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11. 发明授权

US6051236A Composition for optimizing muscle performance during exercise 有权
标题翻译：用于优化运动中肌肉表现的组合
公开(公告)号：US6051236A
公开(公告)日：2000-04-18
申请号：US190885
申请日：1998-11-12
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： A23L1/29 , A23L1/30 , A23L1/305 , A61K31/41 , A61K31/195 , A61K31/59 , A61K31/70 , A61K33/14 , A61K33/42 , A61K35/78
CPC分类号： A23L33/175 , A23L33/105 , A23L33/40
摘要： A nutritional composition in a dry powder form for optimizing muscle performance during exercise and for enhancing muscle cell repair and recovery following the cessation of exercise. The dry nutritional composition includes carbohydrates and proteins in a ratio in the range of 2.8 to 4.2 parts of the carbohydrates to 1.0 part of the proteins, wherein the carbohydrates are used for providing energy during exercise and the proteins are used for stimulating the release of insulin to the muscle cells during exercise and for repairing muscle cells after exercise. The dry nutritional composition further includes glutamine for reducing muscle stress by stimulating the immune system and for stimulating muscle cell recovery after exercise; arginine for stimulating the release of insulin within the muscle cells in order to facilitate the transport of glucose into the muscle cells during exercise and for the synthesis of glucose into glycogen; vitamin C for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise; and vitamin E for use as an anti-oxidant for preventing free radical formation during exercise and for protecting muscle cell integrity during exercise. Additionally, the dry nutritional composition also includes one or more electrolytes for replenishing electrolytes lost during exercise and for facilitating intestinal reabsorption of fluids, and for facilitating energy dependent processes; and an herbal compound being ciwujia for enhancing the immune system, reducing muscle stress, and decreasing heart rate during exercise.
摘要翻译：一种干粉形式的营养组合物，用于优化运动过程中的肌肉表现，并在运动停止后增强肌肉细胞的修复和恢复。干营养组合物包括碳水化合物和蛋白质的比例在2.8至4.2份碳水化合物的范围内至1.0份蛋白质，其中碳水化合物用于在运动期间提供能量，并且所述蛋白质用于刺激胰岛素的释放运动期间肌肉细胞和运动后肌肉细胞修复。干营养组合物还包括谷氨酰胺，用于通过刺激免疫系统和用于在运动后刺激肌肉细胞恢复来减少肌肉压力; 精氨酸用于刺激肌肉细胞内的胰岛素的释放，以便于在运动过程中将葡萄糖输送到肌肉细胞中并将葡萄糖合成为糖原; 维生素C用作抗氧化剂，用于在运动期间防止自由基形成并用于在运动期间保护肌肉细胞完整性; 和维生素E，用作抗氧化剂，用于防止运动期间的自由基形成，并用于在运动过程中保护肌肉细胞的完整性。此外，干营养组合物还包括一种或多种电解质，用于补充运动期间损失的电解质和促进流体的肠再吸收，并促进能量依赖性过程; 和一种草药化合物，用于增强免疫系统，减少肌肉压力，降低运动中的心率。

12. 发明申请

US20090137797A1 Organic Compounds 失效
标题翻译：有机化合物
公开(公告)号：US20090137797A1
公开(公告)日：2009-05-28
申请号：US12296969
申请日：2007-04-11
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： C07D223/12
CPC分类号： C07D223/12
摘要： A process for preparing compounds of formula (I) or a solvate or hydrate thereof, where R, R1, R2, R3 and R5 have the meanings as indicated in the specification. Such compounds are useful in the treatment of a number of conditions associated with substance P and neurokinin.
摘要翻译：制备式（I）化合物或其溶剂化物或水合物的方法，其中R，R 1，R 2，R 3和R 5具有说明书中所示的含义。这些化合物可用于治疗与P物质和神经激肽相关的许多病症。

