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11. 发明申请

US20130197468A1 Device for Intramyocardial Delivery 审中-公开
标题翻译：心肌内输送装置
公开(公告)号：US20130197468A1
公开(公告)日：2013-08-01
申请号：US13751414
申请日：2013-01-28
申请人： David SCHWARTZMAN , Lee E. Weiss , Phil Gordon Campbell , Gary K. Fedder
发明人： David SCHWARTZMAN , Lee E. Weiss , Phil Gordon Campbell , Gary K. Fedder
IPC分类号： A61M5/00
CPC分类号： A61M5/00 , A61B5/0215 , A61B5/14503 , A61B5/14532 , A61B5/14539 , A61B17/068 , A61B2017/00004 , A61B2017/00022 , A61B2017/00243 , A61B2017/00893 , A61B2017/0648 , A61L27/3633 , A61L27/54
摘要： Methods and apparatuses for delivery of biologically active material and/or sensors to a target organ or system. The apparatuses allow for specific, controlled delivery of the biologically active material and targeted placement of sensors. The apparatuses may be fabricated from cellular and/or acellular biological active components to promote integration of sensors into tissue and achieve appropriate release of biologically active molecules. The apparatuses may be fabricated from plasma-containing materials or other biopolymers such that the apparatus will resorbed into the tissue following insertion. The biologically active cellular or acellular component may be incorporated into that material may then serve as the source of the therapeutic biologically active component. The apparatus may take the form of a screw, though numerous shapes arc contemplated. The delivery methods and apparatuses of the present invention may be employed in a wide variety of physiological and medical situations, with cardiac implementations being particularly appropriate.
摘要翻译：用于将生物活性物质和/或传感器递送至靶器官或系统的方法和装置。这些装置允许生物活性材料的特定的，受控的输送和传感器的目标放置。这些装置可以由细胞和/或细胞生物活性成分制成，以促进传感器集成到组织中并实现生物活性分子的适当释放。这些装置可以由含等离子体的材料或其他生物聚合物制成，使得装置在插入后将被吸收到组织中。可以将生物活性细胞或非细胞成分掺入，然后该物质可以用作治疗性生物活性成分的来源。该装置可以采用螺钉的形式，尽管预期了许多形状。本发明的递送方法和装置可以用于各种生理和医学情况，其中心脏实施是特别合适的。

12. 发明申请

US20120177694A1 Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom 有权
公开(公告)号：US20120177694A1
公开(公告)日：2012-07-12
申请号：US13177147
申请日：2011-07-06
申请人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
发明人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
IPC分类号： A61K9/00 , A61P29/00 , A61P31/00 , A61P35/00 , A61P17/00 , A61P5/00 , A61P37/02 , A61P37/06 , A61P27/02 , A61P11/00 , A61K35/16 , A61P9/00
CPC分类号： A61K35/16 , A61K38/18 , A61K38/19 , A61K38/22 , A61K38/37 , A61L27/3616 , A61L27/365 , A61L27/54
摘要： Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

13. 发明授权

US5079974A Sprayed metal dies 失效
标题翻译：喷涂金属模具
公开(公告)号：US5079974A
公开(公告)日：1992-01-14
申请号：US705321
申请日：1991-05-24
申请人： Lee E. Weiss , Lawrence L. Schultz
发明人： Lee E. Weiss , Lawrence L. Schultz
IPC分类号： B22F3/115 , B22F5/00 , B23P15/24
CPC分类号： B23P15/24 , B22F3/115 , B22F5/007 , B22F2998/10
摘要： A method for forming a sprayed metal die comprising the steps of first building a positive pattern of the die. Then, there is the step of spraying a first metal, having a first melting temperature, onto the pattern to form a first metal substrate. Next, there is the step of separating the pattern from the first metal substrate. Next, there is the step of spraying a second metal, having a second melting temperature higher than the first melting temperature, onto the first metal substrate to form a second metal substrate which bonds to the first metal substrate to resist shrinkage due to residual stress within the second metal substrate. Next, there is the step of heating the first and second substrates to a temperature higher than the first melting temperature, yet lower than the second melting temperature, to melt away the first metal substrate from the second metal substrate.
摘要翻译：一种用于形成喷涂的金属模具的方法，包括以下步骤：首先构建模具的正图案。然后，将具有第一熔融温度的第一金属喷涂到图案上以形成第一金属基板的步骤。接下来，存在将图案与第一金属基板分离的步骤。接下来，将具有高于第一熔融温度的第二熔融温度的第二金属喷涂到第一金属基板上以形成第二金属基板的步骤，该第二金属基板与第一金属基板结合，以抵抗由于第一金属基板内部的残余应力引起的收缩第二金属基板。接下来，存在将第一和第二基板加热至高于第一熔融温度但低于第二熔融温度的温度从第二金属基板熔化掉第一金属基板的步骤。

