专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

US20050060971A1 Safety cabinet for antibiohazard 有权
标题翻译：防腐柜安全柜
公开(公告)号：US20050060971A1
公开(公告)日：2005-03-24
申请号：US10981667
申请日：2004-11-05
申请人： Keiichi Ono
发明人： Keiichi Ono
IPC分类号： B08B15/02 , F24F3/16 , B01D50/00
CPC分类号： B01L1/04 , B01L2200/082 , B01L2300/0681 , B08B15/023 , B08B2215/003 , F24F3/1607 , Y10S55/18 , Y10S55/29 , Y10S55/46
摘要： A safety cabinet which can prevent contaminated air from leaking from a working space through the periphery of a front shutter, and which can prevent outside air from entering the working space has a peripheral structure part surrounding the working space formed with air suction ports in a part opposed to the inner surface of the front shutter connected to a negative pressure passage formed outside of the working space. The negative pressure passage guides air sucked through the air suction ports from the inside and the outside of the working space, toward a filter for purification of the air.
摘要翻译：一种能够防止被污染的空气通过前挡板的周边从工作空间泄漏并且可以防止外部空气进入工作空间的安全柜具有围绕由一部分中的空气吸入口形成的工作空间的周边结构部分与连接到形成在工作空间外部的负压通道的前快门的内表面相对。负压通道将从空气吸入口吸入的空气从工作空间的内部和外部引导到用于净化空气的过滤器。

12. 发明授权

US5342940A Polyethylene glycol derivatives, process for preparing the same 失效
标题翻译：聚乙二醇衍生物，其制备方法
公开(公告)号：US5342940A
公开(公告)日：1994-08-30
申请号：US119821
申请日：1993-09-13
申请人： Keiichi Ono , Yoshiyuki Kai , Hiroo Maeda
发明人： Keiichi Ono , Yoshiyuki Kai , Hiroo Maeda
IPC分类号： A61K38/00 , A61K47/48 , C07D251/26 , C07K1/107 , C08G65/32 , C08G65/329 , C08G65/333 , C12N9/96
CPC分类号： A61K47/48215 , C07D251/26 , C07K1/1077 , C08G65/32 , C08G65/329 , C08G65/333 , C12N9/96 , A61K38/00
摘要： High purity polyethylene glycol derivatives of formula (I) are useful as protein modifiers of interferons, t-PA, EGF, various hormones, etc. The thus modified protein has minimized antigenicity, prolonged plasma half life, or improved transfer to tissue. A novel process for preparing high purity polyethylene glycol derivatives is also disclosed.
摘要翻译：式（I）的高纯度聚乙二醇衍生物可用作干扰素，t-PA，EGF，各种激素等的蛋白质改性剂。由此修饰的蛋白质具有最小的抗原性，延长的血浆半衰期或改善的转移至组织。还公开了一种制备高纯度聚乙二醇衍生物的新方法。

13. 发明授权

US5093531A Polyethylene glycol substituted phenyl glyoxals 失效
标题翻译：聚乙二醇取代苯甲酸
公开(公告)号：US5093531A
公开(公告)日：1992-03-03
申请号：US347902
申请日：1989-05-05
申请人： Akihiko Sano , Hiroo Maeda , Yoshiyuki Kai , Keiichi Ono
发明人： Akihiko Sano , Hiroo Maeda , Yoshiyuki Kai , Keiichi Ono
IPC分类号： C12N9/00 , A61K38/00 , C07K1/02 , C07K1/06 , C07K1/107 , C07K1/113 , C07K7/23 , C07K14/00 , C07K14/52 , C07K14/53 , C07K14/535 , C07K14/575 , C07K14/58 , C07K14/60 , C07K14/65 , C08G65/32 , C08G65/323 , C08G65/329 , C08G65/334 , C08G65/48
CPC分类号： C08G65/323 , C07K1/064 , C07K1/1077 , C08G65/329 , C08G65/3346
摘要： A polyethylene glycol derivative of the formula ##STR1## wherein R represents a lower alkyl and n represents an optional positive integer which renders the average molecular weight of the polyethylene glycol moiety about 1,000 to 12,000, a peptide modified by said polyethylene glycol derivative and a method for production thereof.The polyethylene glycol derivative (I) is capable of modifying the guanidino groups in peptides. The peptides modified by the polyethylene glycol derivative (I) are extremely stable, are considerably delayed in biological clearance (i.e. the durability is extended) and exhibit their physiological activities effectively over the long period.

