a circle by means of flow guiding elements provided as protrusions with a defined radial height or as recesses with a defined depth extending longitudinally along the direction of the burner axis to give the discharging flow a defined velocity distribution with regard to a circumferential direction.
摘要翻译：一种用于燃气轮机的燃烧器包括燃烧器壳体和引燃燃烧器，其具有向导向燃烧室提供引燃燃料和先导空气的供给模块，该引燃燃烧室由具有限定长度的喉部的具有锥形出口的先导燃烧器壳体包围，主要流向。喉部将先导燃烧室中产生的自由基浓度和热量排放到由燃烧器壳体包围的主燃烧室中。喉部的内部横截面区域通过作为具有限定的径向高度的突起的流动引导元件而偏离圆形，或者具有沿着燃烧器轴线的方向纵向延伸的限定深度的凹部，以使排出流具有限定的速度关于圆周方向的分布。

14. 发明申请

US20120165692A1 IMPLANTABLE MEDICAL DEVICE AND A METHOD FOR USE IN AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗装置和用于可植入医疗装置的方法
公开(公告)号：US20120165692A1
公开(公告)日：2012-06-28
申请号：US13334735
申请日：2011-12-22
申请人： Malin Hollmark , Andreas Karlsson
发明人： Malin Hollmark , Andreas Karlsson
IPC分类号： A61B5/046
CPC分类号： A61B5/6869 , A61B5/046 , A61B5/0538 , A61N1/36521
摘要： An implantable medical device is connectable to at least three electrodes, and includes an immittance measurer that performs immittance measurements within the heart of a patient using at least three electrodes coupled to the device, with at least one of the electrodes is arranged in an atrium of the patient's heart. The medical device further includes an immittance converter that converts the immittance measurement values into individual near-field immittance values of the at least one electrode arranged in an atrium, an atrial dilatation detector that detects atrial dilatation based upon the individual near-field immittance values, and that determines atrial dilatation values in dependence thereon, and an atrial fibrillation risk determiner that determines an atrial fibrillation risk index based upon the atrial dilatation values.
摘要翻译：可植入医疗装置可连接到至少三个电极，并且包括使用至少三个耦合到该装置的电极在患者的心脏内进行导纳测量的导纳测量器，其中至少一个电极被布置在病人的心脏医疗装置还包括将导纳测量值转换成布置在心房中的至少一个电极的单独的近场导纳值的导纳转换器，基于各个近场导纳值来检测心房扩张的心房扩张检测器，并且根据其确定心房扩张值，以及基于心房膨胀值确定心房颤动风险指数的心房颤动风险确定器。

15. 发明申请

US20170102036A1 BEARING CAGE WITH ANTENNA AND METHOD FOR DETECTING FAILURE OF A BEARING CAGE 有权
公开(公告)号：US20170102036A1
公开(公告)日：2017-04-13
申请号：US15278082
申请日：2016-09-28
申请人： Yoann Hebrard , Defeng Lang , Andreas Karlsson , Victor Martinez , Frank de Wit
发明人： Yoann Hebrard , Defeng Lang , Andreas Karlsson , Victor Martinez , Frank de Wit
IPC分类号： F16C41/00 , F16C33/46 , H01Q7/00 , F16C33/56 , G01M13/04 , F16C33/38 , F16C33/44
CPC分类号： F16C41/008 , F16C19/386 , F16C19/52 , F16C33/3831 , F16C33/44 , F16C33/4611 , F16C33/4635 , F16C33/56 , F16C41/002 , F16C2202/40 , F16C2233/00 , F16C2300/02 , G01M13/04 , H01Q1/27 , H01Q7/00
摘要： The invention relates to a bearing cage including a bearing cage main body made of a polymer material and having pockets for receiving at least one row of rolling elements of a bearing. The cage is provided with a passive resonant circuit including an antenna coil attached to the cage main body. It is proposed that the antenna coil is formed as a conductive layer directly attached to the cage material of the bearing cage main body and is designed so as to have a breaking point less than or equal to a breaking point of the cage material. Thus, a rupture in the cage main body ruptures the antenna coil, changing the resonance behaviour of the passive resonant circuit.

16. 发明授权

US08674240B2 Transition frame with integrated compression unit 有权
标题翻译：具有集成压缩单元的过渡框架
公开(公告)号：US08674240B2
公开(公告)日：2014-03-18
申请号：US12735623
申请日：2009-01-21
申请人： Andreas Karlsson , Stefan Milton
发明人： Andreas Karlsson , Stefan Milton
IPC分类号： H02G3/22 , B23P17/04
CPC分类号： H02G3/22 , F16L5/08 , F16L5/14 , Y10T29/49
摘要： A frame for receiving one or more modules for cable entries or pipe penetrations. A compression unit is an integrated part of the frame in at least one embodiment, which compression unit is to compress the modules inside the frame. The compression unit includes three compression wedges. An upper and a lower compression wedge have the same orientation, while a middle compression wedge has an opposite orientation. The middle compression wedge is oriented with a broad side facing an opening of the frame receiving the modules. At least one compression screw goes through openings of the upper and lower compression wedges and through a slot in the middle compression wedge.
摘要翻译：用于接收用于电缆入口或管道穿透的一个或多个模块的框架。在至少一个实施例中，压缩单元是框架的集成部分，该压缩单元将压缩框架内的模块。压缩单元包括三个压缩楔。上压缩楔和下压缩楔具有相同的取向，而中间压缩楔具有相反的取向。中间压缩楔定向成宽面朝向容纳模块的框架的开口。至少一个压缩螺钉穿过上下压缩楔的开口并穿过中间压缩楔的槽。

