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11. 发明申请

US20110092798A1 METHOD FOR MAGNETIC RESONANCE ELASTOGRAPHY INVERSION USING A FINITE MEDIUM MODEL 有权
标题翻译：使用有限介质模型进行磁共振ELASTOGRAPHY反演的方法
公开(公告)号：US20110092798A1
公开(公告)日：2011-04-21
申请号：US12935968
申请日：2009-04-03
申请人： Arunark Kolipaka , Armando Manduca , Kiaran P. Mcgee , Richard L. Ehman , Kevin J. Glaser
发明人： Arunark Kolipaka , Armando Manduca , Kiaran P. Mcgee , Richard L. Ehman , Kevin J. Glaser
IPC分类号： A61B5/055
CPC分类号： G01R33/56358 , A61B5/0051 , A61B5/416
摘要： A method for magnetic resonance elastography (“MRE”) is described, in which an MRE inversion that accounts for waves propagating in a finite, bounded media is employed. A vibratory motion is induced in a subject and MRE is performed to measure one or more components of the resulting displacement produced in the subject. This displacement data is subsequently filtered to provide a more accurate and computationally efficient method of inversion. Wave equations based on the geometry of the bounded media are then utilized to calculate the material properties of the subject. Such a method allows for the performance of MRE on tissues such as the heart, eye, bladder, and prostate with more accurate results.
摘要翻译：描述了一种用于磁共振弹性成像（“MRE”）的方法，其中采用考虑在有限的有界介质中传播的波的MRE反演。在受试者中诱发振动，并执行MRE以测量在受试者中产生的所得到的位移的一个或多个成分。随后对该位移数据进行滤波以提供更精确和计算上有效的反演方法。然后利用基于有界介质的几何形状的波动方程来计算受试者的材料性质。这种方法允许在更精确的结果上在诸如心脏，眼睛，膀胱和前列腺的组织上表现MRE。

12. 发明授权

US06469506B1 Autocorrection of MR images acquired using phased-array coils 有权
标题翻译：使用相控阵线圈获得的MR图像的自动校正
公开(公告)号：US06469506B1
公开(公告)日：2002-10-22
申请号：US09595272
申请日：2000-06-15
申请人： Joel P. Felmlee , Kiaran P. McGee , Richard L. Ehman , Armando Manduca
发明人： Joel P. Felmlee , Kiaran P. McGee , Richard L. Ehman , Armando Manduca
IPC分类号： G01V300
CPC分类号： G01R33/3415
摘要： An MRI image acquired with a phase-array coil is corrected for motion artifacts using an iterative, autocorrection process in which corrections are tried and the quality of the resulting reconstructed image is measured. In one embodiment autocorrections are calculated for the data acquired with one coil element and the same corrections are made to data acquired with the other coil elements. In another embodiment autocorrections are calculated separately for the data acquired with each coil element. In either embodiment, the separate corrected images are combined to form the output image.
摘要翻译：用相位阵列线圈获取的MRI图像使用迭代自动校正过程来校正运动伪像，其中尝试校正并测量所得到的重建图像的质量。在一个实施例中，对于用一个线圈元件获取的数据计算自动校正，并且对与其它线圈元件获取的数据进行相同的校正。在另一个实施例中，为每个线圈元件采集的数据分别计算自动校正。在任一实施例中，组合分离的校正图像以形成输出图像。

13. 发明申请

US20160253825A1 SYSTEM AND METHOD FOR MODEL-BASED RECONSTRUCTION OF QUANTITATIVE IMAGES 审中-公开
标题翻译：基于模型的量化图像重建系统与方法
公开(公告)号：US20160253825A1
公开(公告)日：2016-09-01
申请号：US15032938
申请日：2014-10-22
申请人： Joshua D. TRZASKO , Armando MANDUCA
发明人： Joshua D. Trzasko , Armando Manduca
IPC分类号： G06T11/00 , A61B5/00 , G06T7/00
CPC分类号： G06T11/003 , A61B5/743 , G01R33/5608 , G06T7/0012 , G06T7/0016 , G06T2207/10076 , G06T2207/10088 , G06T2207/10092
摘要： A system and method for estimating a physiological parameter from data acquired with a medical imaging system includes acquiring data with the medical imaging system. A physiological parameter is estimated from the acquired data using an iterative estimation in which a model of the medical imaging system is decoupled from a physics-based model of the acquired data.
摘要翻译：从用医学成像系统获取的数据估计生理参数的系统和方法包括用医学成像系统获取数据。使用迭代估计从所获取的数据估计生理参数，其中医学成像系统的模型与所获取的数据的基于物理的模型解耦。