14. 发明授权

US4774319A Synthesis of a derivative of GRF and intermediate peptides 失效
标题翻译： GRF和中间体肽衍生物的合成
公开(公告)号：US4774319A
公开(公告)日：1988-09-27
申请号：US119279
申请日：1987-11-09
申请人： Keiichi Ono , Yoshiyuki Kai , Yoshiaki Takebayashi , Akihiko Sano , Kazushi Suwa
发明人： Keiichi Ono , Yoshiyuki Kai , Yoshiaki Takebayashi , Akihiko Sano , Kazushi Suwa
IPC分类号： A61K38/00 , C07K14/60 , C07K7/06 , C07K7/08 , C07K7/10
CPC分类号： C07K14/60 , A61K38/00 , Y02P20/55 , Y10S930/12
摘要： A process for the manufacture of a polypeptide (I) having the formula: ##STR1## which comprises steps of: (a) coupling, successively and in the order of the sequence of the polypeptide (I), the four protected fragments A, B, C and D or five protected fragments A, B, C, E and F,said fragment A by the formula, Leu-Gin-Asp-Ile-Met-Ser-Arg-NH.sub.2said fragment B by the formula, Gln-Leu-Ser-Ala-Arg-Lys-Leusaid fragment C by the formula, Arg-Lys-Val-Leu-Glysaid fragment D by the formula, Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyrsaid fragment E by the formula, Ile-Phe-Thr-Asn-Ser-Tyrand said fragment F by the formula, Tyr-Ala-Asp-Ala being represented, respectively, and(b) eliminating, at the end of sequence, all the protecting groups to provide the polypeptide (I) which is active on the stimulation of the release of the growth hormone and thus is very useful as medicine for treatment of growth hormone deficiency disease and the like.
摘要翻译：一种制备具有下式的多肽（I）的方法：其包括以下步骤：（a）依次和按照多肽（I ），四个保护的片段A，B，C和D或五个保护的片段A，B，C，E和F，所述片段A通过式Leu-Gin-Asp-Ile-Met-Ser-Arg-NH2表示片段B由式Gln-Leu-Ser-Ala-Arg-Lys-Leu表示，由式Arg-Lys-Val-Leu-Gly表示的片段C表示下式的Tyr-Ala-Asp-Ala- Ile-Phe-Thr-Asn-Ser-Tyr分别表示分子式为Ile-Phe-Thr-Asn-Ser-Tyr的片段E和由式Tyr-Ala-Asp-Ala表示的所述片段F，以及（b）在序列结束时，除去所有保护基以提供在刺激生长激素释放方面具有活性的多肽（I），因此作为治疗生长激素缺乏症的药物非常有用，类似。

15. 发明授权

US4400393A Novel bicyclooctane compounds 失效
标题翻译：新型双环辛烷化合物
公开(公告)号：US4400393A
公开(公告)日：1983-08-23
申请号：US246938
申请日：1981-03-24
申请人： Shunsuke Sami , Akihiko Sugie , Keiichi Ono , Hajime Kawakami , Atsuyuki Kojima , Junki Katsube
发明人： Shunsuke Sami , Akihiko Sugie , Keiichi Ono , Hajime Kawakami , Atsuyuki Kojima , Junki Katsube
IPC分类号： C07C69/013 , A61K31/19 , A61K31/215 , A61P9/00 , A61P9/10 , C07C45/59 , C07C45/71 , C07C49/743 , C07C51/00 , C07C59/46 , C07C59/62 , C07C59/66 , C07C67/00 , C07C405/00 , C07D317/72 , C07F9/40 , C07C69/753
CPC分类号： C07F9/4018 , C07C405/0083 , C07C45/59 , C07C45/71 , C07C49/743 , C07C59/46 , C07C59/66 , C07D317/72 , Y02P20/55
摘要： A novel bicyclooctane derivative represented by the formula: ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 alkyl, X is ethylene or vinylene, and Y.sub.1 and Y.sub.2 are independently hydrogen or a hydroxyl-protecting group, or a pharmaceutically acceptable salt of said compound in which R.sub.1 is hydrogen. Said compound and pharmaceutically acceptable salt are chemically stable, have platelet anti-aggregation activity without undesirable pharmacological actions and exhibit the duration of high biological activity.
摘要翻译：由下式表示的新型双环辛烷衍生物：其中R 1是氢或C 1-4烷基，X是亚乙基或亚乙烯基，Y 1和Y 2独立地是氢或羟基保护基，或所说化合物的药学上可接受的盐其中R1是氢。所述化合物和药学上可接受的盐是化学稳定的，具有没有不希望的药理作用的血小板抗聚集活性，并表现出高生物活性的持续时间。