13. 发明申请

US20070280997A1 Composition for enhancing muscle recovery 审中-公开
标题翻译：用于增强肌肉恢复的组合物
公开(公告)号：US20070280997A1
公开(公告)日：2007-12-06
申请号：US11444177
申请日：2006-05-31
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： A61K31/70
CPC分类号： A61K35/20 , A23L33/175 , A23L33/19 , A23V2002/00 , A61K31/70 , A61K31/7004 , A61K31/715 , A61K38/02 , A61K38/1709 , A61K2300/00 , A23V2200/316 , A23V2250/54252 , A23V2250/54246 , A23V2250/606 , A23V2250/0606 , A23V2250/0628 , A23V2250/61 , A23V2250/628 , A23V2250/5036 , A23V2250/5114
摘要： An essential composition that acts to prevent or retard loss of muscle strength and atrophy during extended periods of inactivity is provided. The compositions are characterized by a ratio of carbohydrate to protein of from about 1.5:1 to 2:1 and by the presence of a specific amino acid component of leucine and, optimally, argilline. The carbohydrate component is at least two members of a group of four sugars and the protein component is whey protein and casein. A preferred carbohydrate component is glucose and sucrose. The ratio of whey protein to casein in the subject compositions is about 3:1. The subject compositions are preferably provided in preparations containing conventional excipient materials such as flavors, coloring agents, emulsifiers, artificial sweeteners and the like, such preparations providing from about 33 to 58 grams of the essential composition, which comprises from about 15% to 80% by weight of said preparations.
摘要翻译：提供用于预防或延缓肌肉力量丧失并延长长时间不活动期间的萎缩的基本组成。组合物的特征在于碳水化合物与蛋白质的比例为约1.5:1至2:1，并且通过存在亮氨酸的特定氨基酸组分，最优选地是石质素。碳水化合物组分是四种糖的至少两种成员，蛋白质组分是乳清蛋白和酪蛋白。优选的碳水化合物组分是葡萄糖和蔗糖。本发明组合物中乳清蛋白与酪蛋白的比例为约3:1。主题组合物优选在含有常规赋形剂材料如调味剂，着色剂，乳化剂，人造甜味剂等的制剂中提供，所述制剂提供约33至58克的必需组合物，其包含约15％至80％的所述制剂。

14. 发明授权

US06989171B2 Sports drink composition for enhancing glucose uptake into the muscle and extending endurance during physical exercise 有权
标题翻译：运动饮料组合物，用于增强葡萄糖摄入肌肉，延长运动中的耐力
公开(公告)号：US06989171B2
公开(公告)日：2006-01-24
申请号：US10638908
申请日：2003-08-11
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： A23L2/66
CPC分类号： A23L2/52 , A23L2/39 , A23L33/15 , A23L33/16 , A23L33/17 , A23L33/175 , A23L33/185 , A23L33/19 , Y10S426/81
摘要： The present invention provides for a nutritional composition in a dry powder form or a liquid drink form for optimizing muscle performance during exercise. The dry nutritional composition includes carbohydrate and protein in a ratio, in the range of 2.8 to 4.2 parts of the carbohydrate to 1.0 part of the protein. One or more carbohydrates are sugars in the range of 50.51% to 84.81% by weight of the dry composition wherein the carbohydrates are a mixture of high and low glycemic sugars. One or more proteins are in the range of 10.29% to 32.25% by weight of the dry composition. The dry nutritional composition further includes a first vitamin being Vitamin C in the range of 0.06% to 1.78% of the dry composition for use as an antioxidant for preventing free radical formation during exercise and includes a second vitamin being Vitamin E in the range of 0.07% to 1.78% of the dry composition for use as an antioxidant for preventing free radical formation during exercise. The dry nutritional composition also includes electrolytes for replenishing electrolytes lost during exercise and for facilitating intestinal reabsorption of fluid.
摘要翻译：本发明提供了干粉形式或液体饮料形式的营养组合物，用于在运动过程中优化肌肉性能。干营养组合物包括碳水化合物和蛋白质，其比例为2.8至4.2份碳水化合物与1.0份蛋白质。一种或多种碳水化合物是干组合物重量的50.51％至84.81％范围内的糖，其中碳水化合物是高糖和低血糖的混合物。一种或多种蛋白质在干组合物的10.29％至32.25％的范围内。干营养组合物还包含维生素C的第一种维生素C在干组合物的0.06％至1.78％的范围内，用作用于防止运动过程中自由基形成的抗氧化剂，并且包括第二维生素维生素E的范围为0.07 用于防止运动过程中自由基形成的抗氧化剂的干组合物的％至1.78％。干营养组合物还包括用于补充运动期间损失的电解质的电解质和促进流体的肠再吸收。