14. 发明申请

US20150309136A1 Systems and Methods for Efficiently Generating Magnetic Resonance Images from Incomplete Data 审中-公开
标题翻译：从不完整的数据有效地产生磁共振图像的系统和方法
公开(公告)号：US20150309136A1
公开(公告)日：2015-10-29
申请号：US14694621
申请日：2015-04-23
申请人： Yunhong Shu , Armando Manduca , Joshua D. Trzasko , Matthew A. Bernstein
发明人： Yunhong Shu , Armando Manduca , Joshua D. Trzasko , Matthew A. Bernstein
IPC分类号： G01R33/48 , G01R33/36 , G01R33/561 , G01R33/385 , G01R33/56
CPC分类号： G01R33/4826 , G01R33/5611
摘要： Systems and methods for efficiently generating MR images are provided. The method comprises acquiring k-space MR data, reconstructing an MR image from the k-space MR data, and generating the MR image. The MR image is reconstructed using an alternative-direction-method-of-multiplier (ADMM) strategy that decomposes an optimization problem into subproblems, and at least one of the subproblems is further decomposed into small problems. The further decomposition is based on Woodbury matrix identity and uses a diagonal preconditioner based on non-Toeplitz models.
摘要翻译：提供了有效产生MR图像的系统和方法。该方法包括获取k空间MR数据，从k空间MR数据重建MR图像，以及生成MR图像。使用将优化问题分解为子问题的替代方向乘法器（ADMM）策略重构MR图像，并且至少一个子问题进一步分解为小问题。进一步分解是基于Woodbury矩阵身份，并使用基于非Toeplitz模型的对角预处理器。

15. 发明申请

US20100142783A1 AXIAL CENTERLINE FOLLOWING DISPLAY OF CT COLONOGRAPHY IMAGES 审中-公开
标题翻译：以下关于CT组合图像显示的轴向中心
公开(公告)号：US20100142783A1
公开(公告)日：2010-06-10
申请号：US12523474
申请日：2008-01-22
申请人： C. Daniel Johnson , Michael J. Carston , Armando Manduca , Robert J. Wentz
发明人： C. Daniel Johnson , Michael J. Carston , Armando Manduca , Robert J. Wentz
IPC分类号： G06K9/00
CPC分类号： G06T19/00 , G06T2210/41 , G06T2219/008
摘要： A method for displaying colonography images includes presenting a series of axial images of the colon at sequential locations along the colon centerline. Each image is generally centered on the centerline and presents a field of view parallel to the axial plane.
摘要翻译：用于显示结肠图像的方法包括在结肠中心线的顺序位置呈现一系列结肠的轴向图像。每个图像通常以中心线为中心，并呈现平行于轴向平面的视场。

16. 发明授权

US07127092B2 Reduction of motion artifact in NMR images using spherical navigator signals 有权
标题翻译：使用球形导航信号减少NMR图像中的运动伪影
公开(公告)号：US07127092B2
公开(公告)日：2006-10-24
申请号：US10258268
申请日：2001-04-16
申请人： Clifford R. Jack , Armando Manduca , Roger Grimm , Edward B. Welch
发明人： Clifford R. Jack , Armando Manduca , Roger Grimm , Edward B. Welch
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/7207 , G01R33/56509 , G01R33/5676 , Y10T436/24
摘要： A series of fMRI image frames are acquired along with interleaved navigator signals. The navigator signals are acquired while three orthogonal readout gradients are applied such that a spherical surface is sampled in k-space. The navigator signals are analyzed to measure subject rotational and translational motion during the scan.
摘要翻译：一系列fMRI图像帧与交错导航信号一起被采集。获取导航信号，同时施加三个正交读出梯度，使得球面在k空间中被采样。分析导航信号以测量扫描期间的主体旋转和平移运动。

17. 发明授权

US08989465B2 System and method for medical image reconstruction and image series denoising using local low rank promotion 有权
标题翻译：用于医学图像重建的系统和方法以及使用本地低级推广的图像序列去噪
公开(公告)号：US08989465B2
公开(公告)日：2015-03-24
申请号：US13743465
申请日：2013-01-17
申请人： Joshua D. Trzasko , Armando Manduca
发明人： Joshua D. Trzasko , Armando Manduca
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/003 , G06T11/006 , G06T2211/412 , G06T2211/424
摘要： A method for reconstructing a time series of images from data acquired with a medical imaging system is provided. Data is acquired with the medical imaging system, and a set of image blocks that defines the location and size of each of a plurality of image blocks in the image domain is then selected. The acquired data and selected image block set are then used to jointly estimate a plurality of images that form a time series of images while promoting locally-low rank structure in the images.
摘要翻译：提供了一种用于从用医学成像系统获取的数据重建图像的时间序列的方法。然后，利用医学成像系统获取数据，然后选择定义图像域中的多个图像块中的每一个的位置和大小的一组图像块。所获取的数据和所选择的图像块集合然后用于联合估计形成图像的时间序列的多个图像，同时促进图像中的局部低秩结构。