16. 发明授权

US4039670A Butyrophenone compounds as psychotropics 失效
标题翻译：丁基酮化合物作为PSYCHOTROPICS
公开(公告)号：US4039670A
公开(公告)日：1977-08-02
申请号：US568819
申请日：1975-04-17
申请人： Kikuo Sasajima , Keiichi Ono , Masaru Nakao , Hisao Yamamoto
发明人： Kikuo Sasajima , Keiichi Ono , Masaru Nakao , Hisao Yamamoto
IPC分类号： C07D295/10 , A61K31/435 , A61K31/443 , A61K31/445 , A61K31/451 , A61P9/12 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/20 , A61P29/00 , C07D211/14 , C07D211/52 , C07D405/06 , C07D471/10 , C07D487/10 , A01N9/22
CPC分类号： C07D211/52
摘要： Butyrophenone compounds having excellent psychotropic activities represented by the formula: ##STR1## wherein R.sup.1 is a halogen atom, R.sup.2 is a lower alkyl group, and Z is a group of either one of the formulae: ##STR2## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.3 is a hydrogen atom or a hydroxyl group but only when said additional single bond linkage is not present and R.sup.4 is a hydrogen atom or a phenyl or benzyl group optionally substituted with one or two substituents selected from the group consisting of halogen, lower alkyl, lower alkyoxy and trifluoromethyl on the benzene ring (except monohalophenyl)), ##STR3## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.5 is a hydrogen atom or a lower alkyl group and R.sup.6 and R.sup.7 are each a hydrogen atom, a halogen atom or a lower alkyl group), ##STR4## (wherein R.sup.8 is a hydrogen atom or a lower alkyl group and R.sup.9 is a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group), ##STR5## (wherein R.sup.10 is a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group), or ##STR6##
摘要翻译：其中R1为卤原子，R2为低级烷基，Z为下列任何一个基团的基团：其中虚线表示的具有极好的精神活性的丁基苯酚化合物由下式表示：线表示任选地存在另外的单键键，R3是氢原子或羟基，但仅在所述另外的单键键不存在且R4是氢原子或任选被一个或两个取代基取代的苯基或苄基时取代基选自苯环上的卤素，低级烷基，低级烷氧基和三氟甲基（单卤代苯基除外）），其中虚线表示任选地存在另外的单键键，R5是氢原子或低级烷基，R6和R7各自为氢原子，卤素原子或低级烷基），其中R8为氢原子或低级烷基，R9为氢原子，卤素原子，低级烷基或低级烷氧基），其中R 10为氢原子，卤素原子，低级烷基，低级烷氧基或三氟甲基。（5）

17. 发明授权

US4012514A Aryl ketones and production thereof 失效
标题翻译：芳基酮及其制备
公开(公告)号：US4012514A
公开(公告)日：1977-03-15
申请号：US600118
申请日：1975-07-29
申请人： Junki Katsube , Masaru Nakao , Kikuo Sasajima , Isamu Maruyama , Masaharu Takayama , Keiichi Ono , Shigenari Katayama , Yoshihiro Tanaka , Shigeho Inaba , Hisao Yamamoto
发明人： Junki Katsube , Masaru Nakao , Kikuo Sasajima , Isamu Maruyama , Masaharu Takayama , Keiichi Ono , Shigenari Katayama , Yoshihiro Tanaka , Shigeho Inaba , Hisao Yamamoto
IPC分类号： C07D211/52 , C07D295/084 , C07D295/104 , C07D295/108 , C07D233/32
CPC分类号： C07D295/108 , C07D211/52 , C07D295/092 , C07D295/104
摘要： Novel olefinic aryl ketone compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, halogen, C.sub.1-4 alkyl, or C.sub.1-4 alkoxy, R.sup.2 is hydrogen or halogen, and X is a group of the formula: ##STR2## and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reaction of an acetylenic alcohol of the formula: ##STR3##wherein R.sup.1 and R.sup.2 are each as defined above with formaldehyde and an piperidine compound of the formula: , or its non-toxic salt; reduction of the resultant acetylenic aryl alcohol; and oxidation of the resultant olefinic aryl alcohol.
摘要翻译：新颖的下式的烯属芳基酮化合物：其中R 1是氢，卤素，C 1-4烷基或C 1-4烷氧基，R 2是氢或卤素，X是下式的基团： IMAGE>及其无毒盐，其具有各种有用的药理活性，并且可以通过下式的炔属醇与下式结合产生：其中R 1和R 2各自如上所定义，其中R 1和R 2各自为甲醛，式：或，或其无毒盐; 所得炔属芳基醇的还原; 和所得烯属芳基醇的氧化。