17. 发明申请

US20130053915A1 METHOD AND SYSTEM FOR DETERMINING PACING SETTINGS 有权
公开(公告)号：US20130053915A1
公开(公告)日：2013-02-28
申请号：US13596585
申请日：2012-08-28
申请人： Nils Holmstrom , Andreas Karlsson
发明人： Nils Holmstrom , Andreas Karlsson
IPC分类号： A61N1/365
CPC分类号： A61N1/36585 , A61N1/365 , A61N1/36514 , A61N1/3682 , A61N1/3704
摘要： Systems and methods for optimizing the stimulation of a heart of a patient are disclosed herein. The method comprises delivering pacing therapy to the patient according to a pacing therapy setting schedule, using specific pacing intervals via specific electrode configurations. Further, sinus rate values are recorded over at least one cardiac cycle at each pacing therapy setting and it is determined whether a sinus rate value satisfies predetermined measurement conditions, wherein sinus rate values are used for trending the sinus rate over time if the measurement conditions are satisfied. The accepted sinus rate values, i.e. values that satisfy the measurement conditions, are trended over time, wherein each trended sinus rate value is created based on recordings from at least one cardiac cycle. A preferred pacing therapy setting is determined to be the pacing therapy setting that provides a lowest sinus rate.

18. 发明授权

US08372864B2 1-oxo-isoindoline-4-carboxamide and 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamide derivatives, preparation and therapeutic use thereof 有权
标题翻译： 1-氧代 - 异吲哚啉-4-甲酰胺和1-氧代-1,2,3,4-四氢异喹啉-5-甲酰胺衍生物，其制备和治疗用途
公开(公告)号：US08372864B2
公开(公告)日：2013-02-12
申请号：US12693597
申请日：2010-01-26
申请人： Bernard Baudoin , Michel Evers , Arielle Genevois-Borella , Andreas Karlsson , Jean-Luc Malleron , Magali Mathieu
发明人： Bernard Baudoin , Michel Evers , Arielle Genevois-Borella , Andreas Karlsson , Jean-Luc Malleron , Magali Mathieu
IPC分类号： A61K31/4035 , A61K31/47 , C07D209/44 , C07D217/24
CPC分类号： C07D209/46 , C07D217/24 , C07D413/12
摘要： The present invention relates to derivatives of 1-oxo-isoindoline-4-carboxamides and of 1-oxo-1,2,3,4-tetrahydroisoquinoline-5-carboxamides, to the preparation thereof and to the therapeutic use thereof.
摘要翻译：本发明涉及1-氧代 - 异吲哚啉-4-甲酰胺和1-氧代-1,2,3,4-四氢异喹啉-5-甲酰胺的衍生物及其制备方法及其治疗用途。

19. 外观设计

USD703033S1 Retaining clamp for a splice box 有权
标题翻译：接线盒固定夹
公开(公告)号：USD703033S1
公开(公告)日：2014-04-22
申请号：US29415548
申请日：2012-03-12
申请人： Andreas Karlsson
设计人： Andreas Karlsson

20. 发明申请

US20130289650A1 Neuromodulation for Hypertension Control 审中-公开
标题翻译：高血压控制神经调节
公开(公告)号：US20130289650A1
公开(公告)日：2013-10-31
申请号：US13456140
申请日：2012-04-25
申请人： Andreas Karlsson , Stuart Rosenberg , John Gustafsson
发明人： Andreas Karlsson , Stuart Rosenberg , John Gustafsson
IPC分类号： A61N1/36
CPC分类号： A61N1/36117
摘要： Neuromodulation for controlling hypertension and other cardio-renal disorders of a patient is disclosed. A neuromodulation device is configured to be delivered to a patient's body and to apply an electric activation to decrease renal sympathetic hyperactivity of the patient based on monitored blood pressure of the patient, substantially without thermal energization of the patient's body by applying the electric activation. The electric activation may also depend on monitored blood volume of the patient. A feedback control module may be used to provide feedback control information for adjusting the electric activation based on the monitored blood pressure and volume of the patient.
摘要翻译：公开了用于控制患者的高血压和其它心脏 - 肾脏疾病的神经调节。神经调节装置被配置为被输送到患者的身体并施加电激活以基于患者的监测的血压来降低患者的肾交感神经活动，基本上通过施加电激活而不能对患者身体进行热激发。电激活也可以取决于患者的监测血容量。可以使用反馈控制模块来提供用于基于所监测的患者的血压和体积来调节电激活的反馈控制信息。

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