15. 发明授权

US06716815B2 Nutritional intervention composition for enhancing and extending satiety 失效
标题翻译：营养干预组合物用于增强和延长饱腹感
公开(公告)号：US06716815B2
公开(公告)日：2004-04-06
申请号：US10211676
申请日：2002-08-02
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： A61K3816
CPC分类号： A23L33/21 , A23L33/12 , A23L33/18 , A23L33/185 , A23L33/19 , A23L33/40
摘要： This invention relates to a nutritional intervention composition in a dry power form for enhancing satiety prior to a meal and extending satiety after a meal in a calorically efficient fashion. The dry nutritional composition includes protein, caseinmacropeptides (CMP) or glycomacropeptides (GMP) or any hydrolysis product of GMP, long chain fatty acids, soluble and/or insoluble fibers. The dry nutritional composition includes protein in the range of 0.21% to 88.30%, glycomacropeptide in the range of 0.05% to 87.72%, oleic acid in the range of 2.27% to 97.25%, soluble fibers in the range of 0.19% to 79.05%, and insoluble fibers in the range of 0.19% to 79.05%. The composition may also include plant saponins, calcium and cholestyramine.
摘要翻译：本发明涉及一种用于在膳食之前增强饱腹感的干力形式的营养干预组合物，并且以高热量方式在饭后延长饱腹感。干营养组合物包括蛋白质，酪蛋白大分子肽（CMP）或糖巨肽（GMP）或GMP，长链脂肪酸，可溶性和/或不溶性纤维的任何水解产物。干营养组合物包括0.21％至88.30％范围内的蛋白质，0.05％至87.72％范围内的糖巨蛋白，2.27％至97.25％范围内的油酸，0.19％至79.05％的可溶性纤维，，不溶性纤维的含量为0.19％〜79.05％。组合物还可以包括植物皂苷，钙和考来烯胺。

16. 发明授权

US06558690B2 Nutritional composition for improving the efficacy of a lipase inhibitor 有权
公开(公告)号：US06558690B2
公开(公告)日：2003-05-06
申请号：US10017278
申请日：2001-12-14
申请人： Robert Portman
发明人： Robert Portman
IPC分类号： A61K4730
CPC分类号： A23L33/21 , A23L33/12 , A23L33/18 , A23L33/19 , A23L33/40 , A23V2002/00 , A23V2250/54246 , A23V2250/506 , A23V2250/5058 , A23V2250/188
摘要： A nutritional intervention composition is provided for enhancing the efficacy of an orally administered lipase inhibitor comprising a protein component of at least a glycomacropeptide or caseinmacropeptide, at least one C12-18 fatty acid comprising at least oleic acid and a fiber preferably comprising both soluble and insoluble fibers. The composition is administered concurrently with the lipase inhibitor to negate the action of the latter in inhibiting the release of cholecystokinin (CCK) which, in turn, reduces the feeling of satiety and stimulates appetite. These effects are all countered by the subject compositions which stimulate release of CCK and increase the level of bile in the intestine. These effects achieved by the subject nutritional intervention compositions, while not directly increasing the effectiveness of the lipase inhibitor, nonetheless enhance its efficacy.

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