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11. 发明授权

US08436038B2 Indole and indazole compounds as an inhibitor of cellular necrosis 有权
公开(公告)号：US08436038B2
公开(公告)日：2013-05-07
申请号：US12671038
申请日：2008-08-18
申请人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
发明人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
IPC分类号： A01N43/38 , A61K31/405
CPC分类号： C07D417/06 , A61K31/404 , A61K31/416 , A61K31/427 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/541 , A61K31/675 , A61K45/06 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D487/04 , C07F9/65583 , C07F9/65586
摘要： The present invention relates to indole or indazole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole or indazole compounds as an active ingredient.

12. 发明授权

US08309586B2 Glucokinase activators and pharmaceutical compositions containing the same as an active ingredient 有权
标题翻译：葡糖激酶活化剂和含有其作为活性成分的药物组合物
公开(公告)号：US08309586B2
公开(公告)日：2012-11-13
申请号：US13329831
申请日：2011-12-19
申请人： Soon Ha Kim , Sung Bae Lee , Seung Hyun Yoon , Mi Kyoung Cho , Kyoung Hee Kim , Heui Sul Park , Hyoung Jin Kim
发明人： Soon Ha Kim , Sung Bae Lee , Seung Hyun Yoon , Mi Kyoung Cho , Kyoung Hee Kim , Heui Sul Park , Hyoung Jin Kim
IPC分类号： A61K31/427 , C07D417/04
CPC分类号： C07D417/14 , C07D417/04 , C07D487/04
摘要： Disclosed are new compounds of formula (1) exhibiting excellent activity for glucokinase, pharmaceutical compositions having the same as an active ingredient, and a method of using the same as an active ingredient for lowering blood glucose level: in which the substituents are as defined herein.
摘要翻译：公开了对葡糖激酶具有优异活性的新的式（1）化合物，与活性成分相同的药物组合物及其用作降低血糖水平的活性成分的方法：其中取代基如本文所定义。

13. 发明申请

US20120252798A1 INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS 有权
标题翻译：作为细胞坏死因子抑制剂的化合物
公开(公告)号：US20120252798A1
公开(公告)日：2012-10-04
申请号：US13493045
申请日：2012-06-11
申请人： Soon Ha KIM , Hyoung Jin Kim , Sun Young Koo , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Seung Yup Paek , Hyo Shin Kwak , Dong Ook Seo , Eok Park
发明人： Soon Ha KIM , Hyoung Jin Kim , Sun Young Koo , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Seung Yup Paek , Hyo Shin Kwak , Dong Ook Seo , Eok Park
IPC分类号： A61K31/427 , A61K31/4439 , A61K31/422 , A61K31/4245 , A61K31/5377 , A61K31/496 , A61K31/541 , A61K31/4985 , A61P1/16 , A61P25/28 , A61P9/10 , A61P3/10 , A61P1/18 , A61P31/04 , A61P31/12 , A61P37/00 , A61P19/02 , A61P13/12 , A61P35/02 , A61P35/00 , A61P25/00 , A61P17/06 , A61P29/00 , A61P13/00 , A61P17/02 , A61P17/16 , A61P25/16 , A61P31/00 , A61P3/04 , A61P7/02 , A61P9/12 , A61P3/00 , A61P37/06 , A61K31/454
CPC分类号： C07D417/06 , A61K31/404 , A61K31/416 , A61K31/427 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/541 , A61K31/675 , A61K45/06 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D487/04 , C07F9/65583 , C07F9/65586
摘要： The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.
摘要翻译：本发明涉及可用于预防或治疗细胞坏死和坏死相关疾病的新的吲哚化合物，其药学上可接受的盐或异构体。本发明还涉及用于预防或治疗细胞坏死和坏死相关疾病的方法和组合物，其包含所述吲哚化合物作为活性成分。

