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11. 发明授权

US07893401B2 Mass spectrometer using a dynamic pressure ion source 有权
标题翻译：质谱仪使用动态离子源
公开(公告)号：US07893401B2
公开(公告)日：2011-02-22
申请号：US12158458
申请日：2006-12-20
申请人： Li Ding
发明人： Li Ding
IPC分类号： H01J49/04
CPC分类号： H01J49/062 , H01J49/0481 , H01J49/164
摘要： A mass spectrometer has a pulsed ion source, a first ion trap (10) for trapping ions generated by the pulsed ion source and for locating trapped ions for subsequent ejection from the first ion trap. A pulse of cooling gas is introduced into the first ion trap (10) at a peak pressure suitable for enabling the first ion trap (10) to trap ions. A turbomolecular pump (17) reduces the pressure of cooling gas before the trapped ions are ejected from the first ion trap (1) towards a second ion trap (20) for analysis. The pulsed ion source has a sample plate (14) which forms an end wall of the first ion trap (10).
摘要翻译：质谱仪具有脉冲离子源，第一离子阱（10），用于捕获由脉冲离子源产生的离子，并用于定位捕获的离子用于随后从第一离子阱排出。将冷却气体的脉冲以适于使第一离子阱（10）捕获离子的峰值压力引入到第一离子阱（10）中。涡轮分子泵（17）在被捕获的离子从第一离子阱（1）向第二离子阱（20）排出之前降低冷却气体的压力，用于分析。脉冲离子源具有形成第一离子阱（10）的端壁的样品板（14）。

12. 发明授权

US07789910B2 Optical material and method for modifying the refractive index 有权
$Optical material and method for modifying the refractive index$
标题翻译：用于改变折射率的光学材料和方法
公开(公告)号：US07789910B2
公开(公告)日：2010-09-07
申请号：US11948298
申请日：2007-11-30
申请人： Wayne H. Knox , Li Ding , Jay F. Kunzler , Dharmendra Jani , Candido D. Pinto
发明人： Wayne H. Knox , Li Ding , Jay F. Kunzler , Dharmendra Jani , Candido D. Pinto
IPC分类号： A61F2/16
CPC分类号： A61F2/1613 , A61B18/20 , A61F2/14 , A61F2/16 , A61F2/1627 , A61F2/1635 , B29D11/00461 , B29D11/023 , C08J7/12 , C08J7/123 , G02C2202/14
摘要： A method for modifying the refractive index of an optical, polymeric material. The method comprises irradiating select regions of the optical, polymeric material with a focused, visible or near-IR laser having a pulse energy from 0.05 nJ to 1000 nJ. The irradiation results in the formation of refractive optical structures, characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material. The method can be used to modify the refractive index of an intraocular lens following the surgical implantation of the intraocular lens in a human eye. The invention is also directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material.
摘要翻译：用于改变光学聚合物材料的折射率的方法。该方法包括用具有0.05nJ至1000nJ的脉冲能量的聚焦，可见或近红外激光照射光学聚合物材料的选择区域。照射导致折射光学结构的形成，其特征在于折射率的变化，显示很少或没有散射损失，并且在拉曼光谱方面相对于未照射的光学聚合物材料没有显着差异。该方法可以用于在人眼中手术植入人工晶状体后修改眼内透镜的折射率。本发明还涉及一种包括折射光学结构的光学器件，其中折射结构的特征在于折射率的变化，表现出很少的或没有散射损耗，并且在拉曼光谱方面相对于未辐照的表现没有显着的差异光学，聚合材料。

13. 发明申请

US20100005429A1 INTEGRATED SINGLE SPICE DECK SENSITIZATION FOR GATE LEVEL TOOLS 有权
标题翻译：针对门级水平工具的集成单个单位敏感度
公开(公告)号：US20100005429A1
公开(公告)日：2010-01-07
申请号：US12166630
申请日：2008-07-02
申请人： Jindrich Zejda , Narender Hanchate , Rupesh Nayak , Li Ding
发明人： Jindrich Zejda , Narender Hanchate , Rupesh Nayak , Li Ding
IPC分类号： G06F17/50
CPC分类号： G06F17/5036 , G06F17/505
摘要： One embodiment of the present invention provides systems and techniques for generating a transistor-level description of a subcircuit. A user may want to simulate a subcircuit in a circuit using a transistor-level simulator, and one or more cells in the subcircuit may need to be sensitized so that the cells are in a desired state when the subcircuit is simulated. An embodiment modifies the subcircuit by inserting analog switches in front of the cells that need to be sensitized, so that the analog switches can be used to apply a sensitization sequence to the cells during the transistor-level simulation. The embodiment can then generate a transistor-level description of the modified subcircuit. Next, the transistor-level description of the subcircuit can be stored, thereby enabling the transistor-level simulator to simulate the subcircuit.
摘要翻译：本发明的一个实施例提供了用于产生子电路的晶体管级描述的系统和技术。用户可能需要使用晶体管级模拟器来模拟电路中的分支电路，并且子电路中的一个或多个单元可能需要被敏化，使得当模拟子电路时，单元格处于期望状态。实施例通过将模拟开关插入需要敏化的单元前面来修改子电路，使得模拟开关可用于在晶体管级仿真期间向单元施加致敏序列。然后，该实施例可以生成修改后的子电路的晶体管级描述。接下来，可以存储子电路的晶体管级描述，从而使晶体管级模拟器能够模拟子电路。