14. 发明授权

US4579380A Servo robot gripper 失效
标题翻译：伺服机器人夹具
公开(公告)号：US4579380A
公开(公告)日：1986-04-01
申请号：US558425
申请日：1983-12-06
申请人： Mark Zaremsky , Lee E. Weiss , Thomas A. Mutschler
发明人： Mark Zaremsky , Lee E. Weiss , Thomas A. Mutschler
IPC分类号： B25J13/08 , B25J15/04 , B25J19/02 , B25J15/08
CPC分类号： B25J13/082 , B25J15/0475 , B25J19/021 , Y10S294/907
摘要： A light weight servo controlled robot gripper is disclosed. A plastic body houses one or more threaded drive shafts which are powered by a direct current motor. Attached to the shafts are finger mounting blocks which support removable fingers and which can be driven both closer to and further away from a fixed point by the motor. Integral with at least one mounting block is a force transducer which monitors the load exerted on the finger through a pivot and lever action of a mounting bracket provided adjacent to the load cell. Since the transducer is in the block rather than the fingertip, fingers are readily interchangable without reinstrumentation. A limit switch, located above one of the finger mounting blocks, is used to determine coarse finger position, and an optical shaft encoder provides precise position information allowing the gripper to be utilized for a variety of position as well as force servoing tasks.
摘要翻译：公开了一种重量轻的伺服控制机器人夹持器。塑料体容纳由直流电动机驱动的一个或多个螺纹驱动轴。连接到轴上的是手指安装块，其支撑可移除的手指，并且可以通过马达被驱动到更靠近并远离固定点。与至少一个安装块成一体是力传感器，其通过邻近测力传感器设置的安装支架的枢轴和杠杆作用来监视施加在手指上的负载。由于换能器在块而不是指尖，手指易于互换而不进行重新装置。位于手指安装块上方的限位开关用于确定粗指位置，光轴编码器提供精确的位置信息，允许夹持器用于各种位置以及强制伺服任务。

15. 发明授权

US4472668A Multi-lead component manipulator 失效
标题翻译：多引线组件机械手
公开(公告)号：US4472668A
公开(公告)日：1984-09-18
申请号：US461799
申请日：1983-01-28
申请人： Thomas A. Mutschler , Arthur C. Sanderson , Lee E. Weiss
发明人： Thomas A. Mutschler , Arthur C. Sanderson , Lee E. Weiss
IPC分类号： B25J15/00 , B23P19/00 , B25J9/18 , B25J13/08 , B25J15/02 , B25J15/08 , G05B19/42
CPC分类号： B23P19/105 , B25J13/08 , B25J15/02 , Y10S294/907 , Y10T29/49131 , Y10T29/53183
摘要： A multi-lead component manipulator for the assembly of circuit boards has optical and tactile feedback systems and includes at least two and preferably three symmetric assemblies radially disposed about a component gripper assembly. Each symmetric assembly has a movable lead guide means for engaging a component lead and aligning the same for circuit board insertion. The guide means are adapted for independent arcuate and radial motion reflective of the optical feedback system and the gripper assembly is capable of axial movement for the acquisition and insertion of components. The tactile feedback system controls component insertion. The manipulator in an alternative embodiment has fixed guide means disposed above the movable guide means. The fixed guide means orient the component leads for acquisition by the movable guide means.
摘要翻译：用于组装电路板的多引线组件操纵器具有光学和触觉反馈系统，并且包括围绕组件夹持器组件径向设置的至少两个且优选三个对称组件。每个对称组件具有用于接合部件引线并将其对准以用于电路板插入的可移动引导引导装置。引导装置适于反射光学反馈系统的独立弧形和径向运动，并且夹持器组件能够轴向移动以用于部件的采集和插入。触觉反馈系统控制组件插入。在替代实施例中的操纵器具有设置在可移动引导装置上方的固定引导装置。固定导向装置使组件引线定向，以便由可移动引导装置进行采集。

16. 发明授权

US08529961B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom 有权
公开(公告)号：US08529961B2
公开(公告)日：2013-09-10
申请号：US13177147
申请日：2011-07-06
申请人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
发明人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
IPC分类号： A61K35/16
CPC分类号： A61K35/16 , A61K38/18 , A61K38/19 , A61K38/22 , A61K38/37 , A61L27/3616 , A61L27/365 , A61L27/54
摘要： Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

