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    • 14. 发明申请
    • OSCILLATING HEAT TREATMENT METHOD FOR A SUPERALLOY
    • 用于超级合金的振荡热处理方法
    • US20100163142A1
    • 2010-07-01
    • US12226551
    • 2007-03-15
    • Michael OttRolf Wilkenhöner
    • Michael OttRolf Wilkenhöner
    • C22F1/10
    • C22C19/05C21D1/785C21D11/00C22C21/02C22F1/043C22F1/10F05B2230/40
    • Superalloy solidified in a directional manner often cannot be subjected to heat treatment because the heat treatment leads to recrystallization. As a result of the temperature profile during a heat treatment according to the invention which oscillates in the manner of a pendulum, a recrystallization during heat treatment can be avoided because mechanical stresses are reduced thanks to the recurring succession of dissolutions and precipitations of the precipitate. The method can be applied to a Ni-based superalloy with γ-precipitates. After the cyclic heat treatment, the temperature can be adjusted to and maintained at a temperature which is the same as or higher than the complete dissolution temperature. An oscillating movement can also take place above the complete dissolution temperature.
    • 由于热处理导致再结晶,所以以定向方式固化的高温合金经常不能进行热处理。 由于根据本发明的以摆锤的方式振荡的热处理期间的温度曲线的结果,可以避免热处理期间的再结晶,因为由于沉淀物的溶解和沉淀的反复循环而降低了机械应力。 该方法可应用于具有γ析出物的Ni基超级合金。 在循环热处理之后,可以将温度调整到并保持在与完全溶解温度相同或更高的温度。 振荡运动也可能发生在完全溶解温度之上。
    • 19. 发明授权
    • Use of Phyllanthus constituents for treating or preventing infections caused by hepatitis B-viruses
    • 使用叶绿素成分治疗或预防乙型肝炎病毒引起的感染
    • US07829124B2
    • 2010-11-09
    • US11563540
    • 2006-11-27
    • Michael OttMichael P. Manns
    • Michael OttMichael P. Manns
    • A61K36/00
    • A61K36/47Y02A50/387Y10S514/894A61K2300/00
    • The disclosure relates to a method of inhibiting synthesis of viral DNA in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting hepatitis B viral DNA synthesis in the mammal using the Phyllanthus component or substance. The disclosure also relates to a method of inhibiting viral gene expression in a mammal infected with a hepatitis B virus. This method includes administering at least one Phyllanthus component or substance to a mammal infected with the hepatitis B virus. It also includes inhibiting expression of at least one hepatitis B viral gene in the mammal using the Phyllanthus component or substance. These methods may form part of a method of preventing or treating hepatitis B infection.
    • 本公开涉及在感染乙型肝炎病毒的哺乳动物中抑制病毒DNA合成的方法。 该方法包括向感染乙型肝炎病毒的哺乳动物施用至少一种叶绿素成分或物质。 它还包括使用叶珠子成分或物质抑制哺乳动物中的乙型肝炎病毒DNA合成。 本公开还涉及在感染乙型肝炎病毒的哺乳动物中抑制病毒基因表达的方法。 该方法包括向感染乙型肝炎病毒的哺乳动物施用至少一种叶绿素成分或物质。 它还包括使用叶茶属成分或物质抑制哺乳动物中至少一种乙型肝炎病毒基因的表达。 这些方法可能形成预防或治疗乙型肝炎感染的方法的一部分。