18. 发明授权

US08653816B2 Physical motion information capturing of a subject during magnetic resonce imaging automatically motion corrected by the magnetic resonance system 失效
标题翻译：在由磁共振系统校正的磁共振成像期间自动运动的被摄物体的物理运动信息捕获
公开(公告)号：US08653816B2
公开(公告)日：2014-02-18
申请号：US12612172
申请日：2009-11-04
申请人： David S. Lake , Armando Manduca , Jeffrey S. McAllister , Nelson Ramirez
发明人： David S. Lake , Armando Manduca , Jeffrey S. McAllister , Nelson Ramirez
IPC分类号： G01R33/565
CPC分类号： G01R33/56509
摘要： Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. Motion information may be received for the subject. Based on the received motion information, a translational motion of the subject may be determined between a first point in time and a second point in time. A search space for motion correction may be reduced using the determined change and an error margin of the capturing technique. A motion-compensated, graphical image of the subject may be generated using the reduced search space.
摘要翻译：公开了用于在对象的MRI扫描期间补偿对象的运动的系统，方法和制品。可以从对象的MRI扫描接收k空间数据。运动信息可能会被收到。基于接收到的运动信息，可以在第一时间点和第二时间点之间确定对象的平移运动。可以使用确定的改变和捕获技术的误差范围来减少用于运动校正的搜索空间。可以使用缩小的搜索空间来生成被摄体的运动补偿的图形图像。

19. 发明授权

US08442290B2 Simultaneous dual window/level settings for display of CT colonography images 有权
标题翻译：同时双窗口/级别设置显示CT结肠图像
公开(公告)号：US08442290B2
公开(公告)日：2013-05-14
申请号：US12523465
申请日：2008-01-22
申请人： C. Daniel Johnson , Michael J. Carston , Armando Manduca
发明人： C. Daniel Johnson , Michael J. Carston , Armando Manduca
IPC分类号： G06K9/00
CPC分类号： G06T19/00 , G06T2210/41
摘要： A method for processing and displaying colonography image data. First distance tissue pixels representative of tissue within a first distance of gas pixels representative of gas are processed with a first window/level setting to generate a first setting set of image pixels. Second distance tissue pixels representative of tissue within a second distance of the gas pixels are processed with a second window/level setting to generate a second setting set of image pixels. The second distance is a distance greater than the first distance. A colonography image including both the first and second setting sets of image pixels is then displayed.
摘要翻译：一种处理和显示结肠图像数据的方法。代表气体的气体像素的第一距离内的组织的第一距离组织像素用第一窗口/等级设置进行处理，以生成图像像素的第一设置集合。代表气体像素的第二距离内的组织的第二距离组织像素用第二窗口/等级设置进行处理，以生成图像像素的第二设置集合。第二距离是大于第一距离的距离。然后显示包括图像像素的第一和第二设置组的结构图像。

20. 发明授权

US08031921B2 Electronic stool subtraction in CT colonography 有权
标题翻译：电子粪便减法CT结肠造影
公开(公告)号：US08031921B2
公开(公告)日：2011-10-04
申请号：US11816264
申请日：2006-02-14
申请人： Armando Manduca , Michael J. Carston , Robert J. Wentz , C. Daniel Johnson
发明人： Armando Manduca , Michael J. Carston , Robert J. Wentz , C. Daniel Johnson
IPC分类号： G06K9/00
CPC分类号： G06T5/005 , G06T5/30 , G06T7/11 , G06T7/155 , G06T7/174 , G06T2207/10081 , G06T2207/20224 , G06T2207/30028
摘要： A method for processing CT colonography input image voxel data representative of 3-dimensional images of a colon having gas and stool tagged with stool tagging agent, to remove the stool from the images. The input image voxel data is generated by an imaging instrument having a characteristic point spread function representative of instrument blurring. The point spread function of the instrument can be empirically determined, and the image data processed as a function of the point spread function to accurately identify and remove the tagged stool. In one embodiment of the invention, portions of the image data representative of the tagged stool and colon tissue are dilated as a function of the point spread function. In another embodiment, portions of the image data representative of the tagged stool are convolved with the point spread function to determine the fractional amount of stool present in the image portions, and the tagged stool subtracted by reducing the intensities of the associated portions of the image by an amount proportional to the fractional amount of stool present.
摘要翻译：一种用于处理CT结肠造影输入图像体素数据的方法，其代表具有标记有粪便标记剂的气体和粪便的结肠的3维图像，以从图像中去除粪便。输入图像体素数据由具有代表仪器模糊的特征点扩散函数的成像仪生成。仪器的点扩散函数可以根据经验确定，并且图像数据作为点扩散函数的函数进行处理，以准确识别和移除标记的粪便。在本发明的一个实施例中，代表标记的粪便和结肠组织的图像数据的部分作为点扩散函数的函数被扩张。在另一个实施例中，代表标记的凳子的图像数据的部分与点扩散函数进行卷积，以确定图像部分中存在的粪便的分数，并且通过降低图像的相关部分的强度来减去标记的粪便通过与存在的粪便的分数量成比例的量。

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