14. 发明授权

US07508768B2 Traffic measurement system and traffic analysis method thereof 有权
标题翻译：交通测量系统及其交通分析方法
公开(公告)号：US07508768B2
公开(公告)日：2009-03-24
申请号：US10693416
申请日：2003-10-23
申请人： Seung Hyun Yoon , Tae Soo Jeong , Tae Sang Choi , Hyung Hwan Kim , Hyung Seok Chung , Jeong Sook Park , Chang Hoon Kim
发明人： Seung Hyun Yoon , Tae Soo Jeong , Tae Sang Choi , Hyung Hwan Kim , Hyung Seok Chung , Jeong Sook Park , Chang Hoon Kim
IPC分类号： H04L12/26 , H04J1/16 , G06F13/00
CPC分类号： H04L43/026 , H04L43/045 , H04L43/062
摘要： A traffic measurement system and a traffic analysis method are provided. The traffic measurement system includes a plurality of measurement devices that collect all of packets flowing through Internet links, extract traffic data required to analyze traffic from the collected packets, and process the extracted data into predetermined flow types, and an analysis server that identifies applications of traffic by analyzing the traffic data transferred from the plurality of measurement devices as a whole, classifies the identified applications into predetermined traffic types, and outputs the classification result. The traffic measurement system measures the traffics in the Internet network and processes the measured traffics to generate detailed traffic statistical data according to applications. In particular, the traffics are analyzed considering measurement data from various points, and the data for identifying the applications are extracted from headers of the applications included in payloads of IP packets in real time. Accordingly, detailed traffic analysis result is provided.
摘要翻译：提供了交通量测系统和交通分析方法。交通测量系统包括多个测量装置，其收集通过互联网链路流动的所有分组，提取从所收集的分组中分析流量所需的业务数据，并将所提取的数据处理为预定的流类型;以及分析服务器，通过分析从多个测量设备传送的业务数据作为整体，将所识别的应用分类为预定的业务类型，并输出分类结果。流量测量系统测量互联网网络中的流量，并根据应用程序处理测量的流量以生成详细的流量统计数据。特别地，考虑来自各个点的测量数据来分析流量，并且实时地从包含在IP分组的有效载荷中的应用的头部中提取用于识别应用的数据。因此，提供了详细的交通分析结果。

15. 发明授权

US08595568B2 Integration agent device for node including multi-layered equipment and fault management method thereof 有权
标题翻译：包含多层设备的节点集成代理设备及其故障管理方法
公开(公告)号：US08595568B2
公开(公告)日：2013-11-26
申请号：US12543590
申请日：2009-08-19
申请人： Seung Hyun Yoon , You Hyeon Jeong , Hyung Seok Chung
发明人： Seung Hyun Yoon , You Hyeon Jeong , Hyung Seok Chung
IPC分类号： G06F11/00
CPC分类号： H04L41/0622 , H04L12/00 , H04L41/00 , H04L41/0206 , H04L41/044 , H04L43/00 , H04L69/40
摘要： An integration agent device and its fault management method for a node including multi-layered devices are disclosed to effectively control a node including two or more communication devices of different layers and integrally processing relevant fault information. The integration agent device includes: one or more control and management modules controlling and managing one or more communications network devices by layer; and an inter-layer interworking processing module integrating and processing information of the communications network devices by using inter-layer interworking information, and notifying a management system accordingly, wherein the information of the communications network devices is transmitted through the one or more control and management.
摘要翻译：公开了一种用于包括多层设备的节点的集成代理设备及其故障管理方法，以有效地控制包括不同层的两个或多个通信设备的节点并且整体地处理相关的故障信息。集成代理设备包括：一个或多个控制和管理模块，按层控制和管理一个或多个通信网络设备; 以及层间互通处理模块，通过使用层间互通信息来对通信网络设备的信息进行集成处理，并相应地通知管理系统，其中通过所述一个或多个控制和管理来传送所述通信网络设备的信息。

16. 发明申请

US20100210647A1 INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS 有权
标题翻译：作为细胞坏死因子抑制剂的化合物
公开(公告)号：US20100210647A1
公开(公告)日：2010-08-19
申请号：US12671180
申请日：2008-08-18
申请人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Seung Yup Paek , Hyo Shin Kwak , Dong Ook Seo , Eok Park
发明人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Seung Yup Paek , Hyo Shin Kwak , Dong Ook Seo , Eok Park
IPC分类号： A61K31/427 , C07D417/04 , C07D413/04 , C07D417/14 , A61K31/5377 , A61K31/496 , A61K31/422 , A61P25/00 , A61P17/00 , A61P25/16 , A61P9/10
CPC分类号： C07D417/06 , A61K31/404 , A61K31/416 , A61K31/427 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/541 , A61K31/675 , A61K45/06 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D487/04 , C07F9/65583 , C07F9/65586
摘要： The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.
摘要翻译：本发明涉及可用于预防或治疗细胞坏死和坏死相关疾病的新的吲哚化合物，其药学上可接受的盐或异构体。本发明还涉及用于预防或治疗细胞坏死和坏死相关疾病的方法和组合物，其包含所述吲哚化合物作为活性成分。