18. 发明授权

US07323026B2 Safety cabinet for antibiohazard 有权
标题翻译：防腐柜安全柜
公开(公告)号：US07323026B2
公开(公告)日：2008-01-29
申请号：US11362848
申请日：2006-02-28
申请人： Keiichi Ono
发明人： Keiichi Ono
IPC分类号： B01D50/00
CPC分类号： B01L1/04 , B01L2200/082 , B01L2300/0681 , B08B15/023 , B08B2215/003 , F24F3/1607 , Y10S55/18 , Y10S55/29 , Y10S55/46
摘要： A safety cabinet which can prevent contaminated air from leaking from a working space through the periphery of a front shutter, and which can prevent outside air from entering the working space has a peripheral structure part surrounding the working space formed with air suction ports in a part opposed to the inner surface of the front shutter connected to a negative pressure passage formed outside of the working space. The negative pressure passage guides air sucked through the air suction ports from the inside and the outside of the working space, toward a filter for purification of the air.
摘要翻译：一种能够防止被污染的空气通过前挡板的周边从工作空间泄漏并且可以防止外部空气进入工作空间的安全柜具有围绕由一部分中的空气吸入口形成的工作空间的周边结构部分与连接到形成在工作空间外部的负压通道的前快门的内表面相对。负压通道将从空气吸入口吸入的空气从工作空间的内部和外部引导到用于净化空气的过滤器。

19. 发明授权

US06755734B2 Fan filter unit control system and clean room provided with same 失效
标题翻译：风扇过滤器单元控制系统和洁净室提供同样的
公开(公告)号：US06755734B2
公开(公告)日：2004-06-29
申请号：US10267449
申请日：2002-10-08
申请人： Makoto Yokoyama , Keiichi Ono , Fumiyuki Tamura
发明人： Makoto Yokoyama , Keiichi Ono , Fumiyuki Tamura
IPC分类号： B01L104
CPC分类号： F24F3/161 , F24F11/39 , F24F11/77 , F24F11/79 , H01L21/67017 , H01L21/67253
摘要： Information from fan filter units and differential pressure gauges provided in a ceiling of a clean room is used to control directions and volumes of air flows blown from respective fan filter units. In order to improve a wind velocity distribution in the clean room, pressure in a ceiling chamber is made uniform and control of the FFU revolution speeds of fan filter units is made easy. In order to control directions of air flows in the clean room, damper adjusting mechanisms are provided under a grating floor of the clean room. Such arrangement enables optimizing an operating condition of the clean room and achieving energy saving.
摘要翻译：用于设置在洁净室的天花板上的风扇过滤器单元和差压计的信息用于控制从各个风扇过滤器单元吹送的空气流的方向和体积。为了提高洁净室内的风速分布，使天花板室内的压力均匀，并且容易控制风扇过滤器单元的FFU转速。为了控制洁净室中的空气流动方向，在洁净室的格栅地板下设置阻尼器调节机构。这样的布置使得能够优化洁净室的运行状态并实现节能。

20. 发明授权

US5459093A Method for forming dummy pattern in a semiconductor device 失效
标题翻译：在半导体器件中形成虚拟图案的方法
公开(公告)号：US5459093A
公开(公告)日：1995-10-17
申请号：US214141
申请日：1994-03-17
申请人： Hideaki Kuroda , Keiichi Ono
发明人： Hideaki Kuroda , Keiichi Ono
IPC分类号： H01L21/3205 , G06F17/50 , H01L21/82 , H01L23/52 , H01L27/02 , H01L21/70 , H01L27/00
CPC分类号： H01L27/0207 , Y10S438/926
摘要： Method of forming a dummy pattern without inducing crosstalk between conductive interconnects which would normally be caused by increase in capacitance between the interconnects. Also, absolute steps of devices are made uniform. Furthermore, the flatness of devices is improved. In a device having a multilayer aluminum metallization structure, let Chip be data about a region on which a dummy pattern should be defined. Let I.sub.Mi be data about a region occupied by an aluminum interconnect pattern on the ith layer. Let I.sub.Di be data about a dummy pattern on the ith layer, or data sought for. Let (Chip-I.sub.Mi).sub.D be data about the dummy pattern region obtained by decrement of data. The data (Chip-I.sub.Mi).sub.D about the dummy pattern region is ANDed with data I.sub.M(i+1) about the conduction pattern on the (i+1)th layer or with data I.sub.D(i+1) about the dummy pattern. Thus, data I.sub.Di about the dummy pattern is created. The dummy pattern on the ith layer is created, based on the created data I.sub.Di.
摘要翻译：形成虚设图案的方法，而不会引起通常由互连之间的电容增加引起的导电互连之间的串扰。此外，设备的绝对步骤均匀。此外，设备的平坦度得到改善。在具有多层铝金属化结构的器件中，令芯片是关于其上应限定虚拟图案的区域的数据。使IMi是关于第i层上的铝互连图案所占据的区域的数据。让IDi是关于第i层上的虚拟模式或寻求的数据的数据。令（Chip-IMi）D是通过数据递减获得的虚拟图形区域的数据。关于虚拟图案区域的数据（Chip-IMi）D与关于第（i + 1）层上的导电图案的数据IM（i + 1）或关于虚拟图案的数据ID（i + 1）进行AND。因此，创建关于虚拟图案的数据IDi。基于创建的数据IDi创建第i层上的虚拟模式。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式