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11. 发明授权

US07902511B2 Method of and software for calculating a scatter estimate for tomographic scanning and system for tomographic scanning 失效
标题翻译：用于计算层析扫描的散射估计的方法和软件以及用于层析扫描的系统
公开(公告)号：US07902511B2
公开(公告)日：2011-03-08
申请号：US12518334
申请日：2007-12-18
申请人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
发明人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/164
CPC分类号： G01T1/1647 , G06T11/005
摘要： The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps: determine an estimate of the unscattered events; determine a simulation of the scattered events; determine a value of a scaling factor by fitting the sum of the estimate of the unscattered events and a product of the scaling factor and the simulation of the scattered events to the detection data; and determine the scatter estimate as the product of the scaling factor having said value and the simulation of the scattered events.
摘要翻译：该方法计算用于正电子发射断层摄影扫描仪中来自被摄体的检测数据的散射校正的散射估计。检测数据表示在受试者中发射的湮灭光子的分散事件和不受散射的事件。该方法使用以下步骤：确定未分散事件的估计; 确定分散事件的模拟; 通过将未散射事件的估计和缩放因子的乘积和分散事件的模拟的和拟合到检测数据来确定缩放因子的值; 并将散射估计确定为具有所述值的缩放因子与散射事件的模拟的乘积。

12. 发明申请

US20080224050A1 Method of and Software for Calculating a Scatter Estimate for Tomographic Scanning and System for Tomographic Scanning 失效
标题翻译：用于计算层析扫描的分散估计的方法和软件以及用于层析扫描的系统
公开(公告)号：US20080224050A1
公开(公告)日：2008-09-18
申请号：US11994580
申请日：2006-07-07
申请人： Kris Filip Johan Jules Thielemans , Charalampus Tsoumpas
发明人： Kris Filip Johan Jules Thielemans , Charalampus Tsoumpas
IPC分类号： G01T1/29 , G01T1/00
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1647
摘要： The method calculates a scatter estimate for annihilation photons in a subject having a distribution of attenuation. The method can be used for scatter correction of detection data from a positron emission tomographic scanner. The method uses the following steps: —select a first scatter point S1 and a second scatter point S2, —determine a first scatter probability for scattering of a photon at scatter point S1 and a second scatter probability for scattering of a photon at scatter point S2, —determine an integral of the attenuation over a line connecting S1 and S2, —multiply the integral and the scatter probabilities and use the product in the calculation of the scatter estimate.
摘要翻译：该方法计算具有衰减分布的受试者中的湮灭光子的散射估计。该方法可用于来自正电子发射断层扫描仪的检测数据的散射校正。该方法使用以下步骤： - 选择第一散射点S 1和第二散射点S 2， - 确定用于在散射处散射光子的第一散射概率点S 1和散射点S 2 2处的光子的散射的第二散射概率，确定在连接S 1上的线的衰减的积分， / SUB>和S＆lt; 2＆gt;， - 多项式的积分和散布概率，并在散布估计的计算中使用该乘积。

13. 发明授权

US08569706B2 Method and system for processing gated image data 有权
标题翻译：门控图像数据处理方法及系统
公开(公告)号：US08569706B2
公开(公告)日：2013-10-29
申请号：US13487046
申请日：2012-06-01
申请人： Sheshadri Thiruvenkadam , Rakesh Mullick , Kris Filip Johan Jules Thielemans , Srikrishnan Viswanathan
发明人： Sheshadri Thiruvenkadam , Rakesh Mullick , Kris Filip Johan Jules Thielemans , Srikrishnan Viswanathan
IPC分类号： G01T1/164
CPC分类号： A61B6/037 , A61B6/503 , A61B6/5205 , A61B6/5264 , A61B6/5288
摘要： A method for generating an image is provided. The method comprises: acquiring a first set of image data using a first imaging modality; sorting the first set of image data into a plurality of gates to generate a plurality of gated data sets; reconstructing each gated data set to generate a respective gated image for each gated data set; registering the respective gated images to generate a plurality of registered images; and generating a median image from the plurality of registered images, wherein each voxel of the median image is a respective median value of the corresponding voxels of the plurality of registered images.
摘要翻译：提供了一种用于生成图像的方法。该方法包括：使用第一成像模式获取第一组图像数据; 将第一组图像数据分类成多个门以产生多个门控数据集; 重建每个门控数据集以为每个门控数据集生成相应的门控图像; 注册各个门控图像以生成多个登记图像; 以及从所述多个登记图像生成中值图像，其中所述中值图像的每个体素是所述多个登记图像中的相应体素的相应中值。