14. 发明申请

US20090294655A1 ION TRAP ARRAY 有权
标题翻译：离子束阵列
公开(公告)号：US20090294655A1
公开(公告)日：2009-12-03
申请号：US12298968
申请日：2007-04-13
申请人： Chuanfan Ding , Li Ding
发明人： Chuanfan Ding , Li Ding
IPC分类号： B01D59/44 , H01J49/00
CPC分类号： H01J49/4225 , H01J49/004 , H01J49/065 , H01J49/4235
摘要： The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays
摘要翻译：本发明“离子阱阵列（ITA）”一般涉及离子存储和分析技术领域，特别涉及离子存储装置和质谱仪器，它们通过诸如质荷比的特性分离离子。本发明的目的是提供一种用于离子存储和分析的装置，其包括至少两行或多行平行放置的电极阵列，其中每个电极阵列包括至少两个或更多个平行的棒状电极，通过施加不同相位的交流电压在不同的棒电极上在不同行电极阵列的两个平行电极之间的空间内部产生交替电场，多个线性离子俘获场平行地构造在电极阵列的不同行之间的空间中，这些空间彼此相邻而没有实际屏障。本发明还提供一种离子存储和分析的方法，其涉及通过所述装置进行的捕获，冷却和质量选择的离子分析，其构造了在不同行电极阵列之间的空间中的多个联合线性离子捕获场

15. 发明申请

US20090287306A1 Optical hydrogel material with photosensitizer and method for modifying the refractive index 有权
$Optical hydrogel material with photosensitizer and method for modifying the refractive index$
标题翻译：具有光敏剂的光学水凝胶材料和用于改变折射率的方法
公开(公告)号：US20090287306A1
公开(公告)日：2009-11-19
申请号：US12380892
申请日：2009-03-04
申请人： Thomas Smith , Wayne H. Knox , Li Ding , Dharmendra Jani , Jeffrey G. Linhardt
发明人： Thomas Smith , Wayne H. Knox , Li Ding , Dharmendra Jani , Jeffrey G. Linhardt
IPC分类号： A61F2/16 , B29D11/00 , A61F2/14
CPC分类号： A61F9/00804 , A61F2/1451 , A61F2/1627 , A61F2/1635 , A61L27/50 , A61L27/52 , A61L2430/16 , B29D11/00009 , G02C2202/14
摘要： A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.
摘要翻译：一种用于改变光学水凝胶聚合物材料的折射率的方法。该方法包括用激光照射光学聚合材料的预定区域以形成折射结构。为了促进折射结构的形成，光学水凝胶聚合物材料包含光敏剂。光敏剂的存在允许将扫描速率设置为比材料中没有光敏剂的扫描速率至少大五十倍的值，但是根据观察到的折射率变化提供相似的折射结构。或者，聚合物材料中的光敏剂允许将平均激光功率设置为比平均激光功率小至少两倍的值，而不需要材料中的光敏剂，但是提供类似的折射结构。

16. 发明授权

US07608704B2 Secreted proteins 失效
标题翻译：分泌蛋白
公开(公告)号：US07608704B2
公开(公告)日：2009-10-27
申请号：US11378616
申请日：2006-03-20
申请人： Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan M. Sanjanwala , Michael Thorton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
发明人： Henry Yue , Monique G. Yao , Ameena R. Gandhi , Mariah R. Baughn , Anita Swarnakar , Narinder Chawla , Madhusudan M. Sanjanwala , Michael Thorton , Vicki S. Elliott , Yan Lu , Kimberly J. Gietzen , Neil Burford , Li Ding , April J. A. Hafalia , Y. Tom Tang , Olga Bandman , Bridget A. Warren , Cynthia D. Honchell , Dyung Aina M. Lu , Kavitha Thangavelu , Sally Lee , Yuming Xu , Junming Yang , Preeti G. Lal , Bao Tran , Craig H. Ison , Brendan M. Duggan , Stephanie K. Sapperstein
IPC分类号： C07H21/04 , C12N15/00 , C12P21/04
CPC分类号： C12N15/1055 , A61K39/3955 , A61K47/64 , A61K47/643 , A61K2039/505 , C07K14/47 , C07K14/4711 , C07K14/4713 , C07K16/18 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/622 , C07K2317/75 , C07K2317/76 , G01N33/5023
摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.
摘要翻译：本发明提供鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。本发明还提供用于诊断，治疗或预防与SECP异常表达相关的疾病的方法。