17. 发明授权

US08529960B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom 有权
公开(公告)号：US08529960B2
公开(公告)日：2013-09-10
申请号：US13177090
申请日：2011-07-06
申请人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
发明人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
IPC分类号： A61K35/16
CPC分类号： A61K35/16 , A61L27/3604 , A61L27/3616 , A61L27/3834 , A61L27/502 , A61L31/005 , A61L31/141
摘要： Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

18. 发明授权

US08529959B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom 有权
公开(公告)号：US08529959B2
公开(公告)日：2013-09-10
申请号：US13177061
申请日：2011-07-06
申请人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
发明人： Phil G. Campbell , James E. Burgess , Lee E. Weiss , Jason Smith
IPC分类号： A61K35/16
CPC分类号： A61K35/16 , A61K38/18 , A61K38/19 , A61K38/22 , A61K38/37 , A61L27/3616 , A61L27/365 , A61L27/54
摘要： Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

19. 发明授权

US5569272A Tissue-connective devices with micromechanical barbs 失效
标题翻译：具有微机械倒钩的组织连接装置
公开(公告)号：US5569272A
公开(公告)日：1996-10-29
申请号：US193385
申请日：1994-02-08
申请人： Michael L. Reed , Lee E. Weiss
发明人： Michael L. Reed , Lee E. Weiss
IPC分类号： A61F2/82 , A61M29/02 , A61M37/00 , F16B5/07 , H01L23/13 , H01L23/538 , H01L29/06 , A61B17/00
CPC分类号： A61F2/82 , A61M37/00 , F16B5/07 , H01L23/13 , H01L23/5385 , H01L29/0657 , A61F2/958 , A61F2002/8483 , A61F2220/0083 , A61M2037/0023 , A61M2037/003 , A61M25/104 , H01L2224/81899 , Y10T24/27
摘要： A system for linking a first member with a second member. The system is comprised of a first plurality of micromechanical barbs disposed on the first member. The system is also comprised of a second plurality of micromechanical barbs disposed on the second member. The barbs on the first member and the second member are of a shape such that a locking connection is formed between the first member and second member through the first plurality and second plurality of barbs when placed together. Each of the barbs of the first plurality and second plurality of barbs extend from the first member and second member, respectively, to a height no greater than 5 millimeters. The present invention also pertains to a micromechanical barb for linking with an object. The micrormechanical barb comprises a base. The micromechanical barb is also comprised of a support which extends from the base. The micromechanical barb additionally is comprised of a head which is disposed upon the support and which mates with the object such that a locking connection is found therebetween. The length of the support and the head is less than 5 millimeters.
摘要翻译：一种用于将第一构件与第二构件连接的系统。该系统由设置在第一构件上的第一多个微机械倒钩组成。该系统还包括设置在第二构件上的第二多个微机械倒钩。第一构件和第二构件上的倒钩具有这样的形状，使得当放置在一起时，通过第一多个和第二多个倒钩在第一构件和第二构件之间形成锁定连接。第一多个和第二多个倒钩中的每个倒钩分别从第一构件和第二构件延伸到不大于5毫米的高度。本发明还涉及用于与物体连接的微机械倒钩。微机械倒钩包括基座。微机械倒钩还包括从基部延伸的支撑件。微机械倒钩另外由头部组成，头部设置在支撑件上并与对象配合，从而在其间发现锁定连接。支架和头部的长度小于5毫米。

20. 发明授权

US5281789A Method and apparatus for depositing molten metal 失效
标题翻译：用于沉积熔融金属的方法和设备
公开(公告)号：US5281789A
公开(公告)日：1994-01-25
申请号：US919194
申请日：1992-07-24
申请人： Robert Merz , Fritz B. Prinz , Lee E. Weiss
发明人： Robert Merz , Fritz B. Prinz , Lee E. Weiss
IPC分类号： B22F3/115 , B23K9/04
CPC分类号： B23K9/04 , B22F3/115 , B22F2009/0848 , B22F2998/10 , Y10T29/49986
摘要： A collector electrode and adjacent electric weld torch are placed at a selected distance from a work surface or substrate. An electric welding current is generated so that a welding current arc forms between the collector electrode and the weld torch. A feed metal is then fed into the welding current arc and is melted into molten metal adjacent to the collector electrode. The molten metal is then deposited onto a work surface. The collector electrode and weld torch are positioned so that the welding current arc between the weld torch and the collector electrodes does not penetrate the work surface or the already-deposited metal.
摘要翻译：集电极和相邻的电焊炬放置在离工作表面或衬底一定距离处。产生电焊接电流，从而在集电极与焊炬之间形成焊接电弧。然后将进料金属进料到焊接电弧中，并熔化成与集电极相邻的熔融金属。然后将熔融金属沉积在工件表面上。集电极和焊炬的定位使得焊炬和集电极之间的焊接电流不会穿透工作表面或已经沉积的金属。

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