14. 发明申请

US20120305780A1 METHOD AND SYSTEM FOR PROCESSING GATED IMAGE DATA 有权
标题翻译：用于处理图像数据的方法和系统
公开(公告)号：US20120305780A1
公开(公告)日：2012-12-06
申请号：US13487046
申请日：2012-06-01
申请人： Sheshadri THIRUVENKADAM , Rakesh Mullick , Kris Filip Johan Jules Thielemans , Srikrishnan Viswanathan
发明人： Sheshadri THIRUVENKADAM , Rakesh Mullick , Kris Filip Johan Jules Thielemans , Srikrishnan Viswanathan
IPC分类号： A61B6/00 , G01T1/164
CPC分类号： A61B6/037 , A61B6/503 , A61B6/5205 , A61B6/5264 , A61B6/5288
摘要： A method for generating an image is provided. The method comprises: acquiring a first set of image data using a first imaging modality; sorting the first set of image data into a plurality of gates to generate a plurality of gated data sets; reconstructing each gated data set to generate a respective gated image for each gated data set; registering the respective gated images to generate a plurality of registered images; and generating a median image from the plurality of registered images, wherein each voxel of the median image is a respective median value of the corresponding voxels of the plurality of registered images.
摘要翻译：提供了一种用于生成图像的方法。该方法包括：使用第一成像模式获取第一组图像数据; 将第一组图像数据分类成多个门以产生多个门控数据集; 重建每个门控数据集以为每个门控数据集生成相应的门控图像; 注册各个门控图像以生成多个登记图像; 以及从所述多个登记图像生成中值图像，其中所述中值图像的每个体素是所述多个登记图像中的相应体素的相应中值。

15. 发明申请

US20120281897A1 METHOD AND APPARATUS FOR MOTION CORRECTING MEDICAL IMAGES 有权
标题翻译：运动校正医学图像的方法和装置
公开(公告)号：US20120281897A1
公开(公告)日：2012-11-08
申请号：US13099558
申请日：2011-05-03
申请人： Pasha Razifar , Kris Filip Johan Jules Thielemans , Shailendra Pratap Singh Rathore
发明人： Pasha Razifar , Kris Filip Johan Jules Thielemans , Shailendra Pratap Singh Rathore
IPC分类号： G06K9/00 , G01T1/164 , A61B6/03 , G01T1/16
CPC分类号： A61B6/037 , A61B6/032 , A61B6/4417 , A61B6/508 , A61B6/5264 , A61B6/5288 , G06T11/005 , G06T2211/412
摘要： A method for reducing, in an image, motion related imaging artifacts includes obtaining an image dataset of a region of interest, generating a plurality of intermediate images using the image dataset, applying a multivariate data analysis technique to the plurality of the intermediate images to generate motion information, sorting the intermediate images into a plurality of bins based on the motion information, and generating an image of the region of interest using at least one of the plurality of bins.
摘要翻译：一种用于在图像中减少运动相关成像伪像的方法包括：获得感兴趣区域的图像数据集，使用该图像数据集生成多个中间图像，向多个中间图像应用多变量数据分析技术以产生运动信息，基于运动信息将中间图像分类成多个箱，以及使用多个箱中的至少一个来生成感兴趣区域的图像。

16. 发明授权

US07756307B2 Method of, and software for, conducting motion correction for a tomographic scanner 失效
标题翻译：用于断层扫描仪进行运动校正的方法和软件
公开(公告)号：US07756307B2
公开(公告)日：2010-07-13
申请号：US10576004
申请日：2004-10-14
申请人： Kris Filip Johan Jules Thielemans
发明人： Kris Filip Johan Jules Thielemans
IPC分类号： G06K9/00 , G01N23/06
CPC分类号： G06T11/005 , A61B6/037 , G06T2211/412
摘要： A method of conducting motion correction for a tomographic scanner including a detector array for detecting radiation to generate detector data. The method comprises storing detector data collected during a data acquisition period, the detector data being indicative of directions along which radiation is detected and quantities of radiation detected in different of said directions. The method involves storing movement data representing movement of the subject during the data acquisition period and motion correcting the detector data using the movement data and a motion correction algorithm to calculate motion corrected detector data. The motion correcting step comprises realigning directions of at least some of said detector data on the basis of said movement data and altering quantities of at least some of said detector data on the basis of said movement data, such that at least some of said detector data are both realigned and altered in quantity due to movement of the subject, some detector data are very small and subject to large noise levels. In these cases, the detector data quantities are altered using calculation of estimates from other, more reliable, detector data.
摘要翻译：对包括用于检测辐射的检测器阵列的断层扫描仪进行运动校正以产生检测器数据的方法。该方法包括存储在数据采集周期期间收集的检测器数据，检测器数据指示检测到辐射的方向和在不同方向上检测到的辐射量。该方法包括存储表示在数据采集周期期间对象的运动的移动数据，并使用运动数据和运动校正算法来运动校正检测器数据，以计算运动校正的检测器数据。所述运动校正步骤包括基于所述移动数据对所述检测器数据中的至少一些的方向进行重新对准，并且基于所述移动数据改变所述检测器数据中的至少一些的量，使得所述检测器数据中的至少一些由于被摄体的移动，它们的数量都被重新调整和改变，一些检测器数据非常小，并且受到较大的噪声水平。在这些情况下，使用来自其他更可靠的检测器数据的估计值来改变检测器数据量。