17. 发明申请

US20090089729A1 Distorted Waveform Propagation and Crosstalk Delay Analysis Using Multiple Cell Models 有权
标题翻译：使用多个单元模型的失真波形传播和串扰延迟分析
公开(公告)号：US20090089729A1
公开(公告)日：2009-04-02
申请号：US11863252
申请日：2007-09-28
申请人： Li Ding , Peivand Tehrani , Jindrich Zejda , Alireza Kasnavi
发明人： Li Ding , Peivand Tehrani , Jindrich Zejda , Alireza Kasnavi
IPC分类号： G06F17/50
CPC分类号： G06F17/5031
摘要： A method to perform timing analysis for a complex logic cell with distorted input waveform and coupled load networks is presented. Timing arc based models are used in conjunction with CCB based current models of portions of the logic cell to compute the output signal of the logic cell. For example, an intermediary signal is generated using a first timing arc based model and an equivalent coupled network output signal is generated using a channel connected block (CCB) based current model.
摘要翻译：提出了一种对具有失真输入波形和耦合负载网络的复杂逻辑单元执行定时分析的方法。基于时间弧的模型与基于CCB的当前模型的逻辑单元的部分结合使用以计算逻辑单元的输出信号。例如，使用基于第一定时弧的模型生成中间信号，并且使用基于信道连接块（CCB）的当前模型生成等效的耦合网络输出信号。

18. 发明授权

US07479781B2 System and method for testing a link control card 失效
标题翻译：用于测试链路控制卡的系统和方法
公开(公告)号：US07479781B2
公开(公告)日：2009-01-20
申请号：US11440318
申请日：2006-05-24
申请人： Kang Wu , Wei Zhang , Jun Huang , Li Ding
发明人： Kang Wu , Wei Zhang , Jun Huang , Li Ding
IPC分类号： G01R31/00
CPC分类号： H04L43/50
摘要： A system and method for testing a Link Control Card (LCC) of a storage device includes a host, a middle plane (MP), a switch, and a testing device array. The host is connected to the testing device array for sending out command sets and receiving results. The MP is connected between the LCC and the testing device array. The switch determines the LCC to output hard reset signals and the hard reset signals are transferred to the testing device array via the MP. The testing device array includes a plurality of testing devices, and each of the testing devices includes a micro-controller unit (MCU); a connector being connected to the MCU, and coupled to the MP; an address setting unit being connected to the MCU, for setting an unique address of each of the testing devices; and a first interface being connected to the MCU for outputting results.
摘要翻译：用于测试存储设备的链路控制卡（LCC）的系统和方法包括主机，中间平面（MP），交换机和测试设备阵列。主机连接到测试设备阵列，用于发送命令集和接收结果。 MP连接在LCC和测试设备阵列之间。该开关确定LCC输出硬复位信号，硬复位信号通过MP传输到测试器件阵列。测试装置阵列包括多个测试装置，并且每个测试装置包括微控制器单元（MCU）; 连接器连接到MCU，并连接到MP; 连接到MCU的地址设置单元，用于设置每个测试设备的唯一地址; 以及连接到MCU的第一接口，用于输出结果。

19. 发明申请

US20080241158A1 Human taste-specific receptor TIR3 审中-公开
标题翻译：人类特异性受体TIR3
公开(公告)号：US20080241158A1
公开(公告)日：2008-10-02
申请号：US11896125
申请日：2007-08-29
申请人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
发明人： Preeti G. Lal , Richard C. Graul , April J.A. Hafalia , Narinder K. Chawla , Michael B. Thornton , Danniel B. Nguyen , Yan Lu , Ameena R. Gandhi , Chandra S. Arvizu , Deborah A. Kallick , Mariah R. Baughn , Jayalaxmi Ramkumar , Catherine M. Tribouley , Ernestine A. Lee , Li Ding , Neil Burford , Monique G. Yao , Junming Yang , Jennifer A. Griffin
IPC分类号： A61K39/395 , C07K14/00 , C07H21/00 , C12N1/21 , C12P21/00 , C07K16/00 , C07K1/14 , A61P35/00 , A61P25/00 , A61P9/00 , G01N33/00 , G01N33/68 , C12Q1/68 , A61K38/16 , G01N33/53
CPC分类号： C07K14/705 , A61K38/00 , G01N2333/4719 , Y10T436/143333
摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译：本发明提供鉴定和编码GCREC的人G-蛋白偶联受体（GCREC）和多核苷酸。本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。本发明还提供用于诊断，治疗或预防与GCREC异常表达相关的疾病的方法。

20. 发明申请

US20050202478A1 Phosphodiesterases 审中-公开
标题翻译：磷酸二酯酶
公开(公告)号：US20050202478A1
公开(公告)日：2005-09-15
申请号：US11048068
申请日：2005-02-02
申请人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
发明人： Michael Thornton , Li Ding , Chandra Arvizu , Monique Yao , Catherine Tribouley , Preeti Lal , April Hafalia , Mariah Baughn , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla
IPC分类号： A61K38/00 , C12N9/16 , C12Q1/68 , A01K67/00 , C07H21/04
CPC分类号： C12N9/16 , A61K38/00
摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.
摘要翻译：本发明提供了人类磷酸二酯酶（HPDE）和识别和编码HPDE的多核苷酸。本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。本发明还提供用于诊断，治疗或预防与HPDE异常表达相关的疾病的方法。

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