17. 发明申请

US20100197673A1 INDOLE AND INDAZOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS 有权
标题翻译：作为细胞坏死因子抑制剂的吲哚和吲哚类化合物
公开(公告)号：US20100197673A1
公开(公告)日：2010-08-05
申请号：US12671038
申请日：2008-08-18
申请人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
发明人： Soon Ha Kim , Hyoung Jin Kim , Sun Young Koo , Chul Woong Chung , Sung Bae Lee , Heui Sul Park , Seung Hyun Yoon , Hyo Shin Kwak , Dong Ook Seo , Eok Park
IPC分类号： A61K31/541 , C07D401/02 , A61K31/4439 , C07D209/04 , A61K31/404 , A61K31/497 , C07D417/14 , C07D403/02 , A61K31/496 , C07D413/02 , A61K31/5377 , A61K31/454 , C07D231/56 , A61K31/416 , A61P1/16 , A61P25/00 , A61P3/10 , A61P31/00 , A61P19/02 , A61P35/00 , A61P35/02 , A61P11/00 , A61P17/00
CPC分类号： C07D417/06 , A61K31/404 , A61K31/416 , A61K31/427 , A61K31/4439 , A61K31/445 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/541 , A61K31/675 , A61K45/06 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D487/04 , C07F9/65583 , C07F9/65586
摘要： The present invention relates to indole or indazole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole or indazole compounds as an active ingredient.
摘要翻译：本发明涉及可用于预防或治疗细胞坏死和坏死相关疾病的吲哚或吲唑化合物，其药学上可接受的盐或异构体。本发明还涉及用于预防或治疗细胞坏死和坏死相关疾病的方法和组合物，其包含所述吲哚或吲唑化合物作为活性成分。

18. 发明授权

US07715317B2 Flow generation method for internet traffic measurement 有权
标题翻译：互联网流量测量流量生成方法
公开(公告)号：US07715317B2
公开(公告)日：2010-05-11
申请号：US10933930
申请日：2004-09-02
申请人： Jeong Sook Park , Seung Hyun Yoon , Hyung Hwan Kim , Chang Hoon Kim , Hyung Seok Chung , Byung Joon Lee , Taesang Choi , Tae Soo Chung
发明人： Jeong Sook Park , Seung Hyun Yoon , Hyung Hwan Kim , Chang Hoon Kim , Hyung Seok Chung , Byung Joon Lee , Taesang Choi , Tae Soo Chung
IPC分类号： H04L12/26
CPC分类号： H04L43/026
摘要： Provided is a flow generation method for Internet traffic measurement. In the flow generation method, dependency between packet collecting time and flow generating time is removed using a virtual timer and a flow generation completion processing interval is controlled to skip by a unit time in response to a user's request. Also, a fragmented packet processing method is selectively used at need and a FIN timeout is applied selectively to a timeout mechanism used in flow generation completion. Thereby, this invention can improve accuracy and efficiency of Internet traffic measurement.
摘要翻译：提供了一种用于互联网流量测量的流生成方法。在流生成方法中，使用虚拟定时器去除分组收集时间和流生成时间之间的依赖关系，并且响应于用户的请求，控制流生成完成处理间隔以单位时间跳过。此外，根据需要选择性地使用分段分组处理方法，并且选择性地对用于流生成完成的超时机制应用FIN超时。因此，本发明可以提高互联网流量测量的准确性和效率。

19. 发明申请

US20080112549A1 METHOD AND SYSTEM FOR PROCESSING BILLING OF INCLUDING QOS INFORMATION 审中-公开
标题翻译：包括QOS信息处理结算的方法和系统
公开(公告)号：US20080112549A1
公开(公告)日：2008-05-15
申请号：US11940776
申请日：2007-11-15
申请人： Seung Hyun Yoon , You Hyeon Jeong , Byung Joon Lee , Hyung Seok Chung
发明人： Seung Hyun Yoon , You Hyeon Jeong , Byung Joon Lee , Hyung Seok Chung
IPC分类号： H04M15/10
CPC分类号： H04M15/00 , H04L12/14 , H04L12/1485 , H04M15/10 , H04M15/80 , H04M15/8016 , H04M2215/74 , H04M2215/7414
摘要： A method and system for processing billing of including QoS information are provided. In the method, a call is initiated by transmitting/receiving packets directly to/from an opponent terminal after signaling with the opponent terminal using a session initiation protocol through the signaling server. Then, QoS of the call is measured while communicating with the opponent terminal. A billing process is performed of including the QoS measuring result by transmitting the QoS measuring result to the signaling server after the call established to the opponent terminal is terminated.
摘要翻译：提供了一种用于处理包括QoS信息的计费的方法和系统。在该方法中，通过使用通过信令服务器的会话发起协议与对手终端进行信令之后，直接向对手终端发送/接收分组，从而发起呼叫。然后，在与对方终端通信时测量呼叫的QoS。在终止对方终端的呼叫之后，通过将QoS测量结果发送给信令服务器来执行包括QoS测量结果的计费处理。

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