17. 发明申请

US20100086101A1 METHOD OF AND SOFTWARE FOR CALCULATING A SCATTER ESTIMATE FOR TOMOGRAPHIC SCANNING AND SYSTEM FOR TOMOGRAPHIC SCANNING 失效
标题翻译：计算用于TOMOGRAPHIC扫描的散射估计的方法和软件以及用于TOMOGRAPHIC扫描的系统
公开(公告)号：US20100086101A1
公开(公告)日：2010-04-08
申请号：US12518334
申请日：2007-12-18
申请人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
发明人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： H05G1/60 , G06K9/00
CPC分类号： G01T1/1647 , G06T11/005
摘要： The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps: determine an estimate of the unscattered events; determine a simulation of the scattered events; determine a value of a scaling factor by fitting the sum of the estimate of the unscattered events and a product of the scaling factor and the simulation of the scattered events to the detection data; and determine the scatter estimate as the product of the scaling factor having said value and the simulation of the scattered events.
摘要翻译：该方法计算用于正电子发射断层摄影扫描仪中来自被摄体的检测数据的散射校正的散射估计。检测数据表示在受试者中发射的湮灭光子的分散事件和不受散射的事件。该方法使用以下步骤：确定未分散事件的估计; 确定分散事件的模拟; 通过将未散射事件的估计和缩放因子的乘积和分散事件的模拟的和拟合到检测数据来确定缩放因子的值; 并将散射估计确定为具有所述值的缩放因子与散射事件的模拟的乘积。

18. 发明授权

US08575554B2 Methods and systems for scatter estimation in positron emission tomography 有权
标题翻译：正电子发射断层扫描中散射估计的方法和系统
公开(公告)号：US08575554B2
公开(公告)日：2013-11-05
申请号：US13191205
申请日：2011-07-26
申请人： Hua Qian , Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans
发明人： Hua Qian , Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans
IPC分类号： G01T1/164 , A61B6/00 , G06K9/00
CPC分类号： G01T1/1615 , A61B6/037 , G06T11/005
摘要： Methods and systems for multiple scatter estimation in Positron Emission Tomography (PET) are provided. One method includes determining attenuation sinograms and determining a varying convolution kernel as a function of the attenuation sinograms, wherein the kernel varies in amplitude and width over a radial length of a PET imaging system. The method also includes using the varying convolution kernel to estimate multiple PET scatter.
摘要翻译：提供了正电子发射断层扫描（PET）中多重散射估计的方法和系统。一种方法包括确定衰减正弦图并确定作为衰减正弦图的函数的变化的卷积核，其中所述核在PET成像系统的径向长度上的幅度和宽度上变化。该方法还包括使用变化的卷积核估计多个PET散射。

19. 发明授权

US08472683B2 Motion correction in tomographic images 有权
标题翻译：断层图像中的运动校正
公开(公告)号：US08472683B2
公开(公告)日：2013-06-25
申请号：US12550773
申请日：2009-08-31
申请人： Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans , Evren Asma
发明人： Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans , Evren Asma
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B5/7285 , A61B6/037 , A61B6/5235 , A61B6/5247 , A61B6/541 , G06T5/003 , G06T7/30 , G06T7/33 , G06T11/005 , G06T11/008 , G06T2207/10081 , G06T2207/10084 , G06T2207/10104 , G06T2207/20201 , G06T2207/20221 , G06T2207/30004 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： An imaging method comprises reconstructing gated emission tomography images for a region of interest, adjusting a mismatch between the gated emission tomography images and a computed tomography image of the region of interest, registering the gated emission tomography images, and combining the registered gated emission tomography images to generate motion corrected images.
摘要翻译：一种成像方法包括重建关注区域的门控发射断层摄影图像，调整门控发射断层摄影图像与感兴趣区域的计算机断层摄影图像之间的失配，登记门控发射断层摄影图像，以及组合登记的门控发射断层摄影图像以产生运动校正图像。

20. 发明申请

US20100046821A1 MOTION CORRECTION IN TOMOGRAPHIC IMAGES 有权
标题翻译：图像图像中的运动校正
公开(公告)号：US20100046821A1
公开(公告)日：2010-02-25
申请号：US12550773
申请日：2009-08-31
申请人： Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans , Evren Asma
发明人： Ravindra Mohan Manjeshwar , Kris Filip Johan Jules Thielemans , Evren Asma
IPC分类号： G06K9/00
CPC分类号： A61B6/032 , A61B5/7285 , A61B6/037 , A61B6/5235 , A61B6/5247 , A61B6/541 , G06T5/003 , G06T7/30 , G06T7/33 , G06T11/005 , G06T11/008 , G06T2207/10081 , G06T2207/10084 , G06T2207/10104 , G06T2207/20201 , G06T2207/20221 , G06T2207/30004 , G06T2207/30048 , G06T2207/30061 , G06T2211/412
摘要： An imaging method comprises reconstructing gated emission tomography images for a region of interest, adjusting a mismatch between the gated emission tomography images and a computed tomography image of the region of interest, registering the gated emission tomography images, and combining the registered gated emission tomography images to generate motion corrected images.
摘要翻译：一种成像方法包括重建关注区域的门控发射断层摄影图像，调整门控发射断层摄影图像与感兴趣区域的计算机断层摄影图像之间的失配，登记门控发射断层摄影图像，以及组合登记的门控发射断层摄影图像以产生运动校